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Research Article

Preparation and optimization of doxorubicin-loaded albumin nanoparticles using response surface methodology

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Pages 1170-1180 | Received 08 Oct 2010, Accepted 14 Feb 2011, Published online: 31 Mar 2011

References

  • Cho K, Wang X, Nie S, Chen ZG, Shin DM. (2008). Therapeutic nanoparticles for drug delivery in cancer. Clin Cancer Res, 14:1310–1316.
  • Singal PK, Li T, Kumar D, Danelisen I, Iliskovic N. (2000). Adriamycininduced heart failure: mechanism and modulation. Mol Cell Biochem, 207:77–86.
  • Minotti G, Menna P, Salvatorelli E, Cairo G, Gianni L. (2004). Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev, 56:185–229.
  • Gelperina SE, Khalansky AS, Skidan IN, Smirnova ZS, Bobruskin AI, Severin SE et al. (2002). Toxicological studies of doxorubicin bound to polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles in healthy rats and rats with intracranial glioblastoma. Toxicol Lett, 126:131–141.
  • Steiniger SC, Kreuter J, Khalansky AS, Skidan IN, Bobruskin AI, Smirnova ZS et al. (2004). Chemotherapy of glioblastoma in rats using doxorubicin-loaded nanoparticles. Int J Cancer, 109:759–767.
  • Cuvier C, Roblot-Treupel L, Millot JM, Lizard G, Chevillard S, Manfait M et al. (1992). Doxorubicin-loaded nanospheres bypass tumor cell multidrug resistance. Biochem Pharmacol, 44:509–517.
  • Leo E, Cameroni R, Forni F. (1999). Dynamic dialysis for the drug release evaluation from doxorubicin-gelatin nanoparticle conjugates. Int J Pharm, 180:23–30.
  • Yoo HS, Oh JE, Lee KH, Park TG. (1999). Biodegradable nanoparticles containing doxorubicin-PLGA conjugate for sustained release. Pharm Res, 16:1114–1118.
  • Plank C, Mechtler K, Szoka FC, Wagner E. (1996). Activation of the complement system by synthetic DNA complexes: A potential barrier for intravaneous gene delivery. Human Gene Ther, 7:1437–1446.
  • Orson FM, Kinsey BM, Hua PJ, Bhogal BS, Densmore CL, Barry MA. (2000). Genetic immunization with lung-targeting macroaggregated polyethyleneimine–albumin conjugates elicits combined systemic an mucosal immune responses. J Immunol, 164:6313–6321.
  • Orson FM, Song L, Gautam A, Densmore CL, Bhogal BS, Kinsey BM. (2002). Gene delivery to the lung using protein/polyethylenimine/plasmid complexes. Gene Ther, 9:463–471.
  • Truong-Le VL, Walsh SM, Schweibert E, Mao HQ, Guggino WB, August JT et al. (1999). Gene transfer by DNA-gelatin nanospheres. Arch Biochem Biophys, 361:47–56.
  • Simões S, Slepushkin V, Pires P, Gaspar R, Pedroso de Lima MC, Düzgünes N. (2000). Human serum albumin enhances DNA transfection by lipoplexes and confers resistance to inhibition by serum. Biochim Biophys Acta, 1463:459–469.
  • Weber C, Coester C, Kreuter J, Langer K. (2000). Desolvation process and surface characterisation of protein nanoparticles. Int J Pharm, 194:91–102.
  • Langer K, Balthasar S, Vogel V, Dinauer N, von Briesen H, Schubert D. (2003). Optimization of the preparation process for human serum albumin (HSA) nanoparticles. Int J Pharm, 257:169–180.
  • Nobs L, Buchegger F, Gurny R, Allémann E. (2004). Current methods for attaching targeting ligands to liposomes and nanoparticles. J Pharm Sci, 93:1980–1992.
  • Wartlick H, Michaelis K, Balthasar S, Strebhardt K, Kreuter J, Langer K. (2004). Highly specific HER2-mediated cellular uptake of antibody-modified nanoparticles in tumour cells. J Drug Target, 12:461–471.
  • Dinauer N, Balthasar S, Weber C, Kreuter J, Langer K, von Briesen H. (2005). Selective targeting of antibody-conjugated nanoparticles to leukemic cells and primary T-lymphocytes. Biomaterials, 26:5898–5906.
  • Steinhauser I, Spänkuch B, Strebhardt K, Langer K. (2006). Trastuzumab-modified nanoparticles: optimisation of preparation and uptake in cancer cells. Biomaterials, 27:4975–4983.
  • Gallo JM, Hung CT, Perrier DG. (1984). Analysis of albumin microsphere preparation. Int J Pharm, 22:63–74.
  • Lin W, Coombes AG, Davies MC, Davis SS, Illum L. (1993). Preparation of sub-100 nm human serum albumin nanospheres using a pH-coacervation method. J Drug Target, 1:237–243.
