A new mechanism of thermal sensitivity for rapid drug release and low systemic toxicity in hyperthermia and thermal ablation temperature ranges

References

• McDaniel JR, Dewhirst MW, Chilkoti A. Actively targeting solid tumours with thermoresponsive drug delivery systems that respond to mild hyperthermia. Int J Hyperthermia 2013;29:501–10
   PubMed Web of Science ®Google Scholar
• Shao P, Wang B, Wang Y, Li J, Zhang Y. The application of thermosensitive nanocarriers in controlled drug delivery. J Nanomater 2011;2011:389640
   Google Scholar
• Parodi A, Quattrocchi N, van de Ven AL, Chiappini C, Evangelopoulos M, Martinez JO, et al. Synthetic nanoparticles functionalized with biomimetic leukocyte membranes possess cell-like functions. Nat Nanotechnol 2013;8:61–8
   PubMed Web of Science ®Google Scholar
• Landon CD, Park J-Y, Needham D, Dewhirst MW. Nanoscale drug delivery and hyperthermia: The materials design and preclinical and clinical testing of low temperature-sensitive liposomes used in combination with mild hyperthermia in the treatment of local cancer. Open Nanomed J 2011;3:38–64
   PubMedGoogle Scholar
• Gasselhuber A, Dreher MR, Rattay F, Wood BJ, Haemmerich D. Comparison of conventional chemotherapy, stealth liposomes and temperature-sensitive liposomes in a mathematical model. PLoS One 2012;7:e47453
   PubMed Web of Science ®Google Scholar
• Ta T, Porter TM. Thermosensitive liposomes for localized delivery and triggered release of chemotherapy. J Control Release 2013;169:112–25
   PubMed Web of Science ®Google Scholar
• Needham D, Park J-Y, Wright AM, Tong J. Materials characterization of the low temperature sensitive liposome (LTSL): Effects of the lipid composition (lysolipid and DSPE–PEG2000) on the thermal transition and release of doxorubicin. Faraday Discuss 2013;161:515–34
   PubMed Web of Science ®Google Scholar
• Li L, ten Hagen TL, Hossann M, Süss R, van Rhoon GC, Eggermont AM, et al. Mild hyperthermia triggered doxorubicin release from optimized stealth thermosensitive liposomes improves intratumoral drug delivery and efficacy. J Control Release 2013;168:142–50
   PubMed Web of Science ®Google Scholar
• Gasselhuber A, Dreher MR, Partanen A, Yarmolenko PS, Woods D, Wood BJ, et al. Targeted drug delivery by high intensity focused ultrasound mediated hyperthermia combined with temperature-sensitive liposomes: Computational modelling and preliminary in vivo validation. Int J Hyperthermia 2012;28:337–48
   PubMed Web of Science ®Google Scholar
• Viglianti BL, Dewhirst MW, Boruta RJ, Park J-Y, Landon C, Fontanella AN, et al. Systemic anti-tumour effects of local thermally sensitive liposome therapy. Int J Hyperthermia 2014;30:385–92
   PubMed Web of Science ®Google Scholar
• Chiu GN, Abraham SA, Ickenstein LM, Ng R, Karlsson G, Edwards K, et al. Encapsulation of doxorubicin into thermosensitive liposomes via complexation with the transition metal manganese. J Control Release 2005;104:271–88
   PubMed Web of Science ®Google Scholar
• Banno B, Ickenstein LM, Chiu GN, Bally MB, Thewalt J, Brief E, et al. The functional roles of poly (ethylene glycol)-lipid and lysolipid in the drug retention and release from lysolipid-containing thermosensitive liposomes in vitro and in vivo. J Pharm Sci 2010;99:2295–308
   PubMed Web of Science ®Google Scholar
• Ta T, Convertine AJ, Reyes CR, Stayton PS, Porter TM. Thermosensitive liposomes modified with poly (N-isopropylacrylamide-co-propylacrylic acid) copolymers for triggered release of doxorubicin. Biomacromolecules 2010;11:1915–20
   PubMed Web of Science ®Google Scholar
• de Smet M, Langereis S, den Bosch SV, Grüll H. Temperature-sensitive liposomes for doxorubicin delivery under MRI guidance. J Control Release 2010;143:120–7
   PubMed Web of Science ®Google Scholar
• Ruiz J-C, Burillo G, Bucio E. Interpenetrating thermo and pH stimuli-responsive Polymer networks of PAAc/PNIPAAm grafted onto PP. Macromol Mater Eng 2007;292:1176–88
   Web of Science ®Google Scholar
• Wadajkar AS, Koppolu B, Rahimi M, Nguyen KT. Cytotoxic evaluation of N-isopropylacrylamide monomers and temperature-sensitive poly (N-isopropylacrylamide) nanoparticles. J Nanopart Res 2009;11:1375–82
   Google Scholar
• Yan R, Zhang M, Zhang W, Liu S. Temperature dependent synthesis of micro-and meso-porous silica employing the thermo-responsive polymer of poly (N-isopropylacrylamide) as structure-directing agent. J Sol-Gel Sci Technol 2011;59:315–26
   Google Scholar
• Yang X, Lee HY, Kim JC. Effect of hydrophobic comonomer content on assembling of poly (N-isopropylacrylamide) and thermal properties. J Appl Polym Sci 2011;120:2346–53
