Association of Tumor Necrosis Factor Alpha Promoter Polymorphism (TNF-α 238 G/A and TNF-α 308 G/A) with Diabetic Mellitus, Diabetic Retinopathy and Diabetic Nephropathy: A Meta-analysis

Refrences

• Hamaguchi K, Kimura A, Seki N, Higuchi T, Yasunaga S, Takahashi M, et al. Analysis of tumor necrosis factor-alpha promoter polymorphism in type 1 diabetes: HLA-B and -DRB1 alleles are primarily associated with the disease in Japanese. Tissue Antigens 2000;55:10–16
   PubMedGoogle Scholar
• Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993;259:87–91
   PubMed Web of Science ®Google Scholar
• Dahlen E, Dawe K, Ohlsson L, Hedlund G. Dendritic cells and macrophages are the first and major producers of TNF-alpha in pancreatic islets in the nonobese diabetic mouse. J Immunol 1998;160:3585–3593
   PubMed Web of Science ®Google Scholar
• Mauricio D, Mandrup-Poulsen T. Apoptosis and the pathogenesis of IDDM: a question of life and death. Diabetes 1998;47:1537–1543
   PubMed Web of Science ®Google Scholar
• Rabinovitch A. An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus. Diabetes Metab Rev 1998;14:129–151
   PubMed Web of Science ®Google Scholar
• Borst SE. The role of TNF-alpha in insulin resistance. Endocrine 2004;23:177–182
   PubMed Web of Science ®Google Scholar
• Moller DE. Potential role of TNF-alpha in the pathogenesis of insulin resistance and type 2 diabetes. Trends Endocrinol Metab 2000;11:212–217
   PubMed Web of Science ®Google Scholar
• Hotamisligil GS, Murray DL, Choy LN, Spiegelman BM. Tumor necrosis factor alpha inhibits signaling from the insulin receptor. Proc Natl Acad Sci USA 1994;91:4854–4858
   PubMed Web of Science ®Google Scholar
• Atkinson MA, Eisenbarth GS. Type 1 diabetes: new perspectives on disease pathogenesis and treatment. Lancet 2001;358:221–229
   PubMed Web of Science ®Google Scholar
• Tait BD, Colman PG, Morahan G, Marchinovska L, Dore E, Gellert S, et al. HLA genes associated with autoimmunity and progression to disease in type 1 diabetes. Tissue Antigens 2003;61:146–153
   PubMedGoogle Scholar
• Hussain MJ, Peakman M, Gallati H, Lo SS, Hawa M, Viberti GC, et al. Elevated serum levels of macrophage-derived cytokines precede and accompany the onset of IDDM. Diabetologia 1996;39:60–69
   PubMed Web of Science ®Google Scholar
• Bilgic S, Aktas E, Salman F, Ersahin G, Erten G, Yilmaz MT, et al. Intracytoplasmic cytokine levels and neutrophil functions in early clinical stage of type 1 diabetes. Diabetes Res Clin Pract 2008;79:31–36
   PubMedGoogle Scholar
• Christen U, Wolfe T, Mohrle U, Hughes AC, Rodrigo E, Green EA, et al. A dual role for TNF-alpha in type 1 diabetes: islet-specific expression abrogates the ongoing autoimmune process when induced late but not early during pathogenesis. J Immunol 2001;166:7023–7032
   PubMedGoogle Scholar
• Parvanova A, Iliev I, Filipponi M, Dimitrov BD, Vedovato M, Tiengo A, et al. Insulin resistance and proliferative retinopathy: a cross-sectional, case-control study in 115 patients with type 2 diabetes. J Clin Endocrinol Metab 2004;89:4371–4376
   PubMedGoogle Scholar
• Chan JC, Tomlinson B, Nicholls MG, Swaminathan R, Cheung CK, Woo J, et al. Albuminuria, insulin resistance and dyslipidaemia in Chinese patients with non-insulin-dependent diabetes (NIDDM). Diabet Med 1996;13:150–155
