74
Views
4
CrossRef citations to date
0
Altmetric
Research Article

Adherence of Staphylococcus epidermidis to human endothelial cells is associated with a polysaccharidic component of its extracellular mucous layer

, , , &
Pages 183-189 | Received 07 Apr 2010, Accepted 28 Jun 2010, Published online: 01 Oct 2010

REFERENCES

  • Bensing, B.A., López, J.A., and Sullam, P.M. (2004). The Streptococcus gordonii surface proteins GspB and Hsa mediate binding to sialylated carbohydrate epitopes on the platelet membrane glycoprotein Ibalpha. Infect. Immun. 72:6528–6537.
  • Chen, Q., Wu, H., and Fives-Taylor, P.M. (2004). Investigating the role of secA2 in secretion and glycosylation of a fimbrial adhesin in Streptococcus parasanguis FW213. Mol. Microbiol. 53:843–856.
  • Siboo, I.R., Chambers, H.F., and Sullam, P.M. (2005). Role of SraP, a serine-rich surface protein of Staphylococcus aureus, in binding to human platelets. Infect. Immun. 73:2273–2280.
  • Deivanayagam, C.C., Wann, E.R., Chen, W., Carson, M., Rajashankar, K.R., Höök, M., and Narayana, S.V. (2002). A novel variant of the immunoglobulin fold in surface adhesins of Staphylococcus aureus: Crystal structure of the fibrinogen-binding MSCRAMM, clumping factor A. EMBO J. 21:6660–6672.
  • Ganesh, V.K., Rivera, J.J., Smeds, E., Ko, Y.P., Bowden, M.G., Wann, E.R., Gurusiddappa, S., Fitzgerald, J.R., and Höök, M. (2008). A structural model of the Staphylococcus aureus ClfA-fibrinogen interaction opens new avenues for the design of anti-staphylococcal therapeutics. PLoS Pathog. 4:e1000226. Epub November 28, 2008.
  • Schröder, A., Schröder, B., Roppenser, B., Linder, S., Sinha, B., Fässler, R., and Aepfelbacher, M. (2006). Staphylococcus aureus fibronectin binding protein-A induces motile attachment sites and complex actin remodeling in living endothelial cells. Mol. Biol. Cell. 17:5198–5210.
  • Tompkins, D.C., Blackwell, L.J., Hatcher, V.B., Elliott, D.A., O'Hagan-Sotsky, C., and Lowy, F.D. (1992). Staphylococcus aureus proteins that bind to human endothelial cells. Infect. Immun. 60:965–969.
  • Sinha, B., François, P.P., Nüsse, O., Foti, M., Hartford, O.M., Vaudaux, P., Foster, T.J., Lew, D.P., Herrmann, M., and Krause, K.H. (1999). Fibronectin-binding protein acts as Staphylococcus aureus invasin via fibronectin bridging to integrin alpha5beta1. Cell. Microbiol. 1:101–117.
  • Massey, R.C., Kantzanou, M.N., Fowler, T., Day, N.P., Schofield, K., Wann, E.R., Berendt, A.R., Höök, M., and Peacock, S.J. (2001). Fibronectin-binding protein A of Staphylococcus aureus has multiple, substituting, binding regions that mediate adherence to fibronectin and invasion of endothelial cells. Cell. Microbiol. 3:839–851.
  • Flock, J.I. (1999). Extracellular-matrix-binding proteins as targets for the prevention of Staphylococcus aureus infections. Mol. Med. Today 5:532–537.
  • Fallgren, C., Andersson, A., and Ljungh, A. (2001). The role of glycosaminoglycan binding of staphylococci in attachment to eukaryotic host cells. Curr. Microbiol. 43:57–63.
  • Tacconelli, E., Tumbarello, M., Pittiruti, M., Leone, F., Lucia, M.B., Cauda, R., and Ortona, L. (1997). Central venous catheter-related sepsis in a cohort of 366 hospitalised patients. Eur. J. Clin. Microbiol. Infect. Dis. 16:203–209.
  • Raad, I., Alrahwan, A., and Rolston, K. (1998). Staphylococcus epidermidis: Emerging resistance and need for alternative agents. Clin. Infect. Dis. 26:1182–1187.
