Spectrum of α-Globin Gene Mutations in the Kerman Province of Iran

REFERENCES

• Chong SS, Boehm CD, Higgs DR, Single-tube multiplex-PCR screen for common deletional determinants of α-thalassemia. Blood. 2000;95(1):360–362.
   PubMed Web of Science ®Google Scholar
• Kan YW. Molecular pathology of α-thalassemia. Ann NY Acad Sci. 1985;445(5):28–36.
   Google Scholar
• Higgs DR, Vickers MA, Wilkie AO, A review of the molecular genetics of the human α-globin gene cluster. Blood. 1989;73(5):1081–1104.
   PubMed Web of Science ®Google Scholar
• Kazazian HH Jr. The thalassemia syndrome: molecular basis and prenatal diagnosis in 1990. Semin Hematol. 1990; 27(3): 209–228.
   PubMed Web of Science ®Google Scholar
• Orkin SH, Old JM, Lazarus H, The molecular basis of α-thalassemias: frequent occurrence of dysfunctional α loci among non-Asians with Hb H disease. Cell. 1979;17(1):33–42.
   Google Scholar
• Hadavi V, Taromachi AH, Malekpour M, Eluciding the spectrum of α-thalassemia mutations in Iran. Haematologica. 2007;92(7): 992–993.
   PubMedGoogle Scholar
• Neishabury M, Abbasi-Moheb L, Poorfathollah A, α-Thalassemia: deletion analysis in Iran. Arch Irn Med. 2001;4(4):160–164.
   Google Scholar
• Higgs DR, Steinberg MH, Forget BG, Molecular mechanisms of α-thalassemia. In: Steinberg MH, Ed. Disorders of Hemoglobin; Genetics; Pathophysiology, and Clinical Management. Cambridge: Cambridge University Press. 2001:405–430.
   Google Scholar
• Harteveld CL, Refaldi C, Cassinerio E, Segmental duplications involving the α-globin gene cluster are causing β-thalassemia intermedia phenotypes in β-thalassemia heterozygous patients. Blood Cells Mol Dis. 2008;40(3):312–316.
   PubMed Web of Science ®Google Scholar
• Giordano PC, Bakker-Verwij M, Harteveld CL. Frequency of α-globin gene triplications and their interaction with β-thalassemia mutations. Hemoglobin. 2009;33(2):124–131.
   PubMed Web of Science ®Google Scholar
• Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988;16(3):1215.
   PubMed Web of Science ®Google Scholar
• Oron-Karni V, Filon D, Oppenheim A, Rund D. Rapid detection of the common Mediterranean α-globin deletions/rearrangements using PCR. Am J Hematol. 1998;58(4):306–310.
   PubMed Web of Science ®Google Scholar
• Garshasbi M, Oberkanins C, Law HY, α-Globin gene deletion and point mutation analysis among in Iranian patients with microcytic hypochromic anemia. Haematologica. 2003;88(10):1196–1197.
   PubMed Web of Science ®Google Scholar
• Shaji RV, Srivastava A, Chandy M, A single tube multiplex PCR method to detect the common α+ thalassemia alleles. Blood. 2000:95(5):1879–1880.
   PubMed Web of Science ®Google Scholar
• Ko TM, Hwa HL, Liu CW, Prevalence study and molecular characterization of α thalassemia in Filipinos. Ann Hematol. 1999;78(8):355–357.
   PubMed Web of Science ®Google Scholar
• Hadavi V, Jafroodi M, Hafezi-Nejad N, α-Thalassemia mutations in Gilan Province, North Iran. Hemoglobin. 2009; 33(3):235–241.
   PubMed Web of Science ®Google Scholar
• Tamaddoni A, Hadavi V, Nejad NH, α-Thalassemia mutation analyses in Mazandaran Province, North Iran. Hemoglobin. 2009; 33(2):115–123.
   PubMed Web of Science ®Google Scholar
• Harteveld CL, Yavarian M, Zorai A, Molecular spectrum of α-thalassemia in the Iranian population of Hormozgan: three novel point mutation defects. Am J Hematol. 2003;74(2):99–103.
   PubMed Web of Science ®Google Scholar
• Zandian K, Nateghi J, Keikhaie B, α-Thalassemia mutations in Khuzestan Province, Southwest Iran. Hemoglobin. 2008;32(6):546–552.
   PubMed Web of Science ®Google Scholar
• Oner C, Gurgey A, Oner R, The molecular basis of Hb H disease in Turkey. Hemoglobin. 1997;21(1):41–51.
   PubMed Web of Science ®Google Scholar
• Gallanelo R, Aru B, Dessì C, Hb H disease in Sardinia: molecular, hematological and clinical aspects. Acta Haematol. 1992; 88(1):1–6.
   Google Scholar
• Traeger-Synodinos J, Kanavakis E, Vrettou C, The triplicated α-globin gene locus in β-thalassaemia heterozygotes: clinical, haematological, biosynthetic and molecular studies. Br J Haematol. 1996;95(3):467–471.
   PubMed Web of Science ®Google Scholar
• Camaschella C, Kattamis AC, Petroni D, Different hematological phenotypes caused by the interaction of triplicated α-globin genes and heterozygous β-thalassemia. Am J Hematol. 1997;55(2):83–88.
   PubMed Web of Science ®Google Scholar
• Weatherall DJ. The molecular basis of thalassemia. Johns Hopkins Med J. 1976;139(5):205–210.
   Google Scholar
• Harteveld CL, Voskamp A, Phylipsen M. Nine unknown rearrangements in 16p13.3 and 11p15.4 causing α- and β-thalassaemia characterized by high resolution multiplex ligation-dependent probe amplification. J Med Genet. 2005;42(12):922–931.
   PubMed Web of Science ®Google Scholar