Factors affecting wound healing after major amputation for vascular disease: A review

References

• Adera H M, James K, Castronuovo J J, Byrne M, Deshmukh R, lohr J. Prediction of amputation wound healing with skin perfusion pressure. J Vasc Surg 1995; 21: 823–829
   PubMed Web of Science ®Google Scholar
• Alter A, Moshein Z, Elconin K B, Cohen M J. Below-knee amputation using the sagittal technique. Clin Orthop 1978; 131: 195–201
   Google Scholar
• Ameli F M, Stein M, Provan J L, Prosser R. The effect of postoperative smoking on femoropopliteal bypass grafts. Ann Vasc Surg 1989; 3: 20–25
   PubMedGoogle Scholar
• Bailey M J, Yates C JP, Johnston C LW, Somerville P G, Dormandy J A. Preoperative haemoglobin as predictor of outcome of diabetic amputations. Lancet 1979; 2: 168–170
   PubMed Web of Science ®Google Scholar
• Baker W H, Barnes R W, Shurr D C. The healing of below-knee amputations. Am J Surg 1977; 133: 716–718
   PubMed Web of Science ®Google Scholar
• Barber G G, McPhail N V, Scobie T K, Brennan M C, llis C C. A prospective study of lower limb amputations. Can J Surg 1983; 26: 339–341
   PubMed Web of Science ®Google Scholar
• Barnes R W, Shanik G D, Slaymaker E E. An index of healing in below-knee amputation: leg blood pressure by Doppler ultrasound. Surgery 1976; 79: 13–20
   PubMed Web of Science ®Google Scholar
• Bartlett S T, Blaisdell F W. Is there a case for early amputation for critical ischaemia?. Limb salvage and amputation for vascular disease., R M Greenhalgh, C W Jamieson, A N. Nicolaides. WB Saunders, Philadelphia 1988; 389–395
   Google Scholar
• Basore C, Lewis M L. Wound healing in lower extremity amputation and a system for amputation prevention. Semin Perioper Nurs 1993; 2: 248–255
   Google Scholar
• Berardi R S, Keonin Y. Amputations in peripheral vascular occlusive disease. Am J Surg 1978; 135: 231–234
   PubMed Web of Science ®Google Scholar
• Birkenstock W E, Louw J H, Terblanche J, Immelman E J, Dent D M, Baker P M. Smoking and other factors affecting the conservative management of peripheral vascular disease. S Afr Med J 1975; 49: 1129–1132
   Google Scholar
• Borssén B, Lithner F. Amputations in diabetics and non-diabetics in Umeå County 1971–1977. Acta Med Scand (Suppl) 1983; 687: 95–100
   Google Scholar
• Bunt T J, Manship L L, Bynoe R PH, Haynes J L. Lower extremity amputation for peripheral vascular disease. A low-risk operation. Am Surg 1984; 50: 581–584
   Google Scholar
• Burgess E M, Matsen F A, Wyss C R, Simmons C W. Segmental transcutaneous measurements of pO2 in patients requiring below-the-knee amputation for peripheral vascular insufficiency. J Bone Joint Surg 1982; 64A: 378–382
   Google Scholar
• Burgess E M, Romano R L, Zettl J H, Schrock R D. Amputations of the leg for peripheral vascular insufficiency. J Bone Joint Surg 1971; 53A: 874–890
   Google Scholar
• Burgess E M., Zettl J H. Amputations below me knee. Artif Limbs 1969; 13: 1–12
   PubMedGoogle Scholar
• Campbell W B, St Johnston J A, Kernick V F, Rutter E A. Lower limb amputation: striking the balance. Ann R Coll Surg Engl 1994; 76: 205–209
   PubMed Web of Science ®Google Scholar
• Cederholm T. Protein-energy malnutrition in chronic disease: clinical and immunological studies in elderly subjects with non-malignant disorders. Thesis, Karolinska Institute, StockholmSweden 1994
   Google Scholar
• Centers For Disease Control. The Surgeon General's 1989 report of reducing the health consequences of smoking: 25 years of progress (Executive summary). MMWR 1989; 38(Suppl 2)1–32
   Google Scholar
• Christensen S. Lower extremity amputations in the county of Aalborg 1961–1971. Acta Orthop Scand 1976; 47: 329–334
   PubMed Web of Science ®Google Scholar
• Condie E, Jones D, Treweek S, Scott H. A one-year national survey of patients having a lower limb amputation. Physiotherapy 1996; 82: 14–20
   Google Scholar
• Cook T A, Davies A H, Horrocks M, Baird R N. Amputation level is not adversely affected by previous femoro-distal bypass surgery. Eur J Vasc Surg 1992; 6: 599–601
