Controlled radio-frequency hyperthermia using an MR scanner and simultaneous monitoring of temperature and therapy response by ¹H, ²³Na and ³¹P magnetic resonance spectroscopy in subcutaneously implanted 9L-gliosarcoma

References

• Pennacchioli E, Fiore M, Gronchi A. Hyperthermia as an adjunctive treatment for soft-tissue sarcoma. Expert Rev Anticancer Ther 2009; 9: 199–210
   PubMed Web of Science ®Google Scholar
• Hildebrandt B, Wust P. The biologic rationale of hyperthermia. Cancer Treat Res 2007; 134: 171–184
   PubMedGoogle Scholar
• Falk MH, Issels RD. Hyperthermia in oncology. Int J Hyperthermia 2001; 17: 1–18
   PubMed Web of Science ®Google Scholar
• Perez CA, Gillespie B, Pajak T, Hornback NB, Enami B, Rubin P. Quality assurance problems in clinical hyperthermia and their impact on therapeutic outcome: A report by the Radiation Therapy Oncology Group. Int J Radiat Oncol Biol Phys 1989; 16: 551–558
   PubMed Web of Science ®Google Scholar
• Bezabeh T, Evelhoch JL, Sloop DJ, Ackerman JJ. Methodology for applied 4 MHz RF hyperthermia concomitant with 31P NMR spectroscopic monitoring of murine tumours. Int J Hyperthermia 2004; 20: 637–645
   PubMed Web of Science ®Google Scholar
• Jayasundar R, Hall LD, Bleehen NM. RF coils for combined MR and hyperthermia studies: II. MR coil as a hyperthermic applicator. Magn Reson Imaging 2001; 19: 117–122
   PubMedGoogle Scholar
• Sreenivasa G, Gellermann J, Rau B, Nadobny J, Schlag P, Deuflhard P, Felix R, Wust P. Clinical use of the hyperthermia treatment planning system HyperPlan to predict effectiveness and toxicity. Int J Radiat Oncol Biol Phys 2003; 55: 407–419
   PubMed Web of Science ®Google Scholar
• Babsky A, Hekmatyar SK, Wehrli S, Nelson D, Bansal N. Effects of temperature on intracellular sodium, pH and cellular energy status in RIF-1 tumor cells. NMR Biomed 2004; 17: 33–42
   PubMedGoogle Scholar
• Babsky A, Hekmatyar SK, Wehrli S, Nelson D, Bansal N. Hyperthermia-induced changes in intracellular sodium, pH and bioenergetic status in perfused RIF-1 tumor cells determined by 23Na and 31P magnetic resonance spectroscopy. Int J Hyperthermia 2005; 21: 141–158
   PubMed Web of Science ®Google Scholar
• Mikkelsen RB, Asher CR. Effects of hyperthermia on the membrane potential and Na+ transport of V79 fibroblasts. J Cell Physiol 1990; 144: 216–221
   PubMedGoogle Scholar
• Skrandies S, Bremer B, Pilatus U, Mayer A, Neuhaus-Steinmetz U, Rensing L. Heat shock- and ethanol-induced ionic changes in C6 rat glioma cells determined by NMR and fluorescence spectroscopy. Brain Res 1997; 746: 220–230
   PubMedGoogle Scholar
• Ng TC, Evanochko WT, Hiramoto RN, Ghanta VK, Lilly MB, Lawson AJ, Corbett TH, Durant JR, Glickson JD. 31P NMR spectroscopy of in vivo tumors. J Magn Reson 1982; 49: 271–286
   Web of Science ®Google Scholar
• Naruse S, Higuchi T, Horikawa Y, Tanaka C, Nakamura K, Hirakawa K. Radiofrequency hyperthermia with successive monitoring of its effects on tumors using NMR spectroscopy. Proc Nat Acad Sci USA 1986; 83: 8343–8347
   PubMed Web of Science ®Google Scholar
• Jayasundar R, Honess D, Hall LD, Bleehen NM. Simultaneous evaluation of the effects of RF hyperthermia on the intra- and extracellular tumor pH. Magn Reson Med 2000; 43: 1–8
   PubMedGoogle Scholar
• Bezabeh T, Evelhoch JL, Thompson P, Sloop DJ, Ackerman JJ. Therapeutic efficacy as predicted by quantitative assessment of murine RIF-1 tumour pH and phosphorous metabolite response during hyperthermia: An in vivo 31P NMR study. Int J Hyperthermia 2004; 20: 335–357
   PubMed Web of Science ®Google Scholar
• Hekmatyar SK, Poptani H, Babsky A, Leeper DB, Bansal N. Non-invasive magnetic resonance thermometry using thulium-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate (TmDOTA−). Int J Hyperthermia 2002; 18: 165–179
   PubMed Web of Science ®Google Scholar
• Hekmatyar SK, Kerkhoff RM, Pakin SK, Hopewell P, Bansal N. Noninvasive thermometry using hyperfine-shifted MR signals from paramagnetic lanthanide complexes. Int J Hyperthermia 2005; 21: 561–574
