361
Views
13
CrossRef citations to date
0
Altmetric
Research Article

Potentiation of metalloenediyne cytotoxicity by hyperthermia

, , &
Pages 435-444 | Received 22 Nov 2010, Accepted 03 Apr 2011, Published online: 14 Jul 2011

References

  • Bergman RG. Reactive 1,4-dehydroaromatics. Acc Chem Research 1973; 6: 25–31
  • Lockhart TP, Bergman RG. Evidence for reactive spine state of 1,4-Dehidrobenzenes. J Am Chem Soc 1981; 103: 4091–4096
  • Lockhart TP, Comita PB, Bergman RG. Kinetic evidence for the formation of discrete 1,4-dehydrobenzene intermediates. Trapping by inter- and intramolecular hydrogen atom transfer and observation of high-temperature CIDNP. J Am Chem Soc 1981; 103: 4082–4090
  • Gredičak M, Jerić I. Enediyne compounds – New promises in anticancer therapy. Acta Pharm 2007; 57: 133–150
  • Bhattacharyya S, Zaleski JM. Metalloendiynes: Advances in the design of thermally and photochemically activated diradical formation for biomedical applications. Curr Topics Med Chem 2004; 4: 1637–1654
  • Grissom JW, Gunawardena GU, Klinberg D, Huang G. The chemistry of enediynes, enyne, allens, and related compounds. Tetrahedron 1996; 52: 6453–6518
  • Wenk HH, Winkler M, Sander W. One century of aryne chemistry. Angew Chem Int Ed 2003; 42: 502–528
  • Jones GB, Wright JM, Hynd G, Wyatt JK, Yancisin M, Brown MA. Protein-degrading enediynes: Library-screening of Bergman cycloaromatization products. Org Lett 2000; 2: 1863–1866
  • Purohit A, Wyatt J, Hynd G, Wright J, El-Shafey A, Swamy N, Ray R, Jones GB. Chemical synthesis of hormone receptor probes: High affinity photoactivated enediyne-estrogens. Tetrahedron Lett 2001; 42: 8579–8582
  • Rawat DS, Zaleski JM. Geometric and electronic control of thermal Bergman cyclization. Synlett 2004; 3: 393–421
  • Ben-Hur E, Elkind MM, Bronk BV. Thermally enhanced radioresponse of cultured Chinese hamster cells: Inhibition of repair of sublethal damage and enhancement of lethal damage. Radiat Res 1974; 58: 38–51
  • Dewey WC, Sapareto SA, Betten DA. Hyperthermic radiosensitization of synchronous Chinese hamster cells: Relationship between lethality and chromosomal aberrations. Radiat Res 1978; 76: 48–59
  • Corry PM, Robinson S, Getz S. Hyperthermic effects on DNA repair mechanisms. Radiology 1977; 123: 475–482
  • Mills MD, Meyn RE. Effects of hyperthermia on DNA repair mechanisms. Radiat Res 1981; 87: 314–328
  • Radford IR. Effects of hyperthermia on the repair of X-ray induced DNA double strand breaks in mouse L cells. Int J Radiat Biol 1983; 5: 551–557
  • Dikomey E, Franzke J. Effect of heat on induction and repair of DNA strand breaks in X-irradiated CHO cells. Int J Radiat Biol 1992; 61: 221–233
  • Wong RSL, Dynlacht J, Cedervall B, Dewey WC. Analysis by pulsed field gel electrophoresis of DNA double-strand breaks induced by heat and/or X-irradiation in bulk and replicating DNA of CHO cells. Int J Radiat Biol 1995; 68: 141–152
  • Xu YJ, Zhen YS, Goldberg IH. C1027 chromophore, a potent new enediyne antitumor antibiotic, induces sequence-specific double-strand DNA cleavage. Biochemistry 1994; 33: 5947–5954
  • Povirk LF. DNA damage and mutagenesis by radiomimetic DNA-cleaving agents: Bleomycin, neocarzinostatin and other enediynes. Mutat Res 1996; 355: 71–89
  • Rawat DS, Zaleski JM. Mg2+-induced thermal enediyne cyclization at ambient temperature. J Am Chem Soc 2001; 123: 9675–9676
  • Hall EJ, Giaccia AJ. Radiobiology for the Radiologist, 6th. Lippincott, Williams and Wilkins, Amsterdam 2006; 166: 546
  • Nicolaou KC, Stabila P, Esmaeli-Azad B, Wrasidlo W, Hiatt A. Cell-specific regulation of apoptosis by designed enediynes. Proc Natl Acad Sci USA 1993; 8: 3142–3146
  • McHugh MM, Gawron LS, Matsui S, Beerman TA. The antitumor enediyne C-1027 alters cell cycle progression and induces chromosomal aberrations and telomere dysfunction. Cancer Research 2005; 65: 5344–5351
  • Abraham RT. Cell cycle check point signaling through the ATM and ATR kinases. Genes Dev 2001; 17: 2177–2196
  • Liu X, Bian C, Ren K, Jin H, Li B, Shao R. Lidamycin induces marked G2 cell cycle arrest in human colon carcinoma HT-29 cell through activation of p38 MAPK pathway. Oncol Rep 2007; 17: 597–603
  • Bulavin DV, Higashimoto Y, Popoff JJ, Gaarde WA, Basrur V, Potapova O, Appella E, Fornace AJ, Jr. Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase. Nature 2001; 411: 102–107
  • Dmitrieva NI, Bulavin DV, Fornace AJ, Jr, Burg MB. Rapid activation of G2/M checkpoint after hypertonic stress in renal inner medullary epithelial (IME) cells is protective and requires p38 kinase. Proc Natl Acad Sci USA 2002; 99: 184–189
  • Hsu YL, Kuo PL, Lin LT, Lin CC. Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest through activation of extracellular-signal regulated kinase and p38 mitogen-activated protein kinase in human breast cancer cells. J Pharmacol Exp Ther 2005; 313: 333–344
  • Wu ZZ, Chien CM, Yang SH, Lin YH, Hu XW, Lu YJ, Wu MJ, Lin SR. Induction of G2/M phase arrest and apoptosis by a novel enediyne derivative, THDA, in chronic myeloid leukemia (K562) cells. Mol Cell Biochem 2006; 292: 99–105
  • Lu YJ, Yang SH, Chien CM, Lin YH, Hu XW, Wu ZZ, Wu MJ, Lin SR. Induction of G2/M phase arrest and apoptosis by a novel enediyne derivative, THDB, in chronic myeloid leukemia (HL-60) cells. Toxicol In Vitro 2007; 1: 90–98
  • Nicolaou KC, Ogawa Y, Zuccarello G, Schweiger EJ, Kumazawa T. Cyclic conjugated enediynes related to calicheamicins and esperamicins: Calculations, synthesis, and properties. J Am Chem Soc 1988; 110: 4866–4868
  • Long BH, Golik J, Forenza S, Ward B, Rehfuss R, Dabrowiak JC, Catino JJ, Musial ST, Brookshire KW, Doyle TW. Esperamicins, a class of potent antitumor antibiotics: Mechanism of action. Proc Natl Acad Sci USA 1989; 86: 2–6
  • Uesawa Y, Sugiura Y. Heat-induced cleavage by esperamicin antitumor antibiotics. Biochemistry 1991; 30: 9242–9246

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.