   Google Scholar
• Couch N P, David J K, Tilney N L, Crane C. Natural history of the leg amputee. Am J Surg 1977; 133: 469–473
   PubMed Web of Science ®Google Scholar
• dardik H, kahn M, dardik I, sussman B, ibrahim I M. Influence of failed vascular bypass procedures on conversion of below-knee to above-knee amputation levels. Surgery 1982; 91: 64–69
   PubMedGoogle Scholar
• Dean R H, Yao J S, Thompson R G, Bergan J J. Predictive value of ultrasonically derived arterial pressure in determination of amputation level. Am Surg 1975; 41: 731–737
   PubMed Web of Science ®Google Scholar
• Delmi M, Rapin C H, Bengoa J M, Delmas P D, Vasey H, Bonjour J P. Dietary supplementation in elderly patients with fractured neck of the femur. Lancet 1990; 1: 1013–1016
   Google Scholar
• Dickhaut S C, Delee J C, Page C P. Nutritional status: importance in predicting wound-healing after amputation. J Bone Joint Surg 1984; 66A: 71–75
   Google Scholar
• Dormandy J A, Belcher G, Broos P, Eikelboom B, Lazslo G, Konrad P, Moggi L, Mueller U. Prospective study of 713 below-knee amputations for ischaemia and the effect of a prostacyclin analogue on healing. Br J Surg 1994; 81: 33–37
   PubMedGoogle Scholar
• Dormandy J A, Ray S A. The fate of amputees. Vase Med Rev 1994; 5: 331–346
   Google Scholar
• Dwars B J, Van Den Broek T A, Rauwerda J A, Barker F C. Criteria for reliable selection of the lowest level of amputation in peripheral vascular disease. J Vasc Surg 1992; 15: 536–542
   Google Scholar
• Ebskov L B, Schroeder T V, Holstein P E. Epidemiology of leg amputation: the influence of vascular surgery. Br J Surg 1994; 81: 1600–1603
   PubMed Web of Science ®Google Scholar
• Eickhoff J H. Changes in the number of lower limb amputations during a period of increasing vascular surgical activity: results of a nation-wide study, Denmark, 1977–1990. Eur J Surg 1993; 159: 469–473
   PubMedGoogle Scholar
• Ek A C, Unosson M, Larsson J, Von Schenk H, Bjurulf P. The development and healing of pressure sores related to the nutritional state. Clin Nutr 1991; 10: 245–250
   PubMed Web of Science ®Google Scholar
• Eneroth M. Amputation for vascular disease: prognostic factors for healing. long-term outcome and costs. Thesis, Lund University, Sweden 1997
   Google Scholar
• Eneroth M, Apelqvist J, Larsson J, Persson B M. Improved wound healing in transtibial amputees receiving supplementary nutrition. Int Orthop 1997; 21: 104–108
   PubMed Web of Science ®Google Scholar
• Eneroth M, Persson B M. Amputation for occlusive arterial disease. Int Orthop 1992; 16: 383–387
   PubMed Web of Science ®Google Scholar
• Eneroth M, Persson B M. Risk factors for failed healing in amputation for vascular disease: a prospective consecutive study of 177 cases. Acta Orthop Scand 1993; 64: 369–372
   PubMed Web of Science ®Google Scholar
• Epstein S B, Worth M H, El Ferzli G. Level of amputation following failed vascular reconstruction for lower limb ischemia. Curr Surg 1989; 46: 185–192
   Google Scholar
• Ernst E, Matrai A, Kollar L. Placebo-controlled, double-blind study of haemodilution in peripheral arterial disease. Lancet 1987; 1: 1449–1451
   PubMed Web of Science ®Google Scholar
• Evans W E, Hayes J P, Vermilion B D. Effect of a failed distal reconstruction on the level of amputation. Am J Surg 1990; 160: 217–220
   PubMedGoogle Scholar
• Falstie-Jensen N, Christensen K S. A model for prediction of failure in amputation of the lower limb. Dan Med Bull 1990; 37: 283–286
   PubMedGoogle Scholar
• Falstie-Jensen N, Christensen K S, Brøchner-Mortensen J. Long posterior flap versus equal sagittal flaps in below-knee amputation for ischemia. J Bone Joint Surg 1989; 71B: 102–104
   Google Scholar
• Falstie-Jensen N, Christensen K S, Brøchner-Mortensen J. Selection of lower limb amputation level not aided by transcutaneous pO2 measurements. Acta Orthop Scand 1989; 60: 483–485
   PubMed Web of Science ®Google Scholar
