Age-Related Changes in the Cellular, Mechanical, and Contractile Properties of Rat Tail Tendons

References

• Kaux, J., Forthomme, B., Le Goff, C., Crielaard, J., and Croisier, J. (2011). Current opinions on tendinopathy. J. Sports Sci. Med. 10(2):238–253.
   PubMed Web of Science ®Google Scholar
• Bjornsson, H.C., Norlin, R., Johansson, K., and Adolfsson, L.E. (2011). The influence of age, delay of repair, and tendon involvement in acute rotator cuff tears: Structural and clinical outcomes after repair of 42 shoulders. Acta Orthop. 82(2):187–192.
   PubMed Web of Science ®Google Scholar
• Nho, S.J., Brown, B.S., Lyman, S., Adler, R.S., Altcheck, D.W., and MacGillivray, J.D. (2009). Prospective analysis of arthroscopic rotator cuff repair: Prognostic factors affecting clinical and ultrasound outcome. J. Shoulder Elbow Surg. 18(1):13–20.
   PubMed Web of Science ®Google Scholar
• Gage, B.E., McIlvain, N.M., Collins, C.L., Fields, S.K., and Comstock, R.D. (2012). Epidemiology of 6.6 million knee injuries presenting to United States emergency departments from 1999 through 2008. Acad. Emerg. Med. 19(4):378–385.
   PubMed Web of Science ®Google Scholar
• Kammerlander, C., Braito, M., Kates, S., Jeske, C., Roth, T., Blauth, M., and Dallapozza, C. (2012). The epidemiology of sports-related injuries in older adults: A Central European epidemiologic study. Aging Clin. Exp. Res. doi: 10.3275/8273. [Epub ahead of print].
   Google Scholar
• Arnoczky, S.P., Lavagnino, M., Egerbacher, M., Caballero, O., Gardner, K., and Shender, M.A. (2008). Loss of homeostatic strain alters mechanostat “set point” of tendon cells in vitro. Clin. Orthop. Relat. Res. 466(7):1583–1591.
   PubMed Web of Science ®Google Scholar
• Arnoczky, S.P., Tian, T., Lavagnino, M., and Gardner, K. (2004). Ex vivo static tensile loading inhibits MMP-1 expression in rat tail tendon cells through a cytoskeletally based mechanotransduction mechanism. J. Orthop. Res. 22(2):328–333.
   PubMed Web of Science ®Google Scholar
• Hannafin, J.A., Arnoczky, S.P., Hoonjan, A., and Torzilli, P.A. (1995). Effect of stress deprivation and cyclic tensile loading on the material and morphologic properties of canine flexor digitorum profundus tendon: An in vitro study. J. Orthop. Res. 13(6):907–914.
   PubMed Web of Science ®Google Scholar
• Lavagnino, M., and Arnoczky, S.P. (2005). In vitro alterations in cytoskeletal tensional homeostasis control gene expression in tendon cells. J. Orthop. Res. 23(5):1211–1218.
   PubMed Web of Science ®Google Scholar
• Lavagnino, M., Arnoczky, S.P., Egerbacher, M., Gardner, K.L., and Burns, M.E. (2006). Isolated fibrillar damage in tendons stimulates local collagenase mRNA expression and protein synthesis. J. Biomech. 39(13):2355–2362.
   PubMed Web of Science ®Google Scholar
• Lavagnino, M., Arnoczky, S.P., Tian, T., and Vaupel, Z. (2003). Effect of amplitude and frequency of cyclic tensile strain on the inhibition of MMP-1 mRNA expression in tendon cells: An in vitro study. Connect. Tissue Res. 44(3–4):181–187.
   PubMed Web of Science ®Google Scholar
• DuFort, C.C., Paszek, M.J., and Weaver, V.M. (2011). Balancing forces: Architectural control of mechanotransduction. Nat. Rev. Mol. Cell. Biol. 12(5):308–319.
   PubMed Web of Science ®Google Scholar
• Cheng, C., Tempel, D., van Haperen, R., van der Baan, A., Grosveld, F., Daemen, M.J., Krams, R., and de Crom, R. (2006). Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress. Circulation 113(23):2744–2753.
   PubMed Web of Science ®Google Scholar
• Klein-Nulend, J., Bacabac, R.G., Veldhuijzen, J.P., and Van Loon, J.J. (2003). Microgravity and bone cell mechanosensitivity. Adv. Space Res. 32(8):1551–1559.
