Permeation studies on freshly excised rat gastric mucosa: influence of pH

References

• Akiyama Y, Nagahara N, Nara E, Kitano M, Iwasa S, Yamamoto I, Azuma J, Ogawa Y. (1998). Evaluation of oral mucoadhesive microspheres in man on the basis of the pharmacokinetics of furosemide and riboflavin, compounds with limited gastrointestinal absorption sites. J Pharm Pharmacol 50:159–166.
   PubMed Web of Science ®Google Scholar
• Ashley SW, Soybel DI, Moore CD, Cheung LY. (1987). Intracellular pH (pHi) in gastric surface epithelium is more susceptible to serosal than mucosal acidification. Surgery 102:371–379.
   PubMed Web of Science ®Google Scholar
• Bernkop-Schnürch A, Reich-Rohrwig E, Marschütz M, Schuhbauer H, Kratzel M. (2004). Development of a sustained release dosage form for alpha-lipoic acid. II. Evaluation in human volunteers. Drug Dev Ind Pharm 30:35–42.
   PubMed Web of Science ®Google Scholar
• Craig PN. (1990). Drug Compendium, in Cumulative Subject Index & Drug Compendium (Drayton CJ, ed), Vol. 6, pp. 237–991, Pergamon Press, Oxford.
   Google Scholar
• Crespy V, Morand C, Besson C, Manach C, Demigne C, Remesy C. (2002). Quercetin, but not its glycosides, is absorbed from the rat stomach. J Agric Food Chem 50:618–621.
   PubMed Web of Science ®Google Scholar
• Da Violante G, Zerrouk N, Richard I, Provot G, Chaumeil JC, Arnaud P. (2002). Evaluation of the cytotoxicity effect of dimethyl sulfoxide (DMSO) on Caco2/TC7 colon tumor cell cultures. Biol Pharm Bull 25:1600–1603.
   PubMed Web of Science ®Google Scholar
• Dahan A, Amidon GL. (2009). Segmental dependent transport of low permeability compounds along the small intestine due to P-glycoprotein: the role of efflux transport in the oral absorption of BCS class III drugs. Mol Pharm 6:19–28.
   PubMed Web of Science ®Google Scholar
• DeSesso JM, Jacobson CF. (2001). Anatomical and physiological parameters affecting gastrointestinal absorption in humans and rats. Food Chem Toxicol 39:209–228.
   PubMed Web of Science ®Google Scholar
• Freshney RI. (2005). Culture of Animal Cells: A Manual of Basic Technique, 5th edition, p. 117, Wiley-Liss, New York.
   Google Scholar
• Iqbal T, Karyekar CS, Kinjo M, Ngan GC, Dowling TC. (2004). Validation of a simplified method for determination of cimetidine in human plasma and urine by liquid chromatography with ultraviolet detection. J Chromatogr B Analyt Technol Biomed Life Sci 799:337–341.
   PubMed Web of Science ®Google Scholar
• Karlarli T. (1989). Gastrointestinal absorption of drugs. Crit Rev Ther Drug Carrier Syst 6:39–86.
   PubMed Web of Science ®Google Scholar
• Kimura T, Higaki K. (2002). Gastrointestinal transit and drug absorption. Biol Pharm Bull 25:149–164.
   PubMed Web of Science ®Google Scholar
• Kromer W, Krüger U, Huber R, Hartmann M, Steinijans VW. (1998). Differences in pH-dependent activation rates of substituted benzimidazoles and biological in vitro correlates. Pharmacology 56:57–70.
   PubMed Web of Science ®Google Scholar
• Kwak HH, Kim JO, Chung HK, Choi SM, Kim JH, Kwon JW, Yoo M, Lee  JH, Lee MG. (2006). Pharmacokinetics of oral amlodipine orotate in vagotomized dogs. Biopharm Drug Dispos 27:141–145.
   PubMed Web of Science ®Google Scholar
• Luciano L, Reale E. (1992). The “limiting ridge” of the rat stomach. Arch Histol Cytol 55(Suppl):131–138.
