932
Views
30
CrossRef citations to date
0
Altmetric
Mini-Review

The Pathogenesis of Raised Intraocular Pressure in Uveitis

, &
Pages 137-149 | Received 08 May 2014, Accepted 04 Feb 2015, Published online: 14 May 2015

References

  • Siddique SS, Suelves AM, Baheti U, Foster CS. Glaucoma and uveitis. Surv Ophthalmol 2013;58:1–10
  • Neri P, Azuara-Blanco A, Forrester JV. Incidence of glaucoma in patients with uveitis. J Glaucoma 2004;13:461–465
  • Moorthy R, Mermoud A, Baerveldt G, Minckler D, Lee P, Rao N. Glaucoma associated with uveitis. Surv Ophthalmol 1997;41:361–394
  • Beer J, Die Lehre v. d. Augenkrankheiten. Vienna 1813;1:633
  • Merayo-Lloves J, Power WJ, Rodriguez A, Pedroza-Seres M, Foster CS. Secondary glaucoma in patients with uveitis. Ophthalmologica 1999;213:300–304
  • Takahashi T, Ohtani S, Miyata K, Miyata N, Shirato S, Mochizuki M. A clinical evaluation of uveitis-associated secondary glaucoma. Jpn J Ophthalmol 2002;46:556–562
  • Elliot R. A treatise on glaucoma. London: Oxford Med Publ; 1918
  • Jones III RD. Corticosteroid-induced ocular hypertension and glaucoma: a brief review and update of the literature. Curr Opin Ophthalmol 2006;17:163–167
  • Toris CB, Pederson JE. Aqueous humor dynamics in experimental iridocyclitis. Invest Ophthalmol Vis Sci 1987;28:477–481
  • Bill A, Phillips CI. Uveoscleral drainage of aqueous humour in human eyes. Exp Eye Res 1971;12:275–281
  • Bill A. Aqueous humor dynamics in monkeys (Macaca irus and Cercopithecus ethiops). Exp Eye Res 1971;11:195–206
  • Toris C, Camras C, Yablonski M. Effects of PhXA41, a new prostaglandin F2a analogue, on aqueous humor dynamics in human eyes. Ophthalmology 1993;100:1297–1304
  • Toris CB, Yablonski ME, Wang Y-L, Camras CB. Aqueous humor dynamics in the aging human eye. Am J Ophthalmol 1999;127:407–412
  • Toris CB, Koepsell SA, Yablonski ME, Camras CB. Aqueous humor dynamics in ocular hypertensive patients. J Glaucoma 2002;11:253–258
  • Mermoud A, Baerveldt G, Mickler DS, Wu GS, Rao NA. Animal model for uveitic glaucoma. Graefes Arch Clin Exp Ophthalmol 1994;232:553–560
  • Howes EJ, Cruse VK. The structural basis of altered vascular permeability following introcular inflammation. Arch Ophthalmol 1978;96:1668–1676
  • Johnson D, Liesegang TJ, Brubaker RF. Aqueous humor dynamics in Fuchs’ uveitis syndrome. Am J Ophthalmol 1983;95:783–787
  • Eakins K. Prostaglandin and non-prostaglandin mediated breakdown of the blood-aqueous barrier. Exp Eye Res 1977;25:483
  • Horsley M, Chen T. The use of prostaglandin analogs in the uveitic patient. Semin Ophthalmol 2011;26:285–289
  • Eakins K, Whitelocke R, Bennett A, Martenet A. Prostaglandin-like activity in ocular inflammation. Br J Med 1972;3:452–453
  • Herbort C, Mermoud A, Schnyder C, Pittet N. Anti-inflammatory effect of diclofenac drops after argon laser trabeculoplasty. Arch Ophthalmol 1993;111:481–483
  • Hayashi M, Yablonski ME, Bito LZ. Eicosanoids as a new class of ocular hypotensive agents. 2. Comparison of the apparent mechanism of the ocular hypotensive effects of A and F type prostaglandins. Invest Ophthalmol Vis Sci 1987;28:1639–1643
