1,480
Views
18
CrossRef citations to date
0
Altmetric
Review Article

Avoiding radical surgery after pre-operative chemoradiotherapy: A possible therapeutic option in rectal cancer?

, , &
Pages 275-284 | Received 04 Jul 2011, Accepted 18 Oct 2011, Published online: 07 Dec 2011

References

  • Ceelen WP, Van Nieuwenhove Y, Fierens K. Preoperative chemoradiation versus radiation alone for stage II and III resectable rectal cancer. Cochrane Database Syst Rev 2009; CD006041.
  • Bujko K, Nowacki MP, Nasierowska-Guttmejer A, Michalski W, Bebenek M, Kryj M. Long-term results of a randomized trial comparing preoperative short-course radiotherapy with preoperative conventionally fractionated chemoradiation for rectal cancer. Br J Surg 2006;93:1215–23.
  • Bosset JF, Collette L, Calais G, Mineur L, Maingon P, Radosevic-Jelic L, . EORTC Radiotherapy Group Trial 22921. Chemotherapy with preoperative radiotherapy in rectal cancer. New Eng J Med 2006;355:1114–23.
  • Marks G, Mohiuddin MM, Masoni L, Pecchioli L. High-dose preoperative radiation and full-thickness local excision. A new option for patients with select cancers of the rectum. Dis Colon Rectum 1990;33:735–9.
  • Mohiuddin M, Marks G, Bannon J. High-dose preoperative radiation and full thickness local excision: A new option for selected T3 distal rectal cancers. Int J Radiat Oncol Biol Phys 1994;30:845–9.
  • Callender GG, Das P, Rodriguez-Bigas MA, Skibber JM, Crane CH, Krishnan S, . Local excision after preoperative chemoradiation results in an equivalent outcome to total mesorectal excision in selected patients with T3 rectal cancer. Ann Surg Oncol 2010;17:441.
  • Kundel Y, Brenner R, Purim O, Peled N, Idelevich E, Fenig E, . Isocal excision after complete pathological response to neoadjuvant chemoradiation for rectal cancer an acceptable treatment option?. Dis Colon Rectum 2010; 53:1624–31.
  • Schell SR, Zlotecki RA, Mendenhall WM, Marsh RW Vauthey JN, Copeland EM 3rd., . Transanal excision of locally advanced rectal cancers downstaged using neoadjuvant chemoradiotherapy. J Am Coll Surg 2002;194:584.
  • Ruo L, Guillem JG, Minsky BD, Quan SH, Paty PB, Cohen AM. Preoperative radiation with or without chemotherapy and full-thickness transanal excision for selected T2 and T3 distal rectal cancers. Int J Colorectal Dis 2002;17:54.
  • Kim CJ, Yeatman TJ, Coppola D, Trotti A, Williams B, Barthel JS, . Local excision of T2 and T3 rectal cancers after downstaging chemoradiation. Ann Surg 2001;234:352.
  • Bonnen M, Crane C, Vauthey JN, Skibber J, Delclos ME, Rodriguez-Bigas M, . Long-term results using local excision after preoperative chemoradiation among selected T3 rectal cancer patients. Int J Radiat Oncol Biol Phys 2004; 60:1098.
  • Huh JW, Jung EJ, Park YA, Lee KY, Sohn SK. Preoperative chemoradiation followed by transanal excision for rectal cancer. J Surg Res 2008;148:244–50.
  • Nair RM, Siegel EM, Chen DT, Fulp WJ, Yeatman TJ, Malafa MP, . Long-term results of transanal excision after neoadjuvant chemoradiation for T2 and T3 adenocarcinomas of the rectum. J Gastrointest Surg 2008;12:1797–805; discussion 1805–6. Epub 2008 Aug 15.
  • Borschitz T, Wachtlin D, Möhler M, Schmidberger H, Junginger T. Neoadjuvant chemoradiation and local excision for T2-3 rectal cancer. Ann Surg Oncol 2008;15:712.
  • Guerrieri M, Baldarelli M, Organetti L, Grillo Ruggeri F, Mantello G, Bartolacci S, . Transanal endoscopic microsurgery for the treatment of selected patients with distal rectal cancer: 15 years experience. Surg Endosc 2008; 22:2030–5.
