Salmeterol/fluticasone through breath-actuated inhaler versus pMDI: a randomized, double-blind, 12 weeks study

References

• GINA. Global Initiative for Asthma. Available from: http://www.ginasthma.org/local/uploads/files/GINA_Report_March13.pdf2011 [last accessed 6 Dec 2013]
   Google Scholar
• Rubin BK, Fink JB. Optimizing aerosol delivery by pressurized metered-dose inhalers. Respir Care 2005;50:1191–1197
   PubMedGoogle Scholar
• Newman SP. Principles of metered-dose inhaler design. Respir Care 2005;50:1177–1188
   PubMedGoogle Scholar
• Newman SP, Weisz AWB, Talaee N, Clarke SW. Improvement of drug delivery with a breath actuated pressurised aerosol for patients with poor inhaler technique. Thorax 1991;46:712–716
   PubMed Web of Science ®Google Scholar
• O'Callaghan C, Barry P. Spacer devices in the treatment of asthma. BMJ 1997;314:1061–1062
   PubMed Web of Science ®Google Scholar
• Newman SP. Spacer devices for metered dose inhalers. Clin Pharmacokinet 2004;43:349–360
   PubMed Web of Science ®Google Scholar
• Lavorini F, Fontana GA. Targeting drugs to the airways: the role of spacer devices. Expert Opin Drug Deliv 2009;6:91–102
   PubMed Web of Science ®Google Scholar
• Rau JL. Practical problems with aerosol therapy in COPD. Respir Care 2006;51:158–172
   PubMed Web of Science ®Google Scholar
• Laube BL, Janssens HM, Jongh FHC, Devadason SG, Dhand R, Diot P, Everard ML, et al. What the pulmonary specialist should know about the new inhalation therapies? Eur Respir J 2011;37:1308–1331
   PubMed Web of Science ®Google Scholar
• Giraud V, Allaert FA. Improved asthma control with breath-actuated pressurized Metered Dose Inhaler (pMDI): the SYSTER survey. Eur Rev Med Pharmacol Sci 2009;13:323–330
   PubMed Web of Science ®Google Scholar
• Molimard M, Raherison C, Lignot S, Depont F, Abouelfath A, Moore N. Assessment of handling of inhaler devices in real life: an observational study in 3811 patients in primary care. J Aerosol Med 2003;16:249–254
   PubMedGoogle Scholar
• Newman SP, Weisz AW, Talaee N, Clarke SW. Improvement of drug delivery with a breath actuated pressurised aerosol for patients with poor inhaler technique. Thorax 1991;46:712–716
   PubMed Web of Science ®Google Scholar
• Giraud V, Allaert FA. Improved asthma control with breath-actuated pressurized Metered Dose Inhaler (pMDI): the SYSTER survey. Eur Rev Med Pharmacol Sci 2009;13:323–330
   PubMed Web of Science ®Google Scholar
• Bateman ED, Boushey HA, Bousquet J, Busse WW, Clark TJH, Pauwels RA, Pedersen SE. Can guideline-defined asthma control be achieved? The gaining optimal asthma control study. Am J Respir Crit Care Med 2004;170:836–844
   PubMed Web of Science ®Google Scholar
• Woodcock AA, Bagdonas A, Boonsawat W, Gibbs MR, Bousquet J, Bateman ED. Improvement in asthma endpoints when aiming for total control: salmeterol/fluticasone propionate versus fluticasone propionate alone. Prim Care Respir J 2007;16:155–161
   PubMedGoogle Scholar
• Trautmann M, Banik N, Tews JT, Jorres RA, Nowak D. Efficacy of the combination of fluticasone propionate and salmeterol in patients with moderate persistent asthma within a “real-life” setting. Eur J Med Res 2007;12:255–263
   PubMed Web of Science ®Google Scholar
• Guidance for Industry E9 Statistical Principles for Clinical Trials. Available from: http://www.fda.gov/downloads/drugs/guidancecomplianceregulatoryinformation/guidances/ucm073137.pdf [last accessed 5 Mar 2015]
   Google Scholar
• Salvi S, Gogtay J, Aggarwal B. Use of breath-actuated inhalers in patients with asthma and COPD–an advance in inhalational therapy: a systematic review. Expert Rev Respir Med 2014;8:89–99
   PubMed Web of Science ®Google Scholar
• Lenney J, Innes JA, Crompton GK. Inappropriate inhaler use: assessment of use and patient preference of seven inhalation devices. Respir Med 2000;94:496–500
   PubMed Web of Science ®Google Scholar
• Peters SP, Ferguson G, Deniz Y, Reisner C. Uncontrolled asthma: a review of the prevalence, disease burden and options for treatment. Respir Med 2006;100:1139–1151
   PubMed Web of Science ®Google Scholar
• Peters SP, Jones CA, Haselkorn T, Mink DR, Valacer DJ, Weiss ST. Real-world Evaluation of Asthma Control and Treatment (REACT): findings from a national Web-based survey. J Allergy Clin Immunol 2007;119:1454–1461
   PubMed Web of Science ®Google Scholar
• Ryan D, Murphy A, Stallberg B, Baxter N, Heaney LG. “SIMPLES”: a structured primary care approach to adults with difficult asthma. Prim Care Respir J 2013;22:365–373
   PubMedGoogle Scholar
• Haughney J, Price D, Barnes NC, Virchow JC, Roche N, Chrystyn H. Choosing inhaler devices for people with asthma: current knowledge and outstanding research needs. Respir Med 2010;104:1237–1245
   PubMed Web of Science ®Google Scholar
• Bronsky EA, Debelic M, Pujet JC, Hahn M. Ease-of-use study of pirbuterol acetate in the Autohaler actuator in three countries: the United States, Germany, and France. J Asthma 1993;30:439–443
   PubMed Web of Science ®Google Scholar
• Price DB, Pearce L, Powell SR, Shirley J, Sayers MK. Handling and acceptability of the Easi-Breathe device compared with a conventional metered dose inhaler by patients and practice nurses. Int J Clin Pract 1999;53:31–36
   PubMed Web of Science ®Google Scholar