Ultraviolet radiation-induced cytokines promote mast cell accumulation and matrix metalloproteinase production: potential role in cutaneous lupus erythematosus

References

• Werth VP. Clinical manifestations of cutaneous lupus erythematosus. Autoimmun Rev 2005;4:296–302.
   PubMed Web of Science ®Google Scholar
• Crowson AN, Magro C. The cutaneous pathology of lupus erythematosus: a review. J Cutaneous Pathol 2001;28:1–23.
   PubMed Web of Science ®Google Scholar
• Kuhn A, Krammer PH, Kolb-Bachofen V. Pathophysiology of cutaneous lupus erythematosus – novel aspects. Rheumatology (Oxford) 2006;45(Suppl 3):iii14–16.
   PubMedGoogle Scholar
• Kuhn A, Sonntag M, Richter-Hintz D, Oslislo C, Megahed M, Ruzicka T, Phototesting in lupus erythematosus: a 15-year experience. J Am Acad Dermatol 2001;45:86–95.
   PubMed Web of Science ®Google Scholar
• Meller S, Winterberg F, Gilliet M, Muller A, Lauceviciute I, Rieker J, Ultraviolet radiation-induced injury, chemokines, and leukocyte recruitment: an amplification cycle triggering cutaneous lupus erythematosus. Arthritis Rheum 2005;52:1504–16.
   PubMed Web of Science ®Google Scholar
• Janssens AS, Lashley EE, Out-Luiting CJ, Willemze R, Pavel S, de Gruijl FR. UVB-induced leucocyte trafficking in the epidermis of photosensitive lupus erythematosus patients: normal depletion of Langerhans cells. Exp Dermatol 2005;14:138–42.
   PubMed Web of Science ®Google Scholar
• Robson MG, Walport MJ. Pathogenesis of systemic lupus erythematosus (SLE). Clin Exp Allergy 2001;31:678–85.
   PubMed Web of Science ®Google Scholar
• Kuechle MK, Elkon KB. Shining light on lupus and UV. Arthritis Res Ther 2007;9:101.
   PubMed Web of Science ®Google Scholar
• Kanbe N, Tanaka A, Kanbe M, Itakura A, Kurosawa M, Matsuda H. Human mast cells produce matrix metalloproteinase 9. Eur J Immunol 1999;29:2645–9.
   PubMed Web of Science ®Google Scholar
• Di Girolamo N, Indoh I, Jackson N, Wakefield D, McNeil HP, Yan W, Human mast cell-derived gelatinase B (matrix metalloproteinase-9) is regulated by inflammatory cytokines: role in cell migration. J Immunol 2006;177:2638–50.
   PubMed Web of Science ®Google Scholar
• Norrby K. Mast cells and angiogenesis. APMIS 2002;110:355–71.
   PubMed Web of Science ®Google Scholar
• Tanaka A, Arai K, Kitamura Y, Matsuda H. Matrix metalloproteinase-9 production, a newly identified function of mast cell progenitors, is downregulated by c-kit receptor activation. Blood 1999;94:2390–5.
   PubMed Web of Science ®Google Scholar
• Ram M, Sherer Y, Shoenfeld Y. Matrix metalloproteinase-9 and autoimmune diseases. J Clin Immunol 2006;26:299–307.
   PubMed Web of Science ®Google Scholar
• Jackson NE, Wang HW, Tedla N, McNeil HP, Geczy CL, Collins A, IL-15 induces mast cell migration via a pertussis toxin-sensitive receptor. Eur J Immunol 2005;35:2376–85.
   PubMed Web of Science ®Google Scholar
• Mattoli S, Ackerman V, Vittori E, Marini M. Mast cell chemotactic activity of RANTES. Biochem Biophys Res Commun 1995;209:316–21.
   PubMed Web of Science ®Google Scholar
• Kuhn A, Ruzicka T. Classification of cutaneous lupus erythematosus. In: Kuhn A, Lehmann P, Ruzicka T, editors. Cutaneous lupus erythematosus. Heidelberg: Springer, 2004:53–9.
   Google Scholar
• Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1997;40:1725.