• Fearon J, Campbell D R, Hoar C S, Gibbons G W, Rowbotham J L, Wheelock F C. Improved results with diabetic below-knee amputations. Arch Surg 1985; 120: 777–780
   PubMedGoogle Scholar
• Fielding J E. Smoking: health effects and control. N Engl J Med 1985; 313: 491–498, 555–561
   PubMed Web of Science ®Google Scholar
• Finch D RA, Macdougal M, Tibbs D J, Morris P J. Amputation for vascular disease: the experience of a peripheral vascular unit. Br J Surg 1980; 67: 233–237
   PubMed Web of Science ®Google Scholar
• Friis H. Penicillin G versus cefuroxime for prophylaxis in lower limb amputation. Acta Orthop Scand 1987; 58: 666–668
   PubMed Web of Science ®Google Scholar
• Fylling C P, Knighton D R. Amputation in the diabetic population: incidence, causes, cost, treatment and prevention. J Enterostomal Ther 1989; 16: 247–255
   PubMedGoogle Scholar
• Ghiulamila R I. Semi-rigid dressing for postoperative fitting of below-knee prosthesis. Arch Phys Med Rehabil 1972; 53: 186–190
   PubMed Web of Science ®Google Scholar
• Ghormley R K. Amputation in occlusive vascular disease. Peripheral vascular disease, V E Allen, N W Barker, E A Hines. WB Saunders, Philadelphia 1946; 783
   Google Scholar
• Gibbons G W, Marcaccio E J, Burgess A M, Pomposelli F B, Freeman D V, Campbell D R, Miller A, Logerfo F W. Improved quality of diabetic foot care, 1984 vs 1990. Reduced length of stay and costs, insufficient reimbursement. Arch Surg 1993; 128: 576–581
   PubMedGoogle Scholar
• Gibbons G W, Wheelock F C, Siembieda C, Hoar C S, Rowbotham J L, Persson A B. Noninvasive prediction of amputation level in diabetic patients. Arch Surg 1979; 114: 1253–1257
   PubMedGoogle Scholar
• Giddings A EB, Quaraishy M S, Walker W J. Long-term results of a single protocol for thrombosis in acute lower-limb ischaemia. Br J Surg 1993; 80: 1262–1265
   PubMedGoogle Scholar
• Gregg R O. Bypass or amputation? Concomitant review of bypass arterial grafting and major amputations. Am J Surg 1985; 149: 397–402
   PubMed Web of Science ®Google Scholar
• Hansen E S, Wethelund J O, Skajaa K. Hemoglobin and hematocrit as risk factors in below-the-knee amputation for incipient gangrene. Arch Orthop Trauma Surg 1988; 107: 92–95
   PubMed Web of Science ®Google Scholar
• Hansson J. The leg amputee: a clinical follow-up study. Acta Orthop Scand(Suppl) 1964; 35(Suppl 69)104
   Google Scholar
• Harris J P, Page S, Englund R, May J. Is the outlook for the vascular amputee improved by striving to preserve the knee?. J Cardiovasc Surg 1988; 29: 741–745
   PubMed Web of Science ®Google Scholar
• Harrison J D, Southworth D, Callum K G. Experience with the “skew-flap” below-knee amputation. Br J Surg 1987; 74: 930–931
   Google Scholar
• Haydock D A, Hill G L. Improved wound healing response in surgical patients receiving intravenous nutrition. Br J Surg 1987; 74: 320–323
   Google Scholar
• Hierton T, James U. Lower extremity amputation in Uppsala county 1947–1969: incidence and prosthetic rehabilitation. Acta Orthop Scand 1973; 44: 573–582
   PubMed Web of Science ®Google Scholar
• Holloway G A, Burgess E M. Preliminary experiences with laser Doppler velocimetry for the determination of amputation levels. Prosthet Orthot Int 1983; 7: 63–66
   PubMed Web of Science ®Google Scholar
• Holstein P. Distal blood pressure as guidance in choice of amputation level. Scand J Clin Lab Invest 1973; 31(Suppl 128)245–248
   Google Scholar
• Holstein P, Dovey H, Lassen N A. Wound healing in below-knee amputations in relation to skin perfusion pressure. Acta Orthop Scand 1979; 50: 49–58
   PubMed Web of Science ®Google Scholar
• Holstein P. Level selection in leg amputation for arterial occlusive disease: a comparison of clinical evaluation and skin perfusion pressure. Acta Orthop Scand 1982; 53: 821–831
   PubMed Web of Science ®Google Scholar
• Hughson W G, Mann J I, Garrod A. Intermittent claudication: prevalence and risk factors. Br Med J 1978a; 1: 1379–1381
   PubMedGoogle Scholar
• Hughson W G, Mann J I, Tibbs D J, Woods H F, Walton I. Intermittent claudication: factors determining outcome. Br Med J 1978b; 1: 1377–1379
