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Original Article

Role of Micro-organisms in the Pathogenesis of Arthritis: Lessons from Reactive and Lyme Arthritis

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Pages 191-197 | Published online: 12 Jul 2009

References

  • Weyand C M, Goronzy JJ. Immune responses to Borrelia burgdorferi in patients with reactive arthritis. Arthritis Rheum 1989; 32: 1057–64
  • Toivanen A. Infection and arthritis. Ann Med 1994; 26: 245–8
  • Toivanen P, Toivanen A. Does Yersinia induce autoim-munity?. Int Arch Allergy Immunol 1994; 4: 107–11
  • Konttinen Y T, Nordström D C, Bergroth V, Leirisalo-Rep M, Santavirta S. Occurrence of different ensuing triggering infections preceding reactive arthritis A follow up study. Br Med J 1988; 296: 1644–5
  • Toivanen A, Granfors K, Lahesmaa-Rantala R, Leino R, Stiullberg T, Vuento R. Pathogenesis of Yersinia-triggered reactive arthritis: immunological, microbiological and clinical aspects. Immunol Rev 1985; 86: 47–70
  • Feltkamp T EW. The pathogenetic role of HLA-B27. Scand J Rheumatol 1990; 1–163, Suppl 87
  • Jardetzky T S, Lane W S, Robinson R A, Madden D R, Wiley DC. Identification of self peptides bound to purified HLA-B27. Nature 1991; 353: 326–9
  • Tertti R, Toivanen P. Immune functions and inflammatory reactions in HLA-B27 positive subjects. Ann Rheum Dis 1991; 50: 731–4
  • Hermann E, Yu D TY, Meyer zum Büschenfelde K-H, Fleischer B. HLA-B27-restricted CD8 T cells derived from synovial fluids of patients with reactive arthritis and ankylosing spondylitis. Lancet 1993; 342: 646–50
  • Toivanen P, Koskimies S, Granfors K, Eerola E. Bacterial antibodies in HLA-B27+ healthy individuals. Arthritis Rheum 1993; 36: 1633–5
  • Steere A C, Dwyer E, Winchester R. Association of chronic Lyme arthritis with HLA-DR4 and HLA-DR2 alleles. N Engl J Med 1990; 323: 219–23
  • Kalish R A, Leong J M, Steere AC. Association of treatment-resistant chronic Lyme arthritis with HLA-DR4 and antibody reactivity to OspA and OspB of Borrelia burgdorferi. Infect Immun 1993; 61: 2774–9
  • Saario R, Toivanen A. Chlamydia pneumoniae as a cause of reactive arthritis. Br J Rheumatol 1994; 33: 1112
  • Braun J, Laitko S, Treharne J, Eggens U, Wu P, Distler A, et al. Chlamydia pneumoniae — a new causative agent of reactive arthritis and undifferentiated oligoarthritis. Ann Rheum Dis 1994; 53: 100–5
  • Toivanen A, Granfors K, Lahesmaa-Rantala R, Toivanen P. Immunological and bacteriological aspects of reactive arthritis. Rheumatol Int 1989; 9: 201–3
  • Hoogkamp-Korstanje J A, de Koning J, Heesemann J. Persistence of Yersinia enterocolitica in man. Infection 1988; 16: 81–5
  • Burmester GR. Lessons from Lyme arthritis. Clin Exp Rheumatol 1993; 11: S23–7, Suppl. 8
  • Nocton J J, Dressler Rutledge B J, Rys P N, Persing D, Steere H. AC. Detection of Borrelia burgdorferi DNA by polymerase chain reaction in synovial fluid from patients with Lyme arthritis. N Engl J Med 1994; 330: 229–34
  • Weber K, Pfister H-W. Clinical management of Lyme borreliosis. Lancet 1994; 343: 1017–20
  • Merilahti-Palo R, Gripenberg-Lerche C, Söderström K O, Toivanen P. Long term follow up of SHR rats with experimental yersinia associated arthritis. Ann Rheum Dis 1992; 51: 91–6
  • Gripenberg-Lerche C, Toivanen P. Yersinia associated arthritis in SHR rats: effect of the microbial status of the host. Ann Rheum Dis 1993; 52: 223–8
  • Granfors K, Jalkanen S, Mäkid-Ikola O, Toivanen P. Bacterial antigens in reactive arthritis: studies on Yersinia-and Salmonella-triggered arthritis. HLA-B27+ Spondyloarthropathies, P E Lipsky, J D Taurog. Elsevier, New York 1991; 107–14
  • Hughes R, Keat A. Reactive arthritis: the role of bacterial antigens in inflammatory arthritis. Baillièe's Clin Rheumatol 1992; 6: 285–308
  • Toivanen P. Microorganisms and the locomotor system. Rheumatology, J H Klippel, P A Dieppe. Mosby, London 1993; 2.1–2.16, Section 4
  • Toivanen A. Reactive arthritis. Rheumatology, JH. Klippel, P A Dieppe. Mosby, London 1993; 9.1–9.8, Section 4
