217
Views
8
CrossRef citations to date
0
Altmetric
Research Article

Cellular uptake and antitumour activity of paclitaxel incorporated into trilaurin-based solid lipid nanoparticles in ovarian cancer

, &
Pages 755-761 | Received 08 Aug 2012, Accepted 11 Mar 2013, Published online: 17 Apr 2013

References

  • Battaglia L, Gallarate M. Lipid nanoparticles: State of the art, new preparation methods and challenges in drug delivery. Expert Opin Drug Deliv, 2012;9(5):497–508
  • Fei X, Xu W, Lee MK. Preparation and characterization of tributyrin sub-micron emulsions as carriers for paclitaxel. J Pharm Invetig, 2011;41(5):295–300
  • Feng L, Mumper RJ. A critical review of lipid-based nanoparticles for taxane delivery. Cancer Lett, 2012. In press
  • Lee MK, Lim SJ, Kim CK. Preparation, characterization and in vitro cytotoxicity of paclitaxel-loaded sterically stabilized solid lipid nanoparticles. Biomaterials, 2007;28:2137–46
  • Liu Y, Zhang B, Yan B. Enabling anticancer therapeutics by nanoparticle carriers: The delivery of paclitaxel. Int J Mol Sci, 2011;12:4395–413
  • Martins S, Costa-Lima S, Carneiro T, Cordeiro-da-Silva A, Souto EB, Ferreira DC. Solid lipid nanoparticles as intracellular drug transporters: An investigation of the uptake mechanism and pathway. Int J Pharm, 2012;430:216–27
  • Müller RH, Heinemann S. Fat emulsions for parenteral nutrition II: Characterisation and physical long-term stability of Lipofundin MCT LCT. Clin Nutrit, 1992;11:223–72
  • Pathak K, Keshri L, Shah M. Lipid nanocarrieres: influence of lipids on product development and pharmacokinetics. Crit Rev Ther Drug Carriere Syst, 2011;28(4):357–93
  • Sahay G, Alakhova DY, Kabanov AV. Endocytosis of nanomedicines. J Control Rel, 2010;145:182–95
  • Schwarz C, Mehnert W, Lucks JS, Müller RH. Solid lipid nanoparticles (SLN) for controlled drug delivery. I. Production, characterization and sterilization. J Control Release, 1994;30:83–96
  • Shenoy VS, Rajyaguru TH, Gude RP, Murthy RS. Studies on paclitaxel-loaded glyceryl monostearate nanoparticles. J Microencapsul, 2009;26(6):471–8
  • Siekmann B, Westesen K. 1998. Submicron lipid suspensions (solid lipid nanoparticles) versus lipid nanoemulsions: similarities and differnces. In: Benita S, ed. Submicron emulsions in drug targeting and delivery. Amsterdam: Horwood Academic Publishers, pp. 205–18
  • Singh S, Dash AK. Paclitaxel in cancer treatment: Perspectives and prospects of its delivery challenges. Crit Rev Ther Drug Carrier Syst, 2009;26(4):333–72
  • Westesen K, Siekmann B. Investigation of the gel formation of phospholipid-stabilized solid lipid nanoparticles. Int J Pharm, 1997;151:35–45
  • Westesen K, Wehler T. Physicochemical characterization of a model intravenous oil-in-water emulsion. J Pharm Sci, 1992;81:777–86
  • Wu L, Tang C, Yin C. Folate-mediated solid liquid lipid nanoparticles for paclitaxel-coated poly(ethylene glycol). Drug Deliv Ind Pharm, 2010;36(4):439–48
  • Yuan H, Miao J, Du Y-Z, You J, Hu F-Q, Zeng S. Cellular uptake of solid lipid nanoparticles and cytotoxicity of encapsulated paclitaxel in A549 cancer cells. Int J Pharm, 2008;348:137–45

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.