Protein delivery from poly(lactic-co-glycolic acid) biodegradable microspheres: Release kinetics and stability issues

References

• Alonso M. J., Cohen S., Park T. G., Gupta R. K., Siber G. R., Langer R. Determinants of release rate of tetanus vaccine from polyester microspheres. Pharm. Res. 1993; 10: 945–953
   PubMed Web of Science ®Google Scholar
• Burke P. A. Determination of internal pH in PLGA microspheres using 31P NMR spectroscopy. Proc. Intl. Symp. Control. Rel. Bioact. Mater. 1996; 23: 133–134
   Google Scholar
• Cleland J. L., Langer R. Formulation and delivery of proteins and peptides: design and development strategies. Formulation and Delivery of Proteins and Peptides, J. L. Cleland, R. Langer. ACS symposium series 567, ACS, Washington, DC 1994; 1–21
   Google Scholar
• Cohen S., Yoshioka T., Lucarelli M., Hwang L. H., LanCer R. Controlled delivery systems for proteins based on poly(lactic/glycolic acid) microspheres. Pharm. Res. 1991; 8: 713–720
   PubMed Web of Science ®Google Scholar
• Crotts G., Park T. G. Preparation of porous and nonporous biodegradable polymeric hollow microspheres. J. Controlled Release 1995; 35: 91–105
   Web of Science ®Google Scholar
• Crotts G., Park T. G. Stability and release of bovine serum albumin encapsulated within poly(D,L,-lactide-co-glycolide) microparticles. J. Controlled Release 1997; 44: 123–134
   Web of Science ®Google Scholar
• Crotts G., Sah H., Park T. G. Adsorption determines in-vitro protein release rate from biodegradable microspheres: quantitative analysis of surface area during degradation. J. Controlled Release 1997; 47: 101–111
   Web of Science ®Google Scholar
• Hora M. S., Rana R. K., Nunberg J. H., Tice T. R., Gilley R. M., Hudson M. E. Release of human serum albumin from poly(lactide-co-glycolide) micro-spheres. Pharm. Res. 1990; 7: 1190–1194
   PubMed Web of Science ®Google Scholar
• Hutchinson F. G., Furr B. J. A. Biodegradable polymer systems for the sustained release of polypeptides. J. Controlled Release 1990; 13: 279–294
   Web of Science ®Google Scholar
• Jeffrey H., Davis S. S., O'HaCan D. T. The preparation and characterization of poly(lactide-co-glycolide) microparticles. II. Protein entrapment by water-in-oil-in-water emulsion solvent evaporation. Pharm. Res. 1993; 10: 362–368
   PubMed Web of Science ®Google Scholar
• Johnson O. L., Cleland J. L., Lee H. J., Charnis M., Duenas E., Jaworowicz W., Shepard D., Shahzamani A., Jones A. J. S., Putney S. D. A month-long effect from a single injection of microencapsulated human growth hormone. Nature Medicine 1996; 2: 795–799
   PubMed Web of Science ®Google Scholar
• Langer R. New Methods of drug delivery. Science 1990; 249: 1527–1533
   PubMed Web of Science ®Google Scholar
• Lewis D. D. Controlled release of bioactive agents from lactide/glycolide polymer. Biodegradable Polymer as Drug Delivery Systems, M. Chasin, R. Langer. Marcel Dekker, New York 1990; 1–41
   Google Scholar
• Liu W. R., Langer R., Klibanov A. M. Moisture-induced aggregation of lyophilized proteins in the solid state. Biotechnology and Bioengineering 1991; 37: 177–184
   PubMed Web of Science ®Google Scholar
• Lu W., Park T. G. Protein release from poly(lactic-co-glycolic acid) microspheres: protein stability problems. PDA J. of Pharm. Sci. and Technol. 1994; 49: 13–19
   Google Scholar
• Lu W., Park T. G. In vitro release profiles of eristostatin from biodegradable polymeric microspheres: protein aggregation problem. Biotechnol. Prog. 1995; 11: 224–227
   PubMedGoogle Scholar
• Maulding H. Prolonged delivery of peptides by microcapsules. J. Controlled Release 1987; 6: 167–176
   Google Scholar
• Mehta R. C., Jeyanthi R., Calis S., Thanoo B. C., Burton K. W., DeLuca P. P. Biodegradable microspheres as depot system for parenteral delivery of peptide drugs. J. Controlled Release 1994; 29: 375–384
   Web of Science ®Google Scholar
• Ogawa Y., Okada H., Yamamoto M., Shinamoto T. In vivo release profiles of leuprolide acetate from microcapsules prepared with polylactic acids or copoly(lactic/glycolic) acid and in vivo degradation of these polymers. Chem. Pharm. Bull. 1988a; 36: 2576–2588
   PubMed Web of Science ®Google Scholar
• Ogawa Y., Yamamoto M., Okada H., Yashiki T., Shimamoto T. A new technique to efficiently entrap leuprolide acetate into microcapsules of polylactic acid or copoly(lactic/glycolic) acid. Chem. Pharm. Bull. 1988b; 36: 1095–1103
   PubMed Web of Science ®Google Scholar
• Ogawa Y., Yamamoto M., Takada S., Okada H., Shimamoto T. Controlled-release of leuprolide acetate from polylactic acid or copoly(lactic/glycolic) acid microcapsules: influence of molecular weight and copolymer ratio of polymer. Chem. Pharm. Bull. 1988c; 36: 1502–1507
   PubMed Web of Science ®Google Scholar
• Park T. G. Degradation of poly(D,L-lactic acid) microspheres: effect of molecular weight. J. Controlled Release 1994; 30: 161–173
   Web of Science ®Google Scholar
• Park T. G., Lee H. Y., Nam Y. S. A new preparation method for protein loaded poly(a,i.-lactic-co-glycolic acid) microspheres and protein release mechanism study. Journal of Controlled Release 1998, In press
   Google Scholar
• Park T. G., Lu W., Crotts G. Importance of in vitro experimental conditions on protein release kinetics, stability, and polymer degradation in protein encapsulated poly(D,L-lactic-co-glycolic acid) microspheres. J. Controlled Release 1995; 33: 221–222
   Google Scholar
• Sah H. A new strategy to determine the actual protein content of poly(lactide-co-glycolide) microspheres. J. Pharm. Sci. 1997; 86: 1315–1318
   PubMed Web of Science ®Google Scholar
• Schwendeman S. P., Cardamone M., Klibanov A., LanCer R., Brandon M. Stability of proteins and their delivery from biodegradable polymer microspheres. Microparticulate Systems for the Delivery of Proteins and Vaccines, S. Cohen, H. Bernstein. Marcel Dekker, New York 1996; 1–49
   Google Scholar
• Shah S. S., Cha Y., Pitt C. G. Poly(glycolic acid-co-DL-lactic acid): diffusion or degradation controlled drug delivery. J. Controlled Release 1992; 18: 261–270
   Web of Science ®Google Scholar
• Yan C., Resau J. H., Jewetson J., West M., Rill W. L., Kende M. Characterization and morphological analysis of protein-loaded poly(lactide-coglycolide) microparticles prepared by water-in-oil-in-water emulsion technique. J. Controlled Release 1994; 32: 231–241
   Web of Science ®Google Scholar