Autoradiography screening of potential positron emission tomography tracers for asymptomatic abdominal aortic aneurysms

References

• Tamarina NA, McMillan WD, Shively VP, Pearce WH. Expression of matrix metalloproteinases and their inhibitors in aneurysms and normal aorta. Surgery. 1997;122:264–71.
   PubMed Web of Science ®Google Scholar
• Kadoglou NP, Liapis CD. Matrix metalloproteinases: contribution to pathogenesis, diagnosis, surveillance and treatment of abdominal aortic aneurysms. Curr Med Res Opin. 2004;20:419–32.
   PubMed Web of Science ®Google Scholar
• Jacob T, Ascher E, Hingorani A, Gunduz Y, Kallakuri S. Initial steps in the unifying theory of the pathogenesis of artery aneurysms. J Surg Res. 2001;101:37–43.
   Google Scholar
• Choke E, Thompson MM, Dawson J, Wilson WR, Sayed S, Loftus IM, et al. Abdominal aortic aneurysm rupture is associated with increased medial neovascularization and overexpression of proangiogenic cytokines. Arterioscler Thromb Vasc Biol. 2006;26:2077–82.
   PubMed Web of Science ®Google Scholar
• Lin S-A, Patel M, Suresch D, Connolly B, Bao B, Groves K, et al. Quantitative longitudinal imaging of vascular inflammation and treatment by ezetimibe in apoE mice by FMT using new optical imaging biomarkers of cathepsin activity and integrin. Int J Mol Imaging. 2012;2012:189254.
   Google Scholar
• Blom E. Development of 18F- and 68Ga-labelled tracers: design perspectives and the search for faster synthesis. University of Uppsala, Sweden: Acta Universitatis Upsaliensis; 2009.
   Google Scholar
• Christopeit T, Gossas T, Danielson UH. Characterization of Ca2+ and phosphocholine interactions with C-reactive protein using a surface plasmon resonance biosensor. Anal Biochem. 2009;391:39–44.
   PubMed Web of Science ®Google Scholar
• Black S, Kushner I, Samols D. C-reactive protein. J Biol Chem. 2004;279:48487–90.
   PubMed Web of Science ®Google Scholar
• Zavala F, Haumont J, Lenfant M. Interaction of benzodiazepines with mouse macrophages. Eur J Pharmacol. 1984;106:561–6.
   PubMed Web of Science ®Google Scholar
• Vowinckel E, Reutens D, Becher B, Verge G, Evans A, Owens T, et al. PK11195 binding to the peripheral benzodiazepine receptor as a marker of microglia activation in multiple sclerosis and experimental autoimmune encephalomyelitis. J Neurosci Res. 1997;50:345–53.
   PubMed Web of Science ®Google Scholar
• Pappata S, Levasseur M, Gunn RN, Myers R, Crouzel C, Syrota A, et al. Thalamic microglial activation in ischemic stroke detected in vivo by PET and [11C]PK1195. Neurology. 2000;55:1052–4.
   PubMed Web of Science ®Google Scholar
• Banati RB, Newcombe J, Gunn RN, Cagnin A, Turkheimer F, Heppner F, et al. The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity. Brain. 2000;123:2321–37.
   PubMed Web of Science ®Google Scholar
• Cagnin A, Brooks DJ, Kennedy AM, Gunn RN, Myers R, Turkheimer FE, et al. In-vivo measurement of activated microglia in dementia. Lancet. 2001;358:461–7.
   PubMed Web of Science ®Google Scholar
• Goerres GW, Revesz T, Duncan J, Banati RB. Imaging cerebral vasculitis in refractory epilepsy using [11C](R)-PK11195 positron emission tomography. AJR Am J Roentgenol. 2001;176:1016–18.
   Google Scholar
• Maeda J, Suhara T, Zhang MR, Okauchi T, Yasuno F, Ikoma Y, et al. Novel peripheral benzodiazepine receptor ligand [11C]DAA1106 for PET: an imaging tool for glial cells in the brain. Synapse. 2004;52:283–91.
   PubMed Web of Science ®Google Scholar
• Pugliese F, Gaemperli O, Kinderlerer AR, Lamare F, Shalhoub J, Davies AH, et al. Imaging of vascular inflammation with [11C]-PK11195 and positron emission tomography/computed tomography angiography. J Am Coll Cardiol. 2010;56:653–61.
   PubMed Web of Science ®Google Scholar
• Owen DRJ, Gunn RN, Rabiner EA, Bennacef I, Fujita M, Kreisl WC, et al. Mixed-affinity binding in humans with 18-kDa translocator protein ligands. J Nucl Med. 2011;52:24–32.
   PubMed Web of Science ®Google Scholar
• Danfors T, Bergström M, Feltelius N, Ahlström H, Westerberg G, Långström B. Positron emission tomography with 11C-D-Deprenyl in patients with rheumatoid arthritis. Evaluation of knee joint inflammation before and after intra-articular glucocorticoid treatment. Scand J Rheumatol. 1997;26:43–8.