   PubMed Web of Science ®Google Scholar
• Arnoczky, S.P., Lavagnino, M., and Egerbacher, M. (2007). The mechanobiological aetiopathogenesis of tendinopathy: Is it the over-stimulation or the under-stimulation of tendon cells? Int. J. Exp. Pathol. 88(4):217–226.
   PubMed Web of Science ®Google Scholar
• Egerbacher, M., Arnoczky, S.P., Caballero, O., Lavagnino, M., and Gardner, K. (2008). Loss of homeostatic tension induces apoptosis in tendon cells: An in vitro study. Clin. Orthop. Relat. Res. 466(7): 1562–1568.
   PubMed Web of Science ®Google Scholar
• Rigby, B.J. (1964). Effect of cyclic extension on the physical properties of tendon collagen and its possible relation to biological ageing of collagen. Nature 202:1072–1074.
   PubMed Web of Science ®Google Scholar
• King, G.J., Edwards, P., Brant, R.F., Shrive, N.G., and Frank, C.B. (1995). Intraoperative graft tensioning alters viscoelastic but not failure behaviours of rabbit medial collateral ligament autografts. J. Orthop. Res. 13(6):915–922.
   PubMed Web of Science ®Google Scholar
• Maquirriain, J. (2011). Achilles tendon rupture: Avoiding tendon lengthening during surgical repair and rehabilitation. Yale J. Biol. Med. 84(3):289–300.
   PubMedGoogle Scholar
• Crisco, J.J., Chelikani, S., Brown, R.K., and Wolfe, S.W. (1997). The effects of exercise on ligamentous stiffness in the wrist. J. Hand Surg. Am. 22(1):44–48.
   PubMedGoogle Scholar
• Dahners, L.E., Banes, A.J., and Burridge, K.W. (1986). The relationship of actin to ligament contraction. Clin. Orthop. Relat. Res. 210:246–251.
   PubMedGoogle Scholar
• Gardner, K., Lavagnino, M., Egerbacher, M., and Arnoczky, S.P. (2012). Re-establishment of cytoskeletal tensional homeostasis in lax tendons occurs through an actin-mediated cellular contraction of the extracellular matrix. J. Orthop. Res. 30(11):1695–1701.
   Google Scholar
• Squier, C.A., and Magnes, C. (1983). Spatial relationships between fibroblasts during the growth of rat-tail tendon. Cell Tissue Res. 234(1):17–29.
   PubMed Web of Science ®Google Scholar
• Farshad, M., Gerber, C., Snedeker, J.G., Frauenfelder, T., and Meyer, D.C. (2011). Structure of retracted tendons after staged repair following continuous traction. Knee Surg. Sports Traumatol. Arthrosc. 19(12): 2131–2137.
   PubMed Web of Science ®Google Scholar
• Meyer, D.C., Lajtai, G., von Rechenberg, B., Pfirrmann, C.W., and Gerber, C. (2006). Tendon retracts more than muscle in experimental chronic tears of the rotator cuff. J. Bone Joint Surg. Br. 88(11):1533–1538.
   PubMedGoogle Scholar
• Ippolito, E., Natali, P.G., Postacchini, F., Accinni, L., and De Martino, C. (1980). Morphological, immunochemical, and biochemical study of rabbit Achilles tendon at various ages. J. Bone Joint Surg. Am. 62(4): 583–598.
   PubMed Web of Science ®Google Scholar
• Nakagawa, Y., Majima, T., and Nagashima, K. (1994). Effect of ageing on ultrastructure of slow and fast skeletal muscle tendon in rabbit Achilles tendons. Acta Physiol. Scand. 152(3):307–313.
   PubMedGoogle Scholar
• Stanley, R.L., Fleck, R.A., Becker, D.L., Goodship, A.E., Ralphs, J.R., and Patterson-Kane, J.C. (2007). Gap junction protein expression and cellularity: Comparison of immature and adult equine digital tendons. J. Anat. 211(3):325–334.
   PubMed Web of Science ®Google Scholar
• Moore, M.J., and De Beaux, A. (1987). A quantitative ultrastructural study of rat tendon from birth to maturity. J. Anat. 153:163–169.