   PubMedGoogle Scholar
• Huizinga W K, Robbs J V, Kritzinger N A. Peri-operative antibiotic cover in amputations using a amoxycillin-clavulanic acid combination. S Afr Med J 1982; 62: 13A–15A
   Google Scholar
• Huizinga W K, Robbs J V, Kritzinger N A. Prevention of wounds sepsis in amputations by peri-operative antibiotic cover with an amoxycillin-clavulanic acid combination. S Afr Med J 1983; 63: 71–73
   PubMed Web of Science ®Google Scholar
• Jain A S, Stewart C PU, Turner M S. Trans-tibial amputation using a medially based flap. J R Coll Surg Edinb 1995; 40: 263–265
   PubMedGoogle Scholar
• Jeans W D, Cole S EA, Horrocks M, Baird R N. Angioplasty gives good results in critical lower limb ischaemia. A 5-year follow-up in patients with known ankle pressure and diabetic status having femero-popliteal dilations. Br J Radiol 1994; 67: 123–128
   Google Scholar
• Jensen J E, Jensen T G, Smith T K, Johnston D A, Dudrick S J. Nutrition in orthopaedic surgery. J Bone Joint Surg 1982; 64A: 1263–1272
   Google Scholar
• Jensen Steen J, Mandroup-Poulsen T, Krasnik M. Wound healing complications following major amputations of the lower limb. Prosthet Orthot Int 1982; 6: 105–107
   PubMed Web of Science ®Google Scholar
• Jonason T, Bergström R. Cessation of smoking in patients with intermittent claudication. Effects of the risk of peripheral vascular complications, myocardial infarction and mortality. Acta Med Scand 1987; 221: 253–260
   PubMed Web of Science ®Google Scholar
• Jones L E. Lower limb amputation in three Australian States. Int Disabil Stud 1990; 12: 37–40
   PubMedGoogle Scholar
• Juergens J, Barker H, Hines E. Atherosclerosis obliterans: review of 520 cases with special reference to pathogenic and prognostic factors. Circulation 1960; 21: 188–195
   PubMed Web of Science ®Google Scholar
• Jörneskog G, Brismar K, Fagrell B. Low molecular weight heparin seems to improve local capillary circulation and healing of chronic foot ulcers in diabetic patients. Vasa 1993; 22: 137–142
   Google Scholar
• Kacy S S, Wolma F J, Flye M W. Factors affecting the results of below-knee amputation in patients with and without diabetes. Surg Gynecol Obstet 1982; 155: 513–518
   PubMedGoogle Scholar
• Kald A, Carlsson R, Nilsson E. Major amputation in a defined population: incidence, mortality and results of treatment. Br J Surg 1989; 76: 308–310
   PubMed Web of Science ®Google Scholar
• Kannel W B, McGee D, Gordon T. A general cardiovascular risk profile: the Framingham Study. Am J Cardiol 1986; 38: 46–51
   Google Scholar
• Karanfilian R G, Lynch T G, Zirul V T, Padberg F T, Jamil Z, Hobson R W. The value of laser Doppler velocimetry and transcutaneous oxygen tension determination in predicting healing of ischemic forefoot ulcerations and amputations in diabetic and non-diabetic patients. J Vasc Surg 1986; 4: 511–516
   PubMed Web of Science ®Google Scholar
• Kay S P, Moreland J R, Schmitter E. Nutritional status and wound healing in lower extremity amputations. Clin Orthop 1987; 217: 253–256
   PubMedGoogle Scholar
• Kazmers M, Satiani B, Evans W E. Amputation level following unsuccessful distal limb salvage operations. Surgery 1980; 87: 683–687
   PubMed Web of Science ®Google Scholar
• Keagy B A, Schwartz J A, Kotb M, Burnham S J, Johnson G jr. Lower extremity amputation: the control series. J Vasc Surg 1986; 4: 321–326
   PubMed Web of Science ®Google Scholar
• Krupski W C. The peripheral vascular consequences of smoking. Ann Vasc Surg 1991; 5: 291–304
   PubMedGoogle Scholar
• Lantsberg L, Goldman M. Laser Doppler flowmetry, transcutaneous oxygen tension measurements and Doppler pressure compared in patients undergoing amputation. Eur J Vasc Surg 1991; 5: 195–197
   Google Scholar
• Larsson J, Apelqvist J. Towards less amputations in diabetic patients: incidence, causes, treatment and prevention - a review. Acta Orthop Scand 1995; 66: 181–192
   PubMed Web of Science ®Google Scholar
