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Biomarkers

Association of Exhaled Nitric Oxide to Asthma Burden in Asthmatics on Inhaled Corticosteroids

, M.D., Ph.D., , M.D., M.S., , M.S., , M.D., , M.D., , M.D. & , M.S. show all
Pages 8-17 | Published online: 15 Dec 2010

Rererences

  • Nordvall SL, Janson C, Kalm-Stephens P, Foucard T, Toren K, Alving K. Exhaled nitric oxide in a population-based study of asthma and allergy in schoolchildren. Allergy 2005; 60(4):469–475.
  • Zietkowski Z, Bodzenta-Lukaszyk A, Tomasiak MM, Skiepko R, Szmitkowski M. Comparison of exhaled nitric oxide measurement with conventional tests in steroid-naive asthma patients. J Investig Allergol Clin Immunol 2006; 16(4):239–246.
  • Taylor DR, Pijnenburg MW, Smith AD, de Jongste JC. Exhaled nitric oxide measurements: clinical application and interpretation. Thorax 2006; 61(9):817–827.
  • Pedrosa M, Cancelliere N, Barranco P, Lopez-Carrasco V, Quirce S. Usefulness of exhaled nitric oxide for diagnosing asthma. J Asthma 2010; 47(7):817–821.
  • Pijnenburg MW, Hofhuis W, Hop WC, de Jongste JC. Exhaled nitric oxide predicts asthma relapse in children with clinical asthma remission. Thorax 2005; 60(3):215–218.
  • Harkins MS, Fiato KL, Iwamoto GK. Exhaled nitric oxide predicts asthma exacerbation. J Asthma 2004; 41(4):471–476.
  • Sorkness CA, Lemanske RF, Jr., Mauger DT, Boehmer SJ, Chinchilli VM, Martinez FD, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, Bloomberg GR, Covar RA, Guilbert TW, Heldt G, Larsen G, Mellon MH, Morgan WJ, Moss MH, Spahn JC, Taussig LM. Long-term comparison of 3 controller regimens for mild-moderate persistent childhood asthma: the Pediatric Asthma Controller Trial. J Allergy Clin Immunol 2007; 119(1):64–72.
  • Montuschi P, Mondino C, Koch P, Barnes PJ, Ciabattoni G. Effects of a leukotriene receptor antagonist on exhaled leukotriene E4 and prostanoids in children with asthma. J Allergy Clin Immunol 2006; 118(2):347–353.
  • Wilson AM, Duong M, Pratt B, Dolovich M, O'Byrne PM. Anti-inflammatory effects of once daily low dose inhaled ciclesonide in mild to moderate asthmatic patients. Allergy 2006; 61(5):537–542.
  • Silkoff PE, McClean PA, Slutsky AS, Caramori M, Chapman KR, Gutierrez C, Zamel N. Exhaled nitric oxide and bronchial reactivity during and after inhaled beclomethasone in mild asthma. J Asthma 1998; 35(6):473–479.
  • Syk J, Unden AL, Alving K. Relationship between exhaled nitric oxide and IgE sensitisation in patients with asthma: influence of steroid treatment. Clin Respir J 2009; 3(3):143–151.
  • Expert Panel 3 Report for the National Asthma Education Prevention Program. Available at: http://wwwnhlbinihgov/guidelines/asthma/epr3/index htm 2007.
  • The Global Initiative for Asthma. NIH Publication No. 02-3659. 2006. U.S. Department of Health and Human Services Public Health Service, NIH, NHLBI.
  • Nathan RA, Sorkness CA, Kosinski M, Schatz M, Li JT, Marcus P, Murray JJ, Pendergraft TB. Development of the asthma control test: a survey for assessing asthma control. J Allergy Clin Immunol 2004; 113(1):59–65.
  • Schatz M, Sorkness CA, Li JT, Marcus P, Murray JJ, Nathan RA, Kosinki M, Pendergraft TB, Jhingran P. Asthma Control Test: reliability, validity, and responsiveness in patients not previously followed by asthma specialists. J Allergy Clin Immunol 2006; 117(3):549–556.
  • Zeiger RS, Schatz M, Li Q, Zhang F, Purdum A, Chen W. Step-up Care Improves Impairment In Uncontrolled Asthma: Administrative Data Study. Am J Manag Care, (in Press). 2010.
  • Silkoff PE, Wakita S, Chatkin J, Ansarin K, Gutierrez C, Caramori M, McClean P, Slutsky AS, Zamel N, Chapman KR. Exhaled nitric oxide after beta2-agonist inhalation and spirometry in asthma. Am J Respir Crit Care Med 1999; 159(3):940–944.
  • ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005. Am J Respir Crit Care Med 2005; 171(8):912–930.
  • Gill M, Graff GR, Adler AJ, Dweik RA. Validation study of fractional exhaled nitric oxide measurements using a handheld monitoring device. J Asthma 2006; 43(10):731–734.
  • Standardization of Spirometry, 1994 Update. American Thoracic Society. Am J Respir Crit Care Med 1995; 152(3):1107–1136.
  • Crapo RO. Spirometry: quality control and reproducibility criteria. Am Rev Respir Dis 1991; 143(6):1212–1213.
  • Schatz M, Zeiger RS, Vollmer WM, Mosen D, Apter AJ, Stibolt TB, Leong A, Johnson MS, Mendoza G, Cook EF. Validation of a beta-agonist long-term asthma control scale derived from computerized pharmacy data. J Allergy Clin Immunol 2006; 117(5):995–1000.
  • Schatz M, Zeiger RS, Vollmer WM, Mosen D, Mendoza G, Apter AJ, Stibolt TB, Leong A, Johnson MS, Cook EF. The controller-to-total asthma medication ratio is associated with patient-centered as well as utilization outcomes. Chest 2006; 130(1):43–50.
  • Schatz M, Nakahiro R, Crawford W, Mendoza G, Mosen D, Stibolt TB. Asthma quality-of-care markers using administrative data. Chest 2005; 128(4):1968–1973.
  • Zou G. A modified poisson regression approach to prospective studies with binary data. Am J Epidemiol 2004; 159(7):702–706.
  • Barros AJ, Hirakata VN. Alternatives for logistic regression in cross-sectional studies: an empirical comparison of models that directly estimate the prevalence ratio. BMC Med Res Methodol 2003; 3:21.
  • Pavord ID, Shaw D. The use of exhaled nitric oxide in the management of asthma. J Asthma 2008; 45(7):523–531.
  • Alving K, Weitzberg E, Lundberg JM. Increased amount of nitric oxide in exhaled air of asthmatics. Eur Respir J 1993; 6(9):1368–1370.
  • Kharitonov SA, Yates DH, Barnes PJ. Inhaled glucocorticoids decrease nitric oxide in exhaled air of asthmatic patients. Am J Respir Crit Care Med 1996; 153(1):454–457.
  • Smith AD, Cowan JO, Filsell S, McLachlan C, Monti-Sheehan G, Jackson P, Taylor DR. Diagnosing asthma: comparisons between exhaled nitric oxide measurements and conventional tests. Am J Respir Crit Care Med 2004; 169(4):473–478.
  • Malmberg LP, Pelkonen AS, Haahtela T, Turpeinen M. Exhaled nitric oxide rather than lung function distinguishes preschool children with probable asthma. Thorax 2003; 58(6):494–499.
  • Sivan Y, Gadish T, Fireman E, Soferman R. The use of exhaled nitric oxide in the diagnosis of asthma in school children. J Pediatr 2009; 155(2):211216.
  • Jones SL, Kittelson J, Cowan JO, Flannery EM, Hancox RJ, McLachlan CR, Taylor DR. The predictive value of exhaled nitric oxide measurements in assessing changes in asthma control. Am J Respir Crit Care Med 2001; 164(5):738–743.
  • Schatz M, Mosen D, Apter AJ, Zeiger RS, Vollmer WM, Stibolt TB, Leong A, Johnson MS, Mendoza G, Cook EF. Relationships among quality of life, severity, and control measures in asthma: an evaluation using factor analysis. J Allergy Clin Immunol 2005; 115(5):1049–1055.
  • Holt EW, Cook EF, Covar RA, Spahn J, Fuhlbrigge AL. Identifying the components of asthma health status in children with mild to moderate asthma. J Allergy Clin Immunol 2008; 121(5):1175–1180.
  • Leung TF, Wong GW, Ko FW, Lam CW, Fok TF. Clinical and atopic parameters and airway inflammatory markers in childhood asthma: a factor analysis. Thorax 2005; 60(10):822–826.
  • Gelb AF, Flynn TC, Shinar CM, Gutierrez C, Zamel N. Role of spirometry and exhaled nitric oxide to predict exacerbations in treated asthmatics. Chest 2006; 129(6):1492–1499.
