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ORIGINAL ARTICLE

Alpha-1-antitrypsin phenotypes in adult liver disease patients

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Pages 228-234 | Received 29 Jun 2009, Accepted 03 Aug 2009, Published online: 04 Dec 2009

References

  • American Thoracic Society; European Respiratory Society. American Thoracic Society/European Respiratory Society Statement: Standards for the diagnosis and management of individuals with alpha-1 antitrypsin deficiency. Am J Respir Crit Care Med. 2003;168:818–900.
  • Eriksson S, Carlson J, Velez R. Risk of cirrhosis and primary liver cancer in alpha1-antitrypsin deficiency. N Engl J Med. 1986;314:736–9.
  • Curiel DT, Chytil A, Courtney M, Crystal RG. Serum alpha 1-antitrypsin deficiency associated with the common S-type (Glu264→Val) mutation results from intracellular degradation of alpha 1-antitrypsin prior to secretion. J Biol Chem. 1989;264:10477–86.
  • Elliott PR, Stein PE, Bilton D, Carrell RW, Lomas DA. Structural explanation for the deficiency of S α1-antitrypsin. Nat Struct Biol. 1996;3:910–1.
  • Mahadeva R, Chang WS, Dafforn TR, Oakley DJ, Foreman RC, Calvin J, . Heteropolymerization of S, I, and Z α1-antitrypsin and liver cirrhosis. J Clin Invest. 1999;103:999–1006.
  • Tobin MJ, Cook PJ, Hutchinson DC. Alpha 1-antitrypsin deficiency: the clinical and physiological features of pulmonary emphysema in subjects homozygous for Pi type Z: a survey by the British Thoracic Association. Br J Dis Chest. 1983;77:14–27.
  • Brantly ML, Paul LD, Miller BH, Falk RT, Wu M, Crystal RG. Clinical features and history of the destructive lung disease associated with alpha-1-antitrypsin deficiency of adults with pulmonary symptoms. Am Rev Respir Dis. 1988;138:327–36.
  • Kishimoto Y, Yamada S, Hirayama C. An association between AAT phenotype and chronic liver disease. Hum Genet. 1990;84:132–6.
  • Sveger T. Liver disease in alpha1-antitrypsin deficiency detected by screening of 200,000 infants. N Engl J Med. 1976;294:1316–21.
  • Topic A, Jelic Ivanovic Z, Spasojevic Kalimanovska V, Spasic S, Stankovic I. Distribution of alpha-1-antitrypsin phenotypes in Serbian newborns and children with liver disease. Acta Paediatrica. 2002;91:726–7.
  • Cottrall K, Cook PJL, Mowat AP. Neonatal hepatitis syndrome and alpha-1-antitrypsin deficiency: an epidemiological study in South-East England. Postgrad Med J. 1974;50:376–80.
  • Deutsch J, Smith AL, Danks DM, Campbell PE. Long term prognosis for babies with neonatal liver disease. Arch Dis Child. 1985;60:447–51.
  • Mowat AP, Psacharopoulos HT, Williams R. Extrahepatic biliary atresia versus neonatal hepatitis. Review of 137 prospectively investigated infants. Arch Dis Child. 1976;51:763–70.
  • Odièvre M, Hadchouel M, Landrieu P, Alagille D, Eliot N. Long-term prognosis for infants with intrahepatic cholestasis and patent extrahepatic biliary tract. Arch Dis Child. 1981;56:373–6.
  • Adrian-Casavilla F, Reyes J, Tzakis A, Wright HI, Gavaler JS, Lendoire J, . Liver transplantation for neonatal hepatitis as compared to the other two leading indications for liver transplantation in children. J Hepatol. 1994;21:1035–9.
  • Esquivel CO, Iwatsuki S, Gordon RD, Marsh WW Jr, Koneru B, Makowka L, . Indications for pediatric liver transplantation. J Pediatr. 1987;111:1039–45.
  • Kok KF, Wahab PJ, Houwen RH, Drenth JP, De Man RA, Van Hoek B, . Heterozygous alpha-1 antitrypsin deficiency as a co-factor in the development of chronic liver disease: a review. Neth J Med. 2007;65:160–6.
  • Elzouki AN, Eriksson S. Risk of hepatobiliary disease in adults with severe alpha 1-antitrypsin deficiency (PiZZ): is chronic viral hepatitis B or C an additional risk factor for cirrhosis and hepatocellular carcinoma?. Eur J Gastroenterol Hepatol. 1996;8:989–94.
  • Hashemi M, Alavian SM, Ghavami S, De Serres FJ, Salehi M, Doroudi T, . High prevalence of alpha 1 antitrypsin phenotypes in viral hepatitis B infected patients in Iran. Hepatol Res. 2005;33:292–7.
  • Eigenbrodt ML, McCashland TM, Dy RM, Clark J, Galati J. Heterozygous alpha 1-antitrypsin phenotypes in patients with end stage liver disease. Am J Gastroenterol. 1997;92:602–7.
  • Fischer HP, Ortiz-Pallardo ME, Ko Y, Esch C, Zhou H. Chronic liver disease in heterozygous alpha1-antitrypsin deficiency PiZ. J Hepatol. 2000;33:883–92.
  • Graziadei IW, Joseph JJ, Wiesner RH, Therneau TM, Batts KP, Porayko MK. Increased risk of chronic liver failure in adults with heterozygous alpha1-antitrypsin deficiency. Hepatology. 1998;28:1058–63.
  • Serfaty L, Chazouilleres O, Poujol-Robert A, Morand-Joubert L, Dubois C, Chretien Y, . Risk factors for cirrhosis in patients with chronic hepatitis C virus infection: results of a case-control study. Hepatology. 1997;26:776–9.
  • Vecchio FM, Fabiano A, Orsini G, Ragusa D, Massi G. Alpha-1-antitrypsin MZ phenotype and cryptogenic chronic liver disease in adults. Digestion. 1983;27:100–4.
  • Regev A, Guaqueta C, Molina EG, Conrad A, Mishra V, Brantly ML, . Does the heterozygous state of alpha-1 antitrypsin deficiency have a role in chronic liver diseases? Interim results of a large case-control study. J Pediatr Gastroenterol Nutr. 2006;43:30–5.
  • Scott BB, Egner W. Does alpha1-antitrypsin phenotype PiMZ increase the risk of fibrosis in liver disease due to hepatitis C virus infection? Eur J Gastroenterol Hepatol. 2006;18:521–3.
  • Bassett ML, Bradbear RA, Kerlin P, Clark P. α1-Antitrypsin phenotypes in chronic active hepatitis. J Gastroenterol Hepatol. 1986;1:207–11.
  • Rakela J, Goldschmiedt M, Ludwig J. Late manifestation of chronic liver disease in adults with alpha-1-antitrypsin deficiency. Dig Dis Sci. 1987;32:1358–62.
  • Vogel W, Propst T, Propst A, Dietze O, Judmaier G, Braunsteiner H. Causes of liver disease in an adult population with heterozygous and homozygous alpha 1-antitrypsin deficiency. Acta Paediatr Suppl. 1994;393:24–6.
  • Bowlus CL, Willner I, Zern MA, Reuben A, Chen P, Holladay B, . Factors associated with advanced liver disease in adults with alpha1-antitrypsin deficiency. Clin Gastroenterol Hepatol. 2005;3:390–96.

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