248
Views
11
CrossRef citations to date
0
Altmetric
Pathogenesis

Reduced clot retraction rate and altered platelet energy production in patients with asthma

, MD, PhD, , PhD, , PhD, , MD, PhD & , PhD
Pages 589-598 | Received 19 Aug 2015, Accepted 07 Dec 2015, Published online: 04 May 2016

References

  • Walford HH, Doherty TA. Diagnosis and management of eosinophilic asthma: a US perspective. J Asthma Allergy 2014;7:53–65. [ PMC][10.2147/JAA.S39119] [24748808]
  • Levy BD, Vachier I, Serhan CN. Resolution of inflammation in asthma. Clin Chest Med 2012;33:559–570. [ PMC][10.1016/j.ccm.2012.06.006] [22929102]
  • Reddy PH. Mitochondrial dysfunction and oxidative stress in asthma: implications for mitochondria-targeted antioxidant therapeutics. Pharmaceuticals (Basel) 2011;4:429–456. [ CrossRef][10.3390/ph4030429][ Mismatch]
  • Zuo L, Koozechian MS, Chen LL. Characterization of reactive nitrogen species in allergic asthma. Ann Allergy Asthma Immunol 2014;112:18–22. [ PMC][10.1016/j.anai.2013.10.007] [24331388]
  • Page C, Pitchford S. Platelets and allergic inflammation. Clin Exp Allergy 2014;44:901–913. [ PMC][10.1111/cea.12322] [24708345]
  • de Boer JD, Majoor CJ, van't Veer C, Bel EH, van der Poll T. Asthma and coagulation. Blood 2012;119:3236–3244. [ PMC][10.1182/blood-2011-11-391532] [22262775][ pubmedMismatch]
  • Majoor CJ, Kamphuisen PW, Zwinderman AH, Ten Brinke A, Amelink M, Rijssenbeek-Nouwens L, et al. Risk of deep vein thrombosis and pulmonary embolism in asthma. Eur Respir J 2013;42:655–661. [ CrossRef][10.1183/09031936.00150312][ Mismatch]
  • Chung WS, Lin CL, Ho FM, Li RY, Sung FC, Kao CH, Yeh JJ. Asthma increases pulmonary thromboembolism risk: a nationwide population cohort study. Eur Respir J 2014;43:801–807. [ PMC][10.1183/09031936.00043313] [23988762]
  • Somasundaram K, Ball J. Medical emergencies: pulmonary embolism and acute severe asthma. Anaesthesia 2013;68: 102–116. [ PMC][10.1111/anae.12051] [23210560]
  • Ono A, Westein E, Hsiao S, Nesbitt WS, Hamilton JR, Schoenwaelder SM, Jackson SP. Identification of a fibrin-independent platelet contractile mechanism regulating primary hemostasis and thrombus growth. Blood 2008;112:90–99. [ CrossRef][10.1182/blood-2007-12-127001]
  • Brass LF, Zhu L, Stalker TJ. Minding the gaps to promote thrombus growth and stability. J Clin Invest 2005;115:3385–3392. [ PMC][10.1172/JCI26869] [16322784]
  • de Witt SM, Verdoold R, Cosemans JM, Heemskerk JW. Insights into platelet-based control of coagulation. Thromb Res 2014;133: S139–148.
  • Collet JP, Montalescot G, Lesty C, Soria J, Mishal Z, Thomas D, Soria C. Disaggregation of in vitro preformed platelet-rich clots by abciximab increases fibrin exposure and promotes fibrinolysis. Arterioscler Thromb Vasc Biol 2001;21:142–148. [ CrossRef][10.1161/01.ATV.21.1.142]
  • Misztal T, Rusak T, Tomasiak M. Peroxynitrite may affect clot retraction in human blood through the inhibition of platelet mitochondrial energy production. Thromb Res 2014;133:402–411. [PMC][10.1016/j.thromres.2013.12.016] [24388569]
  • Misztal T, Przesław K, Rusak T, Tomasiak M. Peroxynitrite–altered platelet mitochondria–a new link between inflammation and hemostasis. Thromb Res 2013;131:e17–25.
  • Misztal T, Rusak T, Tomasiak M. Clinically relevant HOCl concentrations reduce clot retraction rate via the inhibition of energy production in platelet mitochondria. Free Radic Res 2014;48:1443–1453. [ PMC][10.3109/10715762.2014.960866] [25236568]
  • Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention 2012. GINA report. Available from: http://www.ginasthma.org/documents/5/documents_variants/37 [last accessed 18 December 2014].
