Expression of RXFP1 in skin of scleroderma patients and control subjects

References

• Bathgate RA, Samuel CS, Burazin TC, Gundlach AL, Tregear GW. Relaxin: new peptides receptors and novel actions. Trends Endocrinol Metab 2003;14:207–13.
   PubMed Web of Science ®Google Scholar
• Hsu SY, Nakabayashi K, Nishi S, Kumagai J, Kudo M, Sherwood OD, . Activation of orphan receptor by the hormone relaxin. Science 2002;295:671–4.
   PubMed Web of Science ®Google Scholar
• Samuel CS, Unemori EN, Mookerjee I, Bathgate RA, Layfield SL, Mak J, . Relaxin modulates cardiac fibroblast proliferation differentiation and collagen production and reverses cardiac fibrosis in vivo. Endocrinology 2004;145:4125–33.
   PubMed Web of Science ®Google Scholar
• Unemori EN, Bauer EA, Amento EP. Relaxin alone and in conjunction with interferon-γ decreases collagen synthesis by cultured human scleroderma fibroblasts. J Invest Dermatol 1992;99:337–42.
   PubMedGoogle Scholar
• Seibold JR, Korn JH, Simms R, Clements PJ, Moreland LW, Mayes MD, . Recombinant human relaxin in the treatment of scleroderma: a randomized, double-blind, placebo-controlled trial. Ann Intern Med 2000;132:871–9.
   PubMed Web of Science ®Google Scholar
• Khanna D, Clements PJ, Furst DE, Park GS, Hays RD, Yoon J, . Recombinant human relaxin in the treatment of systemic sclerosis with diffuse cutaneous involvement: a randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2009;60:1102–11.
   PubMed Web of Science ®Google Scholar
• Subcommittee for Scleroderma Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee: preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum 1980;23:581–90.
   PubMed Web of Science ®Google Scholar
• Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248–54.
   PubMed Web of Science ®Google Scholar
• Cooney TE, Gor RA, Pfaff DW, Schober J. Detection of RXFP1 receptors in skin biopsies from children with congenital adrenal hyperplasia: a preliminary report. J Pediatr Urol 2010;6:389–95.
   PubMedGoogle Scholar
• Callander GE, Thomas WG, Bathgate RA. Prolonged RXFP1 and RXFP2 signaling can be explained by poor internalization and a lack of beta-arrestin recruitment Am J Physiol Cell Physiol 2009;296:C1058–66.
   Google Scholar
• Shirota K, Tateishi K, Koji T, Hishikawa Y, Hachisuga T, Kuroki M, . Early human preantral follicles have relaxin and relaxin receptor (LGR7), and relaxin promotes their development. J Clin Endocrinol Metab 2005;90:516–21.
   PubMedGoogle Scholar
• Lowndes K, Amano A, Yamamoto SY, Bryant-Greenwood GD. The human relaxin receptor (LGR7): expression in the fetal membranes and placenta. Placenta 2006;27:610–18.
   PubMed Web of Science ®Google Scholar
• Dragoo JL, Lee RS, Benhaim P, Finerman GA, Hame SL. Relaxin receptors in the human female anterior cruciate ligament. Am J Sports Med 2003;31:577–84.
   PubMed Web of Science ®Google Scholar
• Novak J, Parry LJ, Matthews JE, Kerchner LJ, Indovina K, Hanley-Yanez K,. Evidence for local relaxin ligand-receptor expression and function in arteries. FASEB J 2006;20:2353–62.
   Google Scholar
• Morelli SS, Petraglia F, Weiss G, Luisi S, Florio P, Wojtczuk A, . Endometrial expression of relaxin and relaxin receptor in endometriosis. Fertil Steril 2010;94:2885–7.
   PubMedGoogle Scholar
• Samuel CS, Unemori EN, Mookerjee I, Bathgate RA, Layfield SL, Mak J, . Relaxin modulates cardiac fibroblast proliferation differentiation and collagen production and reverses cardiac fibrosis in vivo. Endocrinology 2004;145:4125–33.
   PubMed Web of Science ®Google Scholar
• Muda M, He C, Martini PG, Ferraro T, Layfield S, Taylor D, . Splice variants of the relaxin and INSL3 receptors reveal unanticipated molecular complexity. Mol Hum Reprod 2005; 11:591–600.
   PubMedGoogle Scholar
• Kong RC, Shilling PJ, Lobb DK, Gooley PR, Bathgate RA. Membrane receptors: structure and function of the relaxin family peptide receptors. Mol Cell Endocrinol 2010;320:1–15.
   PubMed Web of Science ®Google Scholar
• Giordano N, Papakostas P, Lucani B, Amendola A, Cipolli F, Agate VM, . Serum relaxin in systemic sclerosis. J Rheumatol 2005;32:2164–6.
   PubMed Web of Science ®Google Scholar