  • Mack, D., Fischer, W., Krokotsch, A., Leopold, K., Hartmann, R., Egge, H., and Laufs, R. (1996). The intercellular adhesin involved in biofilm accumulation of Staphylococcus epidermidis is a linear beta-1,6-linked glucosaminoglycan: Purification and structural analysis. J. Bacteriol. 178:175–183.
  • Tojo, M., Yamashita, N., Goldmann, D.A., and Pier, G.B. (1988). Isolation and characterization of a capsular polysaccharide adhesin from Staphylococcus epidermidis. J. Infect. Dis. 157:713–722. Erratum in: J. Infect. Dis. 158:268.
  • Maira-Litrán, T., Kropec, A., Abeygunawardana, C., Joyce, J., Mark, G. 3rd, Goldmann, D.A., and Pier, G.B. (2002). Immunochemical properties of the staphylococcal poly-N-acetylglucosamine surface polysaccharide. Infect. Immun. 70:4433–4440.
  • Arvaniti, A., Karamanos, N.K., Dimitracopoulos, G., and Anastassiou, E.D. (1994). Isolation and characterization of a novel 20-kDa sulfated polysaccharide from the extracellular slime layer of Staphylococcus epidermidis. Arch. Biochem. Biophys. 308:432–438.
  • Krevvata, M.I., Afratis, N., Spiliopoulou, A., Malavaki, C., Kolonitsiou, F., Anastassiou, E., and Karamanos, N.K. (2010). A modified protocol for isolation and purity evaluation of a staphylococcal acidic polysaccharide by chromatography and capillary electrophoresis. Biomed. Chromatog. [Under publication].
  • Karamanos, N.K., Syrokou, A., Panagiotopoulou, H.S., Anastassiou, E.D., and Dimitracopoulos, G. (1997). The major 20-kDa polysaccharide of Staphylococcus epidermidis extracellular slime and its antibodies as powerful agents for detecting antibodies in blood serum and differentiating among slime-positive and -negative S. epidermidis and other staphylococci species. Arch. Biochem. Biophys. 342:389–395.
  • Karamanos, N.K., Panagiotopoulou, H.S., Syrokou, A., Frangides, C., Hjerpe, A., Dimitracopoulos, G., and Anastassiou, E.D. (1995). Identity of macromolecules present in the extracellular slime layer of Staphylococcus epidermidis. Biochimie. 77:217–224.
  • Georgakopoulos, C.D., Exarchou, A., Koliopoulos, J.X., Gartaganis, S.P., Anastassiou, E.D., Kolonitsiou, F., Lamari, F., Karamanos, N.K., and Dimitracopoulos, G. (2002). Levels of specific antibodies towards the major antigenic determinant of slime-producing Staphylococcus epidermidis determined by an enzyme immunoassay and their protective effect in experimental keratitis. J. Pharm. Biomed. Anal. 29:255–262.
  • Merkel, G.J., and Scofield, B.A. (2001). Interaction of Staphylococcus epidermidis with endothelial cells in vitro. Med. Microbiol. Immunol. 189:217–223.
  • Costa, A.R., Henriques, M., Oliveira, R., and Azeredo, J. (2009). The role of polysaccharide intercellular adhesin (PIA) in Staphylococcus epidermidis adhesion to host tissues and subsequent antibiotic tolerance. Eur. J. Clin. Microbiol. Infect. Dis. 28:623–629.
  • Mack, D., Davies, A.P., Harris, L.G., Knobloch, J.K.M., and Rohde, H. (2009). Staphylococcus epidermidis biofilms: Functional molecules, relation to virulence, and vaccine potential. Top. Curr. Chem. 288:157–182.
  • Lamari, F., Anastassiou, E.D., Stamokosta, E., Photopoulos, S., Xanthou, M., Dimitracopoulos, G., and Karamanos, N.K. (2000). Determination of slime-producing S. epidermidis specific antibodies in human immunoglobulin preparations and blood sera by an enzyme immunoassay: Correlation of antibody titers with opsonic activity and application to preterm neonates. J. Pharm. Biomed. Anal. 23:363–374.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.