  • Beg MF, Alzoghaibi MA, Abba AA, Habib SS. Exhaled nitric oxide in stable chronic obstructive pulmonary disease. Ann Thorac Med 2009;4:65–70.
  • Delclaux C, Mahut B, Zerah-Lancner F, Delacourt C, Laoud S, Cherqui D, Duvoux C, et al. Increased nitric oxide output from alveolar origin during liver cirrhosis versus bronchial source during asthma. Am J Respir Crit Care Med 2002;165:332–337.
  • American Thoracic Society; European Respiratory Society. ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005. Am J Respir Crit Care Med 2005;171:912–930.
  • Tomasiak-Lozowska MM, Zietkowski Z, Przeslaw K, Tomasiak M, Skiepko R, Bodzenta-Lukaszyk A. Inflammatory markers and acid-base equilibrium in exhaled breath condensate of stable and unstable asthma patients. Int Arch Allergy Immunol 2012;159:121–129. [ CrossRef][10.1159/000335674]
  • Osdoit S, Rosa JP. Fibrin clot retraction by human platelets correlates with alpha(IIb)beta(3) integrin-dependent protein tyrosine dephosphorylation. J Biol Chem 2001;276:6703–6710. [ PMC][10.1074/jbc.M008945200] [11084040]
  • Gutmann I, Wahlefeld AW. L(+) lactate. Determination with lactate dehydrogenase and NAD. In: Bergmeyer HU (ed) Methods of Enzymatic Analysis, 2nd edn. Academic Press, New York; 1974: 1464–1468.
  • Salooja N, Perry D. Thrombelastography. Blood Coagul Fibrinolysis 2001;12:327–337. [ PMC][11505075][ pubmedMismatch]
  • Zambruni A, Thalheimer U, Leandro G, Perry D, Burroughs A. Thromboelastography with citrated blood: comparability with native blood, stability of citrate storage and effect of repeated sampling. Blood Coagul Fibrinolysis 2004;15:103–107. [ CrossRef][10.1097/00001721-200401000-00017][ Mismatch]
  • Sørensen B, Johansen P, Christiansen K, Woelke M, Ingerslev J. Whole blood coagulation thrombelastographic profiles employing minimal tissue factor activation. J Thromb Haemost 2003;1:551–558. [ CrossRef][10.1046/j.1538-7836.2003.00075.x][ Mismatch]
  • Mürer EH. Clot retraction and energy metabolism of platelets. Effect and mechanism of inhibitors. Biochim Biophys Acta 1969;172:266–276. [ PMC][5775696]
  • Brand MD, Nicholls DG. Assessing mitochondrial dysfunction in cells. Biochem J 2011;435:297–312. [ PMC][10.1042/BJ20110162] [21726199]
  • Johannesdottir SA, Horváth-Puhó E, Dekkers OM, Cannegieter SC, Jørgensen JO, Ehrenstein V, Vandenbroucke JP, et al. Use of glucocorticoids and risk of venous thromboembolism: a nationwide population-based case-control study. JAMA Intern Med 2013;173:743–752. [ PMC][10.1001/jamainternmed.2013.122] [23546607][ pubmedMismatch]
  • Rose LJ, Dunn ME, Allegret V, Bédard C. Effect of prednisone administration on coagulation variables in healthy Beagle dogs. Vet Clin Pathol 2011;40:426–434. [ PMC][10.1111/j.1939-165X.2011.00364.x] [22093028]
  • Rusak T, Tomasiak M, Ciborowski M. Peroxynitrite can affect platelet responses by inhibiting energy production. Acta Biochim Pol 2006;53:769–776. [ PMC][17068635]
  • Saleh D, Ernst P, Lim S, Barnes PJ, Giaid A. Increased formation of the potent oxidant peroxynitrite in the airways of asthmatic patients is associated with induction of nitric oxide synthase: effect of inhaled glucocorticoid. FASEB J 1998;12:929–937.
  • Ricciardolo FL. Revisiting the role of exhaled nitric oxide in asthma. Curr Opin Pulm Med 2014;20:53–59. [ PMC][10.1097/MCP.0000000000000006][24275926][ pubmedMismatch]
  • Yamamoto M, Tochino Y, Chibana K, Trudeau JB, Holguin F, Wenzel SE. Nitric oxide and related enzymes in asthma: relation to severity, enzyme function and inflammation. Clin Exp Allergy 2012;42:760–768. [ CrossRef][10.1111/j.1365-2222.2011.03860.x]
