350
Views
19
CrossRef citations to date
0
Altmetric
Research Article

Budesonide/cyclodextrin complex-loaded lyophilized microparticles for intranasal application

, &
Pages 743-748 | Received 15 Nov 2012, Accepted 27 Feb 2013, Published online: 03 Apr 2013

References

  • Benninger MS, Anon J, Marby RL. The medical management of rhinosinustis. Otolaryngol Head Neck Surg 1997;117:S41–9
  • LaForce C, Raleigh NC. Use of nasal steroids in managing allergic rhinitis. J Allergy Clin Immunol 1999;103:S388–94
  • Meltzer EO. An overview of current pharmacotherapy in perennial rhinitis. J Allergy Clin Immunol 1995;95:1097–110
  • Mygind N. Glucocorticosteroids and rhinitis. Allergy 1993;48:476–90
  • Onrust SV, Lamb HM. Mometasone furoate: a review of its intranasal use in allergic rhinitis. Drugs 1998;56:725–45
  • Szefler SJ. Pharmacokinetics of intranasal corticosteroids. J Allergy Clin Immunol 2001;108:S26–31
  • Malo JL, Cartier A, Ghezzo H, et al. Skin brushing, adrenal function and markers of bone metabolism in asthmatics using inhaled beclomethasone and fluticasone. Eur J Respir 1999;13:993–8
  • Pedersen S, ÓByrne P. A comparison of the efficacy and safety of inhaled corticosteroids in asthma. Allergy 1997;52:1–34
  • Szefler SJ. Pharmacodynamics and pharmacokinetics of budesonide: a new nebulized corticosteroid. J Allergy Clin Immunol 1999;104:175–83
  • Stanley JS, Denver C. Pharmacokinetics of intranasal corticosteroids. J Allergy Clin Immunol 2001;108:S26–31
  • Bandi N, Wei W, Roberts CB, et al. Preparation of budesonide- and indomethacin-hydroxypropyl-beta-cyclodextrin (HPBCD) complexes using a single step, organic-solvent-free supercritical fluid process. Eur J Pharm Sci 2004;23:159–68
  • Joshi MR, Misra A. Liposomal budesonide for dry powder inhaler: preparation and stabilization. AAPS PharmSciTech 2001;2:25–31
  • Parmar JJ, Singh DJ, Hedge DD, et al. Development and evaluation of inhalational liposomal system of budesonide for better management of asthma. Indian J Pharm Sci 2010;72:442–8
  • Buttini F, Colombo P, Wenger MP, et al. Back to basics: the development of a simple, homogenous, two-component dry-powder inhaler formulation for the delivery of budesonide using miscible vinyl polymers. J Pharm Sci 2008;97:1257–67
  • Mezzena M, Scalia S, Young PM, Traini D. Solid lipid budesonide microparticles for controlled release inhalation therapy. AAPS J 2009;11:771–8
  • El-Gendy N, Gorman EM, Monson EJ, Berkland C. Budesonide agglomerates as dry powder aerosols with rapid dissolution. J Pharm Sci 2009;98:2731–46
  • Surti N, Misra A. Wheat germ agglutinin-conjugated nanoparticles for sustained cellular and lung delivery of budesonide. Drug Deliv 2008;15:81–6
  • Lenhardt T, Vergnault G, Grenier P, et al. Evaluation of nanosuspensions for absorption enhancement of poorly soluble drugs: in vitro transport studies across intestinal epithelial monolayers. AAPS J 2008;10:435–8
  • Yang JZ, Young AL, Chiang PC, et al. Fluticasone and budesonide nanosuspensions for pulmonary delivery: preparation, characterization and pharmacokinetic studies. J Pharm Sci 2008;97:4869–78
  • Amani A, York P, Chrystyn H, Clark BJ. Evaluation of a nanoemulsion-based formulation for respiratory delivery of budesonide by nebulizers. AAPS PharmSciTech 2010;11:1147–51
  • Liu H, Zhou LL, Wei LL, et al. Preparation of budesonide-poly(ethylene oxide) solid dispersions using supercritical fluid technology. Drug Dev Ind Pharm 2007;33:959–66
  • Toropainen T, Velaga S, Heikkilä T, et al. Preparation of budesonide/gamma-cyclodextrin complexes in supercritical fluids with a novel SEDS method. J Pharm Sci 2006;95:2235–45
  • Ozdemir N, Erkin J. Enhancement of dissolution rate and bioavailability of sulfamethoxazole by complexation with β-cyclodextrin. Drug Dev Ind Pharm 2012;38:331–40
  • Jug M, Maestrelli F, Bragagni M, Mura P. Preparation and solid-state characterization of bupivacaine hydrochloride cyclodextrin complexes aimed for buccal delivery. J Pharm Biomed Anal 2010;52:9–18
