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Research Article

Antineoplastic activity and toxicity of some alkylating cytostatics (Cyclophosphamide, CCNU, Cytostasan) encapsulated in liposomes in different murine tumour models

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Pages 77-87 | Received 08 Jan 1986, Accepted 07 Feb 1986, Published online: 27 Sep 2008

References

  • Anger G., Hesse P., Köhler P., Baufeld H. Klinischer Erfahrungsbericht über die Anwendung des neuen Zytostatikums 3393. Zeitschrift für die gesamte innere Medizin 1968; 23: 242–247
  • Arndt D., Fichtner I. Liposomen-Darstellung, Eigenschaften, Anwendung. Akademie-Verlag, Berlin 1986
  • Arndt D., Fichtner I., Reszka R., Elbe B. Darstellung, Eigenschaften und therapeutische Wirksamkeit von daunorubicinhaltigen Liposomen. Pharmazie 1983; 38: 331–335
  • Arnold W., Nowak C. Metastatic screening models. Antitumor Drug Therapy Reports 1976; 2: 69–70
  • Babbage J. W., Berenbaum M. C. Increased therapeutic efficiency of a lipidsoluble alkylating agent incorporated in liposomes. British Journal of Cancer 1982; 45: 830–834
  • Liposome Letters, A. D. Bangham. Academic Press, London 1983
  • Connors T. A. The Cancer Pharmacology Annual 2, B. A. Chabner, H. M. Pinedo. Elsevier/North-Holland, Amsterdam 1984
  • Coune A., Sculieh J. P., Frühling J., Stryckmans P., Brassinne C., Ruysschaert J. M., Hildebrand J. I.v. administration of a water-insoluble antimitotic compound entrapped in liposomes. Preliminary report on infusion of large volumes of liposomes to man. Cancer Treatment Reports 1983; 67: 1031–1033
  • Ellens H., Rustum Y., Mayhew E., Ledesma E. Distribution and metabolism of liposome-encapsulated and free 1-β — D-arabinofuranosylcytosin. Journal of Pharmacology and Experimental Therapeutics 1982; 222: 324–330
  • Fichtner I., Arndt D., Elbe B., Reszka R. Cardiotoxicity of free and liposomally encapsulated rubomycin (daunorubicin) in mice. Oncology 1984; 41: 363–369
  • Freise J., Müller W. H., Magerstedt P., Schmoll H. J. Pharmacokinetics of liposome encapsulated cisplatin in rats. Archives Internationales de Pharmacodynamic et de therapie 1982; 258: 180–192
  • Liposome Technology, G. Gregoriadis. CRC Press, Boca Raton 1984
  • Liposomes in Biological Systems, G. Gregoriadis, A. C. Allison. Wiley, Chichester 1980
  • Großmann A., Reszka R., Arndt D. Quantitative Bestimmung alkylierender Substanzen in Liposomen. Pharmazie 1984; 39: 719
  • Gutsche W., Jungstand W., Wohlrabe K. Vergleich der Wirkung von IMET 3393 mit Chlorambucil an einer Reihe von Transplantationstumoren. Zentralblatt für Pharmazie 1971; 110: 1033–1043
  • Inaba M., Yoshida N., Tsukagoshi S. Preferential action of liposome entrapped 1-(2-chlorethyl)-3-(4-methyl-cyclohexyl)-1-nitrosourea on lung metastases of Lewis lung carcinoma as compared with the free drug. Gann 1981; 72: 341–345
  • Drug Delivery Systems, R. L. Juliano. Oxford University Press, Oxford 1980
  • Khato J., Priester E. R., Sieber S. M. Enhanced lymph node uptake of melphalan following liposomal entrapment and effects on lymph node metastasis in rats. Cancer Treatment Reports 1982; 66: 517–527
  • Kirby C., Gregoriadis G. The effect of lipid composition of small unilamellar liposomes containing Melphalan and Vincristin on drug clearance after injection into mice. Biochemical Pharmacology 1983; 32: 609–619
  • Laduron C., Atassi G., Hildebrand J., Ruysschaert J. M., Coune A., Stryckmans P., Brassinne C. Chemotherapeutic efficacy of NocodazoleR encapsulated in liposomes on L 1210 murine leukemia. Research Communications in Chemical Pathology and Pharmacology 1983; 39: 419–436
  • Large P., Gregoriadis G. Phospholipid composition of small unilamellar liposomes containing Melphalan influences drug action in mice bearing PC 6 tumors. Biochemical Pharmacology 1983; 32: 1315–1317
  • Maral R., Bourut C., Chenu C., Mathe G., Bernon R., Lussan C., Imbach J. L., Schein P., Bothorel P. Comparison of the experimental antitumor activities of three nitrosourea derivatives Chlorozoticin, RFCNU and CNCC encapsulated in liposomes with those in the free state. Oncology 1985; 4: 122–128
  • Mathe G., Bothorel P. In vivo enhancement of the experimental oncostatic effect of RFCNU by its encapsulation in liposomes. Biomedicine 1981; 35: 201–202
  • Nuhn P., Schenk P., Richter H., Arndt D., Jandrig J., Winsel K. Untersuchungen an Liposomen aus hydriertem Eilecithin. Pharmazie 1985; 40: 705–709
  • Papahadjopoulos D. Liposomes and their use in biology and medicine. Annals of New York Academy of Sciences 1978; 308: 1–462
  • Papahadjopoulos D., Poste G., Vail W. J., Biedler J. L. Use of lipid vesicles as carriers to introduce actinomycin D into resistant tumor cells. Cancer Research 1976; 36: 2988–2995
  • Patel K. R., Jonah M. M., Rahman Y. E. In vitro uptake and therapeutic application of liposome-encapsulated methotrexate in mouse hepatoma 129. European Journal of Cancer and Clinical Oncology 1982; 18: 833–843
  • Rahman A., White G., More N., Schein P. S. Pharmacological, toxicological, and therapeutic evaluation in mice of Doxorubicin entrapped in cardiolipin liposomes. Cancer Research 1985; 45: 769–803
  • Ritter C., Rutman R. J. Relative enhancement by various liposomes of BCNU effectiveness against L 1210 leukemia in vivo. Research Communications in Chemical Pathology and Pharmacology 1980; 30: 123–131
  • Ryman B. E., Tyrrell D. A. Liposomes-Bags of Potential. Essays in Biochemistry 1980; 16: 49–98
  • Schseier H., Raeder-Schikorr M. Liposomen-ein neuartiger Arzneistofftrager. Pharmazie in unserer Zeit 1982; 11: 97–108
  • Singleton W. S., Grey M. S., Broen H. L. Chromatographically homogeneous lecithin from egg phospholipids. Journal of the American Oil Chemical Society 1965; 42: 53–56
  • Liposomes and Immunobiology, B. H. Tom, N. R. Six. Elsevier/North-Holland, Amsterdam 1980
  • Weinstein J. N., Leserman L. D. Liposomes as drug carriers in cancer chemotherapy. Pharmacy and Therapy 1984; 24: 207–233

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