A Replication Competent HSV-1(McKrae) with a Mutation in the Amino-terminus of Glycoprotein K (gK) is Unable to Infect Mouse Trigeminal Ganglia after Cornea Infection

References

• Whitley RJ, Kimberlin DW, Roizman B. Herpes simplex viruses. Clin Infect Dis 1998;26:541–553; quiz 54–5. Epub 1998/04/03
   PubMed Web of Science ®Google Scholar
• Roizman B, Knipe DM, Whitley RJ. Herpes simplex viruses. In: Knipe DM, Howley PM, editors. Fields virology. Philadelphia, USA: Wolters Kluwer, Lippincott Williams & Wilkins; 2007. pp. 2501–2601
   Google Scholar
• Antinone SE, Smith GA. Retrograde axon transport of herpes simplex virus and pseudorabies virus: a live-cell comparative analysis. J Virol 2010;84:1504–1512. Epub 2009/11/20
   PubMed Web of Science ®Google Scholar
• Smith G. Herpesvirus transport to the nervous system and back again. Annu Rev Microbiol 2012;66:153–176. Epub 2012/06/26
   PubMed Web of Science ®Google Scholar
• Liesegang TJ, Melton LJ, 3rd Daly PJ, Ilstrup DM. Epidemiology of ocular herpes simplex. Incidence in Rochester, Minn, 1950 through 1982. Arch Ophthalmol 1989;107:1155–1159. Epub 1989/08/01
   PubMed Web of Science ®Google Scholar
• Liesegang TJ. Herpes simplex virus epidemiology and ocular importance. Cornea 2001;20:1–13
   PubMed Web of Science ®Google Scholar
• Labetoulle M, Auquier P, Conrad H, Crochard A, Daniloski M, Bouee S, et al. Incidence of herpes simplex virus keratitis in France. Ophthalmology 2005;112:888–895. Epub 2005/05/10
   PubMed Web of Science ®Google Scholar
• Cockerham G. Primary graft failure caused by herpes simplex virus type 1. Cornea 2001;20:774–775
   PubMedGoogle Scholar
• Cockerham GC, Krafft AE, McLean IW. Herpes simplex virus in primary graft failure. Arch Ophthalmol 1997;115:586–589
   PubMedGoogle Scholar
• De Kesel RJ, Koppen C, Ieven M, Zeyen T. Primary graft failure caused by herpes simplex virus type 1. Cornea 2001;20:187–190
   PubMedGoogle Scholar
• Tullo A. Pathogenesis and management of herpes simplex virus keratitis. Eye (Lond) 2003;17:919–922
   PubMed Web of Science ®Google Scholar
• Nicola AV, Hou J, Major EO, Straus SE. Herpes simplex virus type 1 enters human epidermal keratinocytes, but not neurons, via a pH-dependent endocytic pathway. J Virol 2005;79:7609–7616
   PubMed Web of Science ®Google Scholar
• Qie L, Marcellino D, Herold BC. Herpes simplex virus entry is associated with tyrosine phosphorylation of cellular proteins. Virology. 1999;256:220–227
   PubMed Web of Science ®Google Scholar
• Milne RS, Nicola AV, Whitbeck JC, Eisenberg RJ, Cohen GH. Glycoprotein D receptor-dependent, low-pH-independent endocytic entry of herpes simplex virus type 1. J Virol 2005;79:6655–6663
   PubMed Web of Science ®Google Scholar
• Connolly SA, Jackson JO, Jardetzky TS, Longnecker R. Fusing structure and function: a structural view of the herpesvirus entry machinery. Nat Rev Microbiol 2011;9:369–381
   PubMed Web of Science ®Google Scholar
• Mettenleiter TC, Klupp BG, Granzow H. Herpesvirus assembly: an update. Virus Res 2009;143:222–234
   PubMed Web of Science ®Google Scholar
• Johnson DC, Baines JD. Herpesviruses remodel host membranes for virus egress. Nat Rev Microbiol 2011;9:382–394
   PubMed Web of Science ®Google Scholar
• Diefenbach RJ, Miranda-Saksena M, Douglas MW, Cunningham AL. Transport and egress of herpes simplex virus in neurons. Rev Med Virol 2008;18:35–51
   PubMed Web of Science ®Google Scholar
• Debroy C, Pederson N, Person S. Nucleotide sequence of a herpes simplex virus type 1 gene that causes cell fusion. Virology 1985;145:36–48
   PubMed Web of Science ®Google Scholar
• MacLean CA, Efstathiou S, Elliott ML, Jamieson FE, McGeoch DJ. Investigation of herpes simplex virus type 1 genes encoding multiply inserted membrane proteins. J Gen Virol 1991;72(Pt 4):897–906
   PubMedGoogle Scholar
