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Current Eye Research Volume 37, 2012 - Issue 9
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Original Article

Effects of an Anti-transforming Growth Factor-β Agent (Pirfenidone) on Strabismus Surgery in Rabbits

Kyoung In JungDepartment of Ophthalmology and Visual Science, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
, MD,
Jun-Sub ChoiDepartment of Ophthalmology and Visual Science, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
, PhD,
Hyun Kyung KimDepartment of Ophthalmology and Visual Science, St. Vincent’s Hospital, The Catholic University of Korea School of Medicine, Suwon, Korea
, MD &
Sun Young ShinDepartment of Ophthalmology and Visual Science, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaCorrespondence[email protected]
, MD
Pages 770-776 | Received 01 Feb 2012, Accepted 28 Mar 2012, Published online: 06 Jun 2012

REFERENCES

  • Sondhi N, Ellis FD, Hamed LM, Helveston EM. Evaluation of an absorbable muscle sleeve to limit postoperative adhesions in strabismus surgery. Ophthalmic Surg 1987;18:441–443.
  • Cruz OA. Evaluation of mitomycin to limit postoperative adhesions in strabismus surgery. J Pediatr Ophthalmol Strabismus 1996;33:89–92.
  • Minguini N, Monteiro de Carvalho KM, Akaishi PM, De Luca IM. Histologic effect of mitomycin C on strabismus surgery in the rabbit. Invest Ophthalmol Vis Sci 2000;41:3399–3401.
  • Ozkan SB, Kir E, Culhaci N, Dayanir V. The effect of Seprafilm on adhesions in strabismus surgery-an experimental study. J AAPOS 2004;8:46–49.
  • Oku H, Shimizu T, Kawabata T et al. Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis. Eur J Pharmacol 2008;590:400–408.
  • Di Sario A, Bendia E, Macarri G et al. The anti-fibrotic effect of pirfenidone in rat liver fibrosis is mediated by downregulation of procollagen alpha1(I), TIMP-1 and MMP-2. Dig Liver Dis 2004;36:744–751.
  • Iyer SN, Gurujeyalakshmi G, Giri SN. Effects of pirfenidone on transforming growth factor-beta gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis. J Pharmacol Exp Ther 1999;291:367–373.
  • Di Sario A, Bendia E, Svegliati Baroni G et al. Effect of pirfenidone on rat hepatic stellate cell proliferation and collagen production. J Hepatol 2002;37:584–591.
  • Kim H, Choi YH, Park SJ et al. Antifibrotic effect of Pirfenidone on orbital fibroblasts of patients with thyroid-associated ophthalmopathy by decreasing TIMP-1 and collagen levels. Invest Ophthalmol Vis Sci 2010;51:3061–3066.
  • Mora JS, Sprunger DT, Helveston EM, Evan AP. Intraoperative sponge 5-fluorouracil to reduce postoperative scarring in strabismus surgery. J AAPOS 1997;1:92–97.
  • Margadant C, Sonnenberg A. Integrin-TGF-beta crosstalk in fibrosis, cancer and wound healing. EMBO Rep 2010;11:97–105.
  • Antoniu SA. Pirfenidone for the treatment of idiopathic pulmonary fibrosis. Expert Opin Investig Drugs 2006;15:823–828.
  • Lin X, Yu M, Wu K, Yuan H, Zhong H. Effects of pirfenidone on proliferation, migration, and collagen contraction of human Tenon’s fibroblasts in vitro. Invest Ophthalmol Vis Sci 2009;50:3763–3770.
  • Teller P, White TK. The physiology of wound healing: injury through maturation. Surg Clin North Am 2009;89:599–610.
  • Hewitson TD, Kelynack KJ, Tait MG et al. Pirfenidone reduces in vitro rat renal fibroblast activation and mitogenesis. J Nephrol 2001;14:453–460.
  • Zhong H, Sun G, Lin X, Wu K, Yu M. Evaluation of pirfenidone as a new postoperative antiscarring agent in experimental glaucoma surgery. Invest Ophthalmol Vis Sci 2011;52:3136–3142.
  • Mishra GP, Bagui M, Tamboli V, Mitra AK. Recent applications of liposomes in ophthalmic drug delivery. J Drug Deliv 2011;2011:863734.
  • Moon JW, Song YK, Jee JP, Kim CK, Choung HK, Hwang JM. Effect of subconjunctivally injected, liposome-bound, low-molecular-weight heparin on the absorption rate of subconjunctival hemorrhage in rabbits. Invest Ophthalmol Vis Sci 2006;47:3968–3974.
  • Baek SH, Park SJ, Jin SE, Kim JK, Kim CK, Hwang JM. Subconjunctivally injected, liposome-encapsulated streptokinase enhances the absorption rate of subconjunctival hemorrhages in rabbits. Eur J Pharm Biopharm 2009;72:546–551.
  • Cheng-Minoda K, Davidowitz J, Liebowitz A, Breinin GM. Fine structure of extraocular muscle in rabbit. J Cell Biol 1968;39:193–197.

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