  • Toivanen A, Toivanen P. Is rheumatoid arthritis an infectious disease?. Rheumatology Up-date, E Asensi, P. Barceló, 1995, in press
  • Viitanen A M, Arstila T P, Lahesmaa R, Granfors K, Skurnik M, Toivanen P. Application of the polymerase chain reaction and immunofluorescence techniques to the detection of bacteria in Yersinia-eiggered reactive arthritis. Arthritis Rheum 1991; 34: 89–96
  • Nikkari S., Merilahti-Palo R, Saario R, Söderström K-O, Granfors K, Skurnik M, et al. Yersinia-triggered reactive arthritis: use of polymerase chain reaction and immuno-cytochemical staining in the detection of bacterial components from synovial specimens. Arthritis Rheum 1992; 35: 682–7
  • Schachter J, Barnes M G, Jones JP, Jr, Engleman E P, Meyer KF. Isolation of Bedsoniae from the joints of patients with Reiter's syndrome. Proc Soc Exp Biol Med 1966; 122: 283–5
  • Vilppula A H, Yli-Kerttula U I, Ahlroos A K, Terho PE. Chlamydial isolations and serology in Reiter's syndrome. Scand J Rheumatol 1981; 10: 181–5
  • Snydman D R, Schenkein D P, Berardi V P, Lastavica C C, Pariser KM. Borrelia burgdorferi in joint fluid in chronic Lyme arthritis. Ann Intern Med 1986; 104: 798–800
  • Schmidli J, Hunziker T, Moesli P, Schaad UB. Cultivation of Borrelia burgdorferi from joint fluid three months after treatment of facial palsy due to Lyme borreliosis. J Infect Dis 1988; 158: 905–6
  • Taylor-Robinson D, Gilroy C B, Thomas B J, Keat AC. Detection of Chlamydia trachomatis DNA in joints of reactive arthritis patients by polymerase chain reaction. Lancet 1992; 340: 81–2
  • Rahman M U, Cheema M A, Schumacher H R, Hudson AP. Molecular evidence for the presence of chlamydia in the synovium of patients with Reiter's syndrome. Arthritis Rheum 1992; 35: 521–9
  • Hammer M, Nettelnbreker E, Hopf S, Schmitz E, Wrschke K, Zeidler H. Chlamydial rRNA in the joints of patients with Chlamydia-induced arthritis and undifferen-tiated arthritis. Clin Exp Rheumatol 1992; 10: 63–6
  • Schmitz E, Nettelnbreker E, Zeidler H, Hammer M, Manor E, Wollenhaupt J. Intracellular persistence of chlamydial major outer-membrane protein, lipopolysac-charide and ribosomal RNA after non-productive infection of human monocytes with Chlamydia trachomatis serovar K. J Med Microbiol 1993; 38: 278–85
  • Wordsworth B P, Hughes R A, Allan I, Keat A C, Bell JI. Chlamydial DNA is absent from the joints of patients with sexually acquired reactive arthritis. Br J Rheumatol 1990; 29: 208–10
  • Poole E S, Highton J, Wilkins R J, Laurent IR. A search for Chlamydia trachomatis in synovial fluids from patients with reactive arthritis using the polymerase chain reaction and antigen detection methods. Br J Rheumatol 1992; 31: 31–4
  • Highton J, Poole E. Sexually acquired reactive arthritis: inflammation or sepsis?. BrJ Rheumatol 1993; 32: 649–52
  • Wordsworth BP. Should we treat postvenereal Reiter's syndrome by antibiotics?. J Rheumatol 1993; 20: 907
  • Schumacher H R, Hudson A P, Bardin T. Should we treat postvenereal Reiter's syndrome by antibiotics? Reply. J Rheumatol 1993; 20: 907–8
  • Goupille P, Fouquet B, Favard L, Burdin P, Valat J-P. Two cases of plant thorn synovitis Difficulties in diagnosis and treatment. J Rheumatol 1990; 17: 252–4
  • Silver R M, Sahn E E, Allen J A, Sahn S, Greene W, Maize J C, et al. Demonstration of silicon in sites of connective-tissue disease in patients with silicone-gel breast implants. Arch Dermatol 1993; 129: 63–8
  • Germain BF. Silicone breast implants and rheumatic disease. EULAR Bull 1993; 3: 94–6
  • Toivanen P, Toivanen A, Olkkonen L, Aantaa S. Hospital outbreak of Yersinia enterocolitica infection. Lancet 1973; 1: 801–3
  • Bennett G A, Shaffer MF. The passage of protein from the vascular system into joints and certain other body cavities. J Exp Med 1939; 70: 277–91
  • Shaffer M F, Bennett GA. The passage of type III rabbit virulent pneumococci from the vascular system into joints and certain other body cavities. J Exp Med 1939; 70: 293–302