  • Lezoche G, Baldarelli M, Guerrieri M, Paganini AM, De Sanctis A, Bartolacci S, . A prospective randomized study with a 5-year minimum follow-up evaluation of transanal endoscopic microsurgery versus laparoscopic total mesorectal excision after neoadjuvant therapy. Surg Endosc 2008;22:352–8.
  • Bujko K, Richter P, Kołodziejczyk M, Nowacki MP, Kulig J, Popiela T, . Polish Colorectal Study Group. Preoperative radiotherapy and local excision of rectal cancer with immediate radical re-operation for poor responders. Radiother Oncol 2009;92:195–201. Epub 2009 Mar 16.
  • de Campos-Lobato LF, Stocchi L, da Luz Moreira A, Geisler D, Dietz DW, Lavery IC, . Pathologic complete response after neoadjuvant treatment for rectal cancer decreases distant recurrence and could eradicate local recurrence. Ann Surg Oncol Epub 2011 Jan 5.
  • Habr-Gama A, Perez RO, Nadalin W, Sabbaga J, Ribeiro U Jr, Silva e Sousa AH Jr, . Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: Long-term results. Ann Surg 2004;240:711.
  • Habr-Gama A. Assessment and management of the complete clinical response of rectal cancer to chemoradiotherapy. Colorectal Dis 2006;8(Suppl 3):21.
  • Habr-Gama A, Perez RO, Proscurshim I, Campos FG, Nadalin W, Kiss D, . Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy. J Gastrointest Surg 2006;10:1319–28; discussion 1328–9.
  • Hughes R, Harrison M, Glynne-Jones R. Could a wait and see policy be justified in T3/4 rectal cancers after chemo-radiotherapy?. Acta Oncol 2010;49:378–81.
  • Winde G, Nottberg H, Keller R, Schmid KW, Bünte H. Surgical cure for early rectal carcinomas (T1). Transanal endoscopic microsurgery vs. anterior resection. Dis Colon Rectum 1996;39:969–76.
  • Mignanelli ED, de Campos-Lobato LF, Stocchi L, Lavery IC, Dietz DW. Downstaging after chemoradiotherapy for locally advanced rectal cancer: Is there more (tumor) than meets the eye?. Dis Colon Rectum 2010;53:251–6.
  • Bedrosian I, Rodriquez-Bigas MA, Feig B, Hunt KK, Ellis L, Curley SA, . Predicting the node-negative mesorectum after preoperative chemoradiation for locally advanced rectal carcinoma. J Gastrointest Surg 2004;8:56–63.
  • Guillem J, Chessin D, Shia J, Moore HG, Mazumdar M, Bernard B, . Clinical examination following preoperative chemoradiation for rectal cancer is not a reliable surrogate end point. J Clin Oncol 2005;23:3475–9.
  • Hiotis SP, Weber SM, Cohen AM, Minsky BD, Paty PB, Guillem JG, . Assessing the predictive value of clinical complete response to neoadjuvant therapy for rectal cancer: An analysis of 488 patients. J Am Coll Surg 2002;194:131.
  • dos Santos LV, dos Anjos Jácome AA, Cárcano FM, da Silveira Nogueira Lima JP, Serrano SV. Watch and wait policy remains experimental for the management of rectal cancer. Colorectal Dis 2010;12:833.
  • Kalady MF, de Campos-Lobato LF, Stocchi L, Geisler DP, Dietz D, Lavery IC, . Predictive factors of pathologic complete response after neoadjuvant chemoradiation for rectal cancer. Ann Surg Epub 2009 Aug 25.
  • Habr-Gama A, Perez RO, Proscurshim I, Nunes Dos Santos RM, Kiss D, Gama-Rodrigues J, . Interval between surgery and neoadjuvant chemoradiation therapy for distal rectal cancer: Does delayed surgery have an impact on outcome?. Int J Radiat Oncol Biol Phys 2008;71:1181–8.
