Th2 cytokine-primed airway smooth muscle cells induce mast cell chemotaxis via secretion of ATP

References

• Bradding P. Asthma: eosinophil disease, mast cell disease, or both? Allergy Asthma Clin Immunol 2008;4:84−90
   PubMedGoogle Scholar
• Krishnaswamy G, Kelley J, Johnson D, Youngberg G, Stone W, Huang SK, Bieber J, et al. The human mast cell: functions in physiology and disease. Front Biosci 2001;6:D1109−1127
   PubMed Web of Science ®Google Scholar
• Berger P, Girodet PO, Begueret H, Ousova O, Perng DW, Marthan R, Walls AF, et al. Tryptase-stimulated human airway smooth muscle cells induce cytokine synthesis and mast cell chemotaxis. FASEB J 2003;17:2139−2141
   PubMed Web of Science ®Google Scholar
• Page S, Ammit AJ, Black JL, Armour CL. Human mast cell and airway smooth muscle cell interactions: implications for asthma. Am J Physiol Lung Cell Mol Physiol 2001;281:L1313−1323
   Google Scholar
• Alkhouri H, Hollins F, Moir LM, Brightling CE, Armour CL, Hughes JM. Human lung mast cells modulate the functions of airway smooth muscle cells in asthma. Allergy 2011;66:1231−1241
   Google Scholar
• Bradding P, Brightling C. Mast cell infiltration of airway smooth muscle in asthma. Respir Med 2007;101:1045. Author reply 1046−1047
   Google Scholar
• Robinson DS. The role of the mast cell in asthma: induction of airway hyperresponsiveness by interaction with smooth muscle? J Allergy Clin Immunol 2004;114:58−65
   PubMed Web of Science ®Google Scholar
• Idzko M, Hammad H, van Nimwegen M, Kool M, Willart MA, Muskens F, Hoogsteden HC, et al. Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells. Nat Med 2007;13:913−919
   PubMed Web of Science ®Google Scholar
• Pelleg A, Schulman ES. Adenosine 5′-triphosphate axis in obstructive airway diseases. Am J Ther 2002;9:454−464
   Google Scholar
• Bours MJ, Swennen EL, Di Virgilio F, Cronstein BN, Dagnelie PC. Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther 2006;112:358−404
   PubMed Web of Science ®Google Scholar
• Weber FC, Esser PR, Muller T, Ganesan J, Pellegatti P, Simon MM, Zeiser R, et al. Lack of the purinergic receptor P2X(7) results in resistance to contact hypersensitivity. J Exp Med 2010;207:2609−2619
   PubMed Web of Science ®Google Scholar
• Yegutkin GG, Mikhailov A, Samburski SS, Jalkanen S. The detection of micromolar pericellular ATP pool on lymphocyte surface by using lymphoid ecto-adenylate kinase as intrinsic ATP sensor. Mol Biol Cell 2006;17:3378−3385
   PubMed Web of Science ®Google Scholar
• Liu L, Yang J, Huang Y. Human airway smooth muscle cells express eotaxin in response to signaling following mast cell contact. Respiration 2006;73:227−235
   Google Scholar
• Bulanova E, Bulfone-Paus S. P2 receptor-mediated signaling in mast cell biology. Purinergic Signal 2010;6:3−17
   PubMed Web of Science ®Google Scholar
• Borsellino G, Kleinewietfeld M, Di Mitri D, Sternjak A, Diamantini A, Giometto R, Hopner S, et al. Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression. Blood 2007;110:1225−1232
   PubMed Web of Science ®Google Scholar
• Deaglio S, Dwyer KM, Gao W, Friedman D, Usheva A, Erat A, Chen JF, et al. Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med 2007;204:1257−1265
   PubMed Web of Science ®Google Scholar
• Idzko M, Ayata CK, Muller T, Durk T, Grimm M, Baudiss K, Vieira RP, et al. Attenuated allergic airway inflammation in Cd39 null mice. Allergy 2013;68:472−480
   Google Scholar
• Olsson N, Rak S, Nilsson G. Demonstration of mast cell chemotactic activity in bronchoalveolar lavage fluid collected from asthmatic patients before and during pollen season. J Allergy Clin Immunol 2000;105:455−461