   PubMedGoogle Scholar
• Pociot F, Wilson AG, Nerup J, Duff GW. No independent association between a tumor necrosis factor-alpha promotor region polymorphism and insulin-dependent diabetes mellitus. Eur J Immunol 1993;23:3050–3053
   PubMed Web of Science ®Google Scholar
• Wu X, Zhang WJ, Witt CS, Abraham LJ, Christiansen FT, Dawkins RL. Haplospecific polymorphism between HLA B and tumor necrosis factor. Hum Immunol 1992;33:89–97
   PubMedGoogle Scholar
• Louis E, Franchimont D, Piron A, Gevaert Y, Schaaf-Lafontaine N, Roland S, et al. Tumour necrosis factor (TNF) gene polymorphism influences TNF-alpha production in lipopolysaccharide (LPS)-stimulated whole blood cell culture in healthy humans. Clin Exp Immunol 1998;113:401–406
   PubMed Web of Science ®Google Scholar
• Kumar N, Kaur G, Tandon N, Mehra N. Tumor necrosis factor-associated susceptibility to type 1 diabetes is caused by linkage disequilibrium with HLA-DR3 haplotypes. Hum Immunol 2012;73:566–573
   PubMedGoogle Scholar
• Javor J, Ferencik S, Bucova M, Stuchlikova M, Martinka E, Barak L, et al. Polymorphisms in the genes encoding TGF-beta1, TNF-alpha, and IL-6 show association with type 1 diabetes mellitus in the Slovak population. Arch Immunol Ther Exp (Warsz) 2010;58:385–393
   PubMed Web of Science ®Google Scholar
• Korolija M, Hadzija M, Medvidovic EP, Pavkovic P, Kapitanovic S, Renar IP, et al. Genetic evaluation of the TNF-alpha -238G>A and -308G>A promoter polymorphisms in Croatian patients with type I diabetes. Hum Immunol 2010;71:1228–1232
   PubMedGoogle Scholar
• Stayoussef M, Benmansour J, Al-Jenaidi FA, Rajab MH, Said HB, Ourtani M, et al. Identification of specific tumor necrosis factor-alpha-susceptible and -protective haplotypes associated with the risk of type 1 diabetes. Eur Cytokine Netw 2010;21:285–291
   PubMedGoogle Scholar
• Shin HD, Yang SW, Kim DH, Park Y. Independent association of tumor necrosis factor polymorphism with type 1 diabetes susceptibility. Ann N Y Acad Sci 2008;1150:76–85
   PubMed Web of Science ®Google Scholar
• Boraska V, Skrabic V, Culic VC, Becic K, Kapitanovic S, Zemunik T. Association of TNF promoter polymorphisms with type 1 diabetes in the South Croatian population. Biol Res 2008;41:157–163
   PubMedGoogle Scholar
• Paine SK, Sen A, Choudhuri S, Mondal LK, Chowdhury IH, Basu A, et al. Association of tumor necrosis factor alpha, interleukin 6, and interleukin 10 promoter polymorphism with proliferative diabetic retinopathy in type 2 diabetic subjects. Retina 2012;32:1197–1203
   PubMedGoogle Scholar
• Wang N, Huang K, Zou H, Shi Y, Zhu J, Tang W, et al. No association found between the promoter variants of TNF-alpha and diabetic retinopathy in Chinese patients with type 2 diabetes. Curr Eye Res 2008;33:377–383
   PubMed Web of Science ®Google Scholar
• Yoshioka K, Yoshida T, Takakura Y, Umekawa T, Kogure A, Toda H, et al. Relationship between polymorphisms 804C/A and 252A/G of lymphotoxin-alpha gene and -308G/A of tumor necrosis factor alpha gene and diabetic retinopathy in Japanese patients with type 2 diabetes mellitus. Metabolism. 2006;55:1406–1410