  • Toris CB, Gabelt BT, Kaufman PL. Update on the mechanism of action of topical prostaglandins for intraocular pressure reduction. Surv Ophthalmol 2008;53:S107–S120
  • Lim KS, Nau CB, O’Byrne MM, Hodge DO, Toris CB, McLaren JW, et al. Mechanism of action of bimatoprost, latanoprost, and travoprost in healthy subjects. A crossover study. Ophthalmology 2008;115:790.e4–795.e4
  • Christiansen GA, Nau CB, McLaren JW, Johnson DH. Mechanism of ocular hypotensive action of bimatoprost (Lumigan) in patients with ocular hypertension or glaucoma. Ophthalmology 2004;111:1658–1662
  • Ladas JG, Yu F, Loo R, Davis JL, Coleman AL, Levinson RD, et al. Relationship between aqueous humor protein level and outflow facility in patients with uveitis. Invest Ophthalmol Vis Sci 2001;42:2584–2588
  • Epstein DL, Hashimoto JM, Grant WM. Serum obstruction of aqueous outflow in enucleated eyes. Am J Ophthalmol 1978;86:101–105
  • Peretz WL, Tomasi T. Aqueous humor proteins in uveitis. Immunoelectrophoretic and gel diffusion studies on normal and pathological human aqueous humor. Arch Ophthalmol 1961;65:20–23
  • Epstein DL, Jedziniak JA, Grant WM. Obstruction of aqueous outflow by lens particles and by heavy-molecular-weight soluble lens proteins. Invest Ophthalmol Vis Sci 1978;17:272–277
  • Altamirano D, Mermoud A, Pittet N, van Melle G, Herbort CP. Aqueous humor analysis after Nd:YAG laser capsulotomy with the laser flare-cell meter. J Cataract Refract Surg 1992;18:554–558
  • Ge J, Wand M, Chiang R, Paranhos A, Shields MB. Long-term effect of Nd:YAG laser posterior capsulotomy on intraocular pressure. Arch Ophthalmol 2000;118:1334–1337
  • Lambrou FH, Vela MA, Woods W. Obstruction of the trabecular meshwork by retinal rod outer segments. Arch Ophthalmol 1989;107:742–745
  • Fiore PM, Melamed S, Epstein DL. Trabecular precipitates and elevated intraocular pressure following argon laser trabeculoplasty. Ophthalmic Surg 1989;20:697–701
  • Cohen RG, Wu HK, Schuman JS. Glaucoma with inflammatory precipitates on the trabecular meshwork: a report of Grant’s syndrome with ultrasound biomicroscopy of precipitates. J Glaucoma 1996;5:266–270
  • Richardson TM, Hutchinson BT, Grant WM. The outflow tract in pigmentary glaucoma: a light and electron microscopic study. Arch Ophthalmol 1977;95:1015–1025
  • Hogan MJ, Kimura SJ, Thygeson P. Pathology of herpes simplex kerato-iritis. Trans Am Ophthalmol Soc 1963;61:75–99
  • Townsend WM, Kaufman HE. Pathogenesis of glaucoma and endothelial changes in herpetic kerato-uveitis in rabbits. Am J Ophthalmol 1971;71:904–910
  • Falcon MG, Williams HP. Herpes simplex kerato-uveitis and glaucoma. Trans Ophthalmol Soc UK 1978;98:101–104
  • Horai R, Caspi RR. Cytokines in autoimmune uveitis. J Interferon Cytokine Res 2011;31:733–744
  • Deschenes J, Char D, Kaleta S. Activated T lymphocytes in uveitis. Br J Ophthalmol 1988;72:83–87
  • Murray P, Clay C, Mappin C, Salmon M. Molecular analysis of resolving immune responses in uveitis. Clin Exp Immunol 1999;117:455–461