   Google Scholar
• Brightling CE, Ammit AJ, Kaur D, Black JL, Wardlaw AJ, Hughes JM, Bradding P. The CXCL10/CXCR3 axis mediates human lung mast cell migration to asthmatic airway smooth muscle. Am J Respir Crit Care Med 2005;171:1103−1108
   PubMedGoogle Scholar
• Brightling CE, Bradding P, Symon FA, Holgate ST, Wardlaw AJ, Pavord ID. Mast-cell infiltration of airway smooth muscle in asthma. N Engl J Med 2002;346:1699−1705
   PubMed Web of Science ®Google Scholar
• Brightling CE, Symon FA, Birring SS, Bradding P, Pavord ID, Wardlaw AJ. TH2 cytokine expression in bronchoalveolar lavage fluid T lymphocytes and bronchial submucosa is a feature of asthma and eosinophilic bronchitis. J Allergy Clin Immunol 2002;110:899−905
   Google Scholar
• Bradding P, Roberts JA, Britten KM, Montefort S, Djukanovic R, Mueller R, Heusser CH, et al. Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines. Am J Respir Cell Mol Biol 1994;10:471−480
   PubMed Web of Science ®Google Scholar
• Sanmugalingam D, Wardlaw AJ, Bradding P. Adhesion of human lung mast cells to bronchial epithelium: evidence for a novel carbohydrate-mediated mechanism. J Leukoc Biol 2000;68:38−46
   Google Scholar
• Miotto D, Christodoulopoulos P, Olivenstein R, Taha R, Cameron L, Tsicopoulos A, Tonnel AB, et al. Expression of IFN-gamma-inducible protein; monocyte chemotactic proteins 1, 3, and 4; and eotaxin in TH1- and TH2-mediated lung diseases. J Allergy Clin Immunol 2001;107:664−670
   PubMed Web of Science ®Google Scholar
• Hua X, Erikson CJ, Chason KD, Rosebrock CN, Deshpande DA, Penn RB, Tilley SL. Involvement of A1 adenosine receptors and neural pathways in adenosine-induced bronchoconstriction in mice. Am J Physiol Lung Cell Mol Physiol 2007;293:L25−32
   Google Scholar
• Juremalm M, Nilsson G. Chemokine receptor expression by mast cells. Chem Immunol Allergy 2005;87:130−144
   PubMedGoogle Scholar
• Brightling CE, Kaur D, Berger P, Morgan AJ, Wardlaw AJ, Bradding P. Differential expression of CCR3 and CXCR3 by human lung and bone marrow-derived mast cells: implications for tissue mast cell migration. J Leukoc Biol 2005;77:759−766
   PubMedGoogle Scholar
• Bochner BS, Hudson SA, Xiao HQ, Liu MC. Release of both CCR4-active and CXCR3-active chemokines during human allergic pulmonary late-phase reactions. J Allergy Clin Immunol 2003;112:930−934
   PubMed Web of Science ®Google Scholar
• Liu L, Jarjour NN, Busse WW, Kelly EA. Enhanced generation of helper T type 1 and 2 chemokines in allergen-induced asthma. Am J Respir Crit Care Med 2004;169:1118−1124
   Google Scholar
• Pilette C, Francis JN, Till SJ, Durham SR. CCR4 ligands are up-regulated in the airways of atopic asthmatics after segmental allergen challenge. Eur Respir J 2004;23:876−884
   PubMed Web of Science ®Google Scholar
• Woodman L, Sutcliffe A, Kaur D, Berry M, Bradding P, Pavord ID, Brightling CE. Chemokine concentrations and mast cell chemotactic activity in BAL fluid in patients with eosinophilic bronchitis and asthma, and in normal control subjects. Chest 2006;130:371−378
   Google Scholar
• Sutcliffe A, Kaur D, Page S, Woodman L, Armour CL, Baraket M, Bradding P, et al. Mast cell migration to Th2 stimulated airway smooth muscle from asthmatics. Thorax 2006;61:657−662
   Google Scholar
• Kaur D, Saunders R, Hollins F, Woodman L, Doe C, Siddiqui S, Bradding P, et al. Mast cell fibroblastoid differentiation mediated by airway smooth muscle in asthma. J Immunol 2010;185:6105−6114
   PubMed Web of Science ®Google Scholar