Qualitative grading of disc degeneration by magnetic resonance in the lumbar and cervical spine: lack of correlation with histology in surgical cases

References

• Freemont AJ. The cellular pathobiology of the degenerate intervertebral disc and discogenic back pain. Rheumatology (Oxford) 2009;48:5–10.
   PubMed Web of Science ®Google Scholar
• Adams MA, Dolan P. Intervertebral disc degeneration: evidence for two distinct phenotypes. J Anat 2012;221:497–506.
   PubMed Web of Science ®Google Scholar
• Thompson JP, Pearce RH, Schechter MT, et al. Preliminary evaluation of a scheme for grading the gross morphology of the human intervertebral disc. Spine 1990;15:411–5.
   PubMed Web of Science ®Google Scholar
• Pfirrmann CW, Metzdorf A, Zanetti M, et al. Magnetic resonance classification of lumbar intervertebral disc degeneration. Spine 2001;26:1873–8.
   PubMed Web of Science ®Google Scholar
• Boos N, Weissbach S, Rohrbach H, et al. Classification of age-related changes in lumbar intervertebral discs: 2002 Volvo Award in basic science. Spine 2002;27:2631–44.
   PubMed Web of Science ®Google Scholar
• Sive JI, Baird P, Jeziorsk M, et al. Expression of chondrocyte markers by cells of normal and degenerate intervertebral discs. Mol Pathol 2002;55:91–7.
   PubMedGoogle Scholar
• Miyazaki M, Hong SW, Yoon SH, et al. Kinematic analysis of the relationship between the grade of disc degeneration and motion unit of the cervical spine. Spine 2008;33:187–93.
   PubMed Web of Science ®Google Scholar
• Kettler A, Wilke HJ. Review of existing grading systems for cervical or lumbar disc and facet joint degeneration. Eur Spine J 2006;15:705–18.
   PubMed Web of Science ®Google Scholar
• Kleinst cF, Dvorak J, Mannion AF. Are structural abnormalities on magnetic resonance imaging a contraindication to the successful conservative treatment of chronic nonspecific low back pain? Spine 2006;31:2250–7.
   PubMed Web of Science ®Google Scholar
• Griffith JF, Wang YXJ, Antonio GE, et al. Modified Pfirrmann grading system for lumbar intervertebral disc degeneration. Spine 2007;32:E708–12.
   PubMed Web of Science ®Google Scholar
• Zhang YH, Zhao CQ, Jiang LS, et al. Modic changes: a systematic review of the literature. Eur Spine J 2008;17:1289–99.
   PubMed Web of Science ®Google Scholar
• Hutton MJ, Bayer JH, Powell JM. Modic vertebral body changes: the natural history as assessed by consecutive magnetic resonance imaging. Spine 2011;36:2304–7.
   PubMed Web of Science ®Google Scholar
• Wang Y, Videman T, Niemeläinen R, Battié MC. Quantitative measures of modic changes in lumbar spine magnetic resonance imaging: intra- and inter-rater reliability. Spine 2011;36:1236–43.
   PubMed Web of Science ®Google Scholar
• Albert HB, Manniche C. Modic changes following lumbar disc herniation. Eur Spine J 2007;16:977–82.
   PubMed Web of Science ®Google Scholar
• Modic MT, Steinberg PM, Ross JS, et al. Degenerative disk disease: assessment of changes in vertebral body marrow with MR imaging. Radiology 1988;166:193–9.
   PubMed Web of Science ®Google Scholar
• Christe A, Läubli R, Guzman R, et al. Degeneration of the cervical disc: histology compared with radiography and magnetic resonance imaging. Neuroradiology 2005;47:721–9.
   PubMed Web of Science ®Google Scholar
• Weiler C, Lopez-Ramos M, Mayer HM, et al. Histological analysis of surgical lumbar intervertebral disc tissue provides evidence for an association between disc degeneration and increased body mass index. BMC Res Notes 2011;4:497.
   PubMedGoogle Scholar
• Le Maitre CL, Hoyland JA, Freemont AJ. Interleukin-1 receptor antagonist delivered directly and by gene therapy inhibits matrix degradation in the intact degenerate human intervertebral disc: an in situ zymographic and gene therapy study. Arthritis Res Ther 2007;9:R83.
   PubMed Web of Science ®Google Scholar
• Richardson SM, Purmessur D, Baird P, et al. Degenerate human nucleus pulposus cells promote neurite outgrowth in neural cells. PLoS One 2012;7:e47735.