  • Loftsson T, Duchêne D. Cyclodextrins and their pharmaceutical applications. Int J Pharm 2007;329:1–11
  • Balakrishnan P, Yoo BK, Woo JS, et al. Enhanced bioavailability of poorly water-soluble clotrimazole by inclusion with beta-cyclodextrin. Arch Pharm Res 2007;2:249–54
  • Cho HJ, Balakrishnan P, Shim WS, et al. Characterization and in vitro evaluation of freeze-dried microparticles composed of granisetron-cyclodextrin complex and carboxymethylcellulose for intranasal delivery. Int J Pharm 2010;400:59–65
  • Loftsson T, Vogensen SB, Brewster ME, Konrádsdóttir F. Effects of cyclodextrins on drug delivery through biological membranes. J Pharm Sci 2007;96:2532–46
  • Cho HJ, Balakrishnan P, Chung SJ, et al. Evaluation of protein stability and in vitro permeation of lyophilized polysaccharides-based microparticles for intranasal protein delivery. Int J Pharm 2011;416:77–84
  • Carrier RL, Miller LA, Ahmed I. The utility of cyclodextrins for enhancing oral bioavailability. J Control Release 2007;123:78–99
  • Dyvik K, Graffner C. Investigation of the applicability of a tensile testing machine for measuring mucoadhesive strength. Acta Pharm Nord 1992;4:79–84
  • Henriksen I, Green KL, Smart JD, et al. Bioadhesion hydrated chitosans: an in vitro and in vivo study. Int J Pharm 1996;145:231–40
  • Burdock GA. Safety assessment of hydroxypropyl methylcellulose as a food ingredient. Food Chem Toxicol 2007;45:2341–51
  • Ugwoke MI, Agu RU, Vanbilloen H, et al. Scintigraphic evaluation in rabbits of nasal drug delivery systems based on carbopol 971p((R)) and carboxymethylcellulose. J Control Release 2000;68:207–14
  • Ugwoke MI, Agu RU, Jorissen M, et al. Toxicological investigations of the effects carboxymethylcellulose on ciliary beat frequency of human nasal epithelial cells in primary suspension culture and in vivo on rabbit nasal mucosa. Int J Pharm 2000;205:43–51
  • Higuchi T, Connors K. Phase solubility techniques. Adv Anal Chem Instrum 1965;7:117–212
  • Cho HJ, Balakrishnan P, Lin H, et al. Application of biopharmaceutics classification system (BCS) in drug transport studies across human respiratory epithelial cell monolayers. J Pharm Invest 2012;42:147–53
  • Lee MK, Yoo JW, Lin H, et al. Serially passaged human nasal epithelial cell monolayer for drug transport studies: comparison between liquid-cover condition (LCC) and air-liquid interface (ALI) culture condition. Drug Deliv 2005;12:305–11
  • Merkus FWHM, Verhoef JC, Marttin E, et al. Cyclodextrins in nasal drug delivery. Adv Drug Deliv Rev 1999;36:41–57
  • Ugwoke MI, Verbeke N, Kinget R. The biopharmaceutical aspects of nasal mucoadhesive drug delivery. J Pharm Pharmacol 2001;53:3–21
  • Wang Z, Deng Y, Sun S, Zhang X. Preparation of hydrophobic drugs cyclodextrin complex by lyophilization monophase solution. Drug Dev Ind Pharm 2006;32:73–83
  • Martin TA, Bandi N, Schulz R, et al. Preparation of budesonide and budesonide-PLA microparticles using supercritical fluid precipitation technology. AAPS PharmSciTech 2002;3:16–26
  • Chowdary KP, Srinivas SV. Influence of hydrophilic polymers on celecoxib complexation with hydroxypropyl-beta-cyclodextrin. AAPS PharmSciTech 2006;7:E184–9
  • Cirri M, Righi MF, Maestrelli F, et al. Development of glyburide fast-dissolving tablets based on the combined use of cyclodextrins and polymers. Drug Dev Ind Pharm 2009;35:73–82
  • Singh SK, Srinivasan KK, Singare DS, et al. Formulation of ternary complexes of glyburide with hydroxypropyl-β-cyclodextrin and other solubilizing agents and their effect on release behavior of glyburide in aqueous and buffered media at different agitation speeds. Drug Dev Ind Pharm 2012;38:1328–36
  • Borghetti GS, Pinto AP, Lula IS, et al. Daidzein/cyclodextrin/hydrophilic polymer ternary systems. Drug Dev Ind Pharm 2011;37:886–93

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.