   PubMed Web of Science ®Google Scholar
• Wang Y, Ng MC, So WY, Ma R, Ko GT, Tong PC, et al. Association between tumour necrosis factor-alpha G-308A polymorphism and risk of nephropathy in obese Chinese type 2 diabetic patients. Nephrol Dial Transplant 2005;20:2733–2738
   PubMed Web of Science ®Google Scholar
• Lindholm E, Bakhtadze E, Cilio C, Agardh E, Groop L, Agardh CD. Association between LTA, TNF and AGER polymorphisms and late diabetic complications. PLoS One 2008;3:e2546
   PubMed Web of Science ®Google Scholar
• Prasad P, Tiwari AK, Kumar KM, Ammini AC, Gupta A, Gupta R, et al. Association of TGFbeta1, TNFalpha, CCR2 and CCR5 gene polymorphisms in type-2 diabetes and renal insufficiency among Asian Indians. BMC Med Genet 2007;8:20
   PubMed Web of Science ®Google Scholar
• Dotta F, Fondelli C, Di Mario U. Type 1 diabetes mellitus as a polygenic multifactorial disease: immunopathogenic mechanisms of beta-cell destruction. Acta Biomed 2005;76:14–18
   PubMedGoogle Scholar
• Mehra NK, Kumar N, Kaur G, Kanga U, Tandon N. Biomarkers of susceptibility to type 1 diabetes with special reference to the Indian population. Indian J Med Res 2007;125:321–344
   PubMedGoogle Scholar
• Kaur G, Kumar N, Szilagyi A, Blasko B, Fust G, Rajczy K, et al. Autoimmune-associated HLA-B8-DR3 haplotypes in Asian Indians are unique in C4 complement gene copy numbers and HSP-2 1267A/G. Hum Immunol 2008;69:580–587
   PubMedGoogle Scholar
• Kumar N, Kaur G, Mehra N. Genetic determinants of type 1 diabetes: immune response genes. Biomark Med 2009;3:153–173
   PubMedGoogle Scholar
• Degli-Esposti MA, Abraham LJ, McCann V, Spies T, Christiansen FT, Dawkins RL. Ancestral haplotypes reveal the role of the central MHC in the immunogenetics of IDDM. Immunogenetics 1992;36:345–356
   PubMed Web of Science ®Google Scholar
• Chan SH, Thai AC, Lin YN, Liu KF, Wee GB. Influence of gender and age at onset on the HLA associations in Chinese with insulin-dependent diabetes mellitus. Hum Immunol 1995;44:175–180
   PubMedGoogle Scholar
• Samad F, Uysal KT, Wiesbrock SM, Pandey M, Hotamisligil GS, Loskutoff DJ. Tumor necrosis factor alpha is a key component in the obesity-linked elevation of plasminogen activator inhibitor 1. Proc Natl Acad Sci USA 1999;96:6902–6907
   PubMed Web of Science ®Google Scholar
• Raptis AE, Viberti G. Pathogenesis of diabetic nephropathy. Exp Clin Endocrinol Diabetes 2001;109:S424–S437
   PubMed Web of Science ®Google Scholar
• Vinores SA, Xiao WH, Shen J, Campochiaro PA. TNF-alpha is critical for ischemia-induced leukostasis, but not retinal neovascularization nor VEGF-induced leakage. J Neuroimmunol 2007;182:73–79
   PubMed Web of Science ®Google Scholar
• Feng RN, Li Y, Sun CH. TNF 308 G/A polymorphism and type 1 diabetes: a meta-analysis. Diabetes Res Clin Pract 2009;85:e4–e7
   PubMedGoogle Scholar
• Feng RN, Zhao C, Sun CH, Li Y. Meta-analysis of TNF 308 G/A polymorphism and type 2 diabetes mellitus. PLoS One 2011;6:e18480
   PubMed Web of Science ®Google Scholar
• Feng R, Li Y, Zhao D, Wang C, Niu Y, Sun C. Lack of association between TNF 238 G/A polymorphism and type 2 diabetes: a meta-analysis. Acta Diabetol 2009;46:339–343
   PubMedGoogle Scholar