Enlarged right-sided dimensions and fibrosis of the right ventricular insertion point on cardiovascular magnetic resonance imaging is seen early in patients with pulmonary arterial hypertension associated with connective tissue disease

References

• LeRoy EC, Black C, Fleischmajer R, Jablonska S, Krieg T, Medsger TA Jr, Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol 1988;15:202–5.
   PubMed Web of Science ®Google Scholar
• Bryan C, Howard Y, Brennan P, Black C, Silman A. Survival following the onset of scleroderma: results from a retrospective inception cohort study of the UK patient population. Br J Rheumatol 1996;35:1122–6.
   PubMedGoogle Scholar
• Hesselstrand R, Scheja A, Akesson A. Mortality and causes of death in a Swedish series of systemic sclerosis patients. Ann Rheum Dis 1998;57:682–6.
   PubMed Web of Science ®Google Scholar
• Lee P, Langevitz P, Alderdice CA, Aubrey M, Baer PA, Baron M, Mortality in systemic sclerosis (scleroderma). Q J Med 1992;82:139–48.
   PubMedGoogle Scholar
• Simeón CP, Armadans L, Fonollosa V, Solans R, Selva A, Villar M, Mortality and prognostic factors in Spanish patients with systemic sclerosis. Rheumatology (Oxford) 2003;42:71–5.
   PubMed Web of Science ®Google Scholar
• Steen VD, Medsger TA. Changes in causes of death in systemic sclerosis, 1972–2002. Ann Rheum Dis 2007;66:940–4.
   PubMed Web of Science ®Google Scholar
• Ferri C, Emdin M, Nielson H, Bruhlmann P. Assessment of heart involvement. Clin Exp Rheumatol 2003;21(Suppl 29):S24–8.
   PubMedGoogle Scholar
• Plastiras SC, Kelekis N, Tzelepis GE. Magnetic resonance imaging for the detection of myocardial fibrosis in scleroderma. N Engl J Med 2006;354:2194–6.
   PubMedGoogle Scholar
• Tzelepis GE, Kelekis NL, Plastiras SC, Mitseas P, Economopoulos N, Kampolis C, Pattern and distribution of myocardial fibrosis in systemic sclerosis. A delayed enhanced magnetic resonance imaging study. Arthritis Rheum 2007;56:3827–36.
   PubMed Web of Science ®Google Scholar
• Bezante GP, Rollando D, Sessarego M, Panico N, Setti M, Filaci G, Cardiac magnetic resonance imaging detects subclinical right ventricular impairment in systemic sclerosis. J Rheumatol 2007;34:2431–7.
   PubMedGoogle Scholar
• Nassenstein K, Breuckmann F, Huger M, Ladd SC, Schlosser T, Kreuter A, Detection of myocardial fibrosis in systemic sclerosis by contrast-enhanced magnetic resonance imaging. Rofo 2008;180:1054–60.
   PubMedGoogle Scholar
• Hachulla AL, Launay D, Gaxotte V, de Groote P, Lamblin N, Devos P, Cardiac magnetic resonance imaging in systemic sclerosis: a cross-sectional observational study of 52 patients. Ann Rheum Dis 2009;68:1878–84.
   PubMed Web of Science ®Google Scholar
• Kobayashi H, Yokoe I, Hirano M, Nakamura T, Nakajima Y, Fontaine KR, Cardiac magnetic resonance imaging with pharmacological stress perfusion and delayed enhancement in asymptomatic patients with systemic sclerosis. J Rheumatol 2009;36:106–12.
   PubMed Web of Science ®Google Scholar
• Allanore Y, Meune C, Vignaux O, Weber S, Legmann P, Kahan A. Bosentan increases myocardial perfusion and function in systemic sclerosis: a magnetic resonance imaging and Tissue-Doppler echography study. J Rheumatol 2006;33:2464–9.
   PubMed Web of Science ®Google Scholar
• Hsu VM, Moreyra AE, Wilson AC, Shinnar M, Shindler DM, Wilson JE, Assessment of pulmonary arterial hypertension in patients with systemic sclerosis: comparison of noninvasive tests with results of right-heart catheterization. J Rheumatol 2008;35:458–65.
   PubMed Web of Science ®Google Scholar
• Simonneau G, Galiè N, Rubin LJ, Langleben D, Seeger W, Domenighetti G, Clinical classification of pulmonary hypertension. J Am Coll Cardiol 2004;43(Suppl S):5S–12S.
   PubMedGoogle Scholar
• Masi AT, Medsger TA Jr, Altman RD, D'Angelo WA, Fries JF, LeRoy EC, Preliminary criteria for the classification of systemic sclerosis (scleroderma). Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. Arthritis Rheum 1980;23:581–90.
   PubMed Web of Science ®Google Scholar
• LeRoy EC, Medsger TA Jr. Criteria for the classification of early systemic sclerosis. J Rheumatol 2001;28:1573–6.
   PubMed Web of Science ®Google Scholar
• Pennell DJ. Ventricular volume and mass by CMR. J Cardiovasc Magn Reson 2002;4:507–13.
   PubMed Web of Science ®Google Scholar
• Maceira AM, Prasad SK, Khan M, Pennell DJ. Normalized left ventricular systolic and diastolic function by steady state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson 2006;8:417–26.
   PubMed Web of Science ®Google Scholar
• Arheden H, Saeed M, Higgins CB, Gao DW, Bremerich J, Wyttenbach R, Measurement of the distribution volume of gadopentetate dimeglumine at echo-planar MR imaging to quantify myocardial infarction: comparison with 99mTc-DTPA autoradiography in rats. Radiology 1999;211:698–708.
   PubMed Web of Science ®Google Scholar
• Abdel-Aty H, Zagrosek A, Schulz-Menger J, Taylor AJ, Messroghli D, Kumar A, Delayed enhancement and T2-weighted cardiovascular magnetic resonance imaging differentiate acute from chronic myocardial infarction. Circulation 2004;109:2422–6.
   Google Scholar
• Simonetti OP, Kim RJ, Fieno DS, Hillenbrand HB, Wu E, Bundy JM, An improved MR imaging technique for the visualization of myocardial infarction. Radiology 2001;218:215–23.
   PubMed Web of Science ®Google Scholar
• Maceira AM, Prasad SK, Khan M, Pennell DJ. Reference right ventricular systolic and diastolic function normalized to age, gender and body surface area from steady-state free precession cardiovascular magnetic resonance. Eur Heart J 2006;23:2879–88.
   Google Scholar
• Maceira AM, Prasad SK, Khan M, Pennell DJ. Normalized left ventricular systolic and diastolic function by steady state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson 2006;3:417–26.
   Google Scholar
• McCann GP, Gan CT, Beek AM, Niessen HW, Vonk Noordegraaf A, van Rossum AC. Extent of MRI delayed enhancement of myocardial mass is related to right ventricular dysfunction in pulmonary artery hypertension. AJR Am J Roentgenol 2007;188:349–55.
   PubMed Web of Science ®Google Scholar
• Blyth KG, Groenning BA, Martin TN, Foster JE, Mark PB, Dargie HJ, Contrast enhanced-cardiovascular magnetic resonance imaging in patients with pulmonary hypertension. Eur Heart J 2005;26:1993–9.
   PubMed Web of Science ®Google Scholar