192
Views
7
CrossRef citations to date
0
Altmetric
Original Article

Dna Damage Induction by 125I-Estrogen

, &
Pages 841-847 | Received 07 Sep 1995, Accepted 29 Feb 1996, Published online: 08 Jul 2009

References

  • DeSombre E. R. Steroid receptors in breast cancer. The Breast, R. W. McDivitt, H. A. Oberman, L. Ozzello, N. Kaufman. Williams and Wilkins, Baltimore 1984; 149–84
  • Clarke R., Lippman M. E., Dickson R. B. Mechanisms of hormone and cytotoxic drug interactions in the development and treatment of breast cancer. Molecular endocrinology and steroid hormone action, G. H. Sato, J. L. Stevens. Alan R. Liss, Inc. 1990; 243–78
  • DeSombre E. R., Harper P. V., Hughes A., et al. Bromine-80m radiotoxicity: Potential for estrogen receptor-directed therapy with Auger electrons. Cancer Res 1988; 48: 5805–9
  • DeSombre E. R., Mease R. C., Hughes A., Harper P. V., Dejesus O. T., Friedman A. M. Bromine-80m-labeled estrogens: Auger-electron emitting estrogen receptor-directed ligands with potential for therapy of estrogen receptor positive cancers. Cancer Res 1988; 48: 899–906
  • Bronzert D. A., Hochberg R. B., Lippman M. E. Specific cytotoxicity of 16α[125l]iodo-estradiol for estrogen receptor-containing breast cancer cells. Endocrinology 1982; 110: 2177–9
  • McLaughlin W. H., Milius R. A., Pillai K. M. R., Edasery J. P., Blu-Menthal RD, Bloomer W. D. Cytotoxicity of receptor-mediated 16α-125I-iodoestradiol in cultured MCF-7 human breast cancer cells. J Natl Cancer Inst 1989; 81: 437–40
  • Beckmann M. W., Scharl A., Rosinsky B. J., Holt J. A. Breaks in DNA accompany estrogen receptor-mediated cytotoxicity from 16α[125I]iodo-17β-estradiol. J Cancer Clin Oncol 1993; 119: 207–14
  • Kushner P. J., Hort E., Shine J., Baxter J. D., Greene G. L. Construction of cell lines that express high levels of the human estrogen receptor and are killed by estrogens. Mol Endocrinol 1990; 4: 1465–73
  • DeSombre E. R., Hughes A., Shafii B., et al. Estrogen receptor-directed radiotoxicity with Auger electrons-emitting nuclides: E-17α-[123I]iodovinyl-llβ-methoxyestradiol and CHO-ER cells. In: Biophysical aspects of Auger processes. AAPM Symposium Series 1992; 8: 352–71
  • Kohn K. W., Ewig R. A. G., Erickson L. C., Zwelling L. A. DNA repair: A laboratory manual of research procedures, E. C. Friedberg, P. C. Hanawalt. Marcel Dekker. Inc., New York 1981; 1, (part B)
  • Bradley M. O., Kohn K. W. X-ray induced DNA strand breaks production and repair in mammalian cells as measured by neutral filter elution. Nucleic Acids Res 1979; 7: 793–804
  • Flick M. B., Warters R. L., Yasui L. S., Krisch R. E. Measurements of radiation induced DNA damage using gel electrophoresis or neutral filter elution shows an increased frequency of DNA strand breaks after exposure to pH 9.6. Radiat Res 1989; 119: 452–65
  • Yasui L. S. Nuclear lesions produced by 125I decay. In: Biophysical aspects of Auger processes. AAPM Symposium Series 1992; 8: 210–26
  • Lippman M. E., Do H. M. T., Hochberg R. B. Specific estrogen receptor binding and biological effects of 16α-iodoestradiol on human breast cancer cells. Cancer Res 1981; 41: 3150–4
  • Kassis Al, Van den Abbeele A. D., Wen P. Y. C., et al. Specific uptake of the Auger electron-emitting thymidine analogue 5-[123I/125I]Iodo-2'-deoxyiarictine in rat brain tumors: Diagnostic and therapeutic implications in humans. Cancer Res 1990; 50: 199–203
  • Schwabe J. W. R., Chapman L., Finch F. T., Rhodes D. The crystal structure of the estrogen receptor DNA-binding domain bound to DNA. How receptors discriminate between their response elements. Cell 1993; 75: 567–78
  • Sundell-Bergman S., Johanson K. J. Impaired repair capacity of DNA strand breaks induced by 125I-triiodothyronine in Chinese hamster cells. Biochem Biophys Res Commun 1982; 106: 546–52
  • Evans R. M. The steroid and thyroid hormone receptor super-family. Science 1988; 240: 889–95
  • Murray V., Martin R. F. Sequence specificity of 125I-labelled Hoechst 33258 in intact human cells. J Mol Biol 1988; 210: 437–42
  • Murray V., Martin R. F. Sequence specificity of 125I-labelled Hoechst 33258 damage in six closely related DNA sequences. J Mol Biol 1988; 203: 63–73
  • Panyutin Ig, Neumann R. D. Sequence-specific DNA double-strand breaks induced by triplex forming 125l labeled oligonucleotides. Nucleic Acids Res 1994; 22: 4979–82

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.