Mediators and Mechanisms of Herpes Simplex Virus Entry into Ocular Cells

REFERENCES

• Liesegang TJ. Herpes simplex virus epidemiology and ocular importance. Cornea 2001;20:1–13.
   PubMed Web of Science ®Google Scholar
• Liesegang TJ, Melton LJ 3rd, Daly PJ, Ilstrup DM. Epidemiology of ocular herpes simplex. Incidence in Rochester, Minn, 1950 through 1982. Arch Ophthalmol 1989;107:1155–1159.
   PubMed Web of Science ®Google Scholar
• Lairson DR, Begley CE, Reynolds TF, Wilhelmus KR. Prevention of herpes simplex virus eye disease: A cost-effectiveness analysis. Arch Ophthalmol 2003;121:108–112.
   PubMedGoogle Scholar
• Hodge WG, Margolis TP. Herpes simplex virus keratitis among patients who are positive or negative for human immunodeficiency virus: An epidemiologic study. Ophthalmology 1997;104:120–124.
   PubMed Web of Science ®Google Scholar
• Young TL, Robin JB, Holland GN, et al. Herpes simplex keratitis in patients with acquired immune deficiency syndrome. Ophthalmology 1989;96:1476–1479.
   PubMed Web of Science ®Google Scholar
• Kaufman HE, Azcuy AM, Varnell ED, et al. HSV-1 DNA in tears and saliva of normal adults. Invest Ophthalmol Vis Sci 2005;46:241–247.
   PubMed Web of Science ®Google Scholar
• Hill JM, Ball MJ, Neumann DM, et al. The high prevalence of herpes simplex virus type 1 DNA in human trigeminal ganglia is not a function of age or gender. J Virol 2008;82:8230–8234.
   PubMed Web of Science ®Google Scholar
• Wilhelmus KR. Epidemiology of ocular infections. In: W Tasman EA, Jaeger (Eds.). Duane’s Foundations of Clinical Ophthalmology. Philadelphia, Pennsylvania: Lippincott Williams & Wilkins, 1998; pp. 1–46.
   Google Scholar
• Perng GC, Jones C, Ciacci-Zanella J, et al. Virus-induced neuronal apoptosis blocked by the herpes simplex virus latency-associated transcript. Science 2000;287:1500–1503.
   PubMed Web of Science ®Google Scholar
• Branco FJ, Fraser NW. Herpes simplex virus type 1 latency-associated transcript expression protects trigeminal ganglion neurons from apoptosis. J Virol 2005;79:9019–9025.
   Google Scholar
• Leib DA, Coen DM, Bogard CL, et al. Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency. J Virol 1989;63:759–768.
   PubMed Web of Science ®Google Scholar
• Burton EA, Hong CS, Glorioso JC. The stable 2.0-kilobase intron of the herpes simplex virus type 1 latency-associated transcript does not function as an antisense repressor of ICP0 in nonneuronal cells. J Virol 2003;77:3516–3530.
   Google Scholar
• Remeijer L, Maertzdorf J, Doornenbal P, Verjans GM, Osterhaus AD. Herpes simplex virus 1 transmission through corneal transplantation. Lancet 2001;357:442.
   PubMed Web of Science ®Google Scholar
• Kaye S, Choudhary A. Herpes simplex keratitis. Prog Retin Eye Res 2006;25:355–380.
   PubMed Web of Science ®Google Scholar
• Remeijer L, Maertzdorf J, Buitenwerf J, Osterhaus AD, Verjans GM. Corneal herpes simplex virus type 1 superinfection in patients with recrudescent herpetic keratitis. Invest Ophthalmol Vis Sci 2002;43:358–363.
   PubMed Web of Science ®Google Scholar
• Newell CK, Martin S, Sendele D, Mercadal CM, Rouse BT. Herpes simplex virus-induced stromal keratitis: Role of T-lymphocyte subsets in immunopathology. J Virol 1989;63:769–775.
   PubMed Web of Science ®Google Scholar
• Even DL, Henley AM, Geraghty RJ. The requirements for herpes simplex virus type 1 cell-cell spread via nectin-1 parallel those for virus entry. Virus Res 2006;119:195–207.
   Google Scholar
• Spear PG. Herpes simplex virus: Receptors and ligands for cell entry. Cell Microbiol 2004;6:401–410.
   PubMed Web of Science ®Google Scholar
• Akhtar J, Shukla D. Viral entry mechanisms: Cellular and viral mediators of herpes simplex virus entry. FEBS J 2009;276:7228–7236.
   PubMed Web of Science ®Google Scholar
• Tiwari V, Oh MJ, Kovacs M, et al. Role for nectin-1 in herpes simplex virus 1 entry and spread in human retinal pigment epithelial cells. FEBS J 2008;275:5272–5285.
   Web of Science ®Google Scholar
• Oh MJ, Akhtar J, Desai P, Shukla D. A role for heparan sulfate in viral surfing. Biochem Biophys Res Commun 2010;391:176–181.
   Google Scholar
• Carfí A, Willis SH, Whitbeck JC, et al. Herpes simplex virus glycoprotein D bound to the human receptor HveA. Mol Cell 2001;8:169–179.
   PubMed Web of Science ®Google Scholar
• Takai Y, Miyoshi J, Ikeda W, Ogita H. Nectins and nectin-like molecules: Roles in contact inhibition of cell movement and proliferation. Nat Rev Mol Cell Biol 2008;9:603–615.