  • Yang M, Kumar RK, Hansbro PM, Foster PS. Emerging roles of pulmonary macrophages in driving the development of severe asthma. J Leukoc Biol 2012;91:557–569. [ PMC][10.1189/jlb.0711357] [22293472]
  • Mita H, Higashi N, Taniguchi M, Higashi A, Kawagishi Y, Akiyama K. Urinary 3-bromotyrosine and 3-chlorotyrosine concentrations in asthmatic patients: lack of increase in 3-bromotyrosine concentration in urine and plasma proteins in aspirin-induced asthma after intravenous aspirin challenge. Clin Exp Allergy 2004;34:931–938. [ PMC][10.1111/j.1365-2222.2004.01968.x] [15196282]
  • Monteseirín J. Neutrophils and asthma. J Investig Allergol Clin Immunol 2009;19:340–354. [ PMC][19862934]
  • Klebanoff SJ, Kettle AJ, Rosen H, Winterbourn CC, Nauseef WM. Myeloperoxidase: a front-line defender against phagocytosed microorganisms. J Leukoc Biol 2013;93:185–198. [ PMC][10.1189/jlb.0712349] [23066164]
  • Buyukyilmaz G, Soyer OU, Buyuktiryaki B, Alioglu B, Dallar Y. Platelet aggregation, secretion, and coagulation changes in children with asthma. Blood Coagul Fibrinolysis 2014;25:738–744. [ CrossRef][10.1097/MBC.0000000000000136]
  • Olcay I, Yardımcı S, Delibası; T, Müftüoğlu O. Platelet functions in patients with allergic asthma. Turk J Hematol 2001;18:245–250.
  • Guppy M, Abas L, Arthur PG, Whisson ME. The Pasteur effect in human platelets: implications for storage and metabolic control. Br J Haematol 1995;91:752–757. [ PMC][8555088]
  • Tomasiak M, Stelmach H, Rusak T, Wysocka J. Nitric oxide and platelet energy metabolism. Acta Biochim Pol 2004;51:789–803. [ PMC][ 045103789][15448739]
  • Pacher P, Beckman JS, Liaudet L. Nitric oxide and peroxynitrite in health and disease. Physiol Rev 2007;87:315–424. [ PMC][10.1152/physrev.00029.2006] [17237348]
  • Cleeter MW, Cooper JM, Darley-Usmar VM, Moncada S, Schapira AH. Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide. Implications for neurodegenerative diseases. FEBS Lett 1994;345:50–54. [ PMC][8194600]
  • Brown GC. Regulation of mitochondrial respiration by nitric oxide inhibition of cytochrome c oxidase. Biochim Biophys Acta 2001;1504:46–57. [ PMC][11239484]
  • Humbert M, Menz G, Ying S, Corrigan CJ, Robinson DS, Durham SR, Kay AB. The immunopathology of extrinsic (atopic) and intrinsic (non-atopic) asthma: more similarities than differences. Immunol Today 1999;20:528–533. [ PMC][10529782]
  • Turato G, Barbato A, Baraldo S, Zanin ME, Bazzan E, Lokar-Oliani K, Calabrese F, et al. Nonatopic children with multitrigger wheezing have airway pathology comparable to atopic asthma. Am J Respir Crit Care Med 2008;178:476–482. [ PMC][10.1164/rccm.200712-1818OC] [18511700][ pubmedMismatch]
  • Nygaard G, Herfindal L, Kopperud R, Aragay AM, Holmsen H, Døskeland SO, Kleppe R, Selheim F. Time-dependent inhibitory effects of cGMP-analogues on thrombin-induced platelet-derived microparticles formation, platelet aggregation, and P-selectin expression. Biochem Biophys Res Commun 2014;449:357–363. [ PMC][10.1016/j.bbrc.2014.05.032] [24845383]
  • Mabalirajan U, Dinda AK, Kumar S, Roshan R, Gupta P, Sharma SK, Ghosh B. Mitochondrial structural changes and dysfunction are associated with experimental allergic asthma. J Immunol 2008;181:3540–3548. [ PMC][18714027]
  • Ho WE, Xu YJ, Cheng C, Peh HY, Tannenbaum SR, Wong WS, Ong CN. Metabolomics reveals inflammatory-linked pulmonary metabolic alterations in a murine model of house dust mite-induced allergic asthma. J Proteome Res 2014;13:3771–3782. [ CrossRef][10.1021/pr5003615]

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.