   PubMed Web of Science ®Google Scholar
• Mawrin C, Brunn A, Rocken C, Schroder JM. Peripheral neuropathy in systemic lupus erythematosus: pathomorphological features and distribution pattern of matrix metalloproteinases. Acta Neuropathol (Berl) 2003;105:365–72.
   PubMed Web of Science ®Google Scholar
• Macluskey M, Chandrachud LM, Pazouki S, Green M, Chisholm DM, Ogden GR, Apoptosis, proliferation, and angiogenesis in oral tissues. Possible relevance to tumour progression. J Pathol 2000;191:368–75.
   PubMed Web of Science ®Google Scholar
• Onoue S, Kobayashi T, Takemoto Y, Sasaki I, Shinkai H. Induction of matrix metalloproteinase-9 secretion from human keratinocytes in culture by ultraviolet B irradiation. J Dermatol Sci 2003; 33:105–11.
   PubMed Web of Science ®Google Scholar
• Yano S, Komine M, Fujimoto M, Okochi H, Tamaki K. Interleukin 15 induces the signals of epidermal proliferation through ERK and PI 3-kinase in a human epidermal keratinocyte cell line, HaCaT. Biochem Biophys Res Commun 2003;301:841–7.
   PubMed Web of Science ®Google Scholar
• Mohamadzadeh M, Takashima A, Dougherty I, Knop J, Bergstresser PR, Cruz PD Jr. Ultraviolet B radiation up-regulates the expression of IL-15 in human skin. J Immunol 1995;155:4492–6.
   PubMed Web of Science ®Google Scholar
• Benoist C, Mathis D. Mast cells in autoimmune disease. Nature 2002;420:875–8.
   PubMed Web of Science ®Google Scholar
• Fairhurst AM, Wandstrat AE, Wakeland EK. Systemic lupus erythematosus: multiple immunological phenotypes in a complex genetic disease. Adv Immunol 2006;92:1–69.
   PubMed Web of Science ®Google Scholar
• Sayed BA, Brown MA. Mast cells as modulators of T-cell responses. Immunol Rev 2007;217:53–64.
   PubMed Web of Science ®Google Scholar
• Lukacs NW, Hogaboam CM, Kunkel SL, Chensue SW, Burdick MD, Evanoff HL, Mast cells produce ENA-78, which can function as a potent neutrophil chemoattractant during allergic airway inflammation. J Leukoc Biol 1998;63:746–51.
   PubMed Web of Science ®Google Scholar
• Shakoory B, Fitzgerald SM, Lee SA, Chi DS, Krishnaswamy G. The role of human mast cell-derived cytokines in eosinophil biology. J Interferon Cytokine Res 2004;24:271–81.
   PubMed Web of Science ®Google Scholar
• Gordon JR. TGFbeta1 and TNFalpha secreted by mast cells stimulated via the FcepsilonRI activate fibroblasts for high-level production of monocyte chemoattractant protein-1 (MCP-1). Cell Immunol 2000;201:42–9.
   PubMed Web of Science ®Google Scholar
• Meyer MC, Creer MH, McHowat J. Potential role for mast cell tryptase in recruitment of inflammatory cells to endothelium. Am J Physiol 2005;289:C1485–91.
   PubMed Web of Science ®Google Scholar
• Yamamoto T, Katayama I, Nishioka K. Mast cell numbers in multiple dermatofibromas. Dermatology 1995;190:9–13.
   PubMed Web of Science ®Google Scholar
• Fagot D, Asselineau D, Bernerd F. Direct role of human dermal fibroblasts and indirect participation of epidermal keratinocytes in MMP-1 production after UV-B irradiation. Arch Dermatol Res 2002;293:576–83.
   PubMed Web of Science ®Google Scholar
• Baba H, Uchiwa H, Watanabe S. UVB irradiation increases the release of SCF from human epidermal cells. J Invest Dermatol 2005;124:1075–7.
   PubMed Web of Science ®Google Scholar
• Kock A, Schwarz T, Kirnbauer R, Urbanski A, Perry P, Ansel JC, Human keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light. J Exp Med 1990;172:1609–14.
