Iodo-2′-deoxyuridine (IUdR) and ¹²⁵IUdR loaded biodegradable microspheres for controlled delivery to the brain

References

• Baranowska-Kortylewicz J., Makrigiorgos G. M., Van Den Abbeele A. D., Berman R. M., Adelstein S. J., Kassis A. I. 5–[123I]Iodo-2-deoxyuridine in the radiotherapy of an early ascites tumor model. International Journal of Radiation Biology and Physics 1991; 21: 1541–1551
   PubMed Web of Science ®Google Scholar
• Benoit J.-P., Marchais H., Rolland H., Velde V. V. Biodegradable microspheres: advances in production technology. Microencapsulation: Methods and Industrial Application, S. Benita. Marcel Dekker, New York 1996; 35–72
   Google Scholar
• Bloomer W. D., Adelstein S. J. 5–125I-Iododeoxyuridine as prototype for radionuclide therapy with Auger emitters. Nature 1977; 215: 620–621
   Google Scholar
• Bodmeier R., McGinity J. W. The preparation and evaluation of drug-containing poly(DL-lactide) microspheres formed by the solvent evaporation method. Pharmaceutical Research 1987; 4: 465–471
   PubMed Web of Science ®Google Scholar
• Brem H., Piantadosi S., Burger P. C., Walker M., Selker R., Vick N. A., Black K., Sisti M., Brem S., Mohr G., Muller P., Morawetz R., Schold S. C. Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. Lancet 1995; 345: 1008–1012
   PubMed Web of Science ®Google Scholar
• Crossan I. M., Whateley T. L. Microspheres of dexamethasone as a biodegradable controlled release drug delivery system. Proceedings of the Controlled Release Society 1994; 21: 185–186
   Google Scholar
• Fallon P. A. Controlled Drug Delivery to the Brain using Biodegradable Polymers. Department of Pharmaceutical Sciences, University of Strathclyde, Glasgow 1996, Ph.D. thesis
   Google Scholar
• Fallon P. A., Whateley T. L. The development and evaluation of poly(lacticco-glycolic acid) implants for sustained delivery of dexamethasone to the brain. Proceedings of the Controlled Release Society 1994; 21: 264–265
   Google Scholar
• Geze A., Venier-Julienne M. C., Daumas-Duport C., Devauchelle P., Benoit J.-P. Modulated release profiles of IUdR from Poly(D,L lactide-co-glycolide) microspheres by addition of Poly(D,L lactide) oligomers. Proceedings of the Controlled Release Society 1997; 24: 993–994
   Google Scholar
• Jalil R., Nixon J. R. Microencapsulation using poly(L-lactic acid) I: Microcapsule properties affected by the preparative technique. Journal of Microencapsulation 1989; 6: 473–484
   PubMed Web of Science ®Google Scholar
• Jalil R., Nixon J. R. Microencapsulation using poly(L-lactic acid) II: Preparative variables affecting microcapsule properties. Journal of Microencapsulation 1990a; 7: 25–39
   PubMed Web of Science ®Google Scholar
• Jalil R., Nixon J. R. Biodegradable poly(lactic acid) and poly(lactic-coglycolide) microcapsules: problems associated with preparative techniques and release properties. Journal of Microencapsulation 1990b; 7: 297–325
   PubMed Web of Science ®Google Scholar
• Kassis A. I., Van Den Abbeele A. D., Wen P. Y. C., Aaronson R. A., Desisto W. C., Lampson L. A., Black P. M. L., Adelstein S. J. Specific uptake of the Auger electron-emitting thymidine analogue 5–[123I/125I]1odo-2-deoxyuridine in rat brain tumours: Diagnostic and therapeutic implications in humans. Cancer Research 1990; 50: 5199–5203
   PubMed Web of Science ®Google Scholar
• Menei P., Boisdron-Celle M., Croue A., Guy G., Benoit J.-P. Effect of stereotaxic implantation of biodegradable 5-flourouracil-loaded microspheres in healthy and C6 glioma-bearing rats. Neurosurgery 1996; 39: 117–123
   PubMed Web of Science ®Google Scholar
• Neshasteh-Riz A., Angerson W. J., Reeves J. R., Smith G., Rampling R., Mairs R. J. Incorporation of iododeoxyuridine in multicellular glioma spheroids: implications for DNA-targeted radiotherapy using Auger electron emitters. British Journal of Cancer 1997; 75: 493–499
   PubMed Web of Science ®Google Scholar
• Neshasteh-Riz, Mairs R. J., Angerson W. J., Stanton P. D., Reeves J. R., Rampling R., Owens J., Wheldon T. E. Differential cytotoxicity of [123I]IUdR, [125I]IUdR and [131I]IUdR to human glioma cells in monolayer or spheroid culture: effect of proliferative heterogeneity and radiation cross-fire. British Journal of Cancer 1998; 77: 385–390
   PubMedGoogle Scholar
• Ogawa Y., Yamamoto M., Okada H., Yashiki T., Schimamoto T. A new technique to efficiently entrap leuprolide acetate into microcapsules of polylactic acid or copoly(lactic/glycolide) acid. Chemical Pharmaeceutical Bulletin 1988; 36: 1095–1103
   PubMed Web of Science ®Google Scholar
• Olivi A., Ewend M. G., Utsuki T., Tyler B., Domb A. J., Brat D. J., Brem H. Interstitial delivery of carboplatin via biodegradable polymers is effective against experimental glioma in the rat. Cancer Chemical Pharmacology 1996; 39: 90–96
   PubMed Web of Science ®Google Scholar
• Sipos E. P., Tyler B., Piantadosi S., Burger P. C., Brem H. Optimizing interstitial delivery of BCNU from controlled release polymers for the treatment of brain tumors. Cancer Chemotherapy Pharmacology 1997; 39: 383–389
   PubMed Web of Science ®Google Scholar
• Spenlehauer G., Vert M., Benoit J.-P., Boddaert A. In vitro and in vivo degradation of Poly(D,L lactide/glycolide) type microspheres made by solvent evaporation method. Biomaterials 1989; 10: 557–563
   PubMed Web of Science ®Google Scholar
• Tsai D. C., Howard S. A., Hogan T. F., Malanga C. J., Kandzari S. J., Ma J. K. H. Preparation and in vitro evaluation of polylactic acid-mitomycin-cmicrocapsules. Journal of Microencapsulation 1986; 3: 181–193
   PubMedGoogle Scholar
• Uchida T., Yoshida K., Goto S. Preparation and characterization of polylactic acid microspheres containing water-soluble dyes using a novel w/o/w emulsion solvent evaporation method. Journal of Microencapsulation 1996; 13: 219–228
   PubMed Web of Science ®Google Scholar
• Whateley T. L. Biodegradable microspheres for controlled drug delivery. Encapsulation and Controlled Release, D. R. Karsa, R. A. Stephenson. Royal Society of Chemistry, London 1993; 52–65
   Google Scholar
• Whateley T. L., Rampling R., Robertson L., Crossan I. M., Fallon P. A., Plumb J. A., Kerr D. J. Biodegradable systems for sustained delivery of drugs to brain-tumors. Journal of Cellular Biochemistry 1995; S19A: 178
   Google Scholar
• Williams J. A., Dillehay L. E., Tabassi K., Sipos E., Fahlman C., Brem H. Implantable biodegradable polymers for IUdR radiosensitization of experimental human malignant glioma. Journal of Neurooncology 1997; 32: 181–192
   PubMedGoogle Scholar