Advanced search
Publication Cover
Drug Development and Industrial Pharmacy Volume 39, 2013 - Issue 5
Submit an article Journal homepage
692
Views
22
CrossRef citations to date
0
Altmetric
Research Article

Gelucire 44/14 based immediate release formulations for poorly water-soluble drugs

André B. da Fonseca AntunesDepartment of Pharmaceutics, Laboratory of Pharmaceutical Technology, Ghent University, Harelbekestraat 72, 9000, Ghent, Belgium
,
Bruno G. De GeestDepartment of Pharmaceutics, Laboratory of Pharmaceutical Technology, Ghent University, Harelbekestraat 72, 9000, Ghent, BelgiumCorrespondence[email protected]
,
Chris VervaetDepartment of Pharmaceutics, Laboratory of Pharmaceutical Technology, Ghent University, Harelbekestraat 72, 9000, Ghent, Belgium
&
Jean Paul RemonDepartment of Pharmaceutics, Laboratory of Pharmaceutical Technology, Ghent University, Harelbekestraat 72, 9000, Ghent, Belgium
Pages 791-798 | Received 22 May 2012, Accepted 30 Jun 2012, Published online: 08 Aug 2012

References

  • U.S Departments of Health and Human Service – FDA. (1997). Guidance for Industry: Dissolution testing of immediate release solid oral dosage forms. Silver Spring: Center for Drug Evaluation and Research, Food and Drug Administration, US Departments of Health and Human Service. 2–6.
  • Dixit RP, Nagarsenker MS. (2008). Formulation and in vivo evaluation of self-nanoemulsifying granules for oral delivery of a combination of ezetimibe and simvastatin. Drug Dev Ind Pharm, 34:1285–1296.
  • Hu J, Johnston KP, Williams RO 3rd. (2004). Nanoparticle engineering processes for enhancing the dissolution rates of poorly water soluble drugs. Drug Dev Ind Pharm, 30:233–245.
  • Kim HJ, Yoon KA, Hahn M, Park ES, Chi SC. (2000). Preparation and in vitro evaluation of self-microemulsifying drug delivery systems containing idebenone. Drug Dev Ind Pharm, 26:523–529.
  • Ahuja N, Katare OP, Singh B. (2007). Studies on dissolution enhancement and mathematical modeling of drug release of a poorly water-soluble drug using water-soluble carriers. Eur J Pharm Biopharm, 65:26–38.
  • Dordunoo SK, Ford JL, Rubinstein MH. (1991). Preformulations studies on solid dispersions containing triamterene or temazepan in polyethykene glycols or Gelucire 44 14 for liquid filling of hard gelatin calsules. Drug Dev Ind Pharm, 17:1685–1713.
  • Chambin O, Jannin V. (2005). Interest of multifunctional lipid excipients: Case of Gelucire 44/14. Drug Dev Ind Pharm, 31:527–534.
  • Shimpi S, Chauhan B, Mahadik KR, Paradkar A. (2004). Preparation and evaluation of diltiazem hydrochloride-Gelucire 43/01 floating granules prepared by melt granulation. AAPS PharmSciTech, 5:e43.
  • de Barochez BH, Julien JS, Lapeyre F, Horvath S, Cuiné A. (1989). Influence of drug solubility in the formulation of hydrophilic matrices. Drug Dev Indus Pharm, 15:14–15.
  • Mehuys E, Vervaet C, Remon JP. (2004). Hot-melt extruded ethylcellulose cylinders containing a HPMC-Gelucire core for sustained drug delivery. J Control Release, 94:273–280.
  • El Massik MA, Abdallah OY, Galal S, Daabis NA. (2003). Semisolid matrix filled capsules: An approach to improve dissolution stability of phenytoin sodium formulation. Drug Dev Ind Pharm, 29:531–543.
  • Chauhan B, Shimpi S, Paradkar A. (2005). Preparation and characterization of etoricoxib solid dispersions using lipid carriers by spray drying technique. AAPS PharmSciTech, 6:405–412.
  • Galal S, El Massik MA, Abdallah OY, Daabis NA. (2004). Study of in-vitro release characteristics of carbamazepine extended release semisolid matrix filled capsules based on Gelucires. Drug Dev Ind Pharm, 30:817–829.
  • Fouad EA, El-Badry M, Mahrous GM, Alanazi FK, Neau SH, Alsarra IA. (2011). The use of spray-drying to enhance celecoxib solubility. Drug Dev Ind Pharm, 37:1463–1472.
  • Yassin AE, Alanazi FK, El-Badry M, Alsarra IA, Barakat NS, Alanazi FK. (2009). Preparation and characterization of spironolactone-loaded gelucire microparticles using spray-drying technique. Drug Dev Ind Pharm, 35:297–304.
  • Larry L, Albert W, Umang S, Huijeong A. (2006).Super disintegrants: Characterization and function. In: Encyclopedia of Pharmaceutical Technology. Vol. 1. New York: Marcel Deker Inc, 2623–2638.
  • Caramella C, Olumbo O, Conte U, Gazzaniga A, LaManna A. (1984). The role of swelling in the disintegration process. Inter J Pharm Tech, 5:1–5.
  • Caramella C, Colombo P, Conte U, LaManna A. (1987). Tablet disintegration update: The dynamic approach. Drug Dev Ind Pharm 13:2111–2145.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.