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Pharmacotherapy

Evaluation of Bedoradrine Sulfate (MN-221), a Novel, Highly Selective Beta2-Adrenergic Receptor Agonist for the Treatment of Asthma via Intravenous Infusion

, M.D., Ph.D., M.P.H., , Ph.D., , Ph.D. & , M.D., Ph.D.
Pages 1071-1078 | Published online: 25 Oct 2012

References

  • National Asthma Education and Prevention Program, National Heart Lung and Blood Institute, Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma, 2007. National Institutes of Health, Bethesda, MD.
  • National Center for Health Statistics Center for Disease Control NCHS CDC, 1996–2011.
  • Asthma mortality and hospitalization among children and young adults–United States, 1980–1993. Centers for Disease Control and Prevention (CDC). MMWR Morb Mortal Wkly Rep. 1996 May 3; 45(17):350–353.
  • Inoue Y, Yoshizato, T, Kawarabayashi T. Investigation of β2-adrenoceptor subtype selectivity and organ specificity for bedoradrine (KUR-1246), a novel tocolytic beta-adrenergic receptor stimulant. J. Obstet. Gynaecol. Res. 2009 Jun; 35(3):405–413.
  • MN-221 Investigator’s Brochure, MediciNova, Inc., Edition 6, July 15, 2010.
  • Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. This official statement of the American Thoracic Society was adopted by the ATS of Directors, November 1986. Am Rev Respir Dis 1987 Jul; 136(1):225–244.
  • Hankinson JL, Odencrantz JR, Fedan KB, Spirometric reference values from a sample of the general US population. Am J Respir Crit Care Med 1999 Jan; 159(1):179–187.
  • Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, van der Grinten CP, Gustafsson P, Jensen R, Johnson DC, Maclntyre N, McKary R, Navajas D, Pedersen OF, Pellegrino R, Viegi G, Wanger J; ATS/ERS Task Force. Standardisation of Spirometry. Eur Respir J 2005 Aug; 26(2): 319–336.
  • Ventolin Solution for IV Infusion. http://www.medicines.org.uk/EMC/printfriendlydocument.aspx?documentid=105&companyid=5
  • Guidance for Industry. E14 Clinical Evaluation of QT/QTc Interval Prolongation and Proarrhythmic Potential for Non-Antiarrhythmic Drugs. October 2005 (http://www.fda.gov/cber/gdlns/iche14qtc.pdf)

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