Self-emulsifying bifendate pellets: preparation, characterization and oral bioavailability in rats

References

• Wang XL, Yi MG, Liu ZM, Song ZY. (1983). [Absorption, distribution and excretion of biphenyl dimethyl-dicarboxylate (BDD)]. Yao Xue Xue Bao, 18:892–899.
   PubMedGoogle Scholar
• Liu GT. (1989). Pharmacological actions and clinical use of fructus schizandrae. Chin Med J, 102:740–749.
   PubMed Web of Science ®Google Scholar
• el-Sawy SA, el-Shafey AM, el-Bahrawy HA. (2002). Effect of dimethyl diphenyl bicarboxylate on normal and chemically-injured liver. East Mediterr Health J, 8:95–104.
   PubMedGoogle Scholar
• Cheng J, Wu ZH, Ping QN, Wang B, Lu J. (2010). The absorption characteristics of bifendate solid dispersion in rat intestinal tissue. Drug Dev Ind Pharm, 36:283–291.
   PubMed Web of Science ®Google Scholar
• Liu Y, Zhang D, Zou D, Wang Y, Duan C, Jia L et al. (2011). Development and in vitro characterizations of bifendate nanosuspensions. J Biomed Nanotechnol, 7:621–631.
   PubMed Web of Science ®Google Scholar
• Kim CK, Cho YJ, Gao ZG. (2001). Preparation and evaluation of biphenyl dimethyl dicarboxylate microemulsions for oral delivery. J Control Release, 70:149–155.
   PubMed Web of Science ®Google Scholar
• Tian X, Quan DQ. (2011). Assessment of a Supersaturated Self-Microemulsifying Formulation of Biphenyl Dimethyl Dicarboxylate in Vitro and in Vivo. Chin Pharm J, 46:600–604.
   Google Scholar
• Gursoy RN, Benita S. (2004). Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs. Biomed Pharmacother, 58:173–182.
   PubMed Web of Science ®Google Scholar
• Hong JY, Kim JK, Song YK, Park JS, Kim CK. (2006). A new self-emulsifying formulation of itraconazole with improved dissolution and oral absorption. J Control Release, 110:332–338.
   PubMed Web of Science ®Google Scholar
• Balakrishnan P, Lee BJ, Oh DH, Kim JO, Lee YI, Kim DD et al. (2009). Enhanced oral bioavailability of Coenzyme Q10 by self-emulsifying drug delivery systems. Int J Pharm, 374:66–72.
   PubMed Web of Science ®Google Scholar
• Yoo JH, Shanmugam S, Thapa P, Lee ES, Balakrishnan P, Baskaran R et al. (2010). Novel self-nanoemulsifying drug delivery system for enhanced solubility and dissolution of lutein. Arch Pharm Res, 33:417–426.
   PubMed Web of Science ®Google Scholar
• Nazzal S, Smalyukh II, Lavrentovich OD, Khan MA. (2002). Preparation and in vitro characterization of a eutectic based semisolid self-nanoemulsified drug delivery system (SNEDDS) of ubiquinone: mechanism and progress of emulsion formation. Int J Pharm, 235:247–265.
   PubMed Web of Science ®Google Scholar
• Newton M, Petersson J, Podczeck F, Clarke A, Booth S. (2001). The influence of formulation variables on the properties of pellets containing a self-emulsifying mixture. J Pharm Sci, 90:987–995.
   PubMed Web of Science ®Google Scholar
• Wang Z, Sun J, Wang Y, Liu X, Liu Y, Fu Q et al. (2010). Solid self-emulsifying nitrendipine pellets: preparation and in vitro/in vivo evaluation. Int J Pharm, 383:1–6.
   PubMed Web of Science ®Google Scholar
• Iosio T, Voinovich D, Grassi M, Pinto JF, Perissutti B, Zacchigna M et al. (2008). Bi-layered self-emulsifying pellets prepared by co-extrusion and spheronization: influence of formulation variables and preliminary study on the in vivo absorption. Eur J Pharm Biopharm, 69:686–697.
   PubMed Web of Science ®Google Scholar
• Franceschinis E, Voinovich D, Grassi M, Perissutti B, Filipovic-Grcic J, Martinac A et al. (2005). Self-emulsifying pellets prepared by wet granulation in high-shear mixer: influence of formulation variables and preliminary study on the in vitro absorption. Int J Pharm, 291:87–97.
   PubMed Web of Science ®Google Scholar
• Yi T, Wan J, Xu H, Yang X. (2008). A new solid self-microemulsifying formulation prepared by spray-drying to improve the oral bioavailability of poorly water soluble drugs. Eur J Pharm Biopharm, 70:439–444.