• Larsson J, Apelqvist J, Agardh C D, strenström A. Decreasing incidence of major amputation in diabetic patients: a consequence of multidisciplinary foot care team approach?. Diabet Med 1995; 12: 770–776
   PubMed Web of Science ®Google Scholar
• Larsson P A, Risberg B. Amputations due to lower-limb ischaemia: analysis of a 3-year series. Acta Chir Scand 1988; 154: 267–270
   PubMedGoogle Scholar
• Lassila R, Lepäntalo M. Cigarette smoking and the outcome after lower limb arterial surgery. Acta Chir Scand 1988; 154: 635–640
   PubMedGoogle Scholar
• Lepäntalo M, Isoniemi H, Kyllönen L. Can the failure of a below-knee amputation be predicted?: predictability of below-knee amputation healing. Ann Chir Gynaecol 1987; 76: 119–123
   PubMedGoogle Scholar
• Levin M E, O'neal L W, Bowker J H. The diabetic foot5th edition. Mosby Year Book, St Louis 1993
   Google Scholar
• Liedberg E, Persson B M. Age, diabetes and smoking in lower limb amputation for arterial occlusive disease. Acta Orthop Scand 1983; 54: 383–388
   PubMed Web of Science ®Google Scholar
• Liedberg E, Persson B M. Increased incidence of lower limb amputation for arterial occlusive disease. Acta Orthop Scand 1983; 54: 230–234
   PubMed Web of Science ®Google Scholar
• Lind J, Kramhøft M, Bødker S. The influence of smoking on complications after primary amputations of the lower extremity. Clin Orthop 1991; 267: 211–217
   Google Scholar
• Lindblad B, Sternby N H, Bergqvist D. Incidence of venous thromboembolisim verified by necropsy over 30 years. Br Med J 1991; 302: 709–711
   PubMed Web of Science ®Google Scholar
• Lindholt J S, Bøvling S, Fasting H, Henneberg E W. Vascular surgery reduces the frequency of lower limb major amputations. Eur J Vasc Surg 1994; 8: 31–35
   PubMedGoogle Scholar
• Luther M. The influence of arterial reconstructive surgery on the outcome of critical leg ischaemia. Eur J Vasc Surg 1994; 8: 682–689
   PubMedGoogle Scholar
• Lääperi T, Pohjolainen T, Alaranta H, Kärkäinen M. Lower-limb amputations. Ann Chir Gynaecol 1993; 82: 183–187
   PubMedGoogle Scholar
• Maclean N, Fick G H. The effect of semi-rigid dressings on below-knee amputations. Phys Ther 1994; 74: 668–673
   PubMedGoogle Scholar
• Malone J M, Leal J M, Moore W S, Henry R E, Daly M J, Patton D D, Childers S J. The “Gold Standard” for amputation level selection: Xenon-133 clearance. J Surg Res 1981; 30: 449–455
   PubMed Web of Science ®Google Scholar
• Mandrup-Poulsen T, Jensen J. Incidence of major amputations following gangrene of the lower limb. Prosthet Orthot Int 1982; 6: 35–37
   PubMed Web of Science ®Google Scholar
• McCollum P T, Spence V A, Walker W F. Amputation of peripheral vascular disease: the case for level selection. Br J Surg 1988; 75: 1193–1195
   PubMedGoogle Scholar
• McCollum P T, Spence V A, Walker W F, Swanson A JG, Turner M S, Murdoch G. Experience the healing rate of lower limb amputations. J R Coll Surg Edinb 1984; 29: 358–362
   Google Scholar
• McCollum P T, Walker W F. Major limb amputation for end-stage peripheral vascular disease: level selection and alternative options. Atlas of limb prosthetics: surgical, prosthetic, and rehabilitation principles./2nd edition./American Academy of Orthopaedic Surgeons, J H Bowker, J W. Michael. Mosby Year Book, St Louis 1992; 25–38
   Google Scholar
• McMillan D E. The microcirculation in diabetes. Microcirc Endothelium Lymphatics 1984; 1: 3–24
   Google Scholar
• McWhinney D L, Gordon A C, Collin J, Gray D WR, Morrison J D. Rehabilitation outcome 5 years after 100 lower-limb amputations. Br J Surg 1994; 81: 1596–1599
   Google Scholar
• Messmer K, Sunder-Plassman L, Von Hesler H, Endrich B. Hemodilution in peripheral occlusive disease: a hemorheological approach. Clin Hemorheol 1982; 2: 721–731
   Google Scholar
• Midthjell K, Bjorndahl A, Holmen J, Kruger O, Bjarteveit K. Prevalence of known and previously unknown diabetes mellitus and impaired glucose tolerance in an adult Norwegian population. Indications of an increasing diabetes prevalence. The Nord Trondelag Diabetes Study. Scared J Prim Health Care 1995; 13: 229–235