  • Strunk RC, Szefler SJ, Phillips BR, Zeiger RS, Chinchilli VM, Larsen G, Hodgdon K, Morgan W, Sorkness CA, Lemanske RF. Jr. Relationship of exhaled nitric oxide to clinical and inflammatory markers of persistent asthma in children. J Allergy Clin Immunol 2003; 112(5):883–892.
  • Schroer B, Bossard M, Xu M, Lang D. Exhaled nitric oxide levels do not correlate with Asthma Control Test scores or spirometry in asthmatic patients. J Allergy Clin Immunol 2009; 123(2):S7.
  • Mahut B, Trinquart L, Le BM, Becquemin MH, Beydon N, Aubourg F, Jala M, Bidaud-Chevalier B, Dinh-Xuan AT, Randrianarivelo O, Denjean A, de Blic J, Delclaux C. Multicentre trial evaluating alveolar NO fraction as a marker of asthma control and severity. Allergy 2010; 65(5):636–644.
  • Shirai T, Furuhashi K, Suda T, Chika K. Relationship of the asthma control test with pulmonary function and exhaled nitric oxide. Ann Allergy Asthma Immuno 2008; 101:608–613.
  • Bernstein JA, Davis B, varez-Puebla MJ, Nguyen D, Levin L, Olaguibel JM. Is exhaled nitric oxide a useful adjunctive test for assessing asthma? J Asthma 2009; 46(9):955–960.
  • Zeiger RS, Szefler SJ, Phillips BR, Schatz M, Martinez FD, Chinchilli VM, Lemanske RF, Jr, Strunk RC, Larsen G, Spahn JD, Bacharier LB, Bloomberg GR, Guilbert TW, Heldt G, Morgan WJ, Moss MH, Sorkness CA, Taussig LM. Response profiles to fluticasone and montelukast in mild-to-moderate persistent childhood asthma. J Allergy Clin Immunol 2006; 117(1):45–52.
  • Schatz M, Zeiger RS, Drane A, Harden K, Cibildak A, Oosterman JE, Kosinski M. Reliability and predictive validity of the asthma control test administered by telephone calls using speech recognition technology. J Allergy Clin Immunol 2007; 119(2): 336–343.
  • Szefler SJ, Mitchell H, Sorkness CA, Gergen PJ, O'Connor GT, Morgan WJ, Kattan M, Pongracic JA, Teach SJ, Bloomberg GR, Eggleston PA, Gruchalla RS, Kercsmar CM, Liu AH, Wildfire JJ, Curry MD, Busse WW. Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: a randomised controlled trial. Lancet 2008; 372(9643):1065–1072.
  • Smith AD, Cowan JO, Brassett KP, Herbison GP, Taylor DR. Use of exhaled nitric oxide measurements to guide treatment in chronic asthma. N Engl J Med 2005; 352(21):2163–2173.
  • Dweik RA, Sorkness RL, Wenzel S, Hammel J, Curran-Everett D, Comhair SA, Bleecker E, Busse W, Calhoun WJ, Castro M, Chung KF, Israel E, Jarjour N, Moore W, Peters S, Teague G, Gaston B, Erzurum SC. Use of exhaled nitric oxide measurement to identify a reactive, at-risk phenotype among patients with asthma. Am J Respir Crit Care Med 2010; 181(10):1033–1041.
  • Perez-de-Llano LA, Carballada F, Castro AO, Pizarro M, Golpe R, Baloira A, Vazquez Caruncho M, Boquete M. Exhaled nitric oxide predicts control in patients with difficult-to-treat asthma. Eur Respir J 2010; 35(6):1221–1227.
  • Spergel JM, Fogg MI, Bokszczanin-Knosala A. Correlation of exhaled nitric oxide, spirometry and asthma symptoms. J Asthma 2005; 42(10):879–883.
  • Wang SW, Liu X, Wiener DJ, Sennett C, Bowers BW, Legorreta AP. Comparison of prevalence, cost, and outcomes of a combination of salmeterol and fluticasone therapy to common asthma treatments. Am J Manag Care 2001; 7(9):913–922.
  • Orsini L, Limpa-Amara S, Crown WH, Stanford RH, Kamal K. Asthma hospitalization risk and costs for patients treated with fluticasone propionate vs montelukast. Ann Allergy Asthma Immunol 2004; 92(5):523–529.
  • Diette GB, Patino CM, Merriman B, Paulin L, Riekert K, Okelo S, Patient factors that physicians use to assign asthma treatment. Arch Intern Med 2007; 167(13):1360–1366.
  • Okelo SO, Patino CM, Riekert KA, Merriman B, Bilderback A, Hansel NN, Thompson K, Thompson J, Quartey R, Rand CS. Patient factors used by pediatricians to assign asthma treatment. Pediatrics 2008; 122(1):e195–e201.

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