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Original Article

Adenosine A2 Receptor Presence and Synergy with Cholinergic Stimulation in Rabbit Lacrimal Gland

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Pages 466-474 | Received 08 Jul 2009, Accepted 23 Dec 2009, Published online: 14 May 2010

REFERENCES

  • Hodges RR, Dartt DA. Regulatory pathways in lacrimal gland epithelium. Int Rev Cytol. 2003;231:129–196.
  • Dartt DA. Dysfunctional neural regulation of lacrimal gland secretion and its role in the pathogenesis of dry eye syndromes. Ocul Surf. 2004;2:76–91.
  • Mauduit P, Jammes H, Rossignol B. M3 muscarinic acetylcholine receptor coupling to PLC in rat exorbital lacrimal acinar cells. Am J Physiol. 1993;264:C1550–C1560.
  • Nakamura M, Tada Y, Akaishi T, Nakata K. M3 muscarinic receptor mediates regulation of protein secretion in rabbit lacrimal gland. Curr Eye Res. 1997;16:614–619.
  • Hodges RR, Zoukhri D, Sergheraert C, Zieske JD, Dartt DA. Identification of vasoactive intestinal peptide receptor subtypes in the lacrimal gland and their signal-transducing components. Invest Ophthalmol Vis Sci. 1997;38:610–619.
  • Edman MC, Andersson SV, Delbro D, Gierow JP. Functional expression of the adenosine A1 receptor in rabbit lacrimal gland. Exp Eye Res. 2008;86:110–117.
  • Benarroch EE. Adenosine and its receptors: multiple modulatory functions and potential therapeutic targets for neurologic disease. Neurology. 2008;70:231–236.
  • Kanatsuka H, Lamping KG, Eastham CL, Dellsperger KC, Marcus ML. Comparison of the effects of increased myocardial oxygen consumption and adenosine on the coronary microvascular resistance. Circ Res. 1989;65:1296–1305.
  • Cushley MJ, Tattersfield AE, Holgate ST. Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects. Br J Clin Pharmacol. 1983;15:161–165.
  • Dunwiddie TV, Masino SA. The role and regulation of adenosine in the central nervous system. Annu Rev Neurosci. 2001;24:31–55.
  • Bouma MG, van den Wildenberg FA, Buurman WA. Adenosine inhibits cytokine release and expression of adhesion molecules by activated human endothelial cells. Am J Physiol. 1996;270:C522–C529.
  • Mayne M, Fotheringham J, Yan HJ et al. Adenosine A2A receptor activation reduces proinflammatory events and decreases cell death following intracerebral hemorrhage. Ann Neurol. 2001;49:727–735.
  • Haskó G, Cronstein BN. Adenosine: an endogenous regulator of innate immunity. Trends Immunol 2004;25:33–39.
  • Dartt DA, Baker AK, Vaillant C, Rose PE. Vasoactive intestinal polypeptide stimulation of protein secretion from rat lacrimal gland acini. Am J Physiol.. 1984;247:G502–G509.
  • Andersson SV, Edman MC, Bekmezian A et al. Characterization of beta-hexosaminidase secretion in rabbit lacrimal gland. Exp Eye Res. 2006;83:1081–1088.
  • Rismondo V, Gierow JP, Lambert RW et al. Rabbit lacrimal acinar cells in primary culture: morphology and acute responses to cholinergic stimulation. Invest Ophthalmol Vis Sci. 1994;35:1176–1183.
  • Andersson SV, Sjögren EC, Magnusson C, Gierow JP. Sequencing, expression, and enzymatic characterization of beta-hexosaminidase in rabbit lacrimal gland and primary cultured acinar cells. Glycobiology. 2005;15:211–220.
  • Selvam S, Thomas PB, Gukasyan HJ et al. Transepithelial bioelectrical properties of rabbit acinar cell monolayers on polyester membrane scaffolds. Am J Physiol, Cell Physiol. 2007;293:C1412–C1419.
  • Xie J, Chiang L, Contreras J et al. Novel fiber-dependent entry mechanism for adenovirus serotype 5 in lacrimal acini. J Virol. 2006;80:11833–11851.