   PubMed Web of Science ®Google Scholar
• Møller B N, Krebs B. Antibiotic prophylaxis in lower limb amputation. Acta Orthop Scand 1985; 56: 327–329
   PubMedGoogle Scholar
• Mooney V, Harvey J P, Jr, McBride E, Snelson R. Comparison of postopertaive stump management: plaster vs soft dressings. J Bone Joint Surg 1971; 53A: 241–249
   Google Scholar
• Moss S E, Klein R, Klein B. The prevalence and incidence of lower extremity amputation in a diabetic population. Arch Intern Med 1992; 152: 610–615
   PubMed Web of Science ®Google Scholar
• Myers K A, King R B, Scott D F, Johnson N, Morris P J. The effect of smoking on the late patency of arterial reconstruction in the legs. Br J Surg 1978; 65: 267–271
   PubMed Web of Science ®Google Scholar
• Nelson R G, Gohdes D M, Everhart J E, Hartner J A, Zwemer F L, Pettitt D J, Knowler W C. Lower extremity amputations in NIDDM: 12 yr follow-up study in Pima Indians. Diabetes Care 1988; 11: 8–16
   PubMed Web of Science ®Google Scholar
• Netz P, Stark A, Ringertz H. Amputations for vascular insufficiency. Prosthet Orthot Int 1983; 7: 9–14
   PubMed Web of Science ®Google Scholar
• Nicholas G G, Demuth W E. Evaluation of use of the rigid dressing in amputation of the lower extremity. Surg Gynecol Obstet 1976; 143: 398–400
   PubMedGoogle Scholar
• Oishi C S, Fronek A, Golbranson F L. The role of non-invasive vascular studies in determining levels of amputation. J Bone Joint Surg 1988; 70A: 1520–1530
   Google Scholar
• Older M WJ, Edwards D, Dickerson J WT. A nutrient survey in elderly women with femoral neck fractures. Br J Surg 1980; 67: 884–886
   PubMed Web of Science ®Google Scholar
• Padberg F T, Back T L, Thompson P N, Hobson R W. Transcutaneous oxygen (TcPO2) estimates probability of healing in the ischemic extremity. J Surg Res 1996; 60: 365–369
   Web of Science ®Google Scholar
• Panayiotopoulos Y P, Reidy J F, Taylor P R. The concept of knee salvage: why does a failed femorocrural/pedal arterial bypass not affect the amputation level?. Eur J Vasc Endovasc Surg 1997; 13: 477–485
   Google Scholar
• Pedersen A E, Bornefeldt Olsen B, Krasnik M, Ebskov L B, Leicht B P, Sager P, Helgestrand U, Holstein P. Halving the number of leg amputations: the influence of infrapopliteal bypass. Eur J Vasc Surg 1994; 8: 26–30
   PubMedGoogle Scholar
• Pedersen N W, Pedersen D. Nutrition as a prognostic indicator in amputations. Acta Orthop Scand 1992; 63: 675–678
   PubMedGoogle Scholar
• Pell J P, Donnan P T, Fowkes F GR, Ruckley C V. Quality of life following lower limb amputation for peripheral arterial disease. Eur J Vasc Surg 1993; 7: 448–451
   PubMedGoogle Scholar
• Pell J P, Fowkes F GR, Ruckley C V, Clarke J, Kendrick S, Boyd J H. Declining incidence of amputation for arterial disease in Scotland. Eur J Vasc Surg 1994; 8: 602–606
   PubMedGoogle Scholar
• Persson B M. Sagittal incision for below-knee amputation in ischaemic gangrene. J Bone Joint Surg 1974; 56B: 110–114
   Google Scholar
• Persson B M, Bereiter H, Liedberg E. Lower leg amputation with sagittal section in vascular diseases -a study of 692 patients. Beitr Orthop Traumatol 1981; 28: 656–663
   Google Scholar
• Persson B M, Liedberg E, Eneroth M. Break of trend for lower extremity amputation in diabetic patients. J Swedish Med Assoc 1989; 28–29, 2523–2524 (In Swedish)
   Google Scholar
• Pohjolainen T, Alaranta H. Lower limb amputations in Southern Finland 1984–1985. Prosthet Orthot Int 1988; 12: 9–18
   PubMed Web of Science ®Google Scholar
• Pollock S B, Ernst C B. Use of Doppler pressure measurements in predicting success in amputation of the leg. Am J Surg 1980; 139: 303–306
   PubMed Web of Science ®Google Scholar
• Pomposelli F B, Marcaccio E J, Gibbons G W, Campbell D R, Freeman D V, Burgess A M, Miller A, Legerfo F W. Dorsalis pedis arterial bypass: durable limb salvage for foot ischemia in patients with diabetes mellitus. J Vasc Surg 1995; 21: 375–384
   PubMed Web of Science ®Google Scholar
