207
Views
52
CrossRef citations to date
0
Altmetric
Original

Novel dithranol phospholipid microemulsion for topical application: development, characterization and percutaneous absorption studies

, , , , &
Pages 190-199 | Received 25 Jun 2010, Accepted 03 Dec 2010, Published online: 18 May 2011

References

  • Aboofazeli R, Lawrence CB, Wicks SR, Lawrence MJ. Investigations into the formation and characterization of phospholipid microemulsions. III. Pseudo-ternary phase diagrams of systems containing water-lecithin-IPM and either an alkanoic acid, amine, alkanediol, polyethylene glycol alkyl ether or alcohol as cosurfactant. Int J Pharm 1994; 111: 63–72
  • Agarwal R, Katare OP, Vyas SP. Preparation and in vitro evaluation of liposomal/niosomal delivery systems for antipsoriatic drug dithranol. Int J Pharm 2001; 228: 43–52
  • Azeem A, Khan ZI, Aqil M, Ahmad FJ, Khar RK, Talegaonkar S. Microemulsions as a surrogate carrier for dermal drug delivery. Drug Dev Ind Pharm 2009; 35: 525–47
  • Changez M, Varshney M. Aerosol-OT microemulsions as transdermal carriers of tetracaine hydrochloride. Drug Dev Ind Pharm 2000; 26: 507–12
  • Cilek A, Celebi N, Tirnaksiz F. Lecithin-based microemulsion of a peptide for oral administration: Preparation, characterization, and physical stability of the formulation. Drug Delivery 2006; 13: 19–24
  • Craig DQM, Barker SA, Banning D, Booth SW. An investigation into the mechanisms of self-emulsification using particle size analysis and low frequency dielectric spectroscopy. Int J Pharm 1995; 114: 103–10
  • Delgado-Charro MB, Iglesias-Vilas G, Blanco-Méndez J, López Quintela MA, Marty JP, Guy RH. Delivery of a hydrophilic solute through the skin from novel microemulsion systems. Eur J Pharm Biopharm 1997; 43: 37–42
  • Gasco MR. Microemulsions in the pharmaceutical: Industrial applications of microemulsions. Marcel Dekker Inc, New YorkUSA 1997
  • Heuschkel S, Wohlrab J, Schmaus G, Neubert RHH. Modulation of dihydroavenanthramide D release and skin penetration by 1,2-alkanediols. Eur J Pharm Biopharm 2008; 70: 239–47
  • Hiller C, Campbell C, Smeaton I. How stable is dithranol? An investigation into the degradation of different dithranol formulations. Pharm Pract 1995; 5: 428–31
  • Hua L, Weisan P, Jiayu L. Preparation, evaluation and NMR characterization of vinpocetine microemulsion for transdermal delivery. Drug Dev Ind Pharm 2004; 30: 657–66
  • Kawakami K, Yoshikawa T, Moroto EK, Takahashi K, Nishihara Y, Masuda K. Microemulsion formulation for enhanced absorption of poorly soluble drugs I. Prescription design, J Controlled Release 2002; 81: 65–74
  • Kelmann RG, Kuminek G, Teixeira HF, Koester LS. Carbamazepine parenteral nanoemulsions prepared by spontaneous emulsification process. Int J Pharm 2007; 342: 231–39
  • Kogan A, Garti N. Microemulsions as transdermal drug delivery vehicles. Adv Colloid Interface Sci 2006; 123–126: 369–85
  • Kreilgaard M. Influence of microemulsions on cutaneous drug delivery. Adv Drug Delivery Rev 2002; 54: 77–98
  • Kreilgaard M, Pedersen EJ, Jaroszewski JW. NMR characterisation and transdermal drug delivery potential of microemulsion systems. J Controlled Release 2000; 69: 421–33
  • Ktistis G. A viscosity study on oil-in-water microemulsions. Int J Pharm 1990; 61: 213–18
  • Lawrence MJ, Rees GD. Microemulsion-based media as novel drug delivery systems. Adv Drug Delivery Rev 2000; 45: 89–121
  • Lin CC, Lin HY, Chen HC, Yu MW, Lee MH. Stability and characterisation of phospholipid-based curcumin-encapsulated microemulsions. Food Chem 2009; 116: 923–28