  • Garcia-Aguilar J, Smith DD, Avila K, Bergsland EK, Chu P, Krieg RM. Optimal timing of surgery after chemoradiation for advanced rectal cancer: Preliminary results of a multicenter, nonrandomized phase II prospective trial. Ann Surg 2011;254:97–102.
  • Hopkins S, Fakih M, Yang GY. Positron emission tomography as predictor of rectal cancer response during or following neoadjuvant chemoradiation. World J Gastrointest Oncol 2010;2:213–7.
  • Capirci C, Rubello D, Chierichetti F, Crepaldi G, Carpi A, Nicolini A, . Restaging after neoadjuvant chemoradiotherapy for rectal adenocarcinoma: Role of F18-FDG PET. Biomed Pharmacother 2004;58:451–7.
  • Barbaro B, Fiorucci C, Tebala C, Valentini V, Gambacorta MA, Vecchio FM, . Locally advanced rectal cancer: MR imaging in prediction of response after preoperative chemotherapy and radiation therapy. Radiology 2009;250:730–9.
  • Mardor Y, Roth Y, Ochershvilli A, Spiegelmann R, Tichler T, Daniels D, . Pretreatment prediction of brain tumors’ response to radiation therapy using high b-value diffusion-weighted MRI. Neoplasia 2004;6:136–42.
  • Sun YS, Zhang XP, Tang L, Ji JF, Gu J, Cai Y, . Locally advanced rectal carcinoma treated with preoperative chemotherapy and radiation therapy: Preliminary analysis of diffusion-weighted MR imaging for early detection of tumor histopathologic downstaging. Radiology 2010;254:170–8. Epub 2009 Dec 17.
  • Capirci C, Rubello D, Chierichetti F, Crepaldi G, Fanti S, Mandoliti G, . Long-term prognostic value of 18F-FDG PET in patients with locally advanced rectal cancer previously treated with neoadjuvant radiochemotherapy. AJR Am J Roentgenol 2006;187:W202–8.
  • Capirci C, Rampin L, Erba PA, Galeotti F, Crepaldi G, Banti E, . Sequential FDG-PET/CT reliably predicts response of locally advanced rectal cancer to neo-adjuvant chemo-radiation therapy. Eur J Nucl Med Mol Imaging 2007;34:1583–93.
  • Amthauer H, Denecke T, Rau B, Hildebrandt B, Hünerbein M, Ruf J, . Response prediction by FDG-PET after neoadjuvant radiochemotherapy and combined regional hyperthermia of rectal cancer: Correlation with endorectal ultrasound and histopathology. Eur J Nucl Med Mol Imaging 2004;31:811–9.
  • Rosenberg R, Herrmann K, Gertler R, Künzli B, Essler M, Lordick F, . The predictive value of metabolic response to preoperative radiochemotherapy in locally advanced rectal cancer measured by PET/CT. Int J Colorectal Dis 2009; 24:191–200.
  • Konski A, Li T, Sigurdson E, Cohen SJ, Small W Jr, Spies S, . Use of molecular imaging to predict clinical outcome in patients with rectal cancer after preoperative chemotherapy and radiation. Int J Radiat Oncol Biol Phys 2009;74:55–9.
  • Janssen MH, Ollers MC, van Stiphout RG, Riedl RG, van den Bogaard J, Buijsen J, . PET-based treatment response evaluation in rectal cancer: Prediction and validation. Int J Radiat Oncol Biol Phys Epub 2011 Mar 5.
  • Lambrecht M, Deroose C, Roels S, Vandecaveye V, Penninckx F, Sagaert X, . The use of FDG-PET/CT and diffusion-weighted magnetic resonance imaging for response prediction before, during and after preoperative chemoradiotherapy for rectal cancer. Acta Oncol 2010;49:956–63.
  • Wlodkowic D, Cooper JM. Tumors on chips; oncology meets microfluidics. Curr Op Chem Biol 2010;14:1–12.
  • Webster A, Greenman J, Haswell SJ. Development of microfluidic devices for biomedical and clinical application. J Chem Technol Biotechnol 2010. DOI 10.1002/jctb.2482.
  • Webster A, Dyer CE, Haswell SJ, Greenman J. A microfluidic device for tissue biopsy culture and interrogation. Anal Methods 2010;2:1005–7.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.