• Ramaswamy R, Holland TC. In vitro characterization of the HSV-1 UL53 gene product. Virology 1992;186:579–587
   PubMed Web of Science ®Google Scholar
• Foster TP, Alvarez X, Kousoulas KG. Plasma membrane topology of syncytial domains of herpes simplex virus type 1 glycoprotein K (gK): the UL20 protein enables cell surface localization of gK but not gK-mediated cell-to-cell fusion. J Virol 2003;77:499–510
   PubMed Web of Science ®Google Scholar
• Melancon JM, Foster TP, Kousoulas KG. Genetic analysis of the herpes simplex virus type 1 (HSV-1) UL20 protein domains involved in cytoplasmic virion envelopment and virus-induced cell fusion. J Virol 2004;78:7329–7343
   PubMed Web of Science ®Google Scholar
• Hutchinson L, Goldsmith K, Snoddy D, Ghosh H, Graham FL, Johnson DC. Identification and characterization of a novel herpes simplex virus glycoprotein, gK, involved in cell fusion. J Virol 1992;66:5603–5609
   PubMed Web of Science ®Google Scholar
• Foster TP, Chouljenko VN, Kousoulas KG. Functional and physical interactions of the herpes simplex virus type 1 UL20 membrane protein with glycoprotein K. J Virol 2008;82:6310–6323
   PubMed Web of Science ®Google Scholar
• Foster TP, Melancon JM, Baines JD, Kousoulas KG. The Herpes Simplex Virus Type 1 UL20 Protein Modulates Membrane Fusion Events during Cytoplasmic Virion Morphogenesis and Virus-Induced Cell Fusion. J Virol 2004;78:5347–5357
   PubMed Web of Science ®Google Scholar
• Foster TP, Melancon JM, Kousoulas KG. An alpha-helical domain within the carboxyl terminus of herpes simplex virus type 1 (HSV-1) glycoprotein B (gB) is associated with cell fusion and resistance to heparin inhibition of cell fusion. Virology 2001;287:18–29
   PubMed Web of Science ®Google Scholar
• Melancon JM, Foster TP, Kousoulas KG. Genetic analysis of the herpes simplex virus type 1 (HSV-1) UL20 protein domains involved in cytoplasmic virion envelopment and virus-induced cell fusion. J Virol 2004;78:7329--7343
   Google Scholar
• Jambunathan N, Chowdhury S, Subramanian R, Chouljenko VN, Walker JD, Kousoulas KG. Site-specific proteolytic cleavage of the amino terminus of herpes simplex virus glycoprotein K on virion particles inhibits virus entry. J Virol 2011;85:12910–12918
   PubMed Web of Science ®Google Scholar
• Foster TP, Kousoulas KG. Genetic analysis of the role of herpes simplex virus type 1 glycoprotein K in infectious virus production and egress. J Virol 1999;73:8457–8468
   PubMed Web of Science ®Google Scholar
• Hutchinson L, Roop-Beauchamp C, Johnson DC. Herpes simplex virus glycoprotein K is known to influence fusion of infected cells, yet is not on the cell surface. J Virol 1995;69:4556–6453
   PubMed Web of Science ®Google Scholar
• Jayachandra S, Baghian A, Kousoulas KG. Herpes simplex virus type 1 glycoprotein K is not essential for infectious virus production in actively replicating cells but is required for efficient envelopment and translocation of infectious virions from the cytoplasm to the extracellular space. J Virol 1997;71:5012–5024
   PubMed Web of Science ®Google Scholar
• Chouljenko VN, Iyer AV, Chowdhury S, Chouljenko DV, Kousoulas KG. The amino terminus of herpes simplex virus type 1 glycoprotein K (gK) modulates gB-mediated virus-induced cell fusion and virion egress. J Virol 2009;83:12301–12313
   PubMed Web of Science ®Google Scholar
• Chouljenko VN, Iyer AV, Chowdhury S, Kim J, Kousoulas KG. The herpes simplex virus type 1 UL20 protein and the amino terminus of glycoprotein K (gK) physically interact with gB. J Virol 2010;84:8596–8606
   PubMed Web of Science ®Google Scholar
• Foster TP, Rybachuk GV, Kousoulas KG. Glycoprotein K specified by herpes simplex virus type 1 is expressed on virions as a Golgi complex-dependent glycosylated species and functions in virion entry. J Virol 2001;75:12431–12438
   PubMed Web of Science ®Google Scholar