   PubMed Web of Science ®Google Scholar
• Menon A, Ritschel WA, Sakr A. (1991). Biopharmaceutic evaluation of furosemide as a potential candidate for a modified release peroral dosage form. Methods Find Exp Clin Pharmacol 13:629–636.
   PubMed Web of Science ®Google Scholar
• Moazed B, Hiebert LM. (2009). Movement of heparins across rat gastric mucosa is dependent on molecular weight and pH. Pharm Res 26:189–195.
   PubMed Web of Science ®Google Scholar
• Mummaneni V, Amidon GL, Dressman JB. (1995). Gastric pH influences the appearance of double peaks in the plasma concentration-time profiles of cimetidine after oral administration in dogs. Pharm Res 12:780–786.
   PubMed Web of Science ®Google Scholar
• Palm K, Luthman K, Ros J, Grasjo J, Artursson P. (1999). Effect of molecular charge on intestinal epithelial drug transport: pH-dependent transport of cationic drugs. J Pharmacol Exp Ther 291:435–443.
   PubMed Web of Science ®Google Scholar
• Panchagnula R, Bansal T, Varma MV, Kaul CL. (2004). Reversed-phase liquid chromatography with ultraviolet detection for simultaneous quantitation of indinavir and propranolol from ex-vivo rat intestinal permeability studies. J Chromatogr B Analyt Technol Biomed Life Sci 806:277–282.
   PubMed Web of Science ®Google Scholar
• Passamonti S, Vrhovsek U, Vanzo A, Mattivi F. (2003). The stomach as a site for anthocyanins absorption from food. FEBS Lett 544:210–213.
   PubMed Web of Science ®Google Scholar
• Piskula MK, Yamakoshi J, Iwai Y. (1999). Daidzein and genistein but not their glucosides are absorbed from the rat stomach. FEBS Lett 447:287–291.
   PubMed Web of Science ®Google Scholar
• Pretorius E, Bouic PJ. (2009). Permeation of four oral drugs through human intestinal mucosa. AAPS PharmSciTech 10:270–275.
   PubMed Web of Science ®Google Scholar
• Romeis B. (1968). Mikroskopische Technik, 16th edition, §304, R. Oldenburg, München, Wien.
   Google Scholar
• Schulzke JD, Gitter AH, Mankertz J, Spiegel S, Seidler U, Amasheh S, Saitou M, Tsukita S, Fromm M. (2005). Epithelial transport and barrier function in occludin-deficient mice. Biochim Biophys Acta 1669:34–42.
   PubMed Web of Science ®Google Scholar
• Streubel A, Siepmann J, Bodmeier R. (2006). Gastroretentive drug delivery systems. Expert Opin Drug Deliv 3:217–233.
   PubMed Web of Science ®Google Scholar
• Takeuchi K, Magee D, Critchlow J, Matthews J, Silen W. (1983). Studies of the pH gradient and thickness of frog gastric mucus gel. Gastroenterology 84:331–340.
   PubMed Web of Science ®Google Scholar
• Thiebaut F, Tsuruo T, Hamada H, Gottesman MM, Pastan I, Willingham MC. (1987). Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci USA 84:7735–7738.
   PubMed Web of Science ®Google Scholar
• U.S. Pharmacopeia, 30. National Formulary 25, Vol. 1, p. 810.
   Google Scholar
• Varma MV, Ashokraj Y, Dey CS, Panchagnula R. (2003). P-glycoprotein inhibitors and their screening: a perspective from bioavailability enhancement. Pharmacol Res 48:347–359.
   PubMed Web of Science ®Google Scholar
• Wang Y, Zuo Z, Chen X, Tomlinson B, Chow MS. (2010). Improving sublingual delivery of weak base compounds using pH(max) concept: application to propranolol. Eur J Pharm Sci 39:272–278.
   PubMed Web of Science ®Google Scholar