  • Murphy CC, Duncan L, Forrester J V, Dick AD. Systemic CD4(+) T cell phenotype and activation status in intermediate uveitis. Br J Ophthalmol 2004;88:412–416
  • Rao NA, Wu GS. Free radical mediated photoreceptor damage in uveitis. Prog Retin Eye Res 2000;19:41–68
  • Sorkhabi R, Ghorbanihaghjo A, Javadzadeh A, Rashtchizadeh N, Moharrery M. Oxidative DNA damage and total antioxidant status in glaucoma patients. Mol Vis 2011;17:41–46
  • Oshida E, Matsumoto Y, Arai K. Free radicals in the aqueous humor of patients with glaucoma. Clin Ophthalmol 2010;4:653–660
  • Rao PV, Deng PF, Kumar J, Epstein DL. Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632. Invest Ophthalmol Vis Sci 2001;42:1029–1037
  • Rao PV, Deng P, Maddala R, Epstein DL, Li C-Y, Shimokawa H. Expression of dominant negative Rho-binding domain of Rho-kinase in organ cultured human eye anterior segments increases aqueous humor outflow. Mol Vis 2005;11:288–297
  • Oguz E, Alasehirli B, Pehlivan Y, Onat AM, Oztuzcu S, Ozkara E, et al. Association between Rho-kinase (ROCK2) gene polymorphisms and Behçet’s disease. Transl Res 2012;160:428–434
  • Weinreb RN, Sandman R, Ryder MI, Friberg TR. Angiotensin-converting enzyme activity in human aqueous humor. Arch Ophthalmol 1985;103:34–36
  • Shah GB, Sharma S, Mehta AA, Goyal RK. Oculohypotensive effect of angiotensin-converting enzyme inhibitors in acute and chronic models of glaucoma. J Cardiovasc Pharmacol 2000;36:169–175
  • Mehta A, Iyer L, Parmar S, Shah G, Goyal R. Oculohypotensive effect of perindopril in acute and chronic models of glaucoma in rabbits. Can J Physiol Pharmacol 2010;88:595–600
  • Hirooka K, Shiraga F. Potential role for angiotensin-converting enzyme inhibitors in the treatment of glaucoma. Clin Ophthalmol 2007;1:217–223
  • Armaly MF, Becker B. Intraocular pressure response to topical corticosteroids. Fed Proc 1965;24:1274–1278
  • Becker B. Intraocular pressure response to topical corticosteroids. Invest Ophthalmol 1965;4:198–205
  • Tripathi RC, Parapuram SK, Tripathi BJ, Zhong Y, Chalam KV. Corticosteroids and glaucoma risk. Drugs Aging 1999;15:439–450
  • Kersey JP, Broadway DC. Corticosteroid-induced glaucoma: a review of the literature. Eye (Lond) 2006;20:407–416
  • Razeghinejad MR, Katz LJ. Steroid-induced iatrogenic glaucoma. Ophthalmic Res 2012;47:66–80
  • Renfro L, Snow JS. Ocular effects of topical and systemic steroids. Dermatol Clin 1992;10:505–512
  • Yue BY. The extracellular matrix and its modulation in the trabecular meshwork. Surv Ophthalmol 1996;40:379–390
  • Armaly MF. Effect of corticosteroids on intraocular pressure and fluid dynamics. I. The effect of dexamethasone in the normal eye. Arch Ophthalmol 1963;70:482–491
  • François J. Corticosteroid glaucoma. Ann Ophthalmol 1977;9:1075–1080
  • François J. Corticosteroid glaucoma. Ophthalmologica 1984;188:76–81
  • Knepper PA, Collins JA, Frederick R. Effects of dexamethasone, progesterone, and testosterone on IOP and GAGs in the rabbit eye. Invest Ophthalmol Vis Sci 1985;26:1093–1100