• Chowdhury S, Chouljenko VN, Naderi M, Kousoulas KG. The amino terminus of herpes simplex virus 1 glycoprotein K is required for virion entry via the paired immunoglobulin-like type-2 receptor alpha. J Virol 2013;87:3305–3313
   PubMed Web of Science ®Google Scholar
• David AT, Baghian A, Foster TP, Chouljenko VN, Kousoulas KG. The herpes simplex virus type 1 (HSV-1) glycoprotein K(gK) is essential for viral corneal spread and neuroinvasiveness. Curr Eye Res 2008;33:455–467
   PubMed Web of Science ®Google Scholar
• David AT, Saied A, Charles A, Subramanian R, Chouljenko VN, Kousoulas KG. A herpes simplex virus 1 (McKrae) mutant lacking the glycoprotein K gene is unable to infect via neuronal axons and egress from neuronal cell bodies. MBio 2012;3:e00144–12
   Web of Science ®Google Scholar
• Tanaka M, Kagawa H, Yamanashi Y, Sata T, Kawaguchi Y. Construction of an excisable bacterial artificial chromosome containing a full-length infectious clone of herpes simplex virus type 1: viruses reconstituted from the clone exhibit wild-type properties in vitro and in vivo. J Virol 2003;77:1382–1391
   PubMed Web of Science ®Google Scholar
• Tischer BK, von Einem J, Kaufer B, Osterrieder N. Two-step red-mediated recombination for versatile high-efficiency markerless DNA manipulation in Escherichia coli. Biotechniques 2006;40:191–197
   PubMed Web of Science ®Google Scholar
• Subramanian R, D'Auvergne O, Kong H, Kousoulas KG. The cytoplasmic terminus of Kaposi's sarcoma-associated herpesvirus glycoprotein B is not essential for virion egress and infectivity. J Virol 2008;82:7144–7154
   PubMed Web of Science ®Google Scholar
• Subramanian R, Sehgal I, D'Auvergne O, Kousoulas KG. Kaposi's sarcoma-associated herpesvirus glycoproteins B and K8.1 regulate virion egress and synthesis of vascular endothelial growth factor and viral interleukin-6 in BCBL-1 cells. J Virol 2010;84:1704–1714
   PubMed Web of Science ®Google Scholar
• Wang C, Fu T, Xia C, Li Z. Changes in mouse corneal epithelial innervation with age. Invest Ophthalmol Visual Sci 2012;53:5077–5084
   PubMed Web of Science ®Google Scholar
• Belmonte C, Gallar J. Corneal nociceptors. In: Belmonte C. CFe, editor. Neurobiology of nociceptors. Oxford: Oxford University Press; 1996. pp. 146–183
   Google Scholar
• Ghiasi H, Bahri S, Nesburn AB, Wechsler SL. Protection against herpes simplex virus-induced eye disease after vaccination with seven individually expressed herpes simplex virus 1 glycoproteins. Invest Ophthalmol Vis Sci 1995;36:1352–1360
   PubMed Web of Science ®Google Scholar
• Ghiasi H, Kaiwar R, Nesburn AB, Slanina S, Wechsler SL. Expression of seven herpes simplex virus type 1 glycoproteins (gB, gC, gD, gE, gG, gH, and gI): comparative protection against lethal challenge in mice. J Virol 1994;68:2118–2126
   PubMed Web of Science ®Google Scholar
• Ghiasi H, Cai S, Slanina S, Nesburn AB, Wechsler SL. Nonneutralizing antibody against the glycoprotein K of herpes simplex virus type-1 exacerbates herpes simplex virus type-1-induced corneal scarring in various virus-mouse strain combinations. Invest Ophthalmol Vis Sci 1997;38:1213–1221
   PubMed Web of Science ®Google Scholar
• Ghiasi H, Slanina S, Nesburn AB, Wechsler SL. Characterization of baculovirus-expressed herpes simplex virus type 1 glycoprotein K. J Virol 1994;68:2347–2354
   PubMed Web of Science ®Google Scholar
• Mott KR, Perng GC, Osorio Y, Kousoulas KG, Ghiasi H. A Recombinant Herpes Simplex Virus Type 1 Expressing Two Additional Copies of gK Is More Pathogenic than Wild-Type Virus in Two Different Strains of Mice. J Virol 2007;81:12962–12972
   PubMed Web of Science ®Google Scholar
• Mott KR, Osorio Y, Maguen E, Nesburn AB, Wittek AE, Cai S, et al. Role of anti-glycoproteins D (anti-gD) and K (anti-gK) IgGs in pathology of herpes stromal keratitis in humans. Invest Ophthalmol Visual Sci 2007;48:2185–2193
   PubMed Web of Science ®Google Scholar