  • Lundberg B. Preparation of drug-carrier emulsions stabilized with phosphatidylcholine-surfactant mixtures. J Pharm Sci 1994; 83: 72–5
  • Magdassi S, Siman-Tov A. Formation and stabilization of perfluorocarbon emulsions. Int J Pharm 1990; 59: 69–72
  • Malcolmson C, Satra C, Kantaria S, Sidhu A, Lawrence MJ. Effect of oil on the level of solubilization of testosterone propionate into nonionic oil-in-water microemulsions. J Pharm Sci 1998; 87: 109–16
  • Mohammed C, Manoj V. Aerosol-OT microemulsions as transdermal carriers of tatracaine hydrochloride. Drug Dev Ind Pharm 2000; 26: 507–12
  • Moreno MA, Ballesteros MP, Frutos P. Lecithin-based oil-in-water microemulsions for parenteral use: Pseudo ternary phase diagrams, characterization and toxicity studies. J Pharm Sci 2003; 92: 1428–37
  • Mustakalio KK. Irritation, staining and antipsoriatic activity of 10-acyl analogue of anthralin. Br J Dermatol 1981; 105: 23–7
  • Paolino D, Ventura CA, Nisticò S, Puglisi G, Fresta M. Lecithin microemulsions for the topical administration of ketoprofen: percutaneous adsorption through human skin and in vivo human skin tolerability. Int J Pharm 2002; 244: 21–131
  • Peltola S, Saarinen-Savolainen P, Kiesvaara J, Suhonen TM, Urtti A. Microemulsions for topical delivery of estradiol. Int J Pharm 2003; 254: 99–107
  • Ruth HS, Attwood D, Ktistis G, Taylor CJ. Phase studies and particle diameter analysis of oil-in-water phospholipid microemulsions. Int J Pharm 1995; 116: 253–61
  • Shinoda K, Kaneko TJ. Characteristic properties of lecithin as a surfactant. J Dispersion Sci Technol 1988; 5: 555–9
  • Singh B, Mehta G, Kumar R, Bhatia A, Ahuja N, Katare OP. Design, development and optimization of nimuslide-loaded liposomal systems for topical applications. Curr Drug Delivery 2005; 2: 143–53
  • Sintov AC, Shapiro L. New microemulsion vehicle facilitates percutaneous penetration in vitro and cutaneous drug bioavailability in vivo. J Controlled Release 2004; 95: 173–83
  • Skiba M, Duchêne D, Puisieux F, Wouessidjewe D. Development of a new colloidal drug carrier from chemically-modified cyclodextrins: Nanospheres and influence of physicochemical and technological factors on particle size. Int J Pharm 1996; 129: 113–21
  • Stilbs P, Lindman B, Rapacki K. Effect of alcohol cosurfactant length on microemulsion structure. J Colloid Interface Sci 1983; 95: 583–5
  • Subramanium N, Ray S, Ghosal SK, Bhadra R, Moulik SP. Formulation design of self-microemulsifying drug delivery systems for improved oral bioavailability of Celecoxib. Biol Pharm Bull 2004; 27: 1993–9
  • Wang JCT, Patel BG, Ehman CW, Lowe N. The release and percutaneous permeation of anthralin products, using clinically involved and uninvolved psoriatic skin. J Am Acad Dermatol 1987; 16: 812–20
  • Williams AC, Barry BW. Penetration enhancers. Adv Drug Delivery Rev 2004; 56: 603–18
  • Yokomizo Y, Sagitani H. The effects of phospholipids on the percutaneous penetration of indomethacin through the dorsal skin of guinea pig in vitro. 2. The effects of the hydrophobic group in phospholipids and a comparison with general enhancers. J Controlled Release 1996; 42: 37–46
  • Yuan Y, Li SM, Mo FK, Zhang DF. Investigation of microemulsion system for transdermal delivery of meloxicam. Int J Pharm 2006; 321: 117–23
  • Zhang XC, Jackson JK, Burt HM. Development of amphiphilic diblock copolymers as micellar carriers of taxol. Int J Pharm 1996; 132: 195–206

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.