83
Views
3
CrossRef citations to date
0
Altmetric
Research Article

The effect of lipid and aqueous solubilities on flux of nicotinic acid esters from water through silicone membrane

, &
Pages 1494-1497 | Received 29 Feb 2012, Accepted 13 May 2012, Published online: 08 Jun 2012

References

  • Roberts WJ, Sloan KB. (1999). Correlation of aqueous and lipid solubilities with flux for prodrugs of 5-fluorouracil, theophylline, and 6-mercaptopurine: A Potts-Guy approach. J Pharm Sci, 88:515–522.
  • Wasdo S, Juntunen J, Devarajan H, Murray T, Nickels D, Singh S et al. (2008). Modeling of flux through silicone membranes from water. Eur J Pharm Sci, 34:321–332.
  • Kasting GB, Smith RL, Cooper ER. (1987). Effect of lipid solubility and molecular size on percutaneous absorption.. In: Shroot B, Schaefer H, eds. Pharmacology and the Skin. Vol 1. Basel: Karger, 138–153.
  • Potts RO, Guy RH. (1992). Predicting skin permeability. Pharm Res, 9:663–669.
  • Pozzo AD, Donzelli G, Liggeri E, Rodriguez L. (1991). Percutaneous absorption of nicotinic acid derivatives in vitro. J Pharm Sci, 80:54–57.
  • Pozzo AD, Liggeri E, Delucca C, Calabrese G. (1991). Prediction of skin permeation of highly lipophilic compounds; in vitro model with a modified receptor phase. Int J Pharm, 70:219–223.
  • Le VH, Lippold BC. (1995). Influence of physics-chemical properties of homologous esters of nicotinic acid of skin permeability and maximum flux. Int J Pharm, 124:285–292.
  • Rittirod T, Hatanaka T, Kagami N, Katayama K, Koizumi T. (1999). Simultaneous transport and metabolism of nicotinic acid derivatives in hairless mouse skin. Biol Pharm Bull, 22:305–309.
  • Guy RH, Carlström EM, Bucks DA, Hinz RS, Maibach HI. (1986). Percutaneous penetration of nicotinates: In vivo and in vitro measurements. J Pharm Sci, 75:968–972.
  • Wasdo SC, Juntunen J, Devarajan H, Sloan KB. (2009). A correlation of flux through a silicone membrane with flux through hairless mouse skin and human skin in vitro. Int J Pharm, 373:62–67.
  • Magnusson BM, Anissimov YG, Cross SE, Roberts MS. (2004). Molecular size as the main determinant of solute maximum flux across the skin. J Invest Dermatol, 122:993–999.
  • Henning A, Schaefer UF, Neumann D. (2009). Potential pitfalls in skin permeation experiments: Influence of experimental factors and subsequent data evaluation. Eur J Pharm Biopharm, 72:324–331.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.