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British Journal of Neurosurgery Volume 25, 2011 - Issue 2
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Original Article

Difficulties with recruiting into neurosurgical clinical trials: The Surgical Trial in IntraCerebral Haemorrhage II as an example

Matthew Anthony KirkmanBrain Injury Research Group, The University of Manchester, Greater Manchester Neurosciences Centre (GMNC), Salford Royal NHS Foundation Trust, Salford, UKCorrespondence[email protected]
,
Naomi GreenwoodBrain Injury Research Group, The University of Manchester, Greater Manchester Neurosciences Centre (GMNC), Salford Royal NHS Foundation Trust, Salford, UK
,
Navneet Singh
,
Pippa J. Tyrrell
,
Andrew T. King
&
Hiren C. Patel
Pages 231-234 | Received 26 May 2010, Accepted 07 Nov 2010, Published online: 23 Feb 2011

References

  • van Asch CJ, Luitse MJ, Rinkel GJ, van der Tweel I, Algra A, Klijn CJ. Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis. Lancet Neurol 2010;9(2):167–76.
  • Feigin VL, Lawes CM, Bennett DA, Barker-Collo SL, Parag V. Worldwide stroke incidence and early case fatality reported in 56 population-based studies: a systematic review. Lancet Neurol 2009;8(4):355–69.
  • Bamford J, Sandercock P, Dennis M, Burn J, Warlow C. A prospective study of acute cerebrovascular disease in the community: the Oxfordshire Community Stroke Project – 1981–86. 2. Incidence, case fatality rates and overall outcome at one year of cerebral infarction, primary intracerebral and subarachnoid haemorrhage. J Neurol Neurosurg Psychiatry 1990;53:16–22.
  • Keir SL, Wardlaw JM, Warlow CP. Stroke epidemiology studies have underestimated the frequency of intracerebral haemorrhage. A systematic review of imaging in epidemiological studies. J Neurol 2002;249(9):1226–31.
  • Dennis MS. Outcome after brain haemorrhage. Cerebrovasc Dis 2003;16(Suppl 1):9–13.
  • Mendelow AD, Unterberg A. Surgical treatment of intracerebral haemorrhage. Curr Opin Crit Care 2007;13:169–74.
  • Hanggi D, Steiger HJ. Spontaneous intracerebral haemorrhage in adults: a literature overview. Acta Neurochir (Wein) 2008;150(4):371–9.
  • Elliott J, Smith M. The acute management of intracerebral haemorrhage: a clinical review. Anesth Analg 2010;110(5):1419–27.
  • Mendelow AD, Gregson BA, Fernandes HM, Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial. Lancet 2005;365(9457):387–97.
  • Thoma A, Farrokhyar F, McKnight L, Bhandari M. How to optimize patient recruitment. Can J Surg 2010;53(3):205–10.
  • Abraham NS, Young JM, Solomon MJ. A systematic review of reasons for nonentry of eligible patients into surgical randomized controlled trials. Surgery 2006;139:469–83.
  • McCulloch P, Taylor I, Sasako M, Lovett B, Griffin D. Randomised trials in surgery: problems and possible solutions. BMJ 2002;324:1448–51.
  • Solomon MJ, McLeod RS. Should we be performing more randomized controlled trials evaluating surgical operations? Surgery 1995;118:459–67.
  • Kokotailo RA, Hill MD. Coding of stroke and stroke risk factors using International Classification of Diseases, Revisions 9 and 10. Stroke 2005;36:1776–81.
  • Lovelock CE, Molyneux AJ, Rothwell PM, on behalf of the Oxford Vascular Study. Change in incidence and aetiology of intracerebral haemorrhage in Oxfordshire, UK, between 1981 and 2006: a population-based study. Lancet Neurol 2007;6:487–93.
  • National Statistics Online. Available at: http://www.statistics.gov.uk/cci/nugget.asp?ID=6 [Accessed 1 May 2010].
  • STICH. STICH II Trial (STICH 2) intracerebral haemorrhage. Available at: http://www.ncl.ac.uk/stich [Accessed on 1 May 2010].

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