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Original Article

Platelet-Derived Growth Factor Receptor Alpha Is Associated with Oxidative Stress-Induced Retinal Cell Death

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Pages 336-340 | Received 19 Sep 2010, Accepted 16 Jan 2011, Published online: 15 Mar 2011

REFERENCES

  • Gabelt, BT, Kaufman PL. Changes in aqueous humor dynamics with age and glaucoma. Retin Eye Res. 2005;24:612–637.
  • Levin LA. Axonal loss and neuroprotection in optic neuropathies. Can J Ophthalmol. 2007;42:403–408
  • Yucel YH, Zhang Q, Weinreb RN, et al. Effects of retinal ganglion cell loss on magno-, parvo-, koniocellular pathways in the lateral geniculate nucleus and visual cortex in glaucoma. Retin Eye Res. 2003;22:465–481.
  • Weinreb RN. Glaucoma neuroprotection: What is it? Why is it needed? Can J Ophthalmol. 2007;42:396–398.
  • Tezel G. Oxidative stress in glaucomatous neurodegeneration: Mechanisms and consequences. Retin Eye Res. 2006;25:490–513.
  • Dringen R, Pfeiffer B, Hamprecht B. Synthesis of the antioxidant glutathione in neurons: Supply by astrocytes of CysGly as precursor for neuronal glutathione. J Neurosci. 1999;19:562–569.
  • Harada T, Harada C, Nakamura K, et al. The potential role of glutamate transporters in the pathogenesis of normal tension glaucoma. J Clin Invest. 2007;117:1763–1770.
  • Okumichi H, Kanamoto T, Souchelnytskyi N, et al. Proteomic analyses of retina of excitatory amino acid carrier 1 deficient mice. Proteome Sci. 2007;5:1–6.
  • Fredriksson L, Li H, Eriksson U. The PDGF family: Four gene products form five dimeric isoforms. Cytokine Growth Factor Rev. 2004;15:197–204.
  • Andrae J, Gallini R, Betsholtz C. Role of platelet-derived growth factors in physiology and medicine. Genes & Development. 2008;22:1276–1312.
  • Tallquist M, Kazlauskas A. PDGF signaling in cells and mice. Cytokine Growth Factor Rev. 2004;15:205–213.
  • Pringle NP, Mudhar HS, Collarini EJ, et al. PDGF receptors in the rat CNS: during late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage. Development. 1992;115:535–551.
  • Betsholtz C. Insight into the physiological functions of PDGF through genetic studies in mice. Cytokine Growth Factor Rev. 2004;15:215–228.
  • Fruttiger M, Calver AR, Kruger WH, et al. PDGF mediates a neuron-astrocyte interaction in the developing retina. Neuron. 1996;17:1117–1131.
  • Andrews A, Balciunaite E, Leong FL, et al. Platelet-derived growth factor plays a key role in proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci. 1999;40:2683–2689
  • Biswas SK, Zhao Y, Nagalingam A, et al. PDGF-and insulin/IGF-1-specific distinct nodes of class ІA PI3-kinase activation in normal rat retinas and RGC-5 retinal ganglion cells. Invest Ophthalmol Vis Sci. 2008;49:3687–3698.
  • Peghini P, Janzen J, Stoffel W. Glutamate transporter EAAC-1-deficient mice develope dicarboxylic aminoaciduria and behavioral abnormalities but no neurodegeneration. EMBO J. 1997;16:3822–3832.
  • Krishnamoorthy RR, Agarwal P, Prasanna G, et al. Characterization of a transformed rat retinal ganglion cell line. Mol Brain Res. 2001;86:1–12.
  • Kanamoto T, Hellman U, Heldin C-H, et al. Functional proteomics of transforming growth factor-β1-stimulated Mv1Lu epithelial cells: Rad51 as a target of TGFβ1-dependent regulation of DNA repair. EMBO J. 2002;21:1219–1230.
  • Okumichi H, Mizukami M, Kiuchi Y, et al. GABA(A) receptors are associated with retinal ganglion cell death induced by oxidative stress. Exp Eye Res. 2008;86:727–733.
  • Cox OT, Simpson DAC, Stitt AW, et al. Sources of PDGF expression in murine retina and the effect of short-term diabetes. Mol Vis. 2003;9:665–672.
  • Aoyama K, Suh SW, Hamby AM, et al. Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse. Nat Neurosci. 2006;9:119–126.
  • Fournier KM, Gonzalez MI, Robinson MB. Rapid trafficking of the neuronal glutamate transporter, EAAC1. J Biol Chem. 2004;279:34505–34513.
  • Fruttiger M, Calver AR, Richardson WD. Platelet-derived growth factor is constitutively secreted from neuronal cell bodies but not axons. Cur Biol. 2000;10:1283–1286.

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