• Porter J M, Baur G M, Taylor L M. Lower extremity amputations for ischemia. Arch Surg 1981; 116: 89–92
   Google Scholar
• Quick C R, Cotton L T. The measured effect of stopping smoking on intermittent claudication. Br J Surg 1982; 69: S24–26
   PubMedGoogle Scholar
• Raines J K, Darling R C, Buth J, Brewster D C, Austen W G. Vascular laboratory criteria for the management of peripheral vascular disease on the lower extremities. Surgery 1976; 79: 21–29
   PubMed Web of Science ®Google Scholar
• Reiber G E, Pecoraro R E, Koepsell T D. Risk factors for amputation in patients with diabetes mellitus: a case-control study. Ann Int Med 1992; 117: 97–105
   PubMed Web of Science ®Google Scholar
• Reus W F, Robson M C, Zachary L, Heggers J P. Acute effects of tobacco smoking on blood flow in the cutaneous micro-circulation. Br J Plastic Surg 1984; 37: 213–215
   PubMedGoogle Scholar
• Robbs J V, Kritzinger N A, Mogotlane K A, Odell J A., Huizinga W H. A clinical trial of a combination of amoxycillin and flucloxacillin in amputations for septic ischaemic lower limb lesions. Afr Med J 1981; 60: 932–934, S
   Google Scholar
• Robbs J V, Ray R. Clinical predictors of below-knee stump healing following amputation for ischaemia. S Afr J Surg 1982; 20: 305–310
   Google Scholar
• Robinson K P, Hoile R, Coddington T. Skew flap myoplastic below-knee amputation: a preliminary report. Br J Surg 1982; 69: 554–557
   PubMed Web of Science ®Google Scholar
• Ruckley C V, Stonebridge P A, Prescott R J. Skew flap versus long posterior flap in below-knee amputations: multicentre trial. J Vasc Surg 1991; 13: 423–427
   PubMedGoogle Scholar
• Samson R H, Gupta S K, Scher L A, Veith F J. Level of amputation after failure of limb salvage procedures. Surg Gynecol Obstet 1982; 154: 56–58
   PubMedGoogle Scholar
• Sarin C L, Austin J C, Nickel W O. Effects of smoking on digital blood-flow velocity. JAMA 1974; 229: 1327–1328
   PubMed Web of Science ®Google Scholar
• Sarin S, Shami S, Shields D A, Scurr J H, Coleridge Smith P D. Selection of amputation level: a review. Eur J Vasc Surg 1991; 5: 611–620
   PubMedGoogle Scholar
• Schwartz J A, Schuler J J, O'connor R J, Flanigan D P. Predictive value of distal perfusion pressure in the healing of amputation of the digtis and the forefoot. Surg Gynecol Obstet 1982; 154: 865–869
   Google Scholar
• Second European Consensus Document on Chronic Critical Leg Ischemia. Circulation 1991; 84(Suppl IV)1–26
   Google Scholar
• Selby J V, Zhang D. Risk factors for lower extremity amputation in persons with diabetes. Diabetes Care 1995; 18: 509–516
   PubMed Web of Science ®Google Scholar
• Sernbo I, Johnell O, Nilsson-Å J, Nilsson M. Primary, major amputations in Malmö, Sweden from 1979, 1984, 1989 and 1994. An effort to study changes in incidence and characteristics of the patients (Abstract). Swedish Orthopedic Association, annual meeting, Karstad, 1996; 34
   Google Scholar
• Sethia K K, Berry A R, Morrison J D, Collin J, Murie J A, Morris P J. Changing pattern of lower limb amputation for vascular disease. Br J Surg 1986; 73: 701–703
   PubMed Web of Science ®Google Scholar
• Shah D M, Darling C, Chang B B, Kaufman J L, Fitzgerald K M, Leather R P. In long vein bypass from groin to ankle a durable procedure? An analysis of a ten-year experience. J Vasc Surg 1992; 15: 402–408
   PubMedGoogle Scholar
• Siitonen O I, Niskanen L K, Laakso M, Siitonen J T, Pyöralä K. Lower-extremity amputations in diabetic and non-diabetic patients: a population-based study in eastern Finland. Diabetes Care 1993; 16: 16–20
   PubMed Web of Science ®Google Scholar
• Sonne-Holm S, Boeckstyns M, Menck H, Sinding A, Leicht P, Dichmann O, Brorson Prag J, Baekgaard N, Ostri P, Goetrik J K. Prophylactic antibiotics in amputation of the lower extremity for ischemia: a placebo-controlled, randomised trial of cefoxitin. J Bone Joint Surg 1985; 67A: 800–803
   Google Scholar
• Stachnik T, Hoppe R. The smoking problem. Public Health Rev 1986; 14: 115–138
   Google Scholar
