42
Views
12
CrossRef citations to date
0
Altmetric
Research Article

Evaluation of polyalkylcyanoacrylate nanoparticles as a potential drug carrier: preparation, morphological characterization and loading capacity

, , , , &
Pages 353-366 | Received 26 May 1992, Accepted 05 Jun 1992, Published online: 27 Sep 2008

References

  • Al Khouri N., Fessi H., Roblot-Treupel L., Devissaguet J. P., Puisieux F. Etude et mise au point d'un procédé original de préparation de nanocapsules de polyalkylcyanoacrylates par polymérisation interfaciale. Pharmaceutica Acta Helvetiae 1986b; 61: 274–281
  • Al Khouri N., Roblot-Treupel L., Fessi H., Devissaguet J. P., Puisieux F. Development of a new process for the manufacture of polyisobutylcyanoacrylate nanocapsules. International Journal of Pharmaceutics 1986a; 2(8)125–132
  • Birrenbach G., Speiser P. P. Polymerized micelles and their use as adjuvants in immunology. Journal of Pharmaceutical Sciences 1976; 65: 1763–1766
  • Brown L., Langer R. Transdermal delivery of drugs. Annual Revue of Medicine 1988; 39: 221–229
  • Couvreur P. Poly(alkyl cyanoacrylate)s as colloidal drug carrier. CRC Critical Reviews in Therapeutic Drug Carrier Systems 1988; 5(1)1–20
  • Couvreur P., Kante B., Grislain L., Roland M., Speiser P. Toxicity of polyalkylcyanoacrylate nanoparticles II: Doxorubicin-loaded nanoparticles. Journal of Pharmaceutical Science 1982b; 71: 790–792
  • Couvreur P., Kante B., Roland M., Guiot P., Baudhuin P., Speiser P. Polycyanoacrylate nanocapsules as potential lysosomotropic carriers: preparation, morphological and sorptive properties. Journal of Pharmacy and Pharmacology 1979; 31: 331–332
  • Couvreur P., Lenaerts V., Leyh D., Guiot P., Roland M. Design of biodegradable polyalkylcyanoacrylate nanoparticles as a drug carrier. Microspheres and Drug Therapy. Pharmaceutical, Immunological and Medical Aspects, S. S. Davis, L. Ilium, J. G. McVie, E. Tomlinson. Elsevier, Amsterdam 1984b; 103–115
  • Couvreur P., Roland M., Speiser P. Submicroscopic particles and pharmaceutical composition containing them. US Patent 4,329,332, 1982a
  • Couvreur P., Roland M., Speiser P. Study on the pharmacokinetics and tissue distribution of alkyl polycyanoacrylate nanoparticles. US Patent 4,489,055, 1984a
  • Couvreur P., Vauthier C. Polyalkylcyanoacrylate nanoparticles as drug carrier: present state and perspectives. Journal of Controlled Release 1991; 17: 187–198
  • Crankshaw D. P., Edwards N. E., Blackman G. L., Boyd M. D., Chan H. N. J., Morgan D. J. Evaluation of infusion regimens for thiopentone as a primary anesthetic agent. European Journal of Clinical Pharmacology 1985; 28: 543–552
  • Doglas S. J., Davis S. S., Illum L. Biodistribution of poly(buthyl 2-cyanoacrylate) nanoparticles in rabbits. International Journal of Pharmaceutics 1986; 34: 145–152
  • El-Egakey M. A., Bentele V., Kreuter J. Molecular weights of polycyanoacrylate nanoparticles. International Journal of Pharmaceutics 1983; 13: 349–352
  • Eromosele I. C., Pepper D. C., Ryan B. Water effects on the zwitterionic polymerization of cyanoacrylate. Macromolecular Chemistry 1989; 190: 1613–1622
  • Ganderton D. Current innovation in drug delivery. Drug Design and Delivery 1987; 2: 1–7
  • Grislain L., Couvreur P., Lenaerts V., Roland M., Deprez-Decampaneere D., Speiser P. Pharmacokinetics and distribution of a biodegradable drug-carrier. International Journal of Pharmaceutics 1983; 15: 335–345
  • Harmia T., Kreuter J., Speiser P., Boye T., Gurny R., Kubis A. Enhancement of the myotic response of rabbits with pilocarpine-loaded polybutylcyanoacrylate nanoparticles. International Journal of Pharmaceutics 1986; 33: 187–193
  • Kreuter J., Mills S. N., Davis S. S., Wilson C. G. Polybutylcyanoacrylate nanoparticles for the delivery of [75SE]norcholestenol. International Journal of Pharmaceutics 1983; 16: 105–113
  • Kreuter J., Speiser P. P. in vitro studies of poly(methyl methacrylate) adjuvants. Journal of Pharmaceutical Sciences 1976; 65: 1624–1627
  • Noonan P. K., Benet L. Z. Variable glyceryl dinitrate formation as a function of route of nitroglycerin administration. Clinical Pharmacology and Therapeutics 1987; 42: 273–277
  • Peretti E., Karlaganis G., Lauterburg B. H. Increase urinary excretion of toxic hydrazino metabolites of isoniazid by slow acetylators. Effect of a slow-release preparation of isoniazid. European Journal of Clinical Pharmacology 1987; 33: 283–286
  • Provencher S. W. Inverse problem in polymer characterization: direct analysis of polydispersity with photon correlation spectroscopy. Macromolecular Chemistry 1979; 180: 201–209
  • Provencher S. W. A constrained regularization method for inverting data represented by linear algebraic or integral equations. Computer Physics Communications 1982; 27: 213–227
  • Stanley T. H. New routes of administration and new delivery systems of anesthetics. Anesthesiology 1988; 68: 665–668

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.