  • Johnson DH, Knepper PA. Microscale analysis of the glycosaminoglycans of human trabecular meshwork: a study in perfusion cultured eyes. J Glaucoma 1994;3:58–69
  • Stone EM. Identification of a gene that causes primary open angle glaucoma. Science 1997;275:668–670
  • Fautsch MP, Bahler CK, Jewison DJ, Johnson DH. Recombinant TIGR/MYOC increases outflow resistance in the human anterior segment. Invest Ophthalmol Vis Sci 2000;41:4163–4168
  • Fingert JH, Clark AF, Craig JE, Alward WL, Snibson GR, McLaughlin M, et al. Evaluation of the myocilin (MYOC) glaucoma gene in monkey and human steroid-induced ocular hypertension. Invest Ophthalmol Vis Sci 2001;42:145–152
  • Lo WR. Tissue differential microarray analysis of dexamethasone induction reveals potential mechanisms of steroid glaucoma. Invest Ophthalmol Vis Sci 2003;44:473–485
  • Friedman DS, Holbrook JT, Ansari H, Alexander J, Burke A, Reed SB, et al. Risk of elevated intraocular pressure and glaucoma in patients with uveitis: results of the multicenter uveitis steroid treatment trial. Ophthalmology 2013;120:1571–1579
  • Yamamoto S, Pavan-Langston D, Tada R, Yamamoto R, Kinoshita S, Nishida K, et al. Possible role of herpes simplex virus in the origin of Posner-Schlossman syndrome. Am J Ophthalmol 1995;119:796–798
  • Hedayatfar A, Chee S-P. Posner-Schlossman syndrome associated with cytomegalovirus infection: a case series from a non-endemic area. Int Ophthalmol 2014;34:1123–1129
  • Rodier-Bonifas C, Cornut P-L, Billaud G, Lina B, Burillon C, Denis P. [Cytomegalovirus research using polymerase chain reaction in Posner-Schlossman syndrome]. J Fr Ophtalmol 2011;34:24–29
  • Smith SL, Pruitt CA, Sine CS, Hudgins AC, Stewart WC. Latanoprost 0.005% and anterior segment uveitis. Acta Ophthalmol Scand 1999;77:668–672
  • Warwar RE, Bullock JD, Ballal D. Cystoid macular edema and anterior uveitis associated with latanoprost use. Experience and incidence in a retrospective review of 94 patients. Ophthalmology 1998;105:263–268
  • Fechtner RD, Khouri AS, Zimmerman TJ, Bullock J, Feldman R, Kulkarni P, et al. Anterior uveitis associated with latanoprost. Am J Ophthalmol 1998;126:37–41
  • Packer M, Fine IH, Hoffman RS. Bilateral nongranulomatous anterior uveitis associated with bimatoprost. J Cataract Refract Surg 2003;29:2242–2243
  • Kumarasamy M, Desai SP. Anterior uveitis is associated with travoprost. BMJ 2004;329:205
  • Aydin S, Ozcura F. Corneal oedema and acute anterior uveitis after two doses of travoprost. Acta Ophthalmol Scand 2007;85:693–694
  • Kessler C, Christ T. Incidence of uveitis in glaucoma patients using metipranolol. J Glaucoma 1993;2:166–170
  • Chang JH, McCluskey P, Missotten T, Ferrante P, Jalaludin B, Lightman S. Use of ocular hypotensive prostaglandin analogues in patients with uveitis: does their use increase anterior uveitis and cystoid macular oedema?. Br J Ophthalmol 2008;92:916–921
  • Markomichelakis NN, Kostakou A, Halkiadakis I, Chalkidou S, Papakonstantinou D, Georgopoulos G. Efficacy and safety of latanoprost in eyes with uveitic glaucoma. Graefes Arch Clin Exp Ophthalmol 2009;247:775–780