   PubMed Web of Science ®Google Scholar
• Schiebler ML, Camerino VJ, Fallon MD, et al. In vivo and ex vivo magnetic resonance imaging evaluation of early disc degeneration with histopathologic correlation. Spine 1991;16:635–40.
   PubMed Web of Science ®Google Scholar
• Weidenbaum M, Foster RJ, Best BA, et al. Correlating magnetic resonance imaging with the biochemical content of the normal human intervertebral disc. J Orthop Res 1992;10:552–61.
   PubMed Web of Science ®Google Scholar
• Berlemann U, Gries NC, Moore RJ. The relationship between height, shape and histological changes in early degeneration of the lower lumbar discs. Eur Spine J 1998;7:212–7.
   PubMedGoogle Scholar
• Benneker LM, Heini PF, Anderson SE, et al. Correlation of radiographic and MRI parameters to morphological and biochemical assessment of intervertebral disc degeneration. Eur Spine J 2005;14:27–35.
   PubMed Web of Science ®Google Scholar
• Kokubo Y, Uchida K, Kobayashi S, et al. Herniated and spondylotic intervertebral discs of the human cervical spine: histological and immunohistological findings in 500 en bloc surgical samples. J Neurosurg Spine 2008;9:285–95.
   PubMed Web of Science ®Google Scholar
• Kalson NS, Richardson S, Hoyland JA. Strategies for regeneration of the intervertebral disc. Regen Med 2008;3:717–29.
   PubMed Web of Science ®Google Scholar
• Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics 1977;33:159–74.
   PubMed Web of Science ®Google Scholar
• Majumdar S. Magnetic resonance imaging and spectroscopy of the intervertebral disc. NMR Biomed 2006;19:894–903.
   PubMed Web of Science ®Google Scholar
• Bendix T, Sorensen JS, Henriksson GAC, et al. Lumbar modic changes-a comparison between findings at low- and high-field magnetic resonance imaging. Spine 2012;37:1756–62.
   PubMed Web of Science ®Google Scholar
• Lama P, Le Maitre CL, Dolan P, et al. Do intervertebral discs degenerate before they herniate, or after? Bone Joint J 2013;95B:1127–33.
   Web of Science ®Google Scholar
• Tertti M, Paajanen H, Laato M, et al. Disc degeneration in magnetic resonance imaging. A comparative biochemical, histologic, and radiologic study in cadaver spines. Spine 1991;16:629–34.
   PubMed Web of Science ®Google Scholar
• Urban JPG, Winlove CP. Pathophysiology of the intervertebral disc and the challenges for MRI. J Magn Reson Imaging 2007;25:419–32.
   PubMed Web of Science ®Google Scholar
• Michopoulou S, Costaridou L, Vlychou M, et al. Texture-based quantification of lumbar intervertebral disc degeneration from conventional T2-weighted MRI. Acta Radiol 2011;52:91–8.
   PubMed Web of Science ®Google Scholar
• Mann E, Peterson CK, Hodler J. Degenerative marrow (modic) changes on cervical spine magnetic resonance imaging scans. Spine 2011;36:1081–5.
   PubMed Web of Science ®Google Scholar
• Peterson CK, Humphreys BK, Pringle TC. Prevalence of modic degenerative marrow changes in the cervical spine. J Manipulative Physiol Ther 2007;30:5–10.
   PubMed Web of Science ®Google Scholar
• Mercer S, Bogduk N. The ligaments and annulus fibrosus of human adult cervical intervertebral discs. Spine 1999;24:619–26 (discussion 627–8).
   PubMed Web of Science ®Google Scholar
• Moore RJ. The vertebral endplate: disc degeneration, disc regeneration. Eur Spine J 2006;15:S333–7.
   PubMed Web of Science ®Google Scholar
• Hu ZJ, Zhao FD, Fang XQ, Fan SW. Modic changes, possible causes and promotion to lumbar intervertebral disc degeneration. Med Hypotheses 2009;73:930–2.
   PubMed Web of Science ®Google Scholar
• Matsumoto M, Okada E, Ichihara D, et al. Modic changes in the cervical spine: prospective 10-year follow-up study in asymptomatic subjects. J Bone Joint Surg Br 2012;94:678–83.
   PubMedGoogle Scholar
• Karchevsky M, Schweitzer ME, Carrino JA, et al. Reactive endplate marrow changes: a systematic morphologic and epidemiologic evaluation. Skeletal Radiol 2005;34:125–9.
   PubMed Web of Science ®Google Scholar
• Kuisma M, Karppinen J, Niinimäki J, et al. A three-year follow-up of lumbar spine endplate (Modic) changes. Spine 2006;31:1714–8.
   PubMed Web of Science ®Google Scholar