46
Views
8
CrossRef citations to date
0
Altmetric
Original Article

Nebulized Salbutamol (Albuterol): Systemic Absorption Could Be Important in Achieving Bronchodilatation

&
Pages 105-107 | Published online: 02 Jul 2009

References

  • Anonymous. Acute asthma. Lancet 1986; 1: 131–132
  • Britton J, Hanley S P, Garrett H V, Hadfield J W, Tat-Tersfield A E. Dose related effects of salbutamol and ipratropium bromide on airway calibre and reactivity in subjects with asthma. Thorax 1988; 43: 300–305
  • Brain J D, Valberg P A. Deposition of aerosol in the respiratory tract. Am Rev Respir Dis 1979; 120: 1325–1373
  • Shenfield C M, Evans M E, Paterson J W. The effect of different nebulizers with and without intermittent positive pressure breathing on the absorption and metabolism of salbutamol. Br. J Clin Pharamcol 1974; 1: 295–300
  • Borgstrom L, Nilsson M. A method for determination of the absolute pulmonary bioavialability of inhaled drugs: terbutaline. Pharmaceut Res 1990; 7: 1068–1070
  • Fuglsang G, Pedersen S, Borgstrom L. Dose response relationships of intravenously administered terbutaline in children with asthma. J Pediatr 1989; 114: 315–320
  • Morgan D J. Clinical pharmacokinetics of β agonists. Clin Pharmacokinet 1990; 18: 270–294
  • Lewis L D, McLaren M, Essex E, Cochrane G M. Plasma concentrations of salbutamol in acute severe asthmatics. Aust NZ Med 1990; 20: 204–207
  • Milroy R, Carter R, Carlyle D, Boyd G. Clinical and pharmacological study of a novel controlled release preparation of salbutamol. Br J Clin Pharmacol 1990; 29: 578–580
  • Lipworth B J, Clark R A, Dhillon D P, Charter M K, Palmer J BD, McDevitt D G. Single dose and steady-state pharmacokinetics of 4 mg and 8 mg oral salbutamol controlled-release in patients with bronchial asthma. Eur J Clin Pharmacol 1989; 37: 49–52
  • Bohn D, Kalloghlian A, Jenkins J, Edmonds J, Barker G. Intravenous salbutamol in the treatment of status asthmaticus in children. Crit Care Med 1984; 12: 892–896
  • Colacone A, Wolkove N, Stern E, Afilalo N, Rosenthal T M, Kreisman H. Continuous nebulization of albuterol (Salbutamol) in acute asthma. Chest 1990; 97: 693–697
  • Schuh S, Parkin P, Rajan A, Canny G, Healy R, Rieder M, Tan Y, Levison H, Soldin S. High versus low-dose, frequently administered, nebulised albuterol in children with severe, acute asthma. Pediatrics 1989; 83: 513–518
  • Schuh S, Reider M J, Canny G, Pender E, Forbes T, Tan Y K, Bailey D, Levison H. Nebulised albuterol in acute childhood asthma: comparison of two doses. Pediatrics 1990; 86: 509–513
  • Cheong B, Reynolds S R, Rajan G, Ward M J. Intravenous beta agonist in severe acute asthma. Br Med J 1988; 2: 448–450
  • Swedish Society of Chest Medicine. High-dose inhaled versus intravenous salbutamol combined with theophylline in severe acute asthma. Eur Respir J 1990; 3: 163–170
  • O'Driscoll B RC, Cochrane G M. Emergency use of nebulized bronchodilator in British hospitals. Thorax 1987; 42: 491–493
  • Janson C. Plasma levels and effects of salbutamol after inhaled or i. v. administration in stable asthma. Eur Respir J 1991; 4: 544–550

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.