   PubMed Web of Science ®Google Scholar
• Zuo CS, Mahmood A, Sherry AD. TmDOTA: A sensitive probe for MR thermometry in vivo. J Magn Reson 2001; 151: 101–106
   PubMed Web of Science ®Google Scholar
• Haase A, Frahm J, Hanicke W, Matthaei D. 1H NMR chemical shift selective (CHESS) imaging. Phys Med Biol 1985; 30: 341–344
   PubMed Web of Science ®Google Scholar
• Winter PM, Bansal N. Triple-quantum-filtered 23Na NMR spectroscopy of subcutaneously implanted 9L gliosarcoma in the rat in the presence of TmDOTP5−. J Magn Reson 2001; 152: 70–78
   PubMedGoogle Scholar
• Gillies RJ, Liu Z, Bhujwalla Z. 31P-MRS measurements of extracellular pH of tumors using 3-aminopropylphosphonate. Am J Physiol 1994; 267: C195–203
   PubMed Web of Science ®Google Scholar
• Sapareto SA, Dewey WC. Thermal dose determination in cancer therapy. Int J Radiat Oncol Biol Phys 1984; 10: 787–800
   PubMed Web of Science ®Google Scholar
• Kost GJ. pH standardization for phosphorus-31 magnetic resonance heart spectroscopy at different temperatures. Magn Reson Med 1990; 14: 496–506
   PubMedGoogle Scholar
• Stubbs M, Rodrigues L, Howe FA, Wang J, Jeong KS, Veech RL, Griffiths JR. Metabolic consequences of a reversed pH gradient in rat tumors. Cancer Res 1994; 54: 4011–4016
   PubMedGoogle Scholar
• ICNIRP 1998 Guidelines for limiting exposure to time-varying electric, magnetic and electromagnetic fields (up to 300 GHz). Health Physics 74;4:494–522
   Google Scholar
• Ettinger KV. Radiofrequency power sources for hyperthermia. In: Field SB, Franconi C, editors. Physics and Technology of Hyperthermia: Dordrecht. M. Nijhoff Publishers, 1987. pp 250–293.
   Google Scholar
• Stratton JA. Electromagnetic Theory. McGraw-Hill Book Company, York, PA 1941
   Google Scholar
• Winter PM, Bansal N. TmDOTP5− as a 23Na shift reagent for the subcutaneously implanted 9L gliosarcoma in rats. Magn Reson Med 2001; 45: 436–442
   PubMed Web of Science ®Google Scholar
• Goldsmith M, Damadian R. NMR in cancer. VII. Sodium-23 magnetic resonance of normal and cancerous tissues. Physiol Chem Phys 1975; 7: 263–269
   PubMedGoogle Scholar
• Damadian R, Cope FW. NMR in cancer. V. Electronic diagnosis of cancer by potassium (39K) nuclear magnetic resonance: Spin signatures and T1 beat patterns. Physiol Chem Phys 1974; 6: 309–322
   PubMedGoogle Scholar
• De Poorter J, De Wagter C, De Deene Y, et al. Noninvasive MRI thermometry with the proton resonance frequency (PRF) method: In vivo results in human muscle. Magn Reson Med 1995; 33: 74–81
   PubMed Web of Science ®Google Scholar
• James JR, Gao Y, Miller MA, Babsky A, Bansal N. Absolute temperature MR imaging with thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetramethyl-1,4,7,10-tetraacetic acid (TmDOTMA(-)). Magn Reson Med 2009; 12: 12
   Google Scholar
• Hofer KG, Mivechi NF. Tumor cell sensitivity to hyperthermia as a function of extracellular and intracellular pH. J Natl Cancer Inst 1980; 65: 621–625
   PubMed Web of Science ®Google Scholar
• Song CW. Effect of local hyperthermia on blood flow and microenvironment: A review. Cancer Res 1984; 44: 4721s–4730s
   PubMed Web of Science ®Google Scholar
• Anderson RL, Hahn GM. Differential effects of hyperthermia on the Na+,K+-ATPase of Chinese hamster ovary cells. Radiat Res 1985; 102: 314–323
   PubMed Web of Science ®Google Scholar
• Ruifrok A, Kanon B, Konings A. Na+/K+ ATPase activity in mouse lung fibroblasts and HeLa S3 cells during and after hyperthermia. Int J Hyperthermia 1986; 2: 51–59
   PubMedGoogle Scholar
• Lilly MB, Katholi CR, Ng TC. Direct relationship between high-energy phosphate content and blood flow in thermally treated murine tumors. J Natl Cancer Inst 1985; 75: 885–889
   PubMedGoogle Scholar
• Boyer M, Tannock I. Regulation of intracellular pH in tumor cell lines: Influence of microenvironmental conditions. Cancer Res 1992; 52: 4441–4447
   PubMedGoogle Scholar