Novel taste-masked orally disintegrating tablets for a highly soluble drug with an extremely bitter taste: design rationale and evaluation

References

• Abdelbary G, Prinderre P, Eouani C, Joachim J, Reynier JP, Piccerelle P. (2004). The preparation of orally disintegrating tablets using a hydrophilic waxy binder. Int J Pharm, 278:423–433.
   PubMed Web of Science ®Google Scholar
• Shah PP, Mashru RC. (2008). Development and evaluation of artemether taste masked rapid disintegrating tablets with improved dissolution using solid dispersion technique. AAPS PharmSciTech, 9:494–500.
   PubMed Web of Science ®Google Scholar
• Dobetti L. (2001). Fast-melting tablets: developments and technologies. Pharm Technol, 44–50.
   Google Scholar
• Masaki K. (1997). Orally disintegrating famotidine tablets, 22nd Conference on Pharmaceutical Technology. pp 15–17.
   Google Scholar
• Mizumoto T, Tamura T, Kawai H, Kajiyama A, Itai S. (2008). Formulation design of taste-masked particles, including famotidine, for an oral fast-disintegrating dosage form. Chem Pharm Bull, 56:530–535.
   PubMed Web of Science ®Google Scholar
• Sammour OA, Hammad MA, Megrab NA, Zidan AS. (2006). Formulation and optimization of mouth dissolve tablets containing rofecoxib solid dispersion. AAPS PharmSciTech, 7:1–9.
   PubMedGoogle Scholar
• Katou S, Kearney P, Yarwood RJ. (1993). The zydis fast dissolving oral dosage form. Pharm Tech Jpn 9:713–719.
   Google Scholar
• Wehling F, Schuehle S, Madamala N. Effervescent dosage form and method of administering same. 1991, WO91/04757.
   Google Scholar
• Cousin G, Bruna E, Madamala N. Rapidly disintegratable multiparticular tablet. 1995, US Patent 5464632.
   Google Scholar
• Kluwe WM, Page JG, Toft JD, Ridder WE, Chung H. (1990). Pharmacological and toxicological evaluation of orally administered pyridostigmine in dogs. Fundam Appl Toxicol, 14:40–53.
   PubMedGoogle Scholar
• Tan QY, Hu NN, Liu GD, Yin HF, Zhang L, Wang H et al. (2012). Role of a novel pyridostigmine bromide-phospholipid nanocomplex in improving oral bioavailability. Arch Pharm Res, 35:499–508.
   PubMed Web of Science ®Google Scholar
• Tan QY, Xu ML, Wu JY, Yin HF, Zhang JQ. (2012). Preparation and characterization of poly(lactic acid) nanoparticles for sustained release of pyridostigmine bromide. Pharmazie, 67:311–318.
   PubMed Web of Science ®Google Scholar
• Randale SA, Dabhi CS, Tekade AR, Belgamwar VS, Gattani SG, Surana SJ. (2010). Rapidly disintegrating tablets containing taste masked metoclopramide hydrochloride prepared by extrusion-precipitation method. Chem Pharm Bull, 58:443–448.
   PubMed Web of Science ®Google Scholar
• Xu J, Bovet LL, Zhao K. (2008). Taste masking microspheres for orally disintegrating tablets. Int J Pharm, 359:63–69.
   PubMed Web of Science ®Google Scholar
• Yan YD, Woo JS, Kang JH, Yong CS, Choi HG. (2010). Preparation and evaluation of taste-masked donepezil hydrochloride orally disintegrating tablets. Biol Pharm Bull, 33:1364–1370.
   PubMed Web of Science ®Google Scholar
• Jijun F, Lishuang X, Xiaoli W, Shu Z, Xiaoguang T, Xingna Z et al. (2011). Nimodipine (NM) tablets with high dissolution containing NM solid dispersions prepared by hot-melt extrusion. Drug Dev Ind Pharm, 37:934–944.
   PubMed Web of Science ®Google Scholar
• Funasaki N, Uratsuji I, Okuno T, Hirota S, Neya S. (2006). Masking mechanisms of bitter taste of drugs studied with ion selective electrodes. Chem Pharm Bull, 54:1155–1161.
   PubMed Web of Science ®Google Scholar
• Kayumba PC, Huyghebaert N, Cordella C, Ntawukuliryayo JD, Vervaet C, Remon JP. (2007). Quinine sulphate pellets for flexible pediatric drug dosing: formulation development and evaluation of taste-masking efficiency using the electronic tongue. Eur J Pharm Biopharm, 66:460–465.
   PubMed Web of Science ®Google Scholar
• Laitinen R, Suihko E, Bjorkqvist M, Riikonen J, Lehto VP, Jarvinen K et al. (2010). Perphenazine solid dispersions for orally fast-disintegrating tablets: physical stability and formulation. Drug Dev Ind Pharm, 36:601–613.
   PubMed Web of Science ®Google Scholar
• Rahman Z, Zidan AS, Khan MA. (2010). Risperidone solid dispersion for orally disintegrating tablet: its formulation design and non-destructive methods of evaluation. Int J Pharm, 400:49–58.