   PubMed Web of Science ®Google Scholar
• Diamant, J., Keller, A., Baer, E., Litt, M., and Arridge, R.G. (1972). Collagen: Ultrastructure and its relation to mechanical properties as a function of ageing. Proc. R. Soc. Lond. B Biol. Sci. 180(60):293–315.
   PubMed Web of Science ®Google Scholar
• Goh, K.L., Holmes, D.F., Lu, H.Y., Richardson, S., Kadler, K.E., Purslow, P.P., and Wess, T.J. (2008). Ageing changes in the tensile properties of tendons: Influence of collagen fibril volume fraction. J. Biomech. Eng. 130(2):021011.
   Web of Science ®Google Scholar
• Reihsner, R., Pfeiler, W., and Menzel, E.J. (1998). Comparison of normal and in vitro aging by non-enzymatic glycation as verified by differential scanning calorimetry. Gerontology 44(2):85–90.
   PubMed Web of Science ®Google Scholar
• Vogel, H.G. (1978). Influence of maturation and age on mechanical and biochemical parameters of connective tissue of various organs in the rat. Connect. Tissue Res. 6(3):161–166.
   PubMed Web of Science ®Google Scholar
• Nielsen, H.M., Skalicky, M., and Viidik, A. (1998). Influence of physical exercise on aging rats. III. Life-long exercise modifies the aging changes of the mechanical properties of limb muscle tendons. Mech. Ageing Dev. 100(3):243–260.
   PubMed Web of Science ®Google Scholar
• Eastwood, M., McGrouther, D.A., and Brown, R.A. (1994). A culture force monitor for measurement of contraction forces generated in human dermal fibroblast cultures: Evidence for cell-matrix mechanical signalling. Biochim. Biophys. Acta 1201(2):186–192.
   PubMed Web of Science ®Google Scholar
• Yeung, T., Georges, P.C., Flanagan, L.A., Marg, B., Ortiz, M., Funaki, M., Zahir, N., Ming, W., Weaver, V., and Janmey, P.A. (2005). Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion. Cell Motil. Cytoskeleton 60(1):24–34.
   PubMed Web of Science ®Google Scholar
• Reinhart-King, C.A. (2011). How matrix properties control the self-assembly and maintenance of tissues. Ann Biomed. Eng. 39(7):1849–1856.
   PubMed Web of Science ®Google Scholar
• Tan, J.L., Tien, J., Pirone, D.M., Gray, D.S., Bhadriraju, K., and Chen, C.S. (2003). Cells lying on a bed of microneedles: An approach to isolate mechanical force. Proc. Natl. Acad. Sci. USA 100(4):1484–1489.
   PubMed Web of Science ®Google Scholar
• Meller, R., Schiborra, F., Brandes, G., Knobloch, K., Tschernig, T., Hankemeier, S., Haasper, C., Schmiedl, A., Jagodzinski, M., Krettek, C., and Willbold, E. (2009). Postnatal maturation of tendon, cruciate ligament, meniscus and articular cartilage: A histological study in sheep. Ann Anat. 191(6):575–585.
   PubMed Web of Science ®Google Scholar
• Strocchi, R., De Pasquale, V., Guizzardi, S., Govoni, P., Facchini, A., Raspanti, M., Girolami, M., and Giannini, S. (1991). Human Achilles tendon: Morphological and morphometric variations as a function of age. Foot Ankle 12(2):100–104.
   PubMedGoogle Scholar
• Gillis, C., Sharkey, N., Stover, S.M., Pool, R.R., Meagher, D.M., and Willits, N. (1995). Effect of maturation and aging on material and ultrasonographic properties of equine superficial digital flexor tendon. Am. J. Vet. Res. 56(10):1345–1350.
   PubMed Web of Science ®Google Scholar
• Waugh, C.M., Blazevich, A.J., Fath, F., and Korff, T. (2012). Age-related changes in mechanical properties of the Achilles tendon. J. Anat. 220(2):144–155.
   PubMed Web of Science ®Google Scholar
• Haut, R.C. (1983). Age-dependent influence of strain rate on the tensile failure of rat-tail tendon. J. Biomech. Eng. 105(3):296–299.
   PubMed Web of Science ®Google Scholar
• Nagy, I.Z., Von Hahn, H.P., and Verzár, F. (1969). Age-related alterations in the cell nuclei and the DNA content of rat tail tendon. Gerontologia 15(4):258–264.
   PubMedGoogle Scholar