1,324
Views
39
CrossRef citations to date
0
Altmetric
Research Article

Clinical Phase I study with an Insulin-like Growth Factor-1 Receptor Inhibitor: Experiences in patients with squamous non-small cell lung carcinoma

, , , , , , , , & show all
Pages 441-447 | Received 23 Feb 2010, Accepted 03 Jun 2010, Published online: 11 Aug 2010

References

  • Pollak M. Insulin and insulin-like growth factor signalling in neoplasia. Nat Rev Cancer 2008;8:915–28.
  • Gualberto A, Pollak M. Clinical development of inhibitors of the insulin-like growth factor receptor in oncology. Curr Drug Targets 2009;10:923–36.
  • Gualberto A, Pollak M. Emerging role of insulin-like growth factor receptor inhibitors in oncology: Early clinical trial results and future directions. Oncogene 2009;28:3009–21.
  • Girnita A, Girnita L, del Prete F, Bartolazzi A, Larsson O, Axelson M. Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth. Cancer Res 2004;64:236–42.
  • Stromberg T, Ekman S, Girnita L, Dimberg LY, Larsson O, Axelson M, . IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells. Blood 2006;107:669–78.
  • Yin S, Girnita A, Stromberg T, Khan Z, Andersson S, Zheng H, . Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma. Neuro Oncol 2010;12:19–27.
  • Crabb SJ, Patsios D, Sauerbrei E, Ellis PM, Arnold A, Goss G, . Tumor cavitation: Impact on objective response evaluation in trials of angiogenesis inhibitors in non-small-cell lung cancer. J Clin Oncol 2009;27:404–10.
  • Hatzidaki D, Agelaki S, Mavroudis D, Vlachonikolis I, Alegakis A, Georgoulias V; Lung Cancer Group of the Hellenic Oncology Research Group. A retrospective analysis of second-line chemotherapy or best supportive care in patients with advanced-stage non-small-cell lung cancer. Clin Lung Cancer 2006;1:49–55.
  • Bedano PM, Hanna N. Salvage therapy in patients with advanced non-small cell lung cancer. J Thorac Oncol 2006;6:582–7.
  • Karp DD, Paz-Ares L, Novello S, Haluska P, Garland L, Cardenal F, . High activity of the anti-IGF-IR antibody CP-751,871 in combination with paclitaxel and carboplatin in squamous NSCLC. ASCO Meeting Abstracts 2008;15 (Suppl):8015.
  • Kobayashi M, Okamoto K, Nakatani H, Okabayashi T, Namikawa T, Ichikawa K, . Complete remission of recurrent gastrointestinal stromal tumors after treatment with imatinib: Report of a case. Surg Today 2006;36:727–32.
  • Hong X, Choi H, Loyer EM, Benjamin RS, Trent JC, Charnsangavej C. Gastrointestinal stromal tumor: Role of CT in diagnosis and in response evaluation and surveillance after treatment with imatinib. Radiographics 2006;26:481–95.
  • Van den Abbeele AD. The lessons of GIST-PET and PET/CT: A new paradigm for imaging. Oncologist 2008;13:8–13.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.