  • Sung VCT, Barton K. Management of inflammatory glaucomas. Curr Opin Ophthalmol 2004;15:136–140
  • Stavrou P, Murray PI. Long-term follow-up of trabeculectomy without antimetabolites in patients with uveitis. Am J Ophthalmol 1999;128:434–439
  • Towler HM, Bates AK, Broadway DC, Lightman S. Primary trabeculectomy with 5-fluorouracil for glaucoma secondary to uveitis. Ocul Immunol Inflamm 1995;3:163–170
  • Towler HM, McCluskey P, Shaer B, Lightman S. Long-term follow-up of trabeculectomy with intraoperative 5-fluorouracil for uveitis-related glaucoma. Ophthalmology 2000;107:1822–1828
  • Jampel HD, Jabs DA, Quigley HA. Trabeculectomy with 5-fluorouracil for adult inflammatory glaucoma. Am J Ophthalmol 1990;109:168–173
  • Novak-Laus K, Mandić Z, Iveković R, Korsić J, Tedeschi-Reiner E, Masnec-Paskvalin S, et al. Trabeculectomy with mitomycin C in glaucoma associated with uveitis. Coll Antropol 2005;29:17–20
  • Yalvac IS, Sungur G, Turhan E, Eksioglu U, Duman S. Trabeculectomy with mitomycin-C in uveitic glaucoma associated with Behçet disease. J Glaucoma 2004;13:450–453
  • Auer C, Mermoud A, Herbort CP. Deep sclerectomy for the management of uncontrolled uveitic glaucoma: preliminary data. Klin Monbl Augenheilkd 2004;221:339–342
  • Anand N. Deep sclerectomy with mitomycin C for glaucoma secondary to uveitis. Eur J Ophthalmol 2011;21:708–714
  • Souissi K, El Afrit MA, Trojet S, Kraiem A. [Deep sclerectomy for the management of uveitic glaucoma]. J Fr Ophtalmol 2006;29:265–268
  • Ang GS, Varga Z, Shaarawy T. Postoperative infection in penetrating versus non-penetrating glaucoma surgery. Br J Ophthalmol 2010;94:1571–1576
  • Da Mata A, Burk SE, Netland PA, Baltatzis S, Christen W, Foster CS. Management of uveitic glaucoma with Ahmed glaucoma valve implantation. Ophthalmology 1999;106:2168–2172
  • Gil-Carrasco F, Salinas-VanOrman E, Recillas-Gispert C, Paczka JA, Gilbert ME, Arellanes-García L. Ahmed valve implant for uncontrolled uveitic glaucoma. Ocul Immunol Inflamm 1998;6:27–37
  • Papadaki TG, Zacharopoulos IP, Pasquale LR, Christen WB, Netland PA, Foster CS. Long-term results of Ahmed glaucoma valve implantation for uveitic glaucoma. Am J Ophthalmol 2007;144:62–69
  • Bettis DI, Morshedi RG, Chaya C, Goldsmith J, Crandall A, Zabriskie N. Trabeculectomy with mitomycin C or Ahmed valve implantation in eyes with uveitic glaucoma. J Glaucoma 2014. [Epub ahead of print]. doi:10.1097/IJG.0000000000000195
  • Murphy CC, Burnett CAM, Spry PGD, Broadway DC, Diamond JP. A two centre study of the dose-response relation for transscleral diode laser cyclophotocoagulation in refractory glaucoma. Br J Ophthalmol 2003;87:1252–1257
  • Toris CB, Yablonski ME, Wang YL, Hayashi M. Prostaglandin A2 increases uveoscleral outflow and trabecular outflow facility in the cat. Exp Eye Res 1995;61:649–657
  • Fortuna E, Cervantes-Castañeda RA, Castañeda-Cervantes RA, Bhat P, Doctor P, Foster CS. Flare-up rates with bimatoprost therapy in uveitic glaucoma. Am J Ophthalmol 2008;146:876–882

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.