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Original Article

B-cell Growth-promoting Activity in Supernatants from CD4+ Cells from Synovial Fluid and Peripheral Blood of Patients with Rheumatoid Arthritis and Other Inflammatory Arthritides

Pages 385-392 | Received 08 May 1989, Published online: 12 Jul 2009

References

  • Burmester G R, Yu D T, Irani A M, Kunkel H G, Winchester RJ. 1a+ T cells in synovial fluid and tissue of patients with rheumatoid arthritis. Arthritis Rheum 1981; 24: 1370–6
  • Waalen K, Førre Ø, Linker-Israeli M, Thoen J. Evidence of an activated T-cell system with augmented turnover of interleukin 2 in rheumatoid arthritis. Scand J Immunol 1987; 25: 367–73
  • Hovdenes J, Gaudernack G, Kvien T K, Egeland T. Expression of activation markers on CD4+ and CD8+ cells from synovial fluid, synovial tissue and peripheral blood of patients with inflammatory arthritides. Scand J Immunol 1989; 29: 631–9
  • Smiley J D, Sachs C, Ziff M. In vitro synthesis of immunoglobulin by rheumatoid synovial membrane. J Clin Invest 1968; 47: 624–32
  • Munthe E, Natvig JB. Immunoglobulin classes, subclasses and complexes of IgG rheumatoid factor in rheumatoid plasma cells. Clin Exp Immunol 1972; 12: 55–70
  • Egeland T, Lea T, Mellbye O J, Pahle J A, Ottesen T, Natvig JB. Quantitation of cells secreting immunoglobulins after elution from synovial tissue. Scand J Immunol 1982; 16: 413–9
  • Al-Balaghi S, Strøm H, Møller E. High incidence of spontaneous Ig-producing lymphocytes in peripheral blood and synovial fluid of patients with active seropositive rheumatoid arthritis. Scand J Immunol 1982; 16: 69–76
  • Kishimoto T, Hirano T. Molecular regulation of B lymphocyte response. Ann Rev Immunol 1988; 6: 485–512
  • Kehrl J H, Muraguchi A, Butler J L, Falkoff R JM, Fauci AS. B cell activation, proliferation and differentiation. Immunol Rev 1984; 78: 75–96
  • Takatsu K, Tominaga A, Harada N, et al. T-cell replacing factor (TRF)/Interleukin 5 (IL-5): Molecular and functional properties. Immunol Rev 1988; 102: 107–35
  • Defrance T, Vanbervliet B, Aubry J-P, et al. B-cell growth-promoting activity of recombinant human interleukin 4. J Immunol 1987; 139: 1135–41
  • Romagnani S, Giudizi M G, Biagiotti R, et al. B cell growth factor activity of interferon-gamma. Recombinant human interferon-gamma promotes proliferation of anti-μ-activated human B lymphocytes. J Immunol 1986; 136: 3513–6
  • Defrance T, Aubry J-P, Vanbervliet B, Banchereau J. Human interferon-gamma acts as a B cell growth factor in the anti-IgM antibody co-stimulatory assay but has no direct B cell differentiation activity. J Immunol 1986; 137: 3861–7
  • Mingari M C, Gerosa F, Carra G, et al. Human interleukin-2 promotes proliferation of activated B cells via surface receptors similar to those of activated T cells. Nature 1984; 312: 641–3
  • Sharma S, Mehta S, Morgan J, Maizel A. Molecular cloning and expression of a human B cell growth factor gene in Escherichia coli. Science 1987; 135: 1489–91
  • Gurney M E, Apatoff B R, Spear G T, et al. Neuroleukin: A lymphokine product of lectin-stimulated T cells. Science 1986; 234: 574–81
  • Hovdenes J, Gaudernack G, Kvien T K, Egeland T, Mellbye OJ. A functional study of purified CD4+ and CD8+ cells isolated from synovial fluid of patients with rheumatoid arthritis and other arthritides. Scand J Immunol 1989; 29: 641–9
  • Hovdenes J, Egeland T. Immunoregulatory lymphokines in rheumatoid joints. II. Production by and responsiveness to interleukin-2 of eluted synovial tissue cells. Rheumatol Int 1987; 7: 261–5
  • Abrahamsen T G, Frøland S S, Natvig JB. In vitro mitogen stimulation of synovial fluid lymphocytes from rheumatoid arthritis and juvenile rheumatoid arthritis patients: dissociation between the response to antigens and polyclonal mitogens. Scand J Immunol 1978; 7: 81–90
  • Hepburn B, McDuffie F C, Ritts RE. Impaired blastogenesis of lymphocytes from synovial fluid and peripheral blood of patients with rheumatoid arthritis. J Rheumatol 1976; 3: 118–23
  • Burmester G R, Kalden J R, Peter H H, Schedel I, Beck P, Wittenborg A. Immunological and functional characteristics of peripheral blood and synovial fluid lymphocytes from patients with rheumatoid arthritis. Scand J Immunol 1978; 7: 405–17
  • Hovdenes J, Gaudernack G, Kvien T K, Hovdenes A B, Egeland T. Mitogen-induced IL-2 and IFN-x production by CD4+ and CD8+ cells of patients with inflammatory arthritides. A comparison between cells from synovial fluid and peripheral blood. Scand J Immunol, in press
  • Sanders M E, Makgoba M W, Sharrow S O, et al. Human memory T lymphocytes express increased levels of three other molecules (UCHL1, CDw29 and Pgp-1) and have enhanced IFN- production. J Immunol 1988; 140: 1401–7
  • Emery P, Gentry K C, MacKay I R, Muirden K D, Rowly M. Deficiency of the suppressor inducer subset of T lymphocytes in rheumatoid arthritis. Arthritis Rheum 1987; 30: 849–56
  • Hovdenes J, Lund H, Lea T, Egeland T. Immunoregulatory lymphokines in rheumatoid joints. III. B cell growth promoting activity of cells eluted from rheumatoid synovial tissue. Scand J Rheumatol 1988; 17: 371–8
  • Bøyum A. Separation of blood leukocytes, granulocytes and lymphocytes. Tissue Antigens 1974; 4: 269–74
  • Lea T, Smeland E, Funderud S, et al. Characterization of human mononuclear cells after positive selection with immunomagnetic particles. Scand J Immunol 1986; 23: 509–19
  • Gaudernack G, Leivestad T, Ugelstad J, Thorsby E. Isolation of pure functionally active CD8+ T cells. Positive selection with monoclonal antibodies directly conjugated to monosized magnetic microspheres. J Immunol Methods 1986; 90: 179–87
  • Zola H. The surface antigens of human B lymphocytes. Immunol Today 1987; 8: 308–15
  • Smeland E, Funderud S, Ruud E, Blomhoff H K, Godal T. Characterisation of two murine monoclonal antibodies reactive with human B cells. Their use in a high-yield, high-purity method for isolation of B cells and the utilisation of such cells in an assay for B cell stimulating factor. Scand J Immunol 1985; 21: 201–14
  • Morimoto C, Letvin N L, Boyd A W, et al. The isolation and characterization of the human helper inducer T cell subset. J Immunol 1985; 134: 3762–9

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