62
Views
13
CrossRef citations to date
0
Altmetric
Research Article

Production of water-containing polymer microcapsules by the complex emulsion/solvent evaporation technique. Effect of process variables on the microcapsule size distribution

&
Pages 627-638 | Received 16 Sep 1994, Accepted 10 Nov 1994, Published online: 27 Sep 2008

References

  • Alex R., Bodmeier R. Encapsulation of water-soluble drugs by a modified solvent evaporation method. I. Effect of process and formulation variables on drug entrapment. Journal of Microencapsulation 1990; 7(3)347–355
  • Cavalier M., Benoit J. P., Thies C. The formation and characterization of hydrocortisone-loaded poly ((±)-lactide) microspheres. Journal of Pharmacy and Pharmacology 1985; 38: 249–253
  • Chatzi E. G., Gavrielides A. D., Kiparissides C. Generalized model for prediction of the steady-state drop size distributions in batch stirred vessels. Industrial and Engineering Chemical Research 1989; 28(11)1704–1711
  • Chatzi E. G., Boutris J., Kiparissides C. On-line monitoring of dfop size distributions in agitated vessels. 2. Effect of stabilizer concentration. Industrial and Engineering Chemical Research 1991; 30(6)1307–1313
  • Florence A. T., Whitehill D. Some features of breakdown in water-in-oil-in-water multiple emulsions. Journal of Colloid and Interface Science 1981; 79(1)243–256, Fransaer, J., Celis, J. P., and Roos, J. R., 1989, Metal-liquid composite coatings. Metal Finishing, 87 (6), 107–109
  • Frenkel M., Shwartz R., Garti N. Multiple emulsions. I. Stability: Inversion, apparent and weighted HLB. Journal of Colloid and Interface Science 1982; 94(1)174–178
  • Hashida M., Yoshioka T., Muranishi S., Sezaki H. Dosage form characteristics of microsphere-in-oil emulsions. I: Stability and drug release. Chemical and Pharmaceutical Bulletin 1980; 28(4)1009–1015
  • Jalil R., Nixon J. R. Microencapsulation using poly(L-lactic acid) II, Preparative variables affecting microcapsule properties. Journal of Microencapsulation 1990a; 7(1)25–39
  • Jalil R., Nixon J. R. Biodegradable poly(lactic acid) and poly(lactide-coglycolide) microcapsules: problems associated with preparative techniques and release properties, (Review). Journal of Microencapsulation 1990b; 7(3)297–325
  • Juni K., Ogata J., Nakano M., Ichihara T., Mori K., Akagi M. Preparation and evaluation in vitro and in vivo of polylactic acid microspheres containing doxorubicin. Chemical and Pharmaceutical Bulletin 1985; 33(1)313–318
  • Mac A., Negi D., Friend D. Preparation and characterization of poly(styrene) microcapsules containing corrosion inhibitors. Journal of Microencapsulation 1989; 6(3)361–367
  • Matsumoto S., Inoue T., Kohda M., Ikura K. Water permeability of oil layers in w/o/w emulsions under osmotic pressure gradients. Journal of Colloid and Interface Science 1980; 77(2)555–563
  • Nianxi Y., Mingzu Z., Peihong N. A study of the stability of w/o/w multiple emulsions. Journal of Microencapsulation 1992; 9(2)143–151
  • Nozawa Y., Hikashide F., Kanamoto T. Drug release from and properties of polystyrene microcapsules (Notes). Journal of Applied Polymer Science 1976; 20: 3197–3200
  • Shinar R. On the behaviour of liquid dispersions in mixing vessels. Journal oj Fluid Mechanics 1961; 10: 259–275
  • Shinar R., Church J. M. Predicting particle size in agitated dispersions. Industrial and Engineering Chemistry 1960; 52(3)253–256
  • Takenaka H., Kawashima Y., Chikamatsu Y., Yutaka A. Reactivity and stability of microencapsulated placental alkaline phosphatase. Chemical and Pharmaceutical Bulletin 1982; 30(2)695–701
  • Tan H. S., Ng T. H., Mahabadi H. K. Interfacial polymerization encapsulation of a viscous pigment mix: encapsulation conditions and particle size distribution. Journal of Microencapsulation 1991; 8(4)525–536
  • Tateno A., Shiba B., Kondo T. Electrophoretic behavior of ethyl cellulose and polystyrene microcapsules containing aqueous solutions of polyelectrolytes. Emulsions, and Disperszons, P. Becher, M. Y. Yudenfreund. Marcel Dekker Inc., New York 1978; 279–288
  • Watts P. J., Davies M. C., Melia C. D. Microencapsulation using emulsification/solvent evaporation: An overview of techniques and applications. Critical Reviews in Therapeutic Drug Carrier Systems 1990; 7(Issue 3)235–259

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.