   PubMed Web of Science ®Google Scholar
• Otsuka T, Iwao Y, Miyagishima A, Itai S. (2011). Application of principal component analysis enables to effectively find important physical variables for optimization of fluid bed granulator conditions. Int J Pharm, 409:81–88.
   PubMed Web of Science ®Google Scholar
• Law SL, Chiang CH. (1990). Improving dissolution rates of griseofulvin by deposition on disintegrants. Drug Develop Ind Pharm, 16:137–147.
   Web of Science ®Google Scholar
• Gao Y, Cui FD, Guan Y, Yang L, Wang YS, Zhang LN. (2006). Preparation of roxithromycin-polymeric microspheres by the emulsion solvent diffusion method for taste masking. Int J Pharm, 318:62–69.
   PubMed Web of Science ®Google Scholar
• Zhang JQ, Liu J, Li XL, Jasti BR. (2007). Preparation and characterization of solid lipid nanoparticles containing silibinin. Drug Deliv, 14:381–387.
   PubMed Web of Science ®Google Scholar
• Tan QY, Wang N, Yang H, Chen L, Xiong HR, Zhang LK et al. (2010). Preparation and characterization of lipid vesicles containing uricase. Drug Deliv, 17:28–37.
   PubMed Web of Science ®Google Scholar
• Ye G, Wang S, Heng PW, Chen L, Wang C. (2007). Development and optimization of solid dispersion containing pellets of itraconazole prepared by high shear pelletization. Int J Pharm, 337:80–87.
   PubMed Web of Science ®Google Scholar
• Bourne DWA. (2009). Chapter 3, Pharmacokinetics in Modern Pharmaceutics. In: Florence AT, Siepmann J. eds., Volume 1 Basic Principles and Systems, 5th ed. New York, NY:Informa Healthcare. 81–116.
   Google Scholar
• Ermer JC, Dennis K, Haffey MB, Doll WJ, Sandefer EP, Buckwalter M et al. (2011). Intranasal versus oral administration of lisdexamfetamine dimesylate: a randomized, open-label, two-period, crossover, single-dose, single-centre pharmacokinetic study in healthy adult men. Clin Drug Investig, 31:357–370.
   PubMed Web of Science ®Google Scholar
• Liu YM, Liu GY, Liu Y, Li SJ, Jia JY, Zhang MQ et al. (2009). Pharmacokinetic and bioequivalence comparison between orally disintegrating and conventional tablet formulations of flurbiprofen: a single-dose, randomized-sequence, open-label, two-period crossover study in healthy Chinese male volunteers. Clin Ther, 31:1787–1795.
   PubMed Web of Science ®Google Scholar
• Tan QY, Wang N, Yang H, Zhang LK, Liu S, Chen L et al. (2010). Characterization, stabilization and activity of uricase loaded in lipid vesicles. Int J Pharm, 384:165–172.
   PubMed Web of Science ®Google Scholar
• Husain MA, Roberts JB, Thomas BH, Wilson A. (1968). The excretion and metabolism of oral 14C-pyridostigmine in the rat. Br J Pharmacol, 34:445–450.
   PubMed Web of Science ®Google Scholar
• Zhang JQ, Zhang ZR, Yang H, Tan QY, Qin SR, Qiu XL. (2005). Lyophilized paclitaxel magnetoliposomes as a potential drug delivery system for breast carcinoma via parenteral administration: in vitro and in vivo studies. Pharm Res, 22:573–583.
   PubMed Web of Science ®Google Scholar
• Tan QY, Zhang JQ, Wang N, Yang H, Li X, Xiong HR, Wu JY, Zhao CJ, Wang H, Yin HF. (2012). Improved biological properties and hypouricaemic effects of uricase from Candida utilis loaded in novel alkaline enzymosomes. Int J Nanomedicine, 7:3929 –3938
   PubMed Web of Science ®Google Scholar
• Lu B, Zhang JQ, Yang H. (2003). Nonphospholipid vesicles of Carboplatin for lung targeting. Drug Deliv, 10:87–94.
   PubMed Web of Science ®Google Scholar
• Huang YT, Tsai TR, Cheng CJ, Cham TM, Lai TF, Chuo WH. (2007). Formulation design of a highly hygroscopic drug (pyridostigmine bromide) for its hygroscopic character improvement and investigation of in vitro/in vivo dissolution properties. Drug Dev Ind Pharm, 33:403–416.
   PubMed Web of Science ®Google Scholar
• Shukla D, Chakraborty S, Singh S, Mishra B. (2009). Fabrication and evaluation of taste masked resinate of risperidone and its orally disintegrating tablets. Chem Pharm Bull, 57:337–345.
   PubMed Web of Science ®Google Scholar
• Pedersen AM, Bardow A, Jensen SB, Nauntofte B. (2002). Saliva and gastrointestinal functions of taste, mastication, swallowing and digestion. Oral Dis, 8:117–129.
   PubMed Web of Science ®Google Scholar