  • Cooke T DV. Antigen-induced arthritis, polyarthritis, and tenosynovitis. Handbook of Animal Models for the Rheumatic Diseases., R A Greenvald, H S Diamond. CRC Press, Inc., Boca Raton, FL 1988; 53–81
  • Mertz A KH, Batsford S R, Curschellas E, Kist M J, Gon-Dolf KB. Cationic Yersinia antigen-induced chronic allergic arthritis in rats — a model for reactive arthritis in humans. J Clin Invest 1991; 87: 632–42
  • Ford D K, Da Roza D M, Schulzer M. Lymphocytes from the site of disease but not blood lymphocytes indicate the cause of arthritis. Ann Rheum Dis 1985; 44: 701–10
  • Gaston J SH, Life P F, Granfors K, Merilahti-Palo R, Bailey L, Consalvey S, et al. Synovial T lymphocyte recognition of organisms that trigger reactive arthritis. Clin Exp Immunol 1989; 76: 348–53
  • Keat A C, Knight SC. Do synovial fluid cells indicate the cause of reactive arthritis?. J Rheumatol 1990; 17: 1257–9
  • Life P F, Viner N J, Bacon P A, Gaston J SH. Synovial fluid antigen-presenting cells unmask peripheral blood T cell responses to bacterial antigens in inflammatory arthritis. Clin Exp Immunol 1990; 79: 189–94
  • Sieper J, Braun J, Wu P, Kingsley G. T cells are responsible for the enhanced synovial cellular immune response to triggering antigen in reactive arthritis. Clin Exp Immunol 1993; 91: 96–102
  • Choy E HS, Chieco-Bianchi F, Panayi G S, Kingsley GH. Synovial fluid lymphocyte proliferation to tuberculin protein product derivative: a novel way of diagnosing tuberculous arthritis. Clin Exp Rheumatol 1994; 12: 187–90
  • Hermann E, Lohse A W, van der Zee R, Van Eden W, Mayet W J, Probst P, et al. Synovial fluid-derived Yersinia-reactive T cells responding to human 65-kDa heat-shock protein and heat-stressed antigen-presenting cells. Eur J Immunol 1991; 21: 2139–43
  • Viner N J, Bailey L C, Life P F, Bacon P A, Gaston J SH. Isolation of Yersinia-specific T cell clones from the synovial membrane and synovial fluid of a patient with reactive arthritis. Arthritis Rheum 1991; 34: 1151–7
  • Hermann E, Lohse A W, Mayet W J, van der Zee R, Van Eden W, Probst P, et al. Stimulation of synovial fluid mononuclear cells with the human 65-kD heat shock protein or with live enterobacteria leads to preferential expansion of TCR-+ lymphocytes. Clin Exp Immunol 1992; 89: 427–33
  • Lahesmaa R, Skurnik M, Toivanen P. Molecular mimicry: any role in the pathogenesis of spondyloarthropathies?. Immunol Res 1993; 12: 193–208
  • Hermann E. T cells in reactive arthritis. APMIS 1993; 101: 177–86
  • Lahesmaa R, Yssel H, Batsford S, Luukkainen R, Mottonen T, Steinman L, et al. Yersinia enterocolitica activates a T helper type 1-like T cell subset in reactive arthritis. J Immunol 1992; 148: 3079–85
  • Schlaak J, Hermann E, Ringhoffer M, Probst P, Gallati H. Meyer zum Buschenfelde KH, et al Predominance of Thl-type T cells in synovial fluid of patients with yersinia-induced reactive arthritis. Eur J Immunol 1992; 22: 2771–6
  • Madden D R, Gorga J C, Strominger J L, Wiley DC. The three-dimensional structure of HLA-B27 at 2.1 Å resolution suggests a general mechanism for tight peptide binding to MHC. Cell 1992; 70: 1035–48
  • Guo H C, Madden D R, Silver M L, Jardetzky T S, Gorga J C, Strominger J L, et al. Comparison of the P2 specificity pocket in three human histocompatibility antigens: HLA-A*6801, and HLA-B*2705. Proc Natl Acad Sci USA 1993; 90: 8053–7
  • Skurnik M, Batsford S, Mertz A, Schiltz E, Toivanen P. The putative arthritogenic cationic 19-kilodalton antigen of Yersinia enterocolitica is a urease β-subunit. Infect Immun 1993; 61: 2498–504
  • Probst P, Hermann E, Meyer zum Büschenfelde K-H, Fleischer B. Identification of the Yersinia enterocolitica urease β-subunit as a target antigen for human synovial T lymphocytes in reactive arthritis. Infect Immun 1993; 61: 4507–9
  • Toivanen A, Toivanen P. Epidemiologic aspects, clinical features, and management of ankylosing spondylitis and reactive arthritis. Cum Opin Rheumatol 1994; 6: 354–9

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