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Ultrastructural Pathology Volume 33, 2009 - Issue 4
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Research Article

Identification of Cancer Stem-like Side Population Cells in Ovarian Cancer Cell Line OVCAR-3

Quanli GaoDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Henan, China; Department of Hematology, Henan Tumor Hospital, Zhengzhou, Henan, China; Department of Immunology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway; and Faculty Division of the Norwegian Radium Hospital, Faculty of Medicine, University of Oslo, Oslo, Norway
, MD, PhD,
Li GengDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Henan, China; Department of Immunology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway; and Faculty Division of the Norwegian Radium Hospital, Faculty of Medicine, University of Oslo, Oslo, Norway
, MD,
Gunnar KvalheimDepartment of Cell Therapy, The Norwegian Radium Hospital, Oslo University Hospital, Montebello, Norway
, MD, PhD,
Gustav GaudernackDepartment of Immunology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway; and Faculty Division of the Norwegian Radium Hospital, Faculty of Medicine, University of Oslo, Oslo, Norway
, PhD &
Zhenhe SuoDivision of Pathology, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway; and Faculty Division of the Norwegian Radium Hospital, Faculty of Medicine, University of Oslo, Oslo, NorwayCorrespondence[email protected]
, MD, PhD
Pages 175-181 | Received 28 Apr 2009, Accepted 28 May 2009, Published online: 06 Nov 2009

REFERENCES

  • Tu SM, Lin SH, Logothetis CJ. Stem-cell origin of metastasis and heterogeneity in solid tumors. Lancet Oncol. 2002;3:508–513.
  • Reya T, Morrison SJ, Clarke MF, et al. Stem cells, cancer, and cancer stem cells. Nature. 2001;415:105–111.
  • Singh SK, Clarke ID, Terasaki M, et al. Identification of a cancer stem cell in human brain tumors. Cancer Res. 2003;63:5821–5828.
  • O'Brien CA, Pollett A, Gallinger S, et al. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature. 2007;445:106–110.
  • Collins AT, Berry PA, Hyde C, et al. Prospective idntification of tum-origenic prostate cancer stem cells. Cancer Res. 2005;65:10946–10951.
  • Prince ME, Sivanandan R, Kaczorowski A, et al. Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc Natl Acad Sci USA. 2007;104:973–978.
  • Al-Hajj M, Wicha MS, Benito-Hernandez A, et al. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA. 2003;100:3983–3988.
  • Zhang S, Balch C, Chan MW, et al. Identification and characterization of ovarian cancer-initiating cells from primary human tumors. Cancer Res. 2008;68:4311–4320.
  • Shmelkov SV, Butler JM, Hooper AT, et al. CD133 expression is not restricted to stem cells, and both CD133 and CD133 metastatic colon cancer cells initiate tumors. J Clin Invest. 2008;118:2111–2120.
  • Mack B, Gires O. CD44s and CD44v6 expression in head and neck epithelia. PLoS ONE. 2008;3:3360–3369.
  • Goodell MA, Brose K, Paradis G, Conner AS, Mulligan RC. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med. 1996;183:1797–1806.
  • Pecorelli S, Favalli G, Zigliani L, Odicino F. Cancer in women. Int J Gynaecol Obstet. 2003;82:369–379.
  • Moserle L, Indraccolo S, Ghisi M, et al. The side population of ovarian cancer cells is a primary target of IFN-alpha antitumor effects. Cancer Res. 2008;68:5658–5668.
  • Wang Q, He W, Lu C, et al. Oct3/4 and Sox2 are significantly associated with an unfavorable clinical outcome in human squamous cell carcinoma. Anticancer Res. 2009;29:1233–1241.
  • Chiba T, Kita K, Zheng YW, et al. Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties. Hepatology. 2006;44:240–251.
  • Huang D, Gao Q, Guo L, et al. Isolation and identification of cancer stem-like cells in esophageal carcinoma cell lines. Stem Cells Dev. 2009;18:93–101.
  • Zhou S, Schuetz JD, Bunting KD. The ABC transporter Bcrp1/ ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med. 2001;7:1028–1034.
  • Li H, Chen X, Calhoun-Davis T, et al. PC3 human prostate carcinoma cell holoclones contain self-renewing tumor-initiating cells. Cancer Res. 2008;68:1820–1825.

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