   Web of Science ®Google Scholar
• Ward MA, Georgiou TK. Thermoresponsive polymers for biomedical applications. Polymers 2011;3:1215–42
   Web of Science ®Google Scholar
• Scherzinger C, Schwarz A, Bardow A, Leonhard K, Richtering W. Cononsolvency of poly-N-isopropyl acryl amide (PNIPAM): Microgels versus linear chains and macrogels. Curr Opin Colloid Interface Sci 2014;19:84–94
   Web of Science ®Google Scholar
• Deshmukh SA, Kamath G, Suthar KJ, Mancini DC, Sankaranarayanan SK. Non-equilibrium effects evidenced by vibrational spectra during the coil-to-globule transition in poly (N-isopropylacrylamide) subjected to an ultrafast heating–cooling cycle. Soft matter 2014;10:1462–80
   PubMed Web of Science ®Google Scholar
• Li P, Xu R, Wang W, Li X, Xu Z, Yeung KW, et al. Thermosensitive poly (N-isopropylacrylamide-co-glycidyl methacrylate) microgels for controlled drug release. Colloids Surf B Biointerfaces 2013;101:251–5
   PubMed Web of Science ®Google Scholar
• Bekhradnia S, Zhu K, Knudsen K, Sande S, Nyström B. Structure, swelling, and drug release of thermoresponsive poly(amidoamine) dendrimer–poly(N-isopropylacrylamide) hydrogels. J Mater Sci 2014;49:6102–10
   Web of Science ®Google Scholar
• Yang Y, Yan X, Cui Y, He Q, Li D, Wang A, et al. Preparation of polymer-coated mesoporous silica nanoparticles used for cellular imaging by a ‘graft-from’ method. J Mater Chem 2008;18:5731–7
   Web of Science ®Google Scholar
• Chiappetta DA, Sosnik A. Poly (ethylene oxide)-poly (propylene oxide) block copolymer micelles as drug delivery agents: Improved hydrosolubility, stability and bioavailability of drugs. Eur J Pharm Biopharm 2007;66:303–17
   PubMed Web of Science ®Google Scholar
• Chen S, Li Y, Guo C, Wang J, Ma J, Liang X, et al. Temperature-responsive magnetite/PEO-PPO-PEO block copolymer nanoparticles for controlled drug targeting delivery. Langmuir 2007;23:12669–76
   PubMed Web of Science ®Google Scholar
• Yapar EA, Ýnal Ö. Poly (ethylene oxide)–poly (propylene oxide)-based copolymers for transdermal drug delivery: An overview. Trop J Pharm Res 2013;11:855–66
   Web of Science ®Google Scholar
• Jeong B, Gutowska A. Lessons from nature: Stimuli-responsive polymers and their biomedical applications. Trends Biotechnol 2002;20:305–11
   PubMed Web of Science ®Google Scholar
• Ruiz-Hernandez E, Baeza A, Vallet-Regí MA. Smart drug delivery through DNA/magnetic nanoparticle gates. ACS Nano 2011;5:1259–66
   PubMed Web of Science ®Google Scholar
• Derfus AM, von Maltzahn G, Harris TJ, Duza T, Vecchio KS, Ruoslahti E, et al. Remotely triggered release from magnetic nanoparticles. Adv Mater 2007;19:3932–6
   Web of Science ®Google Scholar
• Thomas CR, Ferris DP, Lee J-H, Choi E, Cho MH, Kim ES, et al. Noninvasive remote-controlled release of drug molecules in vitro using magnetic actuation of mechanized nanoparticles. J Am Chem Soc 2010;132:10623–5
   PubMed Web of Science ®Google Scholar
• Kuruppuarachchi M, Savoie H, Lowry A, Alonso C, Boyle RW. Polyacrylamide nanoparticles as a delivery system in photodynamic therapy. Mol Pharm 2011;8:920–31
   PubMed Web of Science ®Google Scholar
• Rossi LM, Shi L, Quina FH, Rosenzweig Z. Stöber synthesis of monodispersed luminescent silica nanoparticles for bioanalytical assays. Langmuir 2005;21:4277–80
   PubMed Web of Science ®Google Scholar
• Shin Y, Lee D, Lee K, Ahn KH, Kim B. Surface properties of silica nanoparticles modified with polymers for polymer nanocomposite applications. J Ind Eng Chem 2008;14:515–19
   Web of Science ®Google Scholar
• Dabbagh A, Abdullah BJJ, Abu Kasim NH, Ramasindarum C. Reusable heat-sensitive phantom for precise estimation of thermal profile in hyperthermia application. Int J Hyperthermia 2013;30:66–74
   PubMed Web of Science ®Google Scholar
• Hon NK, Shaposhnik Z, Diebold ED, Tamanoi F, Jalali B. Tailoring the biodegradability of porous silicon nanoparticles. J Biomed Mater Res A 2012;100:3416–21
   PubMedGoogle Scholar
• Rosenholm JM, Mamaeva V, Sahlgren C, Lindén M. Nanoparticles in targeted cancer therapy: Mesoporous silica nanoparticles entering preclinical development stage. Nanomedicine 2012;7:111–20
   PubMed Web of Science ®Google Scholar
• Caulfield MJ, Qiao GG, Solomon DH. Some aspects of the properties and degradation of polyacrylamides. Chem Rev 2002;102:3067–84
   PubMed Web of Science ®Google Scholar
• Xing Z, Wang C, Yan J, Zhang L, Li L, Zha L. Dual stimuli responsive hollow nanogels with IPN structure for temperature controlling drug loading and pH triggering drug release. Soft Matter 2011;7:7992–7
   Web of Science ®Google Scholar