  • Müller BG, Leuenberger H, Kissel T. (1996). Albumin nanospheres as carriers for passive drug targeting: an optimized manufacturing technique. Pharm Res, 13:32–37.
  • Westcott CC. (1978). pH Measurements. New York, USA: Academic Press.
  • Kristo E, Biliaderis CG, Tzanetakis N. (2003). Modeling of the acidification process and rheological properties of milk fermented with a yogurt starter culture using response surface methodology. Food Chem, 83:437–446.
  • Beg QK, Saxena RK, Gupta R. (2002). Kinetic constants determination for an alkaline protease from Bacillus mojavensis using response surface methodology. Biotechnol Bioeng, 78:289–295.
  • Lai LST, Pan CC, Tzeng BK. (2003). The influence of medium design on lovastatin production and pellet formation with a high-producing mutant of Aspergillus terreus in submerged cultures. Process Biochem, 38:1317–1326.
  • Soo EL, Salieh AB, Basri M. (2004). Response surface methodological study on lipasecatalyzed synthesis of amino acid surfactants. Process Biochem, 39:1151–1518.
  • Wang YX, Lu ZX. (2005). Optimization of processing parameters for the mycelial growth and extracellular polysaccharide production by Boletus spp. ACCC 50328. Process Biochem, 40:1043–1051.
  • Preetha B, Viruthagiri T. (2007). Application of response surface methodology for the biosorption of copper using Rhizopus arrhizus. J Hazard Mater, 143:506–510.
  • Mannan S, Fakhrul-Razi A, Alam MZ. (2007). Optimization of process parameters for the bioconversion of activated sludge by Penicillium corylophilum, using response surface methodology. J Environ Sci (China), 19:23–28.
  • Chang JS, Tsai YH, Wu PC, Huang YB. (2007). The effect of mixed-solvent and terpenes on percutaneous absorption of meloxicam gel. Drug Dev Ind Pharm, 33:984–989.
  • Pan CM, Fan YT, Xing Y, Hou HW, Zhang ML. (2008). Statistical optimization of process parameters on biohydrogen production from glucose by Clostridium sp. Fanp2. Bioresour Technol, 99:3146–3154.
  • Shah SN, Asghar S, Choudhry MA, Akash MS, ur Rehman N, Baksh S. (2009). Formulation and evaluation of natural gum-based sustained release matrix tablets of flurbiprofen using response surface methodology. Drug Dev Ind Pharm, 35:1470–1478.
  • Liu CH, Wu CT, Fang JY. (2010). Characterization and formulation optimization of solid lipid nanoparticles in vitamin K1 delivery. Drug Dev Ind Pharm, 36:751–761.
  • Kim MS, Kim JS, You YH, Park HJ, Lee S, Park JS et al. (2007). Development and optimization of a novel oral controlled delivery system for tamsulosin hydrochloride using response surface methodology. Int J Pharm, 341:97–104.
  • Myers RH, Montgomery DC. (2002). Response Surface Methodology, 2nd Edition. New york, USA: John Wiley & Sons.
  • Harris PL, Cuppett SL, Bullerman LB. (1990). Optimization of lipase synthesis by Pseudomonas fluorescens by response surfacemethodology. J Food Protect, 53:481–483.
  • Lescure F, Zimmer C, Roy R, Couveur P. (1992). Optimization of poly(alkylcyanoacrylate) nanoparticles: influence of sulphur dioxide and pH on nanoparticles characteristics. J Colloid Interf Sci, 154:77–86.
  • Armstrong NA, James KC. (1990). Understanding Experimental Design and Interpretation in Pharmaceutics. Ellis Horwood, Chichester, UK.
  • Lin W, Garnett MC, Davis SS, Schacht E, Ferruti P, Illum L. (2001). Preparation and characterisation of rose Bengal-loaded surface-modified albumin nanoparticles. J Control Release, 71:117–126.
  • Haley B, Frenkel E. (2008). Nanoparticles for drug delivery in cancer treatment. Urol Oncol, 26:57–64.
  • Sun JX, Wang LN, Yin L, Zhang ZX. (2004). Determination of 10-hydroxycamptothecin in tissues of rats by HPLC-FD. J China Pharm Univ, 35:540–544.
  • Vergnaud JM. (1993). Controlled Drug Release of Oral Dosage Forms. Chicster, UK: Ellis Horwood.
  • Dhiman MK, Yedurkar PD, Sawant KK. (2008). Buccal bioadhesive delivery system of 5-fluorouracil: optimization and characterization. Drug Dev Ind Pharm, 34:761–770.

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