   PubMed Web of Science ®Google Scholar
• Chiellini EE, Bellich B, Macchiavelli S, Fiannaca R, Skrbec D, Cadelli GC, Carli F. (2003). Solid double microemulsions for improved absorption of scarcely bioavailable drugs. Farm Vestn, 54:469–470.
   Google Scholar
• Patel AR, Vavia PR. (2010). SMEDDS incorporated polymer matrix: a floating dosage form solution for drugs with poor gastric solubility. Pharm Technol, 22:36–42.
   Google Scholar
• Abdalla A, Mäder K. (2007). Preparation and characterization of a self-emulsifying pellet formulation. Eur J Pharm Biopharm, 66:220–226.
   PubMed Web of Science ®Google Scholar
• Rege BD, Kao JP, Polli JE. (2002). Effects of nonionic surfactants on membrane transporters in Caco-2 cell monolayers. Eur J Pharm Sci, 16:237–246.
   PubMed Web of Science ®Google Scholar
• Han SK, Kim GY, Park YH. (1999). Solubilization of biphenyl dimethyl dicarboxylate by cosolvency. Drug Dev Ind Pharm, 25:1193–1197.
   PubMed Web of Science ®Google Scholar
• Narang AS, Delmarre D, Gao D. (2007). Stable drug encapsulation in micelles and microemulsions. Int J Pharm, 345:9–25.
   PubMed Web of Science ®Google Scholar
• Pouton CW, Porter CJ. (2008). Formulation of lipid-based delivery systems for oral administration: materials, methods and strategies. Adv Drug Deliv Rev, 60:625–637.
   PubMed Web of Science ®Google Scholar
• Chen Y, Chen C, Zheng J, Chen Z, Shi Q, Liu H. (2011). Development of a solid supersaturatable self-emulsifying drug delivery system of docetaxel with improved dissolution and bioavailability. Biol Pharm Bull, 34:278–286.
   PubMed Web of Science ®Google Scholar
• Constantinides PP, Scalart JP, Lancaster C, Marcello J, Marks G, Ellens H et al. (1994). Formulation and intestinal absorption enhancement evaluation of water-in-oil microemulsions incorporating medium-chain glycerides. Pharm Res, 11:1385–1390.
   PubMed Web of Science ®Google Scholar
• Yap SP, Yuen KH. (2004). Influence of lipolysis and droplet size on tocotrienol absorption from self-emulsifying formulations. Int J Pharm, 281:67–78.
   PubMed Web of Science ®Google Scholar
• Wei L, Li J, Guo L, Nie S, Pan W, Sun P et al. (2007). Investigations of a novel self-emulsifying osmotic pump tablet containing carvedilol. Drug Dev Ind Pharm, 33:990–998.
   PubMed Web of Science ®Google Scholar
• Ghosh PK, Murthy RS. (2006). Microemulsions: a potential drug delivery system. Curr Drug Deliv, 3:167–180.
   PubMedGoogle Scholar
• Liu Y, Zhang P, Feng N, Zhang X, Wu S, Zhao J. (2009). Optimization and in situ intestinal absorption of self-microemulsifying drug delivery system of oridonin. Int J Pharm, 365:136–142.
   PubMed Web of Science ®Google Scholar
• Araya H, Tomita M, Hayashi M. (2005). The novel formulation design of O/W microemulsion for improving the gastrointestinal absorption of poorly water soluble compounds. Int J Pharm, 305:61–74.
   PubMed Web of Science ®Google Scholar
• Patel D, Sawant KK. (2009). Self micro-emulsifying drug delivery system: formulation development and biopharmaceutical evaluation of lipophilic drugs. Curr Drug Deliv, 6:419–424.
   PubMedGoogle Scholar
• Trevaskis NL, Charman WN, Porter CJ. (2008). Lipid-based delivery systems and intestinal lymphatic drug transport: a mechanistic update. Adv Drug Deliv Rev, 60:702–716.
   PubMed Web of Science ®Google Scholar
• O’Driscoll CM. (2002). Lipid-based formulations for intestinal lymphatic delivery. Eur J Pharm Sci, 15:405–415.
   PubMed Web of Science ®Google Scholar
• Dahan A, Hoffman A. (2007). The effect of different lipid based formulations on the oral absorption of lipophilic drugs: the ability of in vitro lipolysis and consecutive ex vivo intestinal permeability data to predict in vivo bioavailability in rats. Eur J Pharm Biopharm, 67:96–105.
   PubMed Web of Science ®Google Scholar
• Sha X, Yan G, Wu Y, Li J, Fang X. (2005). Effect of self-microemulsifying drug delivery systems containing Labrasol on tight junctions in Caco-2 cells. Eur J Pharm Sci, 24:477–486.
   PubMed Web of Science ®Google Scholar