• Stenström A, Larsson J, Apelqvist J. Decreasing numbers and lower levels of amputation -a preliminary 10-year report (abstract). Acta Orthop Scand 1992; 63(Suppl 248)194
   Google Scholar
• Stewart C P. The influence of smoking on the level of lower limb amputation. Prosthet Orthot Int 1987; 11: 113–116
   PubMed Web of Science ®Google Scholar
• Stirnemann P, Mlinaric Z, Oesch A, Kirchhof B, Althaus U. Major lower extremity amputation in patients with peripheral arterial insufficiency with special reference to transgenicular amputation. J Cardiovasc Surg 1987; 28: 152–158
   PubMedGoogle Scholar
• Stirnemann P, Walpoth B, Würsten H U, Graber P, Parli R, Althaus U. Influence of failed arterial reconstruction on the outcome of major limb amputation. Surgery 1992; 111: 363–368
   PubMedGoogle Scholar
• Termansen N B. Below-knee amputation for ischaemic gangrene: prospective, randomised comparison of a transverse and sagittal operative technique. Acta Orthop Scand 1977; 48: 311–316
   PubMed Web of Science ®Google Scholar
• Thomsen S, Jakobsen W, Wethelund J O, Dalsgaard J, Gregersen H N, Lucht U. Antibiotic prophylaxis in lower-extremity amputations due to ischemia: a prospective, randomised trial of cephalothin versus methicillin. Arch Orthop Trauma Surg 1990; 109: 72–74
   Google Scholar
• Tracy G D. Below-knee amputation for ischemic gangrene. Pac Med Surg 1966; 74: 251–253
   PubMedGoogle Scholar
• Tripses D, Pollak E W. Risk factors in healing of below-knee amputation: appraisal of 64 amputations in patients with vascular disease. Am J Surg 1981; 141: 718–720
   PubMed Web of Science ®Google Scholar
• Tsang G MK, Crowson M C, Hickey N C, Simms M H. Failed femorocrural reconstruction does not prejudice amputation level. Br J Surg 1991; 78: 1479–1481
   PubMed Web of Science ®Google Scholar
• Unosson M. Malnutrition in hospitalised elderly patients. Thesis, University of Linköping, LinköpingSweden 1993
   Google Scholar
• Van Adrichem L NA, Hovious Ser, Van Strik R, Van Der Meulen J C. Acute effects of cigarette smoking in microcirculation of the thumb. Br J Plast Surg 1992; 45: 9–11
   PubMedGoogle Scholar
• Vanbuskirk A, Barta P J, Schlossbach N J. Lower extremity amputations in New Jersey. N J Med 1994; 91: 260–263
   Google Scholar
• Wagner W H, Keagy B A, Kotb M M, Burnham S J, Johnson G. Noninvasive determination of healing of major lower extremity amputation: the continued role of clinical judgement. J Vasc Surg 1988; 8: 703–710
   Google Scholar
• Wahlberg E, Lepner U, Olofsson P. Limb loss in association with vascular surgery - a five-year series of major lower-limb amputation. Eur J Surg 1994; 160: 561–567
   PubMedGoogle Scholar
• Warnold I, Lundholm K. Clinical significance of preoperative nutritional status in 215 non-cancer patients. Ann Surg 1984; 199: 299–305
   PubMed Web of Science ®Google Scholar
• Weiss G N, Gorton T A, Read R C, Neal L A. Outcomes of lower extremity amputations. J Am Geriatr Soc 1990; 38: 877–883
   PubMed Web of Science ®Google Scholar
• Wetterhall S F, Olson D R, Destefano F, Stevenson J M, Ford E S, German R R, Will J C, Newman J M, Sepe S J, Vinicor F. Trends in diabetes and diabetic complications, 1980–1987. Diabetes Care 1992; 15: 960–967
   PubMed Web of Science ®Google Scholar
• White S A, Thompson M M, Zickerman A M, Broomhead P, Critchley P, Barrie W W, Bell P R. Lower limb amputation and grade of surgeon. Br J Surg 1997; 84: 509–511
   Google Scholar
• Wutschert R, Bounameaux H. Determination of amputation level in ischemic limbs: reappraisal of the measurement of TcPo2. Diabetes Care 1997; 20: 1315–1318
   PubMedGoogle Scholar
• Wyss C R, Harrington R M, Burgess E M, Matsen F A. Transcutaneous oxygen tension as a predictor of success after an amputation. J Bone Joint Surg 1988; 70A: 203–207
   Google Scholar
• Yates C J, Berent A, Andrews V, Dormandy J A. Increase in leg blood-flow by normovolaemic haemodilution in intermittent claudication. Lancet 1979; 2: 166–168
   PubMed Web of Science ®Google Scholar