   PubMed Web of Science ®Google Scholar
• Linnman C, Appel L, Fredrikson M, Gordh T, Söderlund A, Långström B, et al. Elevated [11C]-D-deprenyl uptake in chronic whiplash associated disorder suggests persistent musculoskeletal inflammation. PLoS One. 2011;6:e19182.
   Google Scholar
• Glaser M, Morrison M, Solbakken M, Arukwe J, Karlsen H, Wiggen U, et al. Radiosynthesis and biodistribution of cyclic RGD peptides conjugated with novel [18F]fluorinated aldehyde-containing prosthetic groups. Bioconjug Chem. 2008;19:951–7.
   PubMed Web of Science ®Google Scholar
• Kenny LM, Coombes RC, Oulie I, Contractor KB, Miller M, Spinks TJ, et al. Phase I trial of the positron-emitting Arg-Gly-Asp (RGD) peptide radioligand 18F-AH111585 in breast cancer patients. J Nucl Med. 2008;49:879–86.
   PubMed Web of Science ®Google Scholar
• Morrison MS, Ricketts SA, Barnett J, Cuthbertson A, Tessier J, Wedge SR. Use of a novel Arg-Gly-Asp Radioligand, 18F-AH111585, to determine changes in tumor vascularity after antitumor therapy. J Nucl Med. 2009;50:116–22.
   Google Scholar
• Brooks PC, Clark RA, Cheresh DA. Requirement of vascular integrin αVβ3 for angiogenesis. Science. 1994;264:569–71.
   PubMed Web of Science ®Google Scholar
• Bishop GG, McPherson JA, Sanders JM, Hesselbacher SE, Feldman MJ, McNamara CA, et al. Selective αvβ3-receptor blockade reduces macrophage infiltration and restenosis after balloon angioplasty in the atherosclerotic rabbit. Circulation. 2001;103:1906–11.
   PubMed Web of Science ®Google Scholar
• Gordon S. Alternative activation of macrophages. Nat Rev Immunol. 2003;3:23–35.
   PubMed Web of Science ®Google Scholar
• Antonov AS, Kolodgie FD, Munn DH, Gerrity RG. Regulation of macrophage foam cell formation by αVβ3 integrin: potential role in human atherosclerosis. Am J Pathol. 2004;165:247–58.
   PubMed Web of Science ®Google Scholar
• Coller BS, Cheresh DA, Asch E, Seligsohn U. Platelet vitronectin receptor expression differentiates Iraqi-Jewish from arab patients with Glanzmann thrombasthenia in Israel. Blood. 1991;77:75–83.
   PubMed Web of Science ®Google Scholar
• Zheleznyak A, Wadas T, Sherman C, Wilson J, Kostenuik P, Weilbaecher K, et al. Integrin αvβ3 as a PET imaging biomarker for osteoclast number in mouse models of negative and positive osteoclast regulation. Mol Imaging Biol. 2012;14:500–8.
   Google Scholar
• Horton MA. The αvβ3 integrin vitronectin receptor. Int J Biochem Cell Biol. 1997;29:721–5.
   PubMed Web of Science ®Google Scholar
• Conforti G, Dominguez-Jimenez C, Zanetti A, Gimbrone MA Jr, Cremona O, Marchisio PC, et al. Human endothelial cells express integrin receptors on the luminal aspect of their membrane. Blood. 1992;80:437–46.
   PubMed Web of Science ®Google Scholar
• Montgomery AM, Reisfeld RA, Cheresh DA. Integrin αvβ3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proc Natl Acad Sci USA. 1994;91:8856–60.
   PubMed Web of Science ®Google Scholar
• Fowler JS, Logan J, Volkow ND, Wang GJ. Translational neuroimaging: positron emission tomography studies of monoamine oxidase. Mol Imaging Biol. 2005;7:377–87.
   Google Scholar
• Fowler JS, MacGregor RR, Wolf AP, Arnett CD, Dewey SL, Schlyer D, et al. Mapping human brain monoamine oxidase A and B with 11C-labeled suicide inactivators and PET. Science. 1987;235:481–5.
   PubMed Web of Science ®Google Scholar
• MacGregor RR, Fowler JS, Wolf AP, Halldin C, Långström B. Synthesis of suicide inhibitors of monoamine oxidase: carbon-11 labeled clorgyline, L-deprenyl and D-deprenyl. J Labelled Comp Radiopharm. 1988;25:1–9.
   Google Scholar
• Fowler JS, Wang GJ, Logan J, Xie S, Volkow ND, MacGregor RR, et al. Selective reduction of radiotracer trapping by deuterium substitution: comparison of carbon-11-L-Deprenyl and carbon-11-Deprenyl-D2 for MAO B mapping. J Nucl Med. 1995;36:1255–62.
   Google Scholar
• Kumlien E, Bergström M, Lilja A, Andersson J, Szekeres V, Westerberg CE, et al. Positron emission tomography with 11C-deuterium-deprenyl in temporal lobe epilepsy. Epilepsia. 1995;36:712–21.
   PubMed Web of Science ®Google Scholar
• Kumlien E, Nilsson A, Hagberg G, Långström B, Bergström M. PET with 11C-deuterium-deprenyl and 18F-FDG in focal epilepsy. Acta Neurol Scand. 2001;103:360–6.
