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Research Article

Development and evaluation of carvedilol-loaded transdermal drug delivery system: In-vitro and in-vivo characterization study

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Pages 1530-1537 | Received 15 Aug 2011, Accepted 03 Jan 2012, Published online: 23 Feb 2012

References

  • Chien YW. (1982a). Transdermal therapeutic system. In: Robinson JR ed Sustained and Controlled Release Drug Delivery Systems. New York: Marcel Dekker, 523.
  • Chien YW. (1982b). Novel drug delivery systems. In: Robinson JR ed Sustained and Controlled Release Drug Delivery Systems. New York: Marcel Dekker.
  • Keith AD. (1983). Polymer matrix consideration for transdermal devices. Drug Dev Ind Pharm, 9: 605–625
  • Rhine WD, Hsieh DST, Langer RJ. (1980). Kinetics of Polymeric delivery systems for proteins and other macromolecules. Pharm Sci, 69: 265–270.
  • Mollendorff EV, Reiff K, Neugebauer G. (1987). Pharmacokinetics and bioavailability of carvedilol: A vasodilating beta-blocker. Eur J Clin Pharm, 33:511–513.
  • Dollery C. (1999). Therapeutics Drugs. Edinburgh, UK: Churchill Livingstone, 75–80.
  • Chen YW. (1987). Transdermal therapeutic system. In Robinson JR, Lee VHL, eds Controlled Drug Delivery Fundamentals and Applications. 2nd ed. New York: Marcel Dekker, 524–552.
  • Bromberg L. (1996). Cross-linked poly (ethylene glycol) networks as reservoirs for protein delivery. J Appl Poly Sci, 59:459–466.
  • Ubaidulla U, Reddy MVS, Ruckmani K. (2007). Transdermal therapeutic system of carvedilol: Effect of hydrophilic and hydrophobic matrix on in vitro and in vivo characteristics, AAPS PharmSciTech, 8: Article 2.
  • Garala K, Shinde AJ. (2009). Formulation and in vitro characterization of monolithic matrix transdermal systems using HPML/eudragit S 100 polymer blends. Int J Pharm Pharm Sci, 1:108–117.
  • Gupta R, Mukherjee P. (2003). Development and in vitro evaluation of diltiazem HCL transdermal patches based on povidone-ethyl cellulose matrices. Drug Dev Ind Pharm, 29:1–7.
  • Arora P, Mukherjee P. (2002). Design, development, physiochemical, in vitro and in vivo evaluation of transdermal patches containing diclofenac diethyl ammonium salt. J Pharm Sci, 91:2076–2089.
  • Garala KC, Shinde AJ.(2008). Development and Characterization of Transdermal therapeutics system of tramadol hydrochloride. Asian J. Pharm, 2:265–269.
  • Agrawal SS, Munjal P. (2007). Permeation studies of atenolol and metoprolol tartrate from three different polymer matrices for transdermal delivery. Indian J Pharm Sci, 69:535–539.
  • Jain AK, Thomas S, Panchagnula R. (2002). Transdermal drug delivery of imipramine hydrochloride: I. Effect of terpenes. J Control Release, 79:93–101.
  • Shyamoshree B, Amal Kumar B. (2010). Development and characterization of mucoadhesive: In situ nasal gel of midazolam prepared with ficus carica mucilage. AAPS PharmSciTech, 11: 3, September.
  • Dixit AR, Rajput S. (2010). Preparation and bioavailability assessment of SMEDDS containing carvedilol. AAPS PharmSciTech, 11:314–321.
  • Draize JH, Woodward G. (1944). Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. J Pharmacol Exp Ther, 82:377–379.
  • Fujimaki M, Murakoshi Y, Hakusui H. (1990). Assay and disposition of Carvedilol enantiomers in humans and monkeys: Evidence of stereoselective presystemic metabolism. J Pharm Sci, 79:568–572.
  • Wade A, Weller PJ. (1994). Handbook of Pharmaceutical Excipients. Washington, DC: American Pharmaceutical Publishing Association, 362–366.
  • Mutalik S, Udupa N. (2004). Glibenclamide transdermal patches: Physicochemical, pharmacodynamic, and pharmacokinetic evaluations. J Pharm Sci, 93:1577–1594.

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