  • Xie J, Marchelletta RR, Thomas PB et al. Transduced viral IL-10 is exocytosed from lacrimal acinar secretory vesicles in a myosin-dependent manner in response to carbachol. Exp Eye Res. 2009;88:467–478.
  • Brand F, Klutz AM, Jacobson KA, Fredholm BB, Schulte G. Adenosine A(2A) receptor dynamics studied with the novel fluorescent agonist Alexa488-APEC. Eur J Pharmacol. 2008;590:36–42.
  • Gierow JP, Yang T, Bekmezian A et al. Na-K-ATPase in lacrimal gland acinar cell endosomal system: correcting a case of mistaken identity. Am J Physiol. 1996;271:C1685–C1698.
  • Bradley ME, Peters CL, Lambert RW, Yiu SC, Mircheff AK. Subcellular distribution of muscarinic acetylcholine receptors in rat exorbital lacrimal gland. Invest Ophthalmol Vis Sci. 1990;31:977–986.
  • Dartt DA, Baker AK, Rose PE et al. Role of cyclic AMP and Ca2+ in potentiation of rat lacrimal gland protein secretion. Invest Ophthalmol Vis Sci. 1988;29:1732–1738.
  • Funaki C, Hodges RR, Dartt DA. Role of cAMP inhibition of p44/p42 mitogen-activated protein kinase in potentiation of protein secretion in rat lacrimal gland. Am J Physiol, Cell Physiol. 2007;293:C1551–C1560.
  • Schulte G, Fredholm BB. The G(s)-coupled adenosine A(2B) receptor recruits divergent pathways to regulate ERK1/2 and p38. Exp Cell Res. 2003;290:168–176.
  • Kvanta A, Seregard S, Sejersen S, Kull B, Fredholm BB. Localization of adenosine receptor messenger RNAs in the rat eye. Exp Eye Res. 1997;65:595–602.
  • Christofi FL, Zhang H, Yu JG et al. Differential gene expression of adenosine A1, A2a, A2b, and A3 receptors in the human enteric nervous system. J Comp Neurol. 2001;439:46–64.
  • Leal S, Sá C, Gonçalves J, Fresco P, Diniz C. Immunohistochemical characterization of adenosine receptors in rat aorta and tail arteries. Microsc Res Tech. 2008;71:703–709.
  • Novak I, Hede SE, Hansen MR. Adenosine receptors in rat and human pancreatic ducts stimulate chloride transport. Pflugers Arch. 2008;456:437–447.
  • Fornai M, Antonioli L, Colucci R et al. A1 and A2a receptors mediate inhibitory effects of adenosine on the motor activity of human colon. Neurogastroenterol Motil. 2009;21:451–466.
  • Chuaychoo B, Lee MG, Kollarik M, Pullmann R Jr, Undem BJ. Evidence for both adenosine A1 and A2A receptors activating single vagal sensory C-fibres in guinea pig lungs. J Physiol (Lond). 2006;575:481–490.
  • Gerwins P, Fredholm BB. ATP and its metabolite adenosine act synergistically to mobilize intracellular calcium via the formation of inositol 1,4,5-trisphosphate in a smooth muscle cell line. J Biol Chem. 1992;267:16081–16087.
  • Iredale PA, Alexander SP, Hill SJ. Coupling of a transfected human brain A1 adenosine receptor in CHO-K1 cells to calcium mobilisation via a pertussis toxin-sensitive mechanism. Br J Pharmacol. 1994;111:1252–1256.
  • Dickenson JM, Hill SJ. Involvement of G-protein betagamma subunits in coupling the adenosine A1 receptor to phospholipase C in transfected CHO cells. Eur J Pharmacol. 1998;355:85–93.
  • Carlsson SK, Edman MC, Hamm-Alvarez S, Gierow JP: Calcium and cyclic AMP alterations in purinergic regulation of rabbit lacrimal gland acinar cell secretion. 5th International Conference on the Tear Film and Ocular Surface: basic science and clinical relevance, Taormina, September 5–8, 2007. (Abstract)
  • Tang WJ, Gilman AG. Type-specific regulation of adenylyl cyclase by G protein beta gamma subunits. Science. 1991;254:1500–1503.
  • Johnson ME, Murphy PJ. Changes in the tear film and ocular surface from dry eye syndrome. Prog Retin Eye Res. 2004;23:449–474.

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