   PubMed Web of Science ®Google Scholar
• Carter SF, Schöll M, Almkvist O, Wall A, Engler H, Långström B, et al. Evidence for astrocytosis in prodromal alzheimer disease provided by 11C-Deuterium-L-Deprenyl: a multitracer PET paradigm combining 11C-Pittsburgh compound B and 18F-FDG. J Nucl Med. 2012;53:37–46.
   Google Scholar
• Klunk WE, Engler H, Nordberg A, Wang Y, Blomqvist G, Holt DP, et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh compound-B. Ann Neurol. 2004;55:306–19.
   PubMed Web of Science ®Google Scholar
• Hall H, Velikyan I, Blom E, Ulin J, Monazzam A, Påhlman L, et al. In vitro autoradiography of carcinoembryonic antigen in tissue from patients with colorectal cancer using multifunctional antibody TF2 and 67/68Ga-labeled haptens by pretargeting. Am J Nucl Med Mol Imaging. 2012;2:141–50.
   PubMedGoogle Scholar
• Bergström M, Bonasera TA, Lu L, Bergström E, Backlin C, Juhlin C, et al. In vitro and in vivo primate evaluation of carbon-11-etomidate and carbon-11-metomidate as potential tracers for PET imaging of the adrenal cortex and its tumors. J Nucl Med. 1998;39:982–9.
   PubMed Web of Science ®Google Scholar
• Erlandsson M, Karimi F, Lindhe Ö, Långström B. 18F-Labelled metomidate analogues as adrenocortical imaging agents. Nucl Med Biol. 2009;36:435–45.
   Google Scholar
• Ettlinger DE, Wadsak W, Mien LK, Machek M, Wabnegger L, Rendl G, et al. [18F]FETO: metabolic considerations. Eur J Nucl Med Mol Imaging. 2006;33:928–31.
   Google Scholar
• Wouters W, Van Ginckel R, Krekels M, Bowden C, De Coster R. Pharmacology of vorozole. J Steroid Biochem Mol Biol. 1993;44:617–21.
   Google Scholar
• Erlandsson M, Karimi F, Takahashi K, Långström B. 18F-Labelled vorozole analogues as PET tracer for aromatase. J Labelled Comp Radiopharm. 2008;51:207–12.
   Google Scholar
• Hall H, Takahashi K, Erlandsson M, Estrada S, Razifar P, Bergström E, et al. Pharmacological characterization of 18F-labeled vorozole analogs. J Labelled Comp Radiopharm. 2012;55:484–90.
   Google Scholar
• Takahashi K, Bergström M, Frändberg P, Vesström EL, Watanabe Y, Långström B. Imaging of aromatase distribution in rat and rhesus monkey brains with [11C]vorozole. Nucl Med Biol. 2006;33:599–605.
   Google Scholar
• Lidström P, Bonasera TA, Kirilovas D, Lindblom B, Lu L, Bergström E, et al. Synthesis, in vivo rhesus monkey biodistribution and in vitro evaluation of a 11C-labelled potent aromatase inhibitor: [N-methyl-11C]vorozole. Nucl Med Biol. 1998;25:497–501.
   Google Scholar
• Bengtsson H, Bergqvist D. Ruptured abdominal aortic aneurysm: a population-based study. J Vasc Surg. 1993;18:74–80.
   PubMed Web of Science ®Google Scholar
• Tegler G, Ericson K, Sörensen J, Björck M, Wanhainen A. Inflammation in the walls of asymptomatic abdominal aortic aneurysms is not associated with increased metabolic activity detectable by 18-fluorodeoxglucose positron-emission tomography. J Vasc Surg. 2012;56:802–7.
   Google Scholar
• Palombo D, Morbelli S, Spinella G, Pane B, Marini C, Rousas N, et al. A positron emission tomography/computed tomography (PET/CT) evaluation of asymptomatic abdominal aortic aneurysms: another point of view. Ann Vasc Surg. 2012;26:491–9.
   Google Scholar
• Tegler G, Sörensen J, Ericson K, Björck M, Wanhainen A. 4D-PET/CT with [11C]-PK11195 and [11C]-D-deprenyl does not identify the chronic inflammation in asymptomatic abdominal aortic aneurysms. Eur J Vasc Endovasc Surg. 2013;45:351–6.
   Google Scholar
• Hatanaka K, Li X-A, Masuda K, Yutani C, Yamamoto A. Immunohistochemical localization of C-reactive protein-binding sites in human atherosclerotic aortic lesions by a modified streptavidin-biotin-staining method. Pathol Int. 1995;45:635–41.
   PubMed Web of Science ®Google Scholar
• Benjamin HB, Bartenbach G, Zeit W. The importance of the vasa vasorum of the aorta. Surg Gynecol Obstet. 1960;110:224–8.
   Google Scholar
• Paik DC, Fu C, Bhattacharya J, Tilson MD. Ongoing angiogenesis in blood vessels of the abdominal aortic aneurysm. Exp Mol Med. 2004;36:524–33.
   Google Scholar