776
Views
102
CrossRef citations to date
0
Altmetric
Research Article

Preparation and characterization of spray dried inhalable powders containing chitosan nanoparticles for pulmonary delivery of isoniazid

, , , , &
Pages 605-613 | Received 10 Jan 2011, Accepted 13 Jun 2011, Published online: 27 Jul 2011

References

  • Agnihotri SA, Mallikarjuna NN, Aminabhavi TM. Recent advances on chitosan-based micro- and nanoparticles in drug delivery. J Control Release 2004; 100: 5–28
  • Aktas Yi, Andrieux K, Alonso MJ, Calvo P, Gursoy RN, Couvreur P, Capan Y. Preparation and in vitro evaluation of chitosan nanoparticles containing a caspase inhibitor. Int J Pharm 2005; 298: 378–83
  • Azarmi S, Roa WH, Löbenberg R. Targeted delivery of nanoparticles for the treatment of lung diseases. Adv Drug Del Rev 2008; 60: 863–75
  • Bao D, Zhao Y. Building membrane emulsification into pulmonary drug delivery and targeting. Pharm Res 2010; 27: 2505–8
  • Du W-L, Niu S-S, Xu Y-L, Xu Z-R, Fan C-L. Antibacterial activity of chitosan tripolyphosphate nanoparticles loaded with various metal ions. Carbohydr Polym 2009; 75: 385–9
  • Elzatahry AA, Eldin MSM. Preparation and characterization of metronidazoleloaded chitosan nanoparticles for drug delivery application. Polym Adv Technol 2008; 19: 1787–91
  • Gan Q, Wang T, Cochrane C, McCrron P. Modulation of surface charge, particle size and morphological properties of chitosan–TPP nanoparticles intended for gene delivery. Colloids Surf B 2005; 44: 65–73
  • Gervelas C, Serandour AL, Geiger S, Grillon G, Fritsch P, Taulelle C, Gall BL, Benech H, Deverre JR, Fattal E, et al. Direct lung delivery of a dry powder formulation of DTPA with improved aerosolization properties: Effect on lung and systemic decorporation of plutonium. J Control Release 2007; 118: 78–86
  • Gilani K, Najafabadi AR, Barghi M, Rafiee-Tehrani M. Aerosolisation of beclomethasone dipropionate using spray dried lactose/polyethylene glycol carriers. Euro J Pharma Biopharm 2004; 58: 595–606
  • Grenha A, Seijo Bn, Remũn’an-Lo’pez C. Microencapsulated chitosan nanoparticles for lung protein delivery. Euro J Pharma Sci 2005; 25: 427–37
  • Helander IM, Miaho-Lassila EL, Ahvenainen R, Rhoades J, Roller S. Chitosan disrupts the barrier properties of the outer membrane of Gram-negative bacteria. Int J Food Microbiol 2001; 71: 235–44
  • Kawashima Y, Handa T, Takenaka H, Lin SY. Novel method for the preparation of controlled-release theophylline granules coated with a polyelectrolyte complex of sodium polyphosphate-chitosan. J Pharma Sci 1985; 74: 264–8
  • Ko JA, Park HJ, Hwang SJ, Park JB, Lee JS. Preparation and characterization of chitosan microparticles intended for controlled drug delivery. Int J Pharm 2002; 249: 165–74
  • Li HY, Seville PC, Williamson IJ, Birchall JC. The use of amino acids to enhance the aerosolisation of spray-dried owders for pulmonary gene therapy. J Gene Med 2005; 7: 343–53
  • Lo’pez-Leon T, Carvalho ELS, Seijo B, Ortega-Vinuesa JL, Gonza’lez DB. Physicochemical characterization of chitosan nanoparticles: Electrokinetic and stability behavior. J Colloid Interface Sci 2005; 283: 344–51
  • Pan Y, Li Y, Zhao H, Zheng J, Xu H, Wei G, Hao J, Cui F. Bioadhesive polysaccharide in protein delivery system: Chitosan nanoparticles improve the intestinal absorption of insulin in vivo. Int J Pharm 2002; 249: 139–47
  • Pandey R, Khuller GK. Antitubercular inhaled therapy: Opportunities, progress and challenges. Antimicrob Chemother 2005; 55: 430–5
  • Papadimitriou S, Bikiaris D, Avgoustakis K, Karavas E, Georgarakis M. Chitosan nanoparticles loaded with dorzolamide and pramipexole. Carbohydr Polym 2008; 73: 44–5
  • Pilcer G, Amighi K. Formulation strategy and use of excipients in pulmonary drug delivery. Int J Pharmaceut 2010; 392: 1–19
  • Rabbani NR, Seville PC. The influence of formulation components on the aerosolisation properties of spray-dried powders. J Control Release 2005; 110: 130–40
  • Shu XZ, Zhu KJ. A novel approach to prepare tripolyphosphate:chitosan complex beads for controlled release drug delivery. Int J Pharm 2000; 201: 51–8
  • Shu XZ, Zhu KJ. Chitosan/gelatin microspheres prepared by modified emulsification and ionotropic gelation. J Microencapsul 2001; 18: 237–45
  • Sung JC, Padilla DJ, Garcia-Contreras L, VerBerkmoes JL, Durbin D, Peloquin CA, Elbert KJ, Hickey AJ, Edwards DA. Formulation and pharmacokinetics of self-assembled rifampicin nanoparticle systems for pulmonary delivery. Pharm Res 2009; 26: 1847–55
  • Toossi Z, Ellner J, Friedman L. Tuberculosis: Current concepts and treatment. CRC Press, Boca Raton, FloridaUSA 2001
  • WHO. 2007. Tuberculosis fact sheet in World Health Organization, Geneva.
  • Zahoor A, Sharma S, Khuller GK. Inhalable alginate nanoparticles as antitubercular drug carriers against experimental tuberculosis. Int J Antimicrob Agents 2005; 26: 298–303
  • Zhou H, Zhang Y, Biggs DL, Manning MC, Randolph HW, Christians U, Hybertson BM, Ng K-Y. Microparticle-based lung delivery of INH decreases INH metabolism and targets alveolar macrophages. J Control Release 2005; 107: 288–99

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.