REFERENCES
- Martini FH. Fundamentals of Anatomy and Physiology. New York: Simon and Schuster; 2006:555–557.
- Dartt DA, Rose PE, Dicker DM, Ronco LV, Hodges RR. α1-adrenergic agonist-stimulated protein secretion in rat exorbital gland acini. Exp Eye Res. 1994;58:423–429.
- Williams RM, Bauce L, Lea RW, Singh J, Sharkey KA. Secretion and serotonin release in the isolated rat lacrimal gland: The effects of substance P and calcitonin gene-related peptide. J Auton Nerv Syst. 1996;61:37–42.
- Dartt DA, Shulman M, Gray KL, Rossi SR, Matkin C, Gilbard JP. Stimulation of rabbit lacrimal gland secretion with biologically active peptides. Am J Physiol. 1988;254:G300–306.
- Drake RL, Vogl W, Mitchell AWM. Gray’s Anatomy for Students. Edinburgh: Churchill Livingstone, Elsevier; 2005:836.
- Stern ME, Gao J, Siemasko KF, Beuerman RW, Pflugfelder SC. The role of the lacrimal functional unit in the pathophysiology of dry eye. Exp Eye Res. 2004;78:409–416.
- Zimmet P, Alberti KGMM, Shaw J. Global and societal implications of the diabetes epidemic. Nature. 2001;414:782–787.
- Rahimi R, Nikfar S, Larijan B, Abdollahi M. A review on the role of antioxidants in the management of diabetes and its complications. Biomed Pharmacother. 2005;59:365–373.
- Moss SE, Klein R, Klein BE. Prevalence of and risk factors for dry eye syndrome. Arch Ophthalmol. 2000;118:1264–1268.
- Ceriello A. New insights on oxidative stress and diabetic complications may lead to a “causal” antioxidant therapy. Diabetes Care. 2003;26:1589–1596.
- Changrani NR, Chonkar A, Adeghate E, Singh J. Effects of streptozotocin-induced type 1 diabetes mellitus on total protein concentrations and cation contents in the isolated pancreas, parotid, submandibular, and lacrimal glands of rats. Ann NY Acad Sci. 2006;1084:503–519.
- Karnowsky MJ. A formaldehyde-glutaraldehyde fixative of light osmolarity for the use in electron microscopy. J Cell Biol. 1965;27:137A.
- Singh J, Adeghate E, Burrows S, Howarth FC, Donáth T. Protein secretion and the identification of neurotransmitters in the isolated pig lacrimal gland. Adv Exp Med Biol. 1994;350:57–60.
- Bradford MM. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein dye binding. Analyt Biochem. 1973;72:248–254.
- Herzog V, Fahimi HD. A new and sensitive colorimetric assay of peroxidase using 3′,3′- diaminobenzidine as hydrogen as a donor. Anal Biochem. 1973;5:554–562.
- Draper CE, Adeghate EA, Singh J, Pallot DJ. Evidence to suggest morphological and physiological alteration of lacrimal gland acini with ageing. Exp Eye Res. 1999;68:265–276.
- Bromberg BB, Welch MH. Lacrimal protein secretion: Comparison of young and aged rats. Exp Eye Res. 1985;40:313–320.
- Bracken NK, Woodall AJ, Howarth FC, Singh J. Voltage-dependence of contraction in streptozotocin-induced diabetic myocytes. Mol Cell Biochem. 2004;261:235–243.
- Alves M, Calegari VC, Cunha DA, Saad MJ, Velloso LA, Rocha EM. Increased expression of advanced glycation end-products and their receptor, and activation of nuclear factor kappa-B in lacrimal glands of diabetic rats. Diabetologia. 2005;48:2675–2681.
- West E, Simon OR, Morrison EY. Streptozotocin alters pancreatic beta-cell responsiveness to glucose within six hours of injection into rats. West Indian Med J. 1996;45:60–62.
- Walcott B, Birzgalis A, Moore LC, Brink PR. Fluid secretion and the Na+-K+2-Cl− co-transporter in mouse exorbital lacrimal gland. Am J Physiol Cell Physiol. 2005;289:860–867.
- Goebbels M. Tear secretion and tear film function in insulin dependent diabetics. Br J Ophthalmol. 2000;84:19–21.
- Herzog V, Fahimi HD. Intracellular distinction between peroxidase and catalase in exocrine cells of rat lacrimal gland: A biochemical and cytochemical study. Histochemistry. 1976;46:273–286.
- Walcott B. The lacrimal gland and its veil of tears. News Physiol Sci. 1998;13:97–103.
- Singh J, Adeghate E, Salido GM, Pariente JA, Juma LMO. Interaction between pancreatic hormones with cholecystokinin-octapeptide-evoked responses in the isolated pancreas or normal and diabetic rats. Exp Physiol. 1999;84:299–318.
- Patel R, Shervington A, Pariente JA, Martinez-Burgos MA, Salido GM, Adeghate E, Singh J. Mechanism of exocrine pancreatic insufficiency in streptozotocin-induced type 1 diabetes mellitus. Ann NY Acad Sci. 2006;1084:71–88.
- Jorge AG, Módulo CM, Dias AC, Braz AM, Filho RB, Jordão Jr AA, de Paula JS, Rocha EM. Aspirin prevents diabetic oxidative changes in rat lacrimal gland structure and function. Endocrine. 2009;35:189–197.
- Draper CE, Singh J, Adeghate E. Effects of age on morphology, protein synthesis, and secretagogue-evoked secretory responses in the rat lacrimal gland. Mol Cell Biochem. 2003;248:7–16.
- Kaysen GA. Diabetes, a cause of progressive sarcopenia in dialysis patients? Kidney Int. 2005;68:2396–2397.
- Madia F, Liberati V, de Feo G, Marcozzi G. Variations of lacrimal fluid peroxidase activity in female and male rats. Ophthalmic Res. 2001;33:176–179.
- Marcozzi G, Liberati V, Madia F, Pizzinga A, De Feo G. Effect of hormone replacement therapy on lacrimal fluid peroxidase activity in woman. Maturitas. 2003;45:225–229.
- Kumar P, Clark M. Neurological disease. In: Clinical Medicine. Chapter 20. London: W. B. Saunders; 2005:1123–1224.