   PubMed Web of Science ®Google Scholar
• Heissig B, Hattori K, Dias S, Friedrich M, Ferris B, Hackett NR, Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell 2002;109:625–37.
   PubMed Web of Science ®Google Scholar
• Visse R, Nagase H. Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ Res 2003;92:827–39.
   PubMed Web of Science ®Google Scholar
• Deshmukh US, Gaskin F, Lewis JE, Kannapell CC, Fu SM. Mechanisms of autoantibody diversification to SLE-related autoantigens. Ann N Y Acad Sci 2003;987:91–8.
   PubMed Web of Science ®Google Scholar
• Graham KL, Utz PJ. Sources of autoantigens in systemic lupus erythematosus. Curr Opin Rheumatol 2005;17:513–17.
   PubMed Web of Science ®Google Scholar
• Schwarz T. Mechanisms of UV-induced immunosuppression. Keio J Med 2005;54:165–71.
   PubMedGoogle Scholar
• Kuhn A, Herrmann M, Kleber S, Beckmann-Welle M, Fehsel K, Martin-Villalba A, Accumulation of apoptotic cells in the epidermis of patients with cutaneous lupus erythematosus after ultraviolet irradiation. Arthritis Rheum 2006;54:939–50.
   PubMed Web of Science ®Google Scholar
• Reefman E, Kuiper H, Jonkman MF, Limburg PC, Kallenberg CG, Bijl M. Skin sensitivity to UVB irradiation in systemic lupus erythematosus is not related to the level of apoptosis induction in keratinocytes. Rheumatology (Oxford) 2006; 45:538–44.
   PubMed Web of Science ®Google Scholar
• Reefman E, de Jong MC, Kuiper H, Jonkman MF, Limburg PC, Kallenberg CG, Is disturbed clearance of apoptotic keratinocytes responsible for UVB-induced inflammatory skin lesions in systemic lupus erythematosus? Arthritis Res Ther 2006; 8:R156.
   Web of Science ®Google Scholar
• Muller DM, Pender MP, Greer JM. Chemokines and chemokine receptors: potential therapeutic targets in multiple sclerosis. Curr Drug Targets Inflamm Allergy 2004;3:279–90.
   PubMedGoogle Scholar
• Rottem M, Mekori YA. Mast cells and autoimmunity. Autoimmun Rev 2005;4:21–7.
   PubMed Web of Science ®Google Scholar
• Eklund KK. Mast cells in the pathogenesis of rheumatic diseases and as potential targets for anti-rheumatic therapy. Immunol Rev 2007;217:38–52.
   PubMed Web of Science ®Google Scholar
• Mortier E, Bernard J, Plet A, Jacques Y. Natural, proteolytic release of a soluble form of human IL-15 receptor alpha-chain that behaves as a specific, high affinity IL-15 antagonist. J Immunol 2004;173:1681–8.
   PubMed Web of Science ®Google Scholar
• Baslund B, Tvede N, Danneskiold-Samsoe B, Larsson P, Panayi G, Petersen J, Targeting interleukin-15 in patients with rheumatoid arthritis: a proof-of-concept study. Arthritis Rheum 2005;52:2686–92.
   PubMed Web of Science ®Google Scholar
• Cawston TE. Metalloproteinase inhibitors and the prevention of connective tissue breakdown. Pharmacol Ther 1996;70:163–82.
   PubMed Web of Science ®Google Scholar
• Mengshol JA, Mix KS, Brinckerhoff CE. Matrix metalloproteinases as therapeutic targets in arthritic diseases: bull's-eye or missing the mark? Arthritis Rheum 2002;46:13–20.
   PubMed Web of Science ®Google Scholar
• Close DR. Matrix metalloproteinase inhibitors in rheumatic diseases. Ann Rheum Dis 2001;60(Suppl 3):iii62–7.
   PubMed Web of Science ®Google Scholar
• Catterall JB, Cawston TE. Drugs in development: bisphosphonates and metalloproteinase inhibitors. Arthritis Res Ther 2003; 5:12–24.
   PubMed Web of Science ®Google Scholar