   PubMed Web of Science ®Google Scholar
• Stiles KM, Milne RS, Cohen GH, Eisenberg RJ, Krummenacher C. The herpes simplex virus receptor nectin-1 is down-regulated after trans-interaction with glycoprotein D. Virology 2008;373:98–111.
   Google Scholar
• Valyi-Nagy T, Sheth V, Clement C, et al. Herpes simplex virus entry receptor nectin-1 is widely expressed in the murine eye. Curr Eye Res 2004;29:303–309.
   PubMed Web of Science ®Google Scholar
• Akhtar J, Tiwari V, Oh MJ, et al. HVEM and nectin-1 are the major mediators of herpes simplex virus 1 (HSV-1) entry into human conjunctival epithelium. Invest Ophthalmol Vis Sci 2008;49:4026–4035.
   PubMed Web of Science ®Google Scholar
• Tiwari V, Clement C, Xu D, et al. Role for 3-O-sulfated heparan sulfate as the receptor for herpes simplex virus type 1 entry into primary human corneal fibroblasts. J Virol 2006;80:8970–8980.
   PubMed Web of Science ®Google Scholar
• Shukla SY, Singh YK, Shukla D. Role of nectin-1, HVEM, and PILR-alpha in HSV-2 entry into human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 2009;50:2878–2887.
   Web of Science ®Google Scholar
• Galen B, Cheshenko N, Tuyama A, Ramratnam B, Herold BC. Access to nectin favors herpes simplex virus infection at the apical surface of polarized human epithelial cells. J Virol 2006;80:12209–12218.
   PubMed Web of Science ®Google Scholar
• Kovacs SK, Tiwari V, Prandovszky E, et al. Expression of herpes virus entry mediator (HVEM) in the cornea and trigeminal ganglia of normal and HSV-1 infected mice. Curr Eye Res 2009;34:896–904.
   PubMed Web of Science ®Google Scholar
• Whitbeck JC, Peng C, Lou H, et al. Glycoprotein D of herpes simplex virus (HSV) binds directly to HVEM, a member of the tumor necrosis factor receptor superfamily and a mediator of HSV entry. J Virol 1997;71:6083–6093.
   PubMed Web of Science ®Google Scholar
• Tiwari V, Clement C, Scanlan PM, et al. A role for herpesvirus entry mediator as the receptor for herpes simplex virus 1 entry into primary human trabecular meshwork cells. J Virol 2005;79:13173–13179.
   PubMed Web of Science ®Google Scholar
• Tiwari V, Shukla SY, Yue BY, Shukla D. Herpes simplex virus type 2 entry into cultured human corneal fibroblasts is mediated by herpesvirus entry mediator. J Gen Virol 2007;88:2106–2110.
   PubMed Web of Science ®Google Scholar
• O’Donnell CD, Shukla D. A novel function of heparan sulfate in the regulation of cell-cell fusion. J Biol Chem 2009;284:29654–29665.
   Google Scholar
• Shukla D, Liu J, Blaiklock P, et al. A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry. Cell 1999;99:13–22.
   PubMed Web of Science ®Google Scholar
• Shukla D, Spear PG. Herpes viruses and heparan sulfate: An intimate relationship in aid of viral entry. J Clin Invest 2001;108:503–510.
   PubMed Web of Science ®Google Scholar
• Xia G, Chen J, Tiwari V, et al. Heparan sulfate 3-O-sulfotransferase isoform 5 generates both an antithrombin-binding site and an entry receptor for herpes simplex virus, type 1. J Biol Chem 2002;277:37912–37919.
   Google Scholar
• O’Donnell CD, Tiwari V, Oh MJ, Shukla D. A role for heparan sulfate 3-O-sulfotransferase isoform 2 in herpes simplex virus type 1 entry and spread. Virology 2006;346:452–459.
   Google Scholar
• O’Donnell CD, Kovacs M, Akhtar J, Valyi-Nagy T, Shukla D. Expanding the role of 3-O sulfated heparan sulfate in herpes simplex virus type-1 entry. Virology 2010;397:389–398.
   Google Scholar
• Satoh T, Arii J, Suenaga T, et al. PILRα is a herpes simplex virus-1 entry coreceptor that associates with glycoprotein B. Cell 2008;132:935–944.
   PubMed Web of Science ®Google Scholar
• Wang J, Fan Q, Satoh T, et al. Binding of herpes simplex virus glycoprotein B (gB) to paired immunoglobulin-like type 2 receptor alpha depends on specific sialylated O-linked glycans on gB. J Virol 2009;83:13042–13045.
   PubMed Web of Science ®Google Scholar
• Pellegrin S, Mellor H. The Rho family GTPase Rif induces filopodia through mDia2. Curr Biol 2005;15:129–133.
   PubMedGoogle Scholar
• Lehmann MJ, Sherer NM, Marks CB, Pypaert M, Mothes W. Actin- and myosin-driven movement of viruses along filopodia precedes their entry into cells. J Cell Biol 2005;170: 317–325.
   Google Scholar
• Clement C, Tiwari V, Scanlan PM, et al. A novel role for phagocytosis-like uptake in herpes simplex virus entry. J Cell Biol 2006;174:1009–1021.
   PubMed Web of Science ®Google Scholar
• Dixit R, Tiwari V, Shukla D. Herpes simplex virus type 1 induces filopodia in differentiated P19 neural cells to facilitate viral spread. Neurosci Lett 2008;440:113–118.
   Google Scholar
• Sieczkarski SB, Whittaker GR. Dissecting virus entry via endocytosis. J Gen Virol 2002;83:1